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Volumn 51, Issue 8, 2012, Pages 996-1008

Interventions for alleviating cancer-related dyspnea: A systematic review and meta-analysis

Author keywords

[No Author keywords available]

Indexed keywords

FUROSEMIDE; HEMOGLOBIN; HYDROMORPHONE; MIDAZOLAM; MORPHINE; OXYGEN; PLACEBO;

EID: 84867554588     PISSN: 0284186X     EISSN: 1651226X     Source Type: Journal    
DOI: 10.3109/0284186X.2012.709638     Document Type: Review
Times cited : (71)

References (42)
  • 1
    • 0022628561 scopus 로고
    • Dyspnea in terminally ill cancer patients
    • Reuben D B, M or V. D yspnea in terminally ill cancer patients. Chest 1986; 89 : 234 - 6 .
    • (1986) Chest , vol.89 , pp. 234-236
    • Reuben, D.B.1    Mor, V.2
  • 2
    • 0028169032 scopus 로고
    • Chronic lung diseases and the perception of breathlessness: A clinical perspective
    • Burdon JG, P ain MC, R ubinfeld AR, N ana A. C hronic lung diseases and the perception of breathlessness: A clinical perspective. Eur Respir J 1994; 7 : 1342 - 9 .
    • (1994) Eur Respir J , vol.7 , pp. 1342-1349
    • Burdon, J.G.1    Pain, M.C.2    Rubinfeld, A.R.3    Nana, A.4
  • 3
    • 0033835416 scopus 로고    scopus 로고
    • The course of symptom frequency and intensity in advanced cancer patients followed at home
    • Mercadante S, C asuccio A, F ulfaro F. T he course of symptom frequency and intensity in advanced cancer patients followed at home. J Pain Symptom Manage 2000; 20 : 104 - 12 .
    • (2000) J Pain Symptom Manage , vol.20 , pp. 104-112
    • Mercadante, S.1    Casuccio, A.2    Fulfaro, F.3
  • 4
    • 0030917803 scopus 로고    scopus 로고
    • Disabling dyspnoea in patients with advanced disease: Lack of effect of nebulized morphine
    • Noseda A, C arpiaux JP, M arkstein C, M eyvaert A, d e Maertelaer V. Disabling dyspnoea in patients with advanced disease: Lack of effect of nebulized morphine. Eur Respir J 1997; 10 : 1079 - 83 .
    • (1997) Eur Respir J , vol.10 , pp. 1079-1083
    • Noseda, A.1    Carpiaux, J.P.2    Markstein, C.3    Meyvaert, A.4    De Maertelaer, V.5
  • 5
    • 33749865378 scopus 로고    scopus 로고
    • Dyspnea
    • Williams C M. D yspnea. C ancer J 2 006; 1 2: 3 65- 73.
    • (2006) Cancer J , vol.12 , pp. 365-373
    • Williams, C.M.1
  • 6
    • 20444485644 scopus 로고    scopus 로고
    • Nebulized versus subcutaneous morphine for patients with cancer dyspnea: A preliminary study
    • Bruera E, S ala R, S pruyt O, P almer JL, Z hang T, W illey J. Nebulized versus subcutaneous morphine for patients with cancer dyspnea: A preliminary study. J Pain Symptom Manage 2005; 29 : 613 - 8 .
    • (2005) J Pain Symptom Manage , vol.29 , pp. 613-618
    • Bruera, E.S.1    Ala, R.2    Spruyt, O.3    Palmer, J.L.4    Zhang, T.5    Willey, J.6
  • 7
    • 79952743028 scopus 로고    scopus 로고
    • Trajectory of performance status and symptom scores for patients with cancer during the last six months of life
    • Seow H, B arbera L, S utradhar R, H owell D, D udgeon D, Atzema C, et al. Trajectory of performance status and symptom scores for patients with cancer during the last six months of life. J Clin Oncol 2011; 29 : 1151 - 8 .
