Phototriggered DNA phosphoramidate ligation in a tandem 5′-amine deprotection/3′-imidazole activated phosphate coupling reaction

Bioconjugate Chemistry

Volumn 23, Issue 10, 2012, Pages 2014-2019

  Cape, Jonathan L ^a   Edson, Joseph B ^a   Spencer, Liam P ^a   Declue, Michael S ^a   Ziock, Hans Joachim ^a   Maurer, Sarah ^a,b   Rasmussen, Steen ^a,c   Monnard, Pierre Alain ^a,b   Boncella, James M ^a  

^a LOS ALAMOS NATIONAL LABORATORY   (United States)

^b UNIVERSITY OF SOUTHERN DENMARK   (Denmark)

^c SANTA FE INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ASCORBIC ACID; DNA; PHOTOLYSIS; REACTION RATES; SOLUTIONS;

ACTIVATED PHOSPHATES; AMINE DEPROTECTION; COUPLING REACTION; DEPROTECTION; IMIDAZOL; LIGATION REACTIONS; NON-ENZYMATIC; PHOSPHORAMIDATES; PROTECTING GROUP; [CARBONYL;

OLIGONUCLEOTIDES;

ASCORBIC ACID; CARBAMIC ACID DERIVATIVE; IMIDAZOLE DERIVATIVE; N METHYL 4 PICOLINIUM CARBONYL IMIDAZOLE TRIFLATE; OLIGONUCLEOTIDE; PHOSPHATE; PHOSPHORAMIDIC ACID DERIVATIVE; PREBIOTIC AGENT; UNCLASSIFIED DRUG;

AQUEOUS SOLUTION; ARTICLE; CHEMICAL REACTION; DNA HAIRPIN; DNA TEMPLATE; ELECTRON TRANSPORT; LIGATION; LIGHT; METHODOLOGY; NUCLEIC ACID SYNTHESIS; PHOTOLYSIS;

EID: 84867492624     PISSN: 10431802     EISSN: 15204812     Source Type: Journal    
DOI: 10.1021/bc300093y     Document Type: Article

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