Interleukin 1-beta upregulates brain-derived neurotrophic factor, neurotrophin 3 and neuropilin 2 gene expression and NGF production in annulus cells

Biotechnic and Histochemistry

Volumn 87, Issue 8, 2012, Pages 506-511

  Gruber, H E ^a   Hoelscher, G L ^a   Bethea, S ^a   Hanley, E N ^a  

^a CAROLINAS MEDICAL CENTER   (United States)

Author keywords

IL 1 ; Intervertebral disc; Nerve growth factor; Neurotrophins; Tissue culture

Indexed keywords

EID: 84867530353     PISSN: 10520295     EISSN: 14737760     Source Type: Journal    
DOI: 10.3109/10520295.2012.703692     Document Type: Article

References (42)

1. Abe Y, Akeda K, An HS, Aoki Y, Pichika R, Muehleman C, Kimura T, Masuda K (2007) Proinflammatory cytokines stimulate the expression of nerve growth factor by human intervertebral disc cells. Spine 32: 635-642. (Pubitemid 46573301)
2. Akyol S, Senel Eraslan B, Etyemez H, Tanriverdi T, Hanci M (2010) Catabolic cytokine expressions in patients with degenerative disc disease. Turk. Neurosurg. 20: 492-499.
3. Aoki Y, Ohtori S, Takahashi K, Ino H, Takahashi Y, Chiba T, Moriya H (2004) Innervation of the lumbar intervertebral disc by nerve growth factor-dependent neurons related to inflammatory pain. Spine 29: 1077-1081. (Pubitemid 38649820)
4. Bennett JH (2001) Neurotrophic factors: important regulators of nociceptive function. Neuroscientist 7: 13-17.
5. Dyck PJ, Peroutka S, Rask C, Burton E, Baker MK, Lehman LA, Gillen DA, Hokanson JL, O'Brien PC (1997) Intradermal recombinant human nerve growth factor induces pressure allodynia and lowered heatpain threshold in humans. Neurology 48: 501-505. (Pubitemid 27087628)
6. Fernandez-Fernandez MF, Veprintsev DB, Fersht AR (2005) Proteins of the S100 family regulate the oligomerization of p53 tumor suppressor. Proc. Natl. Acad. Sci. USA 102: 4735-4740. (Pubitemid 40471523)
7. Freemont AJ, Watkins A, LeMaitre C, Baird P, Jeziorska M, Knight MTN, Ross ERS, O'Brien JP, Hoyland JA (2002a) Nerve growth factor expression and innervation of the painful intervertebral disc. J. Pathol. 197: 286-292. (Pubitemid 34778297)
8. Freemont AJ, Watkins A, LeMaitre C, Jeziorska M, Hoyland JA (2002b) Current understanding of cellular and molecular events in intervertebral disc degeneration: implications for therapy. J. Pathol. 196: 374-379. (Pubitemid 34262847)
9. Garcia-Cosamalon J, del Valle ME, Calavia MG, Garcia-Suarez O, Lopez-Muniz A, Otero J, Vega JA (2010) Intervertebral disc, sensory nerves and neurotrophins: who is who in discogenic pain? J. Anat. 217: 1-15.
10. Gigante A, Bevilacqua C, Pagnotta A, Manzotti S, Toesca A, Greco F (2003) Expression of NGF, Trka and p75 in human cartilage. Eur. J. Histochem. 47: 339-344. (Pubitemid 38029613)
11. Gruber HE, Fisher EC Jr, Desai B, Stasky AA, Hoelscher G, Hanley EN (1997) Human intervertebral disc cells from the annulus: three-dimensional culture in agarose or alginate and responsiveness to TGF-β1. Exp. Cell Res. 235: 13-21. (Pubitemid 27381676)
12. Gruber HE, Hoelscher GL, Deepe R, Hanley EN Jr (2010) IL-1 and TNF - a stimulate pregnancy-associated plasma protein A production in human annulus cells in three-dimensional culture. Orthopaedic Research Society Annual Meeting, poster no. 1420.
13. Gruber HE, Hoelscher GL, Leslie K, Ingram JA, Hanley EN Jr (2006) Three-dimensional culture of human disc cells within agarose or a collagen sponge: assessment of proteoglycan production. Biomaterials 27: 371-376. (Pubitemid 41457240)
14. Gruber HE, Ingram JA, Hoelscher G, Zinchenko N, Norton HJ, Hanley EN Jr (2008) Brain-derived neurotrophic factor and its receptor in the human and the sand rat intervertebral disc. Biomed. Cent. Arthr. Res. Ther. 10: R82.
15. Hoyland JA, Le Maitre C, Freemont AJ (2008) Investigation of the role of IL-1 and TNF in matrix degradation in the intervertebral disc. Rheumatology 47: 809-814. (Pubitemid 351796365)
16. Iannone F, De Bari C, Dell'Accio F, Covelli M, Patella V, Lo Bianco G, Lapadula G (2002) Increased expression of nerve growth factor (NGF) and high affinity NGF receptor (p140 TrkA) in human osteoarthritic chondrocytes. Rheumatology (Oxford) 41: 1413-1418. (Pubitemid 36004319)
17. Jones KR, Reichardt LF (1990) Molecular cloning of a human gene that is a member of the nerve growth factor family. Proc. Natl. Acad. Sci. USA 87: 8060-8064.
18. Kalcheim C, Carmeli C, Rosenthal A (1992) Neurotrophin 3 is a mitogen for cultured neural crest cells. Proc. Natl. Acad. Sci. USA 89: 1661-1665.
19. Kidd T, Brose K, Mitchell KJ, Fetter RD, Tessier-Lavigne M, Goodman CS, Tear G (1998) Roundabout controls axon crossing of the CNS midline and defines a novel subfamily of evolutionarily conserved guidance receptors. Cell 92: 205-215. (Pubitemid 28073044)