    • (2011) J Clin Oncol , vol.29 , pp. 1151-1158
    • Seow, H.1    Barbera, L.2    Sutradhar, R.3    Howell, D.4    Dudgeon, D.5    Atzema, C.6
  • 8
    • 0036845470 scopus 로고    scopus 로고
    • A systematic review of the use of opioids in the management of dyspnoea
    • Jennings AL, D avies AN, H iggins JP, G ibbs JS, B roadley KE. A systematic review of the use of opioids in the management of dyspnoea. Thorax 2002; 57 : 939 - 44 .
    • (2002) Thorax , vol.57 , pp. 939-944
    • Jennings, A.L.1    Davies, A.N.2    Higgins, J.P.3    Gibbs, J.S.4    Broadley, K.E.5
  • 9
    • 38549106194 scopus 로고    scopus 로고
    • Oxygen for relief of dyspnoea in mildly- or non-hypoxaemic patients with cancer: A systematic review and meta-analysis
    • Uronis HE, C urrow DC, M cCrory DC, S amsa GP, Abernethy AP. Oxygen for relief of dyspnoea in mildly- or non-hypoxaemic patients with cancer: A systematic review and meta-analysis. Br J Cancer 2008; 29 : 294 - 9 .
    • (2008) Br J Cancer , vol.29 , pp. 294-299
    • Uronis, H.E.1    Currow, D.C.2    McCrory, D.C.3    Samsa, G.P.4    Abernethy, A.P.5
  • 11
    • 44949240631 scopus 로고    scopus 로고
    • Nonpharmacological interventions for breathlessness in advanced stages of malignant and non-malignant diseases
    • Bausewein C, B ooth S, G ysels M, H igginson I. N onpharmacological interventions for breathlessness in advanced stages of malignant and non-malignant diseases. Cochrane Database Syst Rev 2008; 16; 2 .
    • (2008) Cochrane Database Syst Rev , vol.16 , pp. 2
    • Bausewein, C.1    Booth, S.2    Gysels, M.3    Higginson, I.4
  • 12
    • 85100415918 scopus 로고    scopus 로고
    • Cochrane handbook for system atic reviews of interventions version 5.0
    • cited 2011 Jul 30]. Available from
    • Higgins JPT, G reen S. C ochrane Handbook for System atic Reviews of Interventions Version 5.0. The Cochrane Collaboration; 2008 [cited 2011 Jul 30]. Available from: www.cochrane-handbook.org.
    • (2008) Cochrane Collaboration
    • Higgins, J.P.T.1    Green, S.2
  • 13
  • 14
    • 0033371696 scopus 로고    scopus 로고
    • The effects of morphine on dyspnea and ventilatory function in elderly patients with advanced cancer: A randomized doubleblind controlled trial
    • Mazzocato C, B uclin T, R apin CH. T he effects of morphine on dyspnea and ventilatory function in elderly patients with advanced cancer: A randomized doubleblind controlled trial. Ann Oncol 1999; 10 : 1511 - 4 .
    • (1999) Ann Oncol , vol.10 , pp. 1511-1514
    • Mazzocato, C.1    Buclin, T.2    Rapin, C.H.3
  • 16
    • 45849107938 scopus 로고    scopus 로고
    • Relief of incident dyspnea in palliative cancer patients: A pilot, randomized, controlled trial comparing nebulized hydromorphone, systemic hydromorphone, and nebulized saline
    • Charles MA, R eymond L, I srael F. R elief of incident dyspnea in palliative cancer patients: A pilot, randomized, controlled trial comparing nebulized hydromorphone, systemic hydromorphone, and nebulized saline. J Pain Symptom Manage 2008; 36 : 29 - 38 .
