-
1
-
-
0024509701
-
Isolation of a cDNA clone derived from a blood-borne non-A, non-B viral hepatitis genome
-
Choo QL, Kuo G, Weiner AJ, Overby LR, Bradley DW, Houghton M. Isolation of a cDNA clone derived from a blood-borne non-A, non-B viral hepatitis genome. Science. 1989;244:359-362.
-
(1989)
Science
, vol.244
, pp. 359-362
-
-
Choo, Q.L.1
Kuo, G.2
Weiner, A.J.3
Overby, L.R.4
Bradley, D.W.5
Houghton, M.6
-
2
-
-
0035811625
-
Hepatitis C virus infection
-
Lauer GM, Walker BD. Hepatitis C virus infection. N Engl J Med. 2001; 345:41-52.
-
(2001)
N Engl J Med
, vol.345
, pp. 41-52
-
-
Lauer, G.M.1
Walker, B.D.2
-
3
-
-
1642288430
-
-
World Health Organization, July 2012. [Webpage on the Internet]
-
World Health Organization. Hepatitis C. Fact sheet N°164. July 2012. [Webpage on the Internet] http://www.who.int/mediacentre/factsheets/fs164/en/index.html. Accessed April 14, 2012.
-
(2012)
Hepatitis C. Fact sheet N°164
-
-
-
4
-
-
33646852746
-
The prevalence of hepatitis C virus infection in the United States, 1999 through 2002
-
Armstrong GL, Wasley A, Simard EP, McQuillan GM, Kuhnert WL, Alter MJ. The prevalence of hepatitis C virus infection in the United States, 1999 through 2002. Ann Intern Med. 2006;144:705-714.
-
(2006)
Ann Intern Med
, vol.144
, pp. 705-714
-
-
Armstrong, G.L.1
Wasley, A.2
Simard, E.P.3
McQuillan, G.M.4
Kuhnert, W.L.5
Alter, M.J.6
-
6
-
-
0036829816
-
Natural history of chronic hepatitis C
-
Seeff LB. Natural history of chronic hepatitis C. Hepatology. 2002;36(5 Suppl 1):S35-S46.
-
(2002)
Hepatology
, vol.36
, Issue.5 SUPPL. 1
-
-
Seeff, L.B.1
-
7
-
-
65449136656
-
Diagnosis, management, and treatment of hepatitis C: An update
-
Ghany MG, Strader DB, Thomas DL, Seeff LB. Diagnosis, management, and treatment of hepatitis C: an update. Hepatology. 2009;49:1335-1374.
-
(2009)
Hepatology
, vol.49
, pp. 1335-1374
-
-
Ghany, M.G.1
Strader, D.B.2
Thomas, D.L.3
Seeff, L.B.4
-
8
-
-
0022868893
-
Treatment of chronic non-A, non-B hepatitis with recombinant human alpha interferon. A preliminary report
-
Hoofnagle JH, Mullen KD, Jones DB, et al. Treatment of chronic non-A, non-B hepatitis with recombinant human alpha interferon. A preliminary report. N Engl J Med. 1986;315:1575-1578.
-
(1986)
N Engl J Med
, vol.315
, pp. 1575-1578
-
-
Hoofnagle, J.H.1
Mullen, K.D.2
Jones, D.B.3
-
9
-
-
17144455384
-
Histologic improvement of fibrosis in patients with hepatitis C who have sustained response to interferon therapy
-
Shiratori Y, Imazeki F, Moriyama M, et al. Histologic improvement of fibrosis in patients with hepatitis C who have sustained response to interferon therapy. Ann Intern Med. 2000;132:517-524.
-
(2000)
Ann Intern Med
, vol.132
, pp. 517-524
-
-
Shiratori, Y.1
Imazeki, F.2
Moriyama, M.3
-
10
-
-
10244245503
-
Interferon therapy for aged patients with chronic hepatitis C: Improved survival in patients exhibiting a biochemical response
-
Imai Y, Kasahara A, Tanaka H, et al. Interferon therapy for aged patients with chronic hepatitis C: improved survival in patients exhibiting a biochemical response. J Gastroenterol. 2004;39:1069-1077.
