Quantitative in vivo assessment of radiation injury of the liver using Gd-EOB-DTPA enhanced MRI: Tolerance dose of small liver volumes

Radiation Oncology

Volumn 6, Issue 1, 2011, Pages

  Seidensticker, Max ^a   Seidensticker, Ricarda ^a   Mohnike, Konrad ^a   Wybranski, Christian ^a   Kalinski, Thomas ^a   Luess, Sebastian ^a   Pech, Maciej ^a   Wust, Peter ^b   Ricke, Jens ^a  

^a UNIVERSITY HOSPITAL MAGDEBURG   (Germany)

^b CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

GADOLINIUM PENTETATE; CONTRAST MEDIUM; DIAGNOSTIC AGENT; GADOLINIUM ETHOXYBENZYL DTPA;

ADULT; AGED; ARTICLE; BRACHYTHERAPY; CELL FUNCTION; CELL REGENERATION; CLINICAL ARTICLE; DOSIMETRY; EDEMA; HISTOGRAM; HUMAN; ILEUM DYSFUNCTION; IN VIVO STUDY; IRRADIATION; LIVER CELL; LIVER FUNCTION; LIVER INJURY; LIVER METASTASIS; LIVER WEIGHT; NUCLEAR MAGNETIC RESONANCE IMAGING; QUANTITATIVE ANALYSIS; RADIATION DOSE; RADIATION EXPOSURE; RADIATION INJURY; CLINICAL TRIAL; COMPUTER ASSISTED DIAGNOSIS; COMPUTER ASSISTED RADIOTHERAPY; FEMALE; LIVER; LIVER TUMOR; MALE; METASTASIS; METHODOLOGY; MIDDLE AGED; RADIATION RESPONSE;

ADULT; AGED; AGED, 80 AND OVER; BRACHYTHERAPY; CONTRAST MEDIA; DOSE-RESPONSE RELATIONSHIP, RADIATION; FEMALE; GADOLINIUM DTPA; HUMANS; IMAGE INTERPRETATION, COMPUTER-ASSISTED; LIVER; LIVER NEOPLASMS; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; RADIATION INJURIES; RADIOTHERAPY PLANNING, COMPUTER-ASSISTED;

EID: 79955124170     PISSN: None     EISSN: 1748717X     Source Type: Journal    
DOI: 10.1186/1748-717X-6-40     Document Type: Article

References (36)

