A genome-wide scan for quantitative trait loci affecting respiratory disease and immune capacity in Landrace pigs

Animal Genetics

Volumn 43, Issue 6, 2012, Pages 721-729

  Okamura, T ^a,g   Onodera, W ^a   Tayama, T ^a   Kadowaki, H ^b   Kojima Shibata, C ^b   Suzuki, E ^b   Uemoto, Y ^c   Mikawa, S ^d   Hayashi, T ^e   Awata, T ^d   Fujishima Kanaya, N ^f   Mikawa, A ^f   Uenishi, H ^d   Suzuki, K ^a  

^a TOHOKU UNIVERSITY   (Japan)

^b Miyagi Livestock Experimental Station   (Japan)

^c NATIONAL LIVESTOCK BREEDING CENTER   (Japan)

^d NATIONAL INSTITUTE OF AGROBIOLOGICAL SCIENCES   (Japan)

^e NATIONAL AGRICULTURAL RESEARCH CENTER   (Japan)

^f Institute of the Society for Techno innovation of Agriculture   (Japan)

^g NATIONAL INSTITUTE OF LIVESTOCK AND GRASSLAND SCIENCE   (Japan)

Author keywords

atrophic rhinitis; immune capacity; Landrace purebred population; mycoplasmal pneumonia; quantitative trait loci

Indexed keywords

MICROSATELLITE DNA;

ANIMAL; ANIMAL DISEASE; ARTICLE; ATROPHIC RHINITIS; CHROMOSOME MAP; DISEASE RESISTANCE; FEMALE; GENETIC ASSOCIATION; GENETIC MARKER; GENETIC VARIABILITY; GENETICS; GENOTYPE; IMMUNOLOGY; MALE; MEAT; MYCOPLASMAL PNEUMONIA OF SWINE; QUANTITATIVE TRAIT LOCUS; RESPIRATORY TRACT DISEASE; SWINE; SWINE DISEASE;

ANIMALS; CHROMOSOME MAPPING; DISEASE RESISTANCE; FEMALE; GENETIC MARKERS; GENETIC VARIATION; GENOME-WIDE ASSOCIATION STUDY; GENOTYPE; MALE; MEAT; MICROSATELLITE REPEATS; PNEUMONIA OF SWINE, MYCOPLASMAL; QUANTITATIVE TRAIT LOCI; RESPIRATORY TRACT DISEASES; RHINITIS, ATROPHIC; SWINE; SWINE DISEASES;

ANIMALIA; MYCOPLASMA; SUIDAE; SUS SCROFA;

EID: 84867571142     PISSN: 02689146     EISSN: 13652052     Source Type: Journal    
DOI: 10.1111/j.1365-2052.2012.02359.x     Document Type: Article

References (40)