    • (2008) J Pain Symptom Manage , vol.36 , pp. 29-38
    • Charles, M.A.1    Reymond, L.2    Israel, F.3
  • 17
    • 62449095978 scopus 로고    scopus 로고
    • Use of oxygen and opioids in the palliation of dyspnea in hypoxic and non-hypoxic palliative care patients: A prospective study
    • Clemens K E, Q uednau I, K laschik E. U se of oxygen and opioids in the palliation of dyspnea in hypoxic and non-hypoxic palliative care patients: A prospective study. Support Care Cancer 2009; 17 : 367-377
    • (2009) Support Care Cancer , vol.17 , pp. 367-377
    • Clemens, K.E.Q.1    Uednau, I.K.2    Laschik, E.3
  • 18
    • 0002295470 scopus 로고    scopus 로고
    • Single dose randomized controlled trial of nebulised morphine in patients with cancer related breathlessness
    • Davis C, Penn K A 'H ern R, D aniels J, S levin M. S ingle dose randomized controlled trial of nebulised morphine in patients with cancer related breathlessness. Palliat Med 1996; 10 : 64 - 5 .
    • (1996) Palliat Med , vol.10 , pp. 64-65
    • Davis, C.1    Penn, K.A.2    Hern, R.3    Daniels, J.4    Slevin, M.5
  • 20
    • 0032926438 scopus 로고    scopus 로고
    • How effective are supplementary doses of opioids for dyspnea in terminally ill cancer patients? A randomized continuous sequential clinical trial
    • Allard P, L amontagne C, B ernard P, T remblay C. H ow effective are supplementary doses of opioids for dyspnea in terminally ill cancer patients? A randomized continuous sequential clinical trial. J Pain Symptom Manage 1999; 17 : 256 - 65 .
    • (1999) J Pain Symptom Manage , vol.17 , pp. 256-265
    • Allard, P.1    Lamontagne, C.2    Bernard, P.3    Tremblay, C.4
  • 21
    • 77956359074 scopus 로고    scopus 로고
    • Effect of palliative oxygen versus room air in relief of breathlessness in patients with refractory dyspnoea: A double-blind, randomised controlled trial
    • Abernethy AP, M cDonald C F, F rith P A, C lark K, Herndon JE 2nd, Marcello J. Effect of palliative oxygen versus room air in relief of breathlessness in patients with refractory dyspnoea: A double-blind, randomised controlled trial. Lancet 2010; 376 : 784 - 93 .
    • (2010) Lancet , vol.376 , pp. 784-793
    • Abernethy, A.P.1    McDonald, C.F.2    Frith, P.A.3    Clark, K.4    Herndon, I.I.J.E.5    Marcello, J.6
  • 22
    • 33845348210 scopus 로고    scopus 로고
    • A randomized, double-blind, crossover trial of the effect of oxygen on dyspnea in patients with advanced cancer
    • Philip J, G old M, M ilner A, D i Iulio J, M iller B, S pruyt O. A randomized, double-blind, crossover trial of the effect of oxygen on dyspnea in patients with advanced cancer. J Pain Symptom Manage 2006; 32 : 541 - 50 .
    • (2006) J Pain Symptom Manage , vol.32 , pp. 541-550
    • Philip, J.1    Gold, M.2    Milner, A.3    Diiulio, J.4    Miller, B.5    Spruyt, O.6
  • 23
    • 0344668700 scopus 로고    scopus 로고
    • A randomized controlled trial of supplemental oxygen versus air in cancer patients with dyspnea
    • Bruera E, S weeney C, W illey J, P almer JL, S trasser F, Morice RC, et al. A randomized controlled trial of supplemental oxygen versus air in cancer patients with dyspnea. Palliat Med 2003; 17 : 659 - 63 .
