Plasmid-encoded AmpC β-lactamases: How far have we gone 10 years after the discovery?

Yonsei Medical Journal

Volumn 39, Issue 6, 1998, Pages 520-525

  Bauernfeind, Adolf ^a   Chong, Yunsop ^b   Lee, Kyungwon ^b  

^a UNIVERSITY OF MUNICH   (Germany)

^b Yonsei University College of Medicine   (South Korea)

Author keywords

AmpC lactamases; CMY 1; CMY 2; Molecular evolution of lactamases; Plasmid encoded lactamases

Indexed keywords

BETA LACTAM ANTIBIOTIC; BETA LACTAMASE;

AMINO ACID SUBSTITUTION; ANTIBIOTIC RESISTANCE; BACTERIAL GENE; CITROBACTER FREUNDII; GENE CLUSTER; GENE LOCATION; NONHUMAN; REVIEW;

EID: 0032450190     PISSN: 05135796     EISSN: None     Source Type: Journal    
DOI: 10.3349/ymj.1998.39.6.520     Document Type: Review

References (23)

1. Barnaud O, Arlet G, Danglot C, Philippon A: Cloning and sequencing of the gene encoding the AmpC β-lactamase of Morganella morganii. FEMS Microbiol Lett 148: 15-20, 1997
2. Barnaud G, Arlet G, Verdet C, Gaillot O, Lagrange PH, Philippon A: Salmonella enteritidis: AmpC plasmid-mediated inducible β-lactamase (DHA-1) with an ampR gene from Morganella morganii. Antimicrob Agents Chemother 42: 2352-2358, 1998
3. Bauernfeind A, Chong Y, Schweighart S: Extended broad spectrum β-lactamase in Klebsiella pneumoniae including resistance to cephamycins. Infection 17: 316-321, 1989
4. Bauernfeind A, Schneider I, Jungwirth R, Sahly H, Ullmann U: A novel type of AmpC β-lactamase, ACC-1, produced by a Klebsiella pneumoniae causing nosocomial pneumonia. Antimicrob Agents Chemother (submitted), 1998
5. Bauernfeind A, Schneider I, Meyer D, Jungwirth R, Chong Y, Lee K: Possible role of amino acid substitution at position 346 on the ceftazidime-hydrolyzing activity of the cephamycinase CMY-1, abstr. C203. In Abstracts of the 37th Interscience Conference on Antimicrobial Agents and Chemotherapy. Washington D.C., American Society for Microbiology, 1997a, 80
6. Bauernfeind A, Stemplinger I, Jungwirth R, Giamarellou H: Characterization of the plasmidic β-lactamase CMY-2, which is responsible for cephamycin resistance. Antimicrob Agents Chemother 40: 221-224, 1996
7. Bauernfeind A, Wagner S, Jungwirth R, Schneider I, Meyer D: A novel class C β-lactamase (FOX-2) in Escherichia coli conferring resistance to cephamycins. Antimicrob Agents Chemother 41: 2041-2046, 1997b
8. Boyer-Mariotte S, Raskine L, Hanau B, Philippon A, Sanson-Le Pors MJ, Arlet G: Novel plasmid-mediated AmpC-type β-lactamase (MOX-2) in a clinical isolate of Klebsiella pneumoniae, abstr. C7. In Abstracts of the 38th Interscience Conference on Antimicrobial Agents and Chemotherapy. Washington D.C., American Society for Microbiology, 1998, 70
9. Bradford PA, Urban C, Mariano N, Projan SJ, Rahal JJ, Bush K: Imipenem resistance in Klebsiella pneumoniae is associated with the combination of ACT-1, a plasmid-mediated AmpC β-lactamase, and the loss of an outer membrane protein. Antimicrob Agents Chemother 41: 563-569, 1997
10. Bret L, Chanal-Claris C, Sirot D, Chaibi EB, Labia R, Sirot I: Chromosomally encoded AmpC-type β-lactamase in a clinical isolates of Proteus mirabilis. Antimicrob Agents Chemother 42: 1110-1114, 1998
11. BIL-1, a plasmid-mediated class C β-lactamase gene in Escherichia coli BS. Antimicrob Agents Chemother 38: 1182-1185, 1994
12. Galleni M, Lindberg F, Normark S, Cole S, Honore N, Joris B, Frere J-M: Sequence analysis of three Enterobacter cloacae ampC β-lactamase genes and their products. J Biochem 250: 753-760, 1988
13. Gazouli M, Tzouvelekis LS, Prinarakis E, Miriagou V, Tzelepi E: Transferable cefoxitin resistance in enterobacteria from Greek hospitals and characterization of a plasmid-mediated group 1 β-lactamase (LAT-2). Antimicrob Agents Chemother 40: 1736-1740, 1996
14. Gazouli M, Tzouvelekis LS, Vatopoulos AC, Tzelepi E: Transferable class C β-lactamase in Escherichia coli strains isolated in Greek hospitals and characterization of two enzyme variants (LAT-3 and LAT-4) closely related to Citrobacter freundii AmpC β-lactamase. J Antimicrob Chemother (submitted), 1998
15. Gonzalez Leiza M, Perez-Diaz JC, Ayala J, Casellas JM, Martinez-Beltran J, Bush K, Baquero F: Gene sequence and biochemical characterization of FOX-1 from Klebsiella pneumoniae, a new AmpC-type plasmid-mediated β-lactamase with two molecular variants. Antimicrob Agents Chemother 38: 2150-2157, 1994
16. MOX-1 gene encoding AmpC-type β-lactamase. Gene 139: 93-98, 1994
17. Lindberg F, Normark S: Sequence of the Citrobacter freundii OS60 chromosomal ampC β-lactamase gene. Eur J Biochem 156: 441-445, 1986
18. Lodge JM, Minchin SD, Piddock LJV, Busby SJW: Cloning, sequencing and analysis of the structural gene and regulatory region of the Pseudomonas aeruginosa chromosomal AmpC β-lactamase. Biochem J 272: 627-631, 1990
19. Marchese A, Ariel G, Schito GC, Lagrange PH, Philippon A: Characterization of FOX-3, an AmpC-type plasmid-mediated β-lactamase from an Italian isolate of Klebsiella oxytoca. Antimicrob Agents Chemother 42: 464-467, 1998
20. Nomura K, Yoshida T: Nucleotide sequence of the Serratia marcescens SR50 chromosomal ampC β-lactamase gene. FEMS Microbiol Lett 70: 295-300, 1990
21. Papanicolau GA, Medeiros AA, Jacoby GA: Novel plasmid-mediated β-lactamase (MLR-1) conferring resistance to oxyimino-and a-methoxy β-lactams in clinical isolates of Klebsiella pneumoniae. Antimicrob Agents Chemother 34: 2200-2209, 1990
22. Seoane A, Francia MV, Garcia Lobo JM: Nucleotide sequence of the ampC-ampR region from the chromosome of Yersinia enterocolitica. Antimicrob Agents Chemother 36: 1049-1052, 1992
23. Tzouvelekis LS, Tzelepi E, Mentis AF, Tsakaris A: Identification of a novel plasmid-mediated β-lactamase with chromosomal cephalosporinase characteristics from Klebsiella pneumoniae. J Antimicrob Chemother 31: 645-654, 1993