20. RB and is involved in neuronal differentiation. J. Cell Biol. 141: 553-566. (Pubitemid 28217904)
21. Kolodkin AL, Levengood DV, Rowe EG, Tai Y-T, Giger RJ, Ginty DD (1997) Neuropilin is a semaphorin III receptor. Cell 90: 753-762. (Pubitemid 27357966)
22. Kolomeyer AM, Sugino IK, Zarbin MA (2011) Characterization of conditioned media collected from cultured adult versus fetal retinal pigment epithelial cells. Invest. Ophthalmol. Vis. Sci. 52: 5973-5986.
23. Kuruvilla R, Zweifel LS, Glebova NO, Lonze BE, Valdez G, Ye H, Ginty DD (2004) A neurotrophin signaling cascade coordinates sympathetic neuron development through differnetial control of TrkA trafficking and retrograde signaling. Cell 118: 243-255. (Pubitemid 38962579)
24. Lee JM, Song JY, Baek M, Jung H-Y, Kang H, Han IB, Kwon YD, Shin DE (2011) Interleukin-1β induces angiogenesis and innervation in human intervertebral disc degeneration. J. Orthop. Res. 29: 265-269.
25. LeMaitre CL, Freemont AJ, Hoyland JA (2005) The role of interleukin-1 in the pathogenesis of human intervertebral disc degeneration. Arthr. Res. Ther. 7: R732-R745.
26. LeMaitre CL, Hoyland JA, Freemont AJ (2007) Catabolic cytokine expression in degenerate and herniated human intervertebral discs: IL-1 β and TNFa expression profile. Arthr. Res. Ther. http://arthritis-research.com/content/9/4/ R77
27. McHugh JM, McHugh WB (2000) Pain: neuroanatomy, chemical mediators, and clinical implications. AACN Clin. Issues Adv. Pract. Acute Crit. Care 11: 168-178.
28. Mendell LM, Albers KM, Davis BM (1999) Neurotrophins, nociceptors, and pain. Microsc. Res. Tech. 45: 252-261. (Pubitemid 29264989)
29. Millward-Sadler SJ, Costello PW, Freemont AJ, Hoyland JA (2009) Regulation of catabolic gene expression in normal and degenerate human intervertebral disc cells: implications for the pathogenesis of intervertebral disc degeneration. Arthr. Res. Ther. 11: R65.
30. Ming M, Li X, Fan X, Yang D, Li L, Chen S, Gu Q, Le W (2009) Retinal pigment epithelial cells secrete neurotrophic factors and synthesize dopamine: possible contribution to therapeutic effects of RPE cell transplantation in Parkinson's disease. J. Trans. Med. 7: 53.
31. Oinuma I, Ishikawa Y, Katoh H, Negishi M (2004) The semaphorin 4D receptor plexin-B1 is a GTPase activating protein for R-Ras. Science 305: 862-865. (Pubitemid 39038420)
32. Pagnotta A, Tos P, Fornaro M, Gigante A, Geuna S, Battiston B (2002) Neurotrophins and their receptors in early axonal regeneration along muscle-vein-combined grafts. Microsurgery 22: 300-303. (Pubitemid 35231871)
33. Purmessur D, Freemont AJ, Hoyland JA (2008) Expression and regulation of neurotrophins in the nondegenerate and degenerate human intervertebral disc. Arthr. Res. Ther. 10: R.
34. Rand N, Juliao SF, Floman Y, Spengler DM (1998) Cultured human intervertebral disc cells secrete interleukin-6. Internatl. Soc. Study Lumbar Spine, 1998 Annual Meeting, abstract #180.
35. Rand N, Reichert F, Floman Y, Rotshenker S (1997) Murine nucleus pulposus-derived cells secrete interleukins-1-β, -6, and -10 and granulocyte-macrophage colonystimulating factor in cell culture. Spine 22: 2598-2601.
36. Sommer C, Kress M (2004) Recent findings on how proinflammatory cytokines cause pain: peripheral mechanisms in inflammatory and neuropathic hyperalgesia. Neurosci. Lett. 361: 184-187. (Pubitemid 38609247)
37. Tessier-Lavigne M, Goodman CS (1996) The molecular biology of axon guidance. Science 274: 1123-1133. (Pubitemid 26389268)
38. The Gene Ontology Consortium (2000) Gene ontology: tool for the unification of biology. Nat. Genet. 25: 25-29.
39. Thompson JP, Pearce RH, Schechter MT, Adams ME, Tsang IKY, Bishop PB (1990) Preliminary evaluation of a scheme for grading the gross morphology of the human intervertebral disc. Spine 15: 411-415. (Pubitemid 20188043)
40. Tolofari SK, Richardson SM, Freemont AJ, Hoyland JA (2010) Expression of semaphorin 3A and its receptors in the human intervertebral disc: potential role in regulating neural ingrowth in the degenerate intervertebral disc. Arthr. Res. Ther. 12: R1.
41. Vilar M, Murillo-Carretero M, Mira H, Magnusson K, Besset V, Ibanez CF (2006) BEX1, a novel interactor of the p75 neurotrophin receptor, links neurotrophin signaling to the cell cycle. EMBO J. 25: 1219-1230.
42. Wainwright MS, Cfart JM, Griffn WST, Marks A, Pineda J, Padgett KR, Van Eldik LJ (2004) Increased susceptibility of S100B transgenic mice to perinatal hypoxia-ischemia. Ann. Neurol. 56: 62-67.