Development of a TaqMan multiplex PCR assay for detection of plasmid-mediated AmpC β-lactamase genes

Journal of Clinical Microbiology

Volumn 50, Issue 11, 2012, Pages 3722-3725

  Geyer, Chelsie N ^a   Reisbig, Mark D ^a   Hanson, Nancy D ^a  

^a CREIGHTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA LACTAM ANTIBIOTIC; BETA LACTAMASE AMPC; CEPHALOSPORIN DERIVATIVE; CEPHAMYCIN DERIVATIVE; MONOBACTAM DERIVATIVE; PENICILLIN DERIVATIVE;

AEROMONAS HYDROPHILA; AEROMONAS SOBRIA; AMPC GENE; ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIAL GENE; CITROBACTER FREUNDII; CONTROLLED STUDY; ENTEROBACTER CLOACAE; ESCHERICHIA COLI; GENE AMPLIFICATION; GRAM NEGATIVE BACTERIUM; HAFNIA ALVEI; KLEBSIELLA PNEUMONIAE; MORGANELLA MORGANII; MULTIPLEX POLYMERASE CHAIN REACTION; NONHUMAN; NUCLEOTIDE SEQUENCE; PLASMID; PRIORITY JOURNAL; SALMONELLA;

BACTERIAL PROTEINS; BACTERIOLOGICAL TECHNIQUES; BETA-LACTAMASES; ENTEROBACTERIACEAE; ENTEROBACTERIACEAE INFECTIONS; HUMANS; MULTIPLEX POLYMERASE CHAIN REACTION; PLASMIDS; REAL-TIME POLYMERASE CHAIN REACTION; SENSITIVITY AND SPECIFICITY;

EID: 84867521186     PISSN: 00951137     EISSN: 1098660X     Source Type: Journal    
DOI: 10.1128/JCM.02038-12     Document Type: Article

References (17)

1. Bauernfeind A, Chong Y, Lee K. 1998. Plasmid-encoded AmpC beta-lactamases: how far have we gone 10 years after the discovery? Yonsei Med. J. 39:520 -525.
2. Black JA, Moland ES, Thomson KS. 2005. AmpC disk test for the detection of plasmid-mediated AmpC beta-lactamases in Enterobacteriaceae lacking chromosomal AmpC beta-lactamases. J. Clin. Microbiol. 43:3110-3113. (Pubitemid 40981309)
3. Bradford P, et al. 1997. Imipenem resistance in Klebsiella pneumoniae is associated with the combination of ACT-1, a plasmid-mediated AmpC β-lactamase, and the loss of an outer membrane protein. Antimicrob. Agents Chemother. 41:563-569. (Pubitemid 27098404)
4. Coudron P. 2005. Inhibitor-based methods for detection of plasmid-mediated AmpC β-lactamases in Klebsiella spp., Escherichia coli, and Proteus mirabilis. J. Clin. Microbiol. 43:4163-4167. (Pubitemid 41129715)
5. Coudron P, Moland ES, Thomson KS. 2000. Occurrence and detection of AmpC beta-lactamases among Escherichia coli, Klebsiella pneumoniae, and Proteus mirabilis isolates at a veterans medical center. J. Clin. Microbiol. 38:1791-1795.
6. Elemam A, Rahimian J, Mandell W. 2009. Infection with panresistant Klebsiella pneumoniae: a report of 2 cases and a brief review of the literature. Clin. Infect. Dis. 49:271-274.
7. Hanson ND, Sanders CC. 1999. Regulation of inducible AmpC beta-lactamase expression among Enterobacteriaceae. Curr. Pharm. Des. 5:881-894.
8. Hemalatha V, Padma M, Uma Sekar Vinodh TM, Arunkumar AS. 2007. Detection of AmpC beta lactamases production in Escherichia coli and Klebsiella by an inhibitor based method. Indian J. Med. Res. 126:220-223.
9. Jacoby GA. 2009. AmpC β-lactamases. Clin. Microbiol. Rev. 22:161-182.
10. Kang CI, et al. 2004. Cefepime and the inoculum effect in tests with Klebsiella pneumoniae producing plasmid-mediated AmpC-type β-lactamase. J. Antimicrob. Chemother. 54:1130-1133.
11. Netzel TC, et al. 2007. The AmpC inhibitor, Syn2190, can be used to reveal extended-spectrum β-lactamases in Escherichia coli. Diagn. Microbiol. Infect. Dis. 58:345-348. (Pubitemid 47017639)
12. Owens RC, Jr, et al. 2011. Community transmission in the United States of a CTX-M-15 producing sequence type ST131 Escherichia coli strain resulting in death. J. Clin. Microbiol. 49:3406-3408.
13. Pai H, et al. 2004. Epidemiology and clinical features of bloodstream infections caused by AmpC-type beta-lactamase-producing Klebsiella pneumoniae. Antimicrob. Agents Chemother. 48:3720-3728. (Pubitemid 39304595)
14. Park YS, et al. 2009. Risk factors and clinical features of infections caused by plasmid-mediated AmpC beta-lactamase-producing Enterobacteriaceae. Int. J. Antimicrob. Agents 34:38-43.
15. Perez-Perez FJ, Hanson ND. 2002. Detection of plasmid-mediated AmpC β-lactamase genes in clinical isolates by using multiplex PCR. J. Clin. Microbiol. 40:2153-2162. (Pubitemid 34596400)
16. Rand KH, et al. 2011. Clinical detection of AmpC β-lactamase: does it affect patient outcome? Am. J. Clin. Pathol. 135:572-576.
17. Tenover et al. 2009. Identification of plasmid-mediated AmpC beta-lactamases in Escherichia coli, Klebsiella spp., and Proteus species can potentially improve reporting of cephalosporin susceptibility testing results. J. Clin. Microbiol. 47:294 -299.