1. Almasy L., &, Blangero J., (1998) Multipoint quantitative-trait linkage analysis in general pedigrees. American Journal of Human Genetics 62, 1198-211. (Pubitemid 28199022)
2. Amos C.I., (1994) Robust variance-components approach for assessing genetic-linkage in pedigrees. American Journal of Human Genetics 54, 535-43. (Pubitemid 24068235)
3. Blangero J., Williams J.T., &, Almasy L., (2000) Robust LOD scores for variance component-based linkage analysis. Genetic Epidemiology 19, S8-14.
4. Davis A.E., Mejia P., &, Lu F.X., (2008) Biological activities of C1 inhibitor. Molecular Immunology 45, 4057-63.
5. Dèsautès C., Bidanel J.P., Milan D., Iannuccelli N., Amigues Y., Bourgeois F., Caritez J.C., Renard C., Chevalet C., &, Mormede P., (2002) Genetic linkage mapping of quantitative trait loci for behavioral and neuroendocrine stress response traits in pigs. Journal of Animal Science 80, 2276-85. (Pubitemid 41151676)
6. Djordjevic S.P., Eamens G.J., Romalis L.F., Nicholls P.J., Taylor V., &, Chin J., (1997) Serum and mucosal antibody responses and protection in pigs vaccinated against Mycoplasma hyopneumoniae with vaccines containing a denatured membrane antigen pool and adjuvant. Australian Veterinary Journal 75, 504-11.
7. Edfors-Lilja I., Wattrang E., Magnusson U., &, Fossum C., (1994) Genetic-variation in parameters reflecting immune competence of swine. Veterinary Immunology and Immunopathology 40, 1-16. (Pubitemid 24037451)
8. Edfors-Lilja I., Wattrang E., Marklund L., Moller M., Andersson-Eklund L., Andersson L., &, Fossum C., (1998) Mapping quantitative trait loci for immune capacity in the pig. Journal of Immunology 161, 829-35. (Pubitemid 28323547)
9. Edfors-Lilja I., Wattrang E., Andersson L., &, Fossum C., (2000) Mapping quantitative trait loci for stress induced alterations in porcine leukocyte numbers and functions. Animal Genetics 31, 186-93. (Pubitemid 30411248)
10. George A.W., Visscher P.M., &, Haley C.S., (2000) Mapping quantitative trait loci in complex pedigrees: a two-step variance component approach. Genetics 156, 2081-92. (Pubitemid 32001265)
11. Goddard M.E., Wray N.R., Verbyla K., &, Visscher P.M., (2009) Estimating effects and making predictions from genome-wide marker data. Statistical Science, 24, 517-29.
12. Gong Y.F., Lu X., Wang Z.P., et al,. (2010) Detection of quantitative trait loci affecting haematological traits in swine via genome scanning. BMC Genetics 11, 56.
13. Goodwin R.F.W., &, Whittles P., (1973) Enzootic pneumonia of pigs-immunization attempts inoculating mycoplasma-suipneumoniae antigen by various routes and with different adjuvants. British Veterinary Journal 129, 456-64.
14. Green P., Falls K., &, Crooks S., (1990) Documentation for cri-map, Version 2.4. Washington University School of Medicine, St Louis, MO.
15. Guyonnet-Duperat V., Geverink N., Plastow G.S., Evans G., Ousova O., Croisetiere C., Foury A., Richard E., Mormede P., &, Moisan M.P., (2006) Functional implication of an Arg307Gly substitution in corticosteroid-binding globulin, a candidate gene for a quantitative trait locus associated with cortisol variability and obesity in pig. Genetics 173, 2143-9. (Pubitemid 44285691)
16. Henryon M., Berg P., Christensen G., Jensen J., Lund M.S., &, Korsgaard I.R., (2003) Visual assessment of post-mortem lesions exhibits little additive genetic variation in growing pigs. Livestock Production Science 83, 121-30. (Pubitemid 37144293)
17. de Jong M.F,. (2006) Diseases of the respiratory system. In: Diseases of Swine, 9th edn (Ed. by, B.E. Straw, J.J. Zimmerman, S. D'Allaire, &, D.J. Taylor,), pp. 577-602. Blackwell, Ames, IA.
18. Kadowaki H., Suzuki E., Kojima-Shibata C., Suzuki K., Okamura T., Onodera W., Shibata T., &, Kano H,. (2012) Selection for resistance to swine mycoplasmal pneumonia over 5 generations in Landrace pigs. Livestock Science (in press).
19. Katayama M., Fukuda T., Okamura T., Suzuki E., Tamura K., Shimizu Y., Suda Y., &, Suzuki K., (2011) Effect of dietary addition of seaweed and licorice on the immune performance of pigs. Animal Science Journal 82, 274-81.
20. Lander E., &, Kruglyak L., (1995) Genetic dissection of complex traits-guidelines for interpreting and reporting linkage results. Nature Genetics 11, 241-7.
