6-[(1-naphthylmethyl)sulfanyl]-9H-purine induces G2/M phase arrest and apoptosis in human hepatocellular carcinoma HepG2 cells

European Journal of Pharmacology

Volumn 695, Issue 1-3, 2012, Pages 27-33

  Yang, Xiao Guang ^a   Bao, Yong Li ^a   Huang, Yan Xin ^a   Sun, Lu Guo ^a   Zhang, Yu Wei ^a   Yu, Chun Lei ^a   Wu, Yin ^a   Li, Yu Xin ^a  

^a NORTHEAST NORMAL UNIVERSITY   (China)

Author keywords

6 (1 naphthylmethyl)sulfanyl 9H purine; 6 mercaptopurine; Anti cancer; Apoptosis; Compound screening; Proliferation

Indexed keywords

6 [(1 NAPHTHYLMETHYL)SULFANYL] 9H PURINE; ANTINEOPLASTIC AGENT; CASPASE 3; CASPASE 9; CYCLIN B1; CYCLIN D1; CYCLIN DEPENDENT KINASE 4; PROTEIN BAX; PROTEIN BCL 2; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER INHIBITION; CELL STRAIN HEPG2; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG SCREENING; DRUG STRUCTURE; G2 PHASE CELL CYCLE CHECKPOINT; HUMAN; HUMAN CELL; IMMUNOBLOTTING; LIVER CELL CARCINOMA; NICK END LABELING; PRIORITY JOURNAL; PROTEIN EXPRESSION;

6-MERCAPTOPURINE; ANTINEOPLASTIC AGENTS; APOPTOSIS; CARCINOMA, HEPATOCELLULAR; CELL PROLIFERATION; DRUG SCREENING ASSAYS, ANTITUMOR; G2 PHASE CELL CYCLE CHECKPOINTS; HEP G2 CELLS; HUMANS; LIVER NEOPLASMS; M PHASE CELL CYCLE CHECKPOINTS;

EID: 84867572360     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2012.09.004     Document Type: Article

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