Observation on anticancer function of PS II isolated from rhizoma paridis

Journal of Sichuan University (Medical Science)

Volumn 43, Issue 5, 2012, Pages 651-656

  Xiao, Xue ^a   Yang, Mei ^a   Bai, Peng ^a   Chen, Xin Lian ^a   Liu, Shan Ling ^a   Zou, Juan ^a   Wang, He ^a  

^a SICHUAN UNIVERSITY   (China)

Author keywords

Apoptosis; MAPKs pathway; Mitochondrial pathway; Paris saponin II

Indexed keywords

EID: 84867499609     PISSN: 1672173X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (11)

1. Vassilopoulos Y. Paris Polyphylla in Medicine. A literary favour to world culture. Newsfinder, 2007; 9(5): 102-118.
2. Xiao X, Bai P, Bui Nguyen TM, et al. The antitumoral effect of Paris Saponin I associated with the induction of apoptosis through the mitochondrial pathway. Mol Cancer Ther, 2009; 8 (5): 1179-1188.
3. Vermes I, Haanen C, Steffens-Nakken H, et al. A novel assay for apoptosis. Flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labelled Annexin V. J Immunol Methods, 1995; 184 (1): 39-51.
4. Park JK, Kang MY, Kim YH, et al. PKC delta in preeclamptic placentas promotes Bax dissociation from 14-3-3 zeta through 14-3-3 zeta phosphorylation. Placenta, 2008; 29 (7): 584-592.
5. Cheung JY, Ong RC, Suen YK, et al. Polyphyllin D is a potent apoptosis inducer in drug-resistant HepG2 cells. Cancer Lett, 2005; 217(2): 203-211.
6. 2-induced apoptosis via inhibiting mitochondria- dependent caspase activation and the p38 MAPK pathway. Free Radic Biol Med, 2012; 3(4): 11O1-1110.
7. Lin JW, Chen JT, Hong CY, et al. Honokiol traverses the blood-brain barrierand induces apoptosis of neuroblastoma cells via an intrinsic bax-mitochondrion-cytochrome c-caspase protease pathway. Neuro Oncol, 2012; 14(3): 302-314.
8. Tan H, Ling H, He J, et al. Inhibition of ERK and activation of p38 are involved in diallyl disulfide induced apoptosis of leukemia HL-60 cells. Arch Pharm Res, 2008; 31(6):786-793.
9. Lee SR, Lo EH. Interactions between p38 mitogen-activated protein kinase and caspase-3 in cerebral endothelial cell death after hypoxia-reoxygenation. Stroke,2003; 34(11): 2704-2709.
10. Yan F, Wang M, Li J, et al. Gambogenic acid induced mitochondrial- dependentapoptosis and referred to phospho- Erk1/2 and phospho-p38 MAPK in human hepatoma HepG2 cells. Environ Toxicol Pharmacol, 2012; 33(2012): 1181-190.
11. Lee MS, Yuet-Wa JC, Kong SK, et al. Effects of polyphyllin D, a steroidal saponin in Paris polyphylla, in growth inhibition of human breast cancer cells and in xenograft. Cancer Biol Ther, 2005; 4(11): 1248-1254.