Endothelin B receptors located on the endothelium provide cardiovascular protection in the hamster

Clinical Science

Volumn 103, Issue SUPPL. 48, 2002, Pages

  Honoré, Jean Claude ^a   Proteau, Caroline ^a   D'Orléans Juste, Pedro ^a  

^a UNIVERSITÉ DE SHERBROOKE   (Canada)

Author keywords

Blood pressure; ETA and ETB receptors; Reverse transcriptase PCR

Indexed keywords

CYCLO(DEXTRO TRYPTOPHYL DEXTRO ASPARTYLPROLYL DEXTRO VALYLLEUCYL); ENDOTHELIN; ENDOTHELIN A RECEPTOR; ENDOTHELIN A RECEPTOR ANTAGONIST; ENDOTHELIN B RECEPTOR; ENDOTHELIN B RECEPTOR ANTAGONIST; N (2,6 DIMETHYLPIPERIDINOCARBONYL) 4 METHYLLEUCYL DEXTRO (1 METHOXYCARBONYLTRYPTOPHANYL) DEXTRO NORLEUCINE; SUCCINYLENDOTHELIN 1 [8-21][9 GLUTAMIC ACID 11,15 ALANINE];

ANIMAL EXPERIMENT; ANIMAL MODEL; BLOOD VESSEL TONE; CARDIOMYOPATHY; CONFERENCE PAPER; CONTROLLED STUDY; HAMSTER; HEART PROTECTION; HEMODYNAMICS; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; RECEPTOR BLOCKING; RECEPTOR INTRINSIC ACTIVITY; RECEPTOR UPREGULATION; VASOCONSTRICTION;

EID: 0036671061     PISSN: 01435221     EISSN: None     Source Type: Journal    
DOI: 10.1042/cs103s280s     Document Type: Conference Paper

References (14)

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3. Clearance of circulating endothelin-1 by ETB receptors in rats
4. Evidence for vasoconstriction mediated by the endothelin-B receptor in domestic swine
5. Venous smooth muscle contains vasoconstrictor ETB-like receptors
6. Both ETA and ETB receptors mediate contraction to endothelin-1 in human blood vessels
7. Endothelin B receptors are functionally important in mediating vasoconstriction in the systemic circulation in patients with left ventricular systolic dysfunction
8. Systemic blockade of the endothelin-B receptor increases peripheral vascular resistance in healthy men
9. Cardiomyopathic Syrian hamster: A possible model of human disease
10. Role of endothelin in deterioration of heart failure due to cardiomyopathy in hamsters: Increase in endothelin-1 production in the heart and beneficial effect of endothelin-A receptor antagonist on survival and cardiac function
11. Biological profiles of highly potent novel endothelin antagonists selective for the ETA receptor
12. Biochemical and pharmacological profile of a potent and selective endothelin B-receptor antagonist, BQ-788
13. Expression of endothelin receptors in human myometrium during pregnancy and in uterine leiomyomas
14. Endothelin-A receptor antagonist-mediated vasodilatation is attenuated by inhibition of nitric oxide synthesis and by endothelin-B receptor blockade