Human gastric cancer organizes neighboring lymphatic vessels via recruitment of bone marrow-derived lymphatic endothelial progenitor cells

Journal of Gastroenterology

Volumn 47, Issue 9, 2012, Pages 1057-1060

  Tawada, Masahiro ^a   Hayashi, Shin Ichiro ^a   Osada, Shinji ^a   Nakashima, Shigeru ^a   Yoshida, Kazuhiro ^a  

^a GIFU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Bone marrow; Human gastric cancer; Lymphangiogenesis; Lymphatic endothelial progenitor cells

Indexed keywords

GREEN FLUORESCENT PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE MARROW; BONE MARROW TRANSPLANTATION; CARCINOGENESIS; CELL FUNCTION; CONTROLLED STUDY; ENDOTHELIAL PROGENITOR CELL; HUMAN; HUMAN CELL; LYMPH VESSEL; LYMPHANGIOGENESIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; STOMACH CANCER; TUMOR BIOPSY; TUMOR XENOGRAFT;

ADENOCARCINOMA; ANIMALS; BONE MARROW; ENDOTHELIAL CELLS; HUMANS; LYMPHANGIOGENESIS; LYMPHATIC VESSELS; MICE; MICE, NUDE; MICROSCOPY, FLUORESCENCE; STEM CELLS; STOMACH NEOPLASMS; TUMOR CELLS, CULTURED;

EID: 84867581541     PISSN: 09441174     EISSN: 14355922     Source Type: Journal    
DOI: 10.1007/s00535-012-0638-4     Document Type: Article

References (8)

1. Achen MG, McColl BK, Stacker SA. Focus on lymphangiogenesis in tumor metastasis. Cancer Cell. 2005;7:121-7.
2. Banerji S, Ni J, Wang SX, Clasper S, Su J, Tammi R, et al. LYVE- 1, a new homologue of the CD44 glycoprotein, is a lymph-specific receptor for hyaluronan. J Cell Biol. 1999;144:789-801.
3. Alitaro K, Tammela T, Petrova TV. Lymphoangiogenesis in development and human disease. Nature. 2005;438:946-53.
4. Kerjaschki D, Huttary N, Raab I, Regele H, Bojarshi-Nagy K, Bartel G, et al. Lymphatic endothelial progenitor cells contribute to de novo lymphangiogenesis in human renal transplants. Nat Med. 2006;12:230-4.
5. He Y, Rajantie I, Ilmonen M, Maikinen T, Karkkainen MJ, Haiko P, et al. Preexisting lymphatic endothelium but not endothelial progenitor cells are essential for tumor lymphangiogenesis and lymphatic metastasis. Cancer Res. 2004;64:3737-40.
6. Asahara T, Masuda H, Takahashi T, Kalka C, Pastore C, Silver M, et al. Bone marrow origin of endothelial progenitor cells responsible for postnatal vasculogenesis in physiological and pathological neovascularization. Circ Res. 1999;85:221-8.
7. Lyden D, Hattori K, Dias S, Costa C, Blaikie P, Butros L, et al. Impaired recruitment of bone-marrow-derived endothelial and hematopoietic precursor cells blocks tumor angiogenesis and growth. Nat Med. 2001;7:1194-201.
8. Rocco A, Liguori E, Pirozzi G, Tirino V, Compare D, Franco R, et al. CD133 and CD44 cell surface markers do not identify cancer stem cells in primary human gastric tumors. J Cell Physiol. 2012;227:2686-93.