Hepatic toxicity after radioembolization of the liver using 90Y-microspheres: Sequential lobar versus whole liver approach

CardioVascular and Interventional Radiology

Volumn 35, Issue 5, 2012, Pages 1109-1118

  Seidensticker, Ricarda ^a   Seidensticker, Max ^a   Damm, Robert ^a   Mohnike, Konrad ^a   Schütte, Kerstin ^a   Malfertheiner, Peter ^a   Van Buskirk, Mark ^b   Pech, MacIej ^a   Amthauer, Holger ^a   Ricke, Jens ^a  

^a UNIVERSITY HOSPITAL MAGDEBURG   (Germany)

^b Data Reduction   (United States)

Author keywords

Hepatic metastases; Hepatic toxicity; Local ablation; Radiation induced liver disease; REILD; RILD; Yttrium 90

Indexed keywords

GADOXETIC ACID; MICROSPHERE Y 90; RADIOACTIVE MICROSPHERE; UNCLASSIFIED DRUG;

ADULT; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ALBUMIN BLOOD LEVEL; ALKALINE PHOSPHATASE BLOOD LEVEL; ARTICLE; ARTIFICIAL EMBOLISM; ASCITES; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; BILIRUBIN BLOOD LEVEL; CANCER RADIOTHERAPY; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; FOLLOW UP; GAMMA GLUTAMYL TRANSFERASE BLOOD LEVEL; HUMAN; HYPERBILIRUBINEMIA; INTERMETHOD COMPARISON; LIVER DISEASE; LIVER HYPERTROPHY; LIVER METASTASIS; LIVER TOXICITY; LIVER VENOOCCLUSIVE DISEASE; LIVER WEIGHT; MALE; NUCLEAR MAGNETIC RESONANCE IMAGING; PLEURA EFFUSION; PORTAL VEIN; PRIORITY JOURNAL; RADIATION INJURY; RADIOEMBOLIZATION; RADIOEMBOLIZATION INDUCED LIVER DISEASE; SIDE EFFECT; SPLEEN; SPLEEN VOLUME; TUMOR VOLUME; VEIN DIAMETER;

EMBOLIZATION, THERAPEUTIC; FEMALE; HUMANS; LIVER FUNCTION TESTS; LIVER NEOPLASMS; MALE; MICROSPHERES; MIDDLE AGED; STATISTICS, NONPARAMETRIC; SURVIVAL RATE; TREATMENT OUTCOME; YTTRIUM RADIOISOTOPES;

EID: 84867574344     PISSN: 01741551     EISSN: 1432086X     Source Type: Journal    
DOI: 10.1007/s00270-011-0295-7     Document Type: Article

References (30)