1. Herfarth KK, Debus J, Lohr F, Bahner ML, Rhein B, Fritz P, Hoss A, Schlegel W, Wannenmacher MF. Stereotactic single-dose radiation therapy of liver tumors: results of a phase I/II trial. J Clin Oncol 2001, 19:164-170.
2. Kavanagh BD, Schefter TE, Cardenes HR, Stieber VW, Raben D, Timmerman RD, McCarter MD, Burri S, Nedzi LA, Sawyer TE, et al. Interim analysis of a prospective phase I/II trial of SBRT for liver metastases. Acta Oncol 2006, 45:848-855. 10.1080/02841860600904870, 16982549.
3. Ricke J, Wust P, Stohlmann A, Beck A, Cho CH, Pech M, Wieners G, Spors B, Werk M, Rosner C, et al. CT-guided interstitial brachytherapy of liver malignancies alone or in combination with thermal ablation: phase I-II results of a novel technique. Int J Radiat Oncol Biol Phys 2004, 58:1496-1505. 10.1016/j.ijrobp.2003.09.024, 15050329.
4. Ricke J, Mohnike K, Pech M, Seidensticker M, Rühl R, Wieners G, Gaffke G, Kropf S, Felix R, Wust P. Local response and impact on survival after local ablation of liver metastases from colorectal carcinoma by CT-guided HDR-brachytherapy. Int J Radiat Oncol Biol Phys 2009,
5. Herfarth KK, Hof H, Bahner ML, Lohr F, Hoss A, van Kaick G, Wannenmacher M, Debus J. Assessment of focal liver reaction by multiphasic CT after stereotactic single-dose radiotherapy of liver tumors. Int J Radiat Oncol Biol Phys 2003, 57:444-451. 10.1016/S0360-3016(03)00586-8, 12957256.
6. Kim TH, Panahon AM, Friedman M, Webster JH. Acute transient radiation hepatitis following whole abdominal irradiation. Clin Radiol 1976, 27:449-454. 10.1016/S0009-9260(76)80107-9, 1000890.
7. Lawrence TS, Robertson JM, Anscher MS, Jirtle RL, Ensminger WD, Fajardo LF. Hepatic toxicity resulting from cancer treatment. Int J Radiat Oncol Biol Phys 1995, 31:1237-1248. 10.1016/0360-3016(94)00418-K, 7713785.
8. Ricke J, Seidensticker M, Ludemann L, Pech M, Wieners G, Hengst S, Mohnike K, Cho CH, Lopez HE, Al Abadi H, et al. In vivo assessment of the tolerance dose of small liver volumes after single-fraction HDR irradiation. Int J Radiat Oncol Biol Phys 2005, 62:776-784. 10.1016/j.ijrobp.2004.11.022, 15936559.
9. Burman C, Kutcher GJ, Emami B, Goitein M. Fitting of normal tissue tolerance data to an analytic function. Int J Radiat Oncol Biol Phys 1991, 21:123-135.
10. Dawson LA, Normolle D, Balter JM, McGinn CJ, Lawrence TS, Ten Haken RK. Analysis of radiation-induced liver disease using the Lyman NTCP model. Int J Radiat Oncol Biol Phys 2002, 53:810-821. 10.1016/S0360-3016(02)02846-8, 12095546.
11. Emami B, Lyman J, Brown A, Coia L, Goitein M, Munzenrider JE, Shank B, Solin LJ, Wesson M. Tolerance of normal tissue to therapeutic irradiation. Int J Radiat Oncol Biol Phys 1991, 21:109-122.
12. Lewin K, Millis RR. Human radiation hepatitis. A morphologic study with emphasis on the late changes. Arch Pathol 1973, 96:21-26.
13. Reed GB, Cox AJ. The human liver after radiation injury. A form of veno-occlusive disease. Am J Pathol 1966, 48:597-611. 1916442, 5327788.
14. De Bari B, Pointreau Y, Rio E, Mirabel X, Mornex F. Normal tissue tolerance to external beam radiation therapy: liver. Cancer Radiother 2010, 14:344-349.
15. Hamm B, Staks T, Muhler A, Bollow M, Taupitz M, Frenzel T, Wolf KJ, Weinmann HJ, Lange L. Phase I clinical evaluation of Gd-EOB-DTPA as a hepatobiliary MR contrast agent: safety, pharmacokinetics, and MR imaging. Radiology 1995, 195:785-792.
16. Kirchin MA, Pirovano GP, Spinazzi A. Gadobenate dimeglumine (Gd-BOPTA). An overview. Invest Radiol 1998, 33:798-809. 10.1097/00004424-199811000-00003, 9818314.
17. Schuhmann-Giampieri G, Schmitt-Willich H, Press WR, Negishi C, Weinmann HJ, Speck U. Preclinical evaluation of Gd-EOB-DTPA as a contrast agent in MR imaging of the hepatobiliary system. Radiology 1992, 183:59-64.
18. Spinazzi A, Lorusso V, Pirovano G, Taroni P, Kirchin M, Davies A. Multihance clinical pharmacology: biodistribution and MR enhancement of the liver. Acad Radiol 1998, 5(Suppl 1):S86-S89. 10.1016/S1076-6332(98)80069-X, 9561052.
