Comparison of endothelin receptors in normal versus cirrhotic human liver and in the liver from endothelial cell-specific ETB knockout mice

Life Sciences

Volumn 91, Issue 13-14, 2012, Pages 716-722

  Ling, Lowell ^a   Kuc, Rhoda E ^a   Maguire, Janet J ^a   Davie, Neil J ^b   Webb, David J ^c   Gibbs, Paul ^d   Alexander, Graeme J M ^d   Davenport, Anthony P ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b PFIZER GLOBAL RESEARCH AND DEVELOPMENT   (United Kingdom)

^c UNIVERSITY OF EDINBURGH   (United Kingdom)

^d CAMBRIDGE UNIVERSITY HOSPITALS NHS FOUNDATION TRUST   (United Kingdom)

Author keywords

Ambrisentan; Antagonist; Endothelin receptors; ETA ETB; Hepatotoxicity; Liver; Portal hypertension; Sitaxentan

Indexed keywords

AMBRISENTAN; ENDOTHELIN A RECEPTOR; ENDOTHELIN B RECEPTOR; SITAXSENTAN;

ANIMAL CELL; ANIMAL TISSUE; AUTORADIOGRAPHY; BINDING ASSAY; CONFERENCE PAPER; CONTROLLED STUDY; DOWN REGULATION; DRUG SELECTIVITY; ENDOTHELIUM CELL; ERYTHROCYTE; HEPATIC ARTERY; HUMAN; HUMAN TISSUE; IMMUNOFLUORESCENCE; INFORMATION PROCESSING; KNOCKOUT MOUSE; LIVER CIRRHOSIS; LIVER PARENCHYMA; LIVER SINUSOID; LIVER VEIN; MOUSE; NONHUMAN; PORTAL VEIN; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; UPREGULATION;

ANIMALS; AUTORADIOGRAPHY; BINDING, COMPETITIVE; HEPATIC ARTERY; HUMANS; ISOXAZOLES; LIVER; LIVER CIRRHOSIS; MICE; MICE, KNOCKOUT; MICROSCOPY, FLUORESCENCE; PHENYLPROPIONATES; PORTAL VEIN; PYRIDAZINES; RECEPTOR, ENDOTHELIN A; RECEPTOR, ENDOTHELIN B; THIOPHENES; UP-REGULATION;

ANIMALIA; MURINAE; MUS;

EID: 84867574727     PISSN: 00243205     EISSN: 18790631     Source Type: Journal    
DOI: 10.1016/j.lfs.2012.02.003     Document Type: Conference Paper

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