    • (2003) Palliat Med , vol.17 , pp. 659-663
    • Bruera, E.1    Sweeney, C.2    Willey, J.3    Palmer, J.L.4    Strasser, F.5    Morice, R.C.6
  • 25
  • 26
    • 1342344003 scopus 로고    scopus 로고
    • A double-blind, randomised, controlled phase II trial of Heliox28 gas mixture in lung cancer patients with dyspnoea on exertion
    • Ahmedzai S H, L aude E, R obertson A, T roy G, V ora V. A double-blind, randomised, controlled phase II trial of Heliox28 gas mixture in lung cancer patients with dyspnoea on exertion. Br J Cancer 2004; 90 : 366 - 71 .
    • (2004) Br J Cancer , vol.90 , pp. 366-371
    • Ahmedzai, S.H.1    Laude, E.2    Robertson, A.3    Troy, G.4    Vora, V.5
  • 27
    • 31344456197 scopus 로고    scopus 로고
    • Midazolam as adjunct therapy to morphine in the alleviation of severe dyspnea perception in patients with advanced cancer
    • Navigante A H, C erchietti LC, C astro MA, L utteral MA, Cabalar ME. Midazolam as adjunct therapy to morphine in the alleviation of severe dyspnea perception in patients with advanced cancer. J Pain Symptom Manage 2006; 31 : 38 - 47 .
    • (2006) J Pain Symptom Manage , vol.31 , pp. 38-47
    • Navigante, A.H.1    Cerchietti, L.C.2    Castro, M.A.3    Lutteral, M.A.4    Cabalar, M.E.5
  • 28
    • 77952299580 scopus 로고    scopus 로고
    • Morphine versus midazolam as upfront therapy to control dyspnea perception in cancer patients while its underlying cause is sought or treated
    • Navigante AH, C astro M A, C erchietti L C. M orphine versus midazolam as upfront therapy to control dyspnea perception in cancer patients while its underlying cause is sought or treated. J Pain Symptom Manage 2010; 39 : 820 - 30 .
    • (2010) J Pain Symptom Manage , vol.39 , pp. 820-830
    • Navigante, A.H.1    Castro, M.A.2    Cerchietti, L.C.3
  • 29
    • 53649105123 scopus 로고    scopus 로고
    • Randomised, placebo controlled trial of nebulised furosemide for breathlessness in patients with cancer
    • Wilcock A, W alton A, M anderson C, F eathers L, El Khoury B, Lewis M, et al. Randomised, placebo controlled trial of nebulised furosemide for breathlessness in patients with cancer. Thorax 2008; 63 : 872 - 5 .
    • (2008) Thorax , vol.63 , pp. 872-875
    • Wilcock, A.1    Walton, A.2    Manderson, C.3    Feathers, L.4    El Khoury, B.5    Lewis, M.6
  • 31
    • 0022312957 scopus 로고
    • A merican opiophobia: Customary underutilisation of opioid analgesics
    • Morgan JP. A merican opiophobia: Customary underutilisation of opioid analgesics. Adv Alcohol Subst Abuse 1985; 5 : 163 - 73 .
    • (1985) Adv Alcohol Subst Abuse , vol.5 , pp. 163-173
    • Morgan, J.P.1
  • 32
    • 0033197984 scopus 로고    scopus 로고
    • HIgh dose morphine use in the hospice setting: A database survey of patient characteristics and effect on life expectancy
    • Bercovitch M, W aller A, A dunsky A. H igh dose morphine use in the hospice setting: A database survey of patient characteristics and effect on life expectancy. Cancer 1999; 86 : 871 - 7 .
    • (1999) Cancer , vol.86 , pp. 871-877
    • Bercovitch, M.W.1    Aller, A.A.2    Dunsky, A.3
  • 33
    • 0032111417 scopus 로고    scopus 로고
    • A prospective study on the dying process in terminally ill cancer patients
    • Morita T, I chiki T, T sunoda J, I noue S, C hihara S. A prospective study on the dying process in terminally ill cancer patients. Am J Hosp Palliat Care 1998; 15 : 217 - 22 .