19. Clement O, Muhler A, Vexler V, Berthezene Y, Brasch RC. Gadolinium-ethoxybenzyl-DTPA, a new liver-specific magnetic resonance contrast agent. Kinetic and enhancement patterns in normal and cholestatic rats. Invest Radiol 1992, 27:612-619. 10.1097/00004424-199208000-00010, 1428739.
20. Oude Elferink RP, Jansen PL. The role of the canalicular multispecific organic anion transporter in the disposal of endo- and xenobiotics. Pharmacol Ther 1994, 64:77-97. 10.1016/0163-7258(94)90034-5, 7846117.
21. Pascolo L, Cupelli F, Anelli PL, Lorusso V, Visigalli M, Uggeri F, Tiribelli C. Molecular mechanisms for the hepatic uptake of magnetic resonance imaging contrast agents. Biochem Biophys Res Commun 1999, 257:746-752. 10.1006/bbrc.1999.0454, 10208854.
22. van Montfoort JE, Stieger B, Meijer DK, Weinmann HJ, Meier PJ, Fattinger KE. Hepatic uptake of the magnetic resonance imaging contrast agent gadoxetate by the organic anion transporting polypeptide Oatp1. J Pharmacol Exp Ther 1999, 290:153-157.
23. Muhler A, Weinmann HJ. Biodistribution and excretion of 153Gd-labeled gadolinium ethoxybenzyl diethylenetriamine pentaacetic acid following repeated intravenous administration to rats. Acad Radiol 1995, 2:313-318. 10.1016/S1076-6332(05)80191-6, 9419568.
24. Reimer P, Rummeny EJ, Shamsi K, Balzer T, Daldrup HE, Tombach B, Hesse T, Berns T, Peters PE. Phase II clinical evaluation of Gd-EOB-DTPA: dose, safety aspects, and pulse sequence. Radiology 1996, 199:177-183.
25. Schuhmann-Giampieri G. Liver contrast media for magnetic resonance imaging. Interrelations between pharmacokinetics and imaging. Invest Radiol 1993, 28:753-761. 10.1097/00004424-199308000-00018, 8376008.
26. Weinmann HJ, Schuhmann-Giampieri G, Schmitt-Willich H, Vogler H, Frenzel T, Gries H. A new lipophilic gadolinium chelate as a tissue-specific contrast medium for MRI. Magn Reson Med 1991, 22:233-237. 10.1002/mrm.1910220214, 1812351.
27. Ryeom HK, Kim SH, Kim JY, Kim HJ, Lee JM, Chang YM, Kim YS, Kang DS. Quantitative evaluation of liver function with MRI Using Gd-EOB-DTPA. Korean J Radiol 2004, 5:231-239. 10.3348/kjr.2004.5.4.231, 2698167, 15637473.
28. Fajardo LF, Colby TV. Pathogenesis of veno-occlusive liver disease after radiation. Arch Pathol Lab Med 1980, 104:584-588.
29. Jacobs P, Miller JL, Uys CJ, Dietrich BE. Fatal veno-occlusive disease of the liver after chemotherapy, whole-body irradiation and bone marrow transplantation for refractory acute leukaemia. S Afr Med J 1979, 55:5-10.
30. Shulman HM, McDonald GB, Matthews D, Doney KC, Kopecky KJ, Gauvreau JM, Thomas ED. An analysis of hepatic venocclusive disease and centrilobular hepatic degeneration following bone marrow transplantation. Gastroenterology 1980, 79:1178-1191.
31. Shulman HM, Gown AM, Nugent DJ. Hepatic veno-occlusive disease after bone marrow transplantation. Immunohistochemical identification of the material within occluded central venules. Am J Pathol 1987, 127:549-558. 1899766, 2438942.
32. Geraci JP, Mariano MS. Radiation hepatology of the rat: parenchymal and nonparenchymal cell injury. Radiat Res 1993, 136:205-213. 10.2307/3578612, 8248477.
33. Jirtle RL, Michalopoulos G, McLain JR, Crowley J. Transplantation system for determining the clonogenic survival of parenchymal hepatocytes exposed to ionizing radiation. Cancer Res 1981, 41:3512-3518.
34. Johnson LK, Longenecker JP, Fajardo LF. Differential radiation response of cultured endothelial cells and smooth myocytes. Anal Quant Cytol 1982, 4:188-198.
35. Ruhl R, Seidensticker M, Peters N, Mohnike K, Bornschein J, Schutte K, Amthauer H, Malfertheiner P, Pech M, Ricke J. Hepatocellular carcinoma and liver cirrhosis: assessment of the liver function after Yttrium-90 radioembolization with resin microspheres or after CT-guided high-dose-rate brachytherapy. Dig Dis 2009, 27:189-199. 10.1159/000218352, 19546558.
36. Farthing MJ, Clark ML, Sloane JP, Powles RL, McElwain TJ. Liver disease after bone marrow transplantation. Gut 1982, 23:465-474. 10.1136/gut.23.6.465, 1419702, 7042484.