21. Lundeheim N., (1979) Genetic-analysis of respiratory-diseases in pigs. Acta Agriculturae Scandinavica 29, 209-15.
22. Lundeheim N., (1988) Health disorders and growth-performance at a Swedish pig progeny testing station. Acta Agriculturae Scandinavica 38, 77-88.
23. Magnusson U., &, Einarsson S., (1990) Effects of exogenous estradiol on the number and functional-capacity of circulating mononuclear and polymorphonuclear leukocytes in the sow. Veterinary Immunology and Immunopathology 25, 235-47. (Pubitemid 20246227)
24. Meuwissen T.H.E., &, Goddard M.E., (1996) The use of marker haplotypes in animal breeding schemes. Genetics Selection Evolution 28, 161-76. (Pubitemid 126633494)
25. Neumaier A., &, Groeneveld E., (1998) Restricted maximum likelihood estimation of covariances in sparse linear models. Genetics Selection Evolution 30, 3-26. (Pubitemid 28169219)
26. Niwa T., &, Nishida A,. (1994) Chapter 3: Genetics and breeding of pigs. In: The Handbook of Swine Husbandry (Ed. by, T. Niwa,), pp. 81-107. Yokendo, Tokyo, Japan (in Japanese).
27. Ousova O., Guyonnet-Duperat V., Iannuccelli N., et al,. (2004) Corticosteroid binding globulin: a new target for cortisol-driven obesity. Molecular Endocrinology 18, 1687-96. (Pubitemid 38859576)
28. Reiner G., Melchinger E., Kramarova M., Pfaff E., Buttner M., Saalmuller A., &, Geldermann H., (2002) Detection of quantitative trait loci for resistance/susceptibility to pseudorabies virus in swine. Journal of General Virology 83, 167-72. (Pubitemid 34030820)
29. Reiner G., Kliemt D., Willems H., et al,. (2007) Mapping of quantitative trait loci affecting resistance/susceptibility to Sarcocystis miescheriana in swine. Genomics 89, 638-46. (Pubitemid 46589948)
30. Reiner G., Fischer R., Hepp S., Berge T., Kohler F., &, Willems H., (2008) Quantitative trait loci for white blood cell numbers in swine. Animal Genetics 39, 163-8. (Pubitemid 351441686)
31. Slate J., Pemberton J.M., &, Visscher P.M., (1999) Power to detect QTL in a free-living polygynous population. Heredity 83, 327-36. (Pubitemid 29498803)
32. Sørensen V., Jorsal S.V., &, Mousing J,. (2006) Diseases of the respiratory system. In: Diseases of Swine, 9th edn (Ed. by, B.E. Straw, J. Zimmermann, S. D'Allaire, &, D.J. Taylor,), pp. 149-78. Iowa State University Press, Ames.
33. Thacker E.L,. (2006) Diseases of the respiratory system. In: Diseases of Swine, 9th edn (Ed. by, B.E. Straw, J.J. Zimmerman, S. D'Allaire, &, D.J. Taylor,), pp. 701-18. Blackwell, Ames, IA.
34. Uemoto Y., Nagamine Y., Kobayashi E., Sato S., Tayama T., Suda Y., Shibata T., &, Suzuki K., (2008) Quantitative trait loci analysis on Sus scrofa chromosome 7 for meat production, meat quality, and carcass traits within a Duroc purebred population. Journal of Animal Science 86, 2833-9.
35. Wagstrom E.A., Yoon K.J., &, Zimmerman J.J., (2000) Immune components in porcine mammary secretions. Viral Immunology 13, 383-97.
36. Wattrang E., Almqvist M., Johansson A., Fossum C., Wallgren P., Pielberg G., Andersson L., &, Edfors-Lilja I., (2005) Confirmation of QTL on porcine chromosomes 1 and 8 influencing leukocyte numbers, haematological parameters and leukocyte function. Animal Genetics 36, 337-45. (Pubitemid 41615472)
37. Williams J.T., Duggirala R., &, Blangero J., (1997) Statistical properties of a variance components method for quantitative trait linkage analysis in nuclear families and extended pedigrees. Genetic Epidemiology 14, 1065-70. (Pubitemid 28027534)
38. Wimmers K., Murani E., Schellander K., &, Ponsuksili S., (2009) QTL for traits related to humoral immune response estimated from data of a porcine F2 resource population. International Journal of Immunogenetics 36, 141-51.
39. Yamada Y., Yokouchi K., &, Nishida A., (1975) Selection index when genetic gains of individual traits are of primary concern. Japanese Journal of Genetics 50, 33-41.
40. Yang S., Ren J., Yan X., Huang X., Zou Z., Zhang Z., Yang B., &, Huang L., (2009) Quantitative trait loci for porcine white blood cells and platelet-related traits in a White Duroc x Erhualian F-2 resource population. Animal Genetics 40, 273-8.