    • (1998) Am J Hosp Palliat Care , vol.15 , pp. 217-222
    • Morita, T.1    Ichiki, T.2    Tsunoda, J.3    Inoue, S.4    Chihara, S.5
  • 34
    • 0035054798 scopus 로고    scopus 로고
    • Effects of high dose opioids and sedatives on survival in terminally ill cancer patients
    • Morita T, T sunoda J, I noue S, C hihara S. E ffects of high dose opioids and sedatives on survival in terminally ill cancer patients. J Pain Symptom Manage 2001; 21 : 282 - 9 .
    • (2001) J Pain Symptom Manage , vol.21 , pp. 282-289
    • Morita, T.1    Tsunoda, J.2    Inoue, S.3    Chihara, S.4
  • 35
    • 0025885805 scopus 로고
    • Validation of world health organisation guidelines for cancer pain relief during the last days and hours of life
    • Grond S, Z ech D, S chug S A, L ynch J, L ehmann K A. V alidation of World Health Organisation guidelines for cancer pain relief during the last days and hours of life. J Pain Symptom Manage 1991; 6 : 411 - 22 .
    • (1991) J Pain Symptom Manage , vol.6 , pp. 411-422
    • Grond, S.1    Zech, D.2    Schug, S.A.3    Lynch, J.4    Lehmann, K.A.5
  • 36
    • 0034729998 scopus 로고    scopus 로고
    • Opioid use in the last week of life and implications for end of life decision-making
    • Thorns A, S ykes N. O pioid use in the last week of life and implications for end of life decision-making. Lancet 2000; 356 : 398 - 9 .
    • (2000) Lancet , vol.356 , pp. 398-399
    • Thorns, A.1    Sykes, N.2
  • 37
    • 0037716612 scopus 로고    scopus 로고
    • The use of opioids and sedatives at the end of life
    • Sykes N, T horns A. T he use of opioids and sedatives at the end of life. Lancet Oncol 2003; 4 : 312 - 8 .
    • (2003) Lancet Oncol , vol.4 , pp. 312-318
    • Sykes, N.1    Thorns, A.2
  • 38
    • 0042377298 scopus 로고    scopus 로고
    • Randomised, double blind, placebo controlled crossover trial of sustained release morphine for the management of refractory dyspnoea
    • A bernethy AP, C urrow DC, F rith P, F azekas BS, M cHugh A, Bui C. Randomised, double blind, placebo controlled crossover trial of sustained release morphine for the management of refractory dyspnoea. BMJ 2003; 327 : 523 - 8 .
    • (2003) BMJ , vol.327 , pp. 523-528
    • Abernethy, A.P.1    Currow, D.C.2    Frith, P.3    Fazekas, B.S.4    McHugh, A.5    Bui, C.6
  • 39
    • 0029786583 scopus 로고    scopus 로고
    • Dyspnea in cancer patients etiology, resource utilization, and survival-implications in a managed care world
    • Escalante C P, M artin C G, E lting L S, C antor S B, H arle TS, Price KJ, et al. Dyspnea in cancer patients. Etiology, resource utilization, and survival-implications in a managed care world. Cancer 1996; 78 : 1314 - 9 .
    • (1996) Cancer , vol.78 , pp. 1314-1319
    • Escalante, C.P.1    Martin, C.G.2    Elting, L.S.3    Cantor, S.B.4    Harle, T.S.5    Price, K.J.6
  • 41
  • 42
    • 58849154045 scopus 로고    scopus 로고
    • Characteristics and correlates of dyspnea in patients with advanced cancer
    • Reddy SK, P arsons HA, E lsayem A, P almer JL, B ruera E. Characteristics and correlates of dyspnea in patients with advanced cancer. J Palliat Med 2009; 12 : 29 - 36 .
    • (2009) J Palliat Med , vol.12 , pp. 29-36
    • Reddy, S.K.1    Parsons, H.A.2    Elsayem, A.3    Palmer, J.L.4    Bruera, E.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.