1. Wallace S, Carrasco CH, Charnsangavej C et al (1990) Hepatic artery infusion and chemoembolization in the management of liver metastases. Cardiovasc Intervent Radiol 13(3):153-160
2. Cosimelli M, Golfieri R, Cagol PP et al (2010) Multi-centre phase II clinical trial of yttrium-90 resin microspheres alone in unresectable, chemotherapy refractory colorectal liver metastases. Br J Cancer 103(3):324-331
3. Gray B, Van Hazel G, Hope M et al (2001) Randomised trial of SIR-Spheres plus chemotherapy vs chemotherapy alone for treating patients with liver metastases from primary large bowel cancer. Ann Oncol 12(12):1711-1720
4. Mulcahy MF, Lewandowski RJ, Ibrahim SM et al (2009) Radioembolization of colorectal hepatic metastases using yttrium-90 microspheres. Cancer 115(9):1849-1858
5. Hilgard P, Hamami M, Fouly AE et al (2010) Radioembolization with yttrium-90 glass microspheres in hepatocellular carcinoma: European experience on safety and long-term survival. Hepatology 52(5):1741-1749
6. Kennedy A, Nag S, Salem R et al (2007) Recommendations for radioembolization of hepatic malignancies using yttrium-90 microsphere brachytherapy: a consensus panel report from the radioembolization brachytherapy oncology consortium. Int J Radiat Oncol Biol Phys 68(1):13-23
7. Nicolay NH, Berry DP, Sharma RA (2009) Liver metastases from colorectal cancer: radioembolization with systemic therapy. Nat Rev Clin Oncol 6(12):687-697
8. Sharma RA, van Hazel GA, Morgan B et al (2007) Radioembolization of liver metastases from colorectal cancer using yttrium-90 microspheres with concomitant systemic oxaliplatin, fluorouracil, and leucovorin chemotherapy. J Clin Oncol 25(9):1099-1106
9. van Hazel GA, Pavlakis N, Goldstein D et al (2009) Treatment of fluorouracil-refractory patients with liver metastases from colorectal cancer by using yttrium-90 resin microspheres plus concomitant systemic irinotecan chemotherapy. J Clin Oncol 27(25):4089-4095
10. Salem R, Lewandowski RJ, Kulik L et al (2011) Radioembolization results in longer time-to-progression and reduced toxicity compared with chemoembolization in patients with hepatocellular carcinoma. Gastroenterology 140(2):497-507
11. 90yttrium- microspheres for inoperable hepatic tumors. Int J Radiat Oncol Biol Phys 33(4):919-924
12. Sangro B, Gil-Alzugaray B, Rodriguez J et al (2008) Liver disease induced by radioembolization of liver tumors: description and possible risk factors. Cancer 112(7):1538-1546
13. Bianco JA, Appelbaum FR, Nemunaitis J et al (1991) Phase I-II trial of pentoxifylline for the prevention of transplant-related toxicities following bone marrow transplantation. Blood 78(5):1205-1211
14. Essell JH, Schroeder MT, Harman GS et al (1998) Ursodiol prophylaxis against hepatic complications of allogeneic bone marrow transplantation. A randomized, double-blind, placebo-controlled trial. Ann Intern Med 128(12 Pt 1):975-981
15. Forrest DL, Thompson K, Dorcas VG et al (2003) Low molecular weight heparin for the prevention of hepatic veno-occlusive disease (VOD) after hematopoietic stem cell transplantation: a prospective phase II study. Bone Marrow Trans 31(12):1143-1149
16. Ricke J, Seidensticker M, Ludemann L et al (2005) In vivo assessment of the tolerance dose of small liver volumes after single-fraction HDR irradiation. Int J Radiat Oncol Biol Phys 62(3):776-784
17. Seidensticker M, Seidensticker R, Mohnike K et al (2011) Quantitative in vivo assessment of radiation injury of the liver using Gd-EOB-DTPA enhanced MRI: tolerance dose of small liver volumes. Radiat Oncol 6:40
18. Field KM, Dow C, Michael M (2008) Part I: liver function in oncology: biochemistry and beyond. Lancet Oncol 9(11):1092-1101
19. Deleporte A, Flamen P, Hendlisz A (2010) State of the art: radiolabeled microspheres treatment for liver malignancies. Expert Opin Pharmacother 11(4):579-586
20. Hermann RM, Rave-Frank M, Pradier O (2008) Combining radiation with oxaliplatin: a review of experimental results. Cancer Radiother 12(1):61-67
21. Rubbia-Brandt L, Audard V, Sartoretti P et al (2004) Severe hepatic sinusoidal obstruction associated with oxaliplatin-based chemotherapy in patients with metastatic colorectal cancer. Ann Oncol 15(3):460-466
22. Denecke T, Ruhl R, Hildebrandt B et al (2008) Planning transarterial radioembolization of colorectal liver metastases with Yttrium 90 microspheres: evaluation of a sequential diagnostic approach using radiologic and nuclear medicine imaging techniques. Eur Radiol 18(5):892-902
23. Seidensticker R, Denecke T, Kraus P et al (2011) Matched-pair comparison of radioembolization plus best supportive care versus best supportive care alone for chemotherapy refractory liver-dominant colorectal metastases. Cardiovasc Intervent Radiol (in press)
24. Salem R, Lewandowski RJ, Gates VL et al (2011) Research reporting standards for radioembolization of hepatic malignancies. J Vasc Interv Radiol 22(3):265-278
25. Fajardo LF, Colby TV (1980) Pathogenesis of veno-occlusive liver disease after radiation. Arch Pathol Lab Med 104(11):584-588
26. Bayraktar UD, Seren S, Bayraktar Y (2007) Hepatic venous outflow obstruction: three similar syndromes. World J Gastroenterol 13(13):1912-1927
27. DeLeve LD, Shulman HM, McDonald GB (2002) Toxic injury to hepatic sinusoids: sinusoidal obstruction syndrome (veno-occlusive disease). Semin Liver Dis 22(1):27-42
28. 90yttrium microspheres. Dig Dis Sci 53(9):2556-2563
29. Dawson LA, Normolle D, Balter JM et al (2002) Analysis of radiation-induced liver disease using the Lyman NTCP model. Int J Radiat Oncol Biol Phys 53(4):810-821
30. Lawrence TS, Robertson JM, Anscher MS et al (1995) Hepatic toxicity resulting from cancer treatment. Int J Radiat Oncol Biol Phys 31(5):1237-1248