-
(2004)
J Gastroenterol
, vol.39
, pp. 1069-1077
-
-
Imai, Y.1
Kasahara, A.2
Tanaka, H.3
-
11
-
-
12144289051
-
Interferon treatment improves survival in chronic hepatitis C patients showing biochemical as well as virological responses by preventing liver-related death
-
Kasahara A, Tanaka H, Okanoue T, et al. Interferon treatment improves survival in chronic hepatitis C patients showing biochemical as well as virological responses by preventing liver-related death. J Viral Hepat. 2004;11:148-156.
-
(2004)
J Viral Hepat
, vol.11
, pp. 148-156
-
-
Kasahara, A.1
Tanaka, H.2
Okanoue, T.3
-
12
-
-
0036715591
-
Viruses and interferon: A fight for supremacy
-
Katze MG, He Y, Gale M Jr. Viruses and interferon: a fight for supremacy. Nat Rev Immunol. 2002;2:675-687.
-
(2002)
Nat Rev Immunol
, vol.2
, pp. 675-687
-
-
Katze, M.G.1
He, Y.2
Gale Jr., M.3
-
13
-
-
33644520948
-
Therapy of hepatitis C: From empiricism to eradication
-
Pawlotsky JM. Therapy of hepatitis C: From empiricism to eradication. Hepatology. 2006;43 Suppl 1:S207-S220.
-
(2006)
Hepatology
, vol.43
, Issue.SUPPL. 1
-
-
Pawlotsky, J.M.1
-
15
-
-
0026733674
-
A pilot study of ribavirin therapy for chronic hepatitis C
-
Di Bisceglie AM, Shindo M, Fong TL, et al. A pilot study of ribavirin therapy for chronic hepatitis C. Hepatology. 1992;16:649-654.
-
(1992)
Hepatology
, vol.16
, pp. 649-654
-
-
Di Bisceglie, A.M.1
Shindo, M.2
Fong, T.L.3
-
16
-
-
0028122848
-
A pilot study of combination therapy with ribavirin plus interferon alfa for interferon alfa-resistant chronic hepatitis C
-
Brillanti S, Garson J, Foli M, et al. A pilot study of combination therapy with ribavirin plus interferon alfa for interferon alfa-resistant chronic hepatitis C. Gastroenterology. 1994;107:812-817.
-
(1994)
Gastroenterology
, vol.107
, pp. 812-817
-
-
Brillanti, S.1
Garson, J.2
Foli, M.3
-
17
-
-
0032585237
-
Randomised trial of interferon alpha2b plus ribavirin for 48 weeks or for 24 weeks versus interferon alpha2b plus placebo for 48 weeks for treatment of chronic infection with hepatitis C virus. International Hepatitis Interventional Therapy Group (IHIT)
-
Poynard T, Marcellin P, Lee SS, et al. Randomised trial of interferon alpha2b plus ribavirin for 48 weeks or for 24 weeks versus interferon alpha2b plus placebo for 48 weeks for treatment of chronic infection with hepatitis C virus. International Hepatitis Interventional Therapy Group (IHIT). Lancet. 1998;352:1426-1432.
-
(1998)
Lancet
, vol.352
, pp. 1426-1432
-
-
Poynard, T.1
Marcellin, P.2
Lee, S.S.3
-
18
-
-
0345188811
-
Replication of subgenomic hepatitis C virus RNAs in a hepatoma cell line
-
Lohmann V, Körner F, Koch J, Herian U, Theilmann I, Bartenschlager R. Replication of subgenomic hepatitis C virus RNAs in a hepatoma cell line. Science. 1999;285:110-113.
-
(1999)
Science
, vol.285
, pp. 110-113
-
-
Lohmann, V.1
Körner, F.2
Koch, J.3
Herian, U.4
Theilmann, I.5
Bartenschlager, R.6
-
19
-
-
0000163169
-
Flaviviridae: The viruses and their replication
-
In:, 4th ed. Philadelphia, PA: Lippincott Williams & Wilkins
-
Lindenbach BD, Rice CM. Flaviviridae: The viruses and their replication. In: Fields Virology. Volume 1. 4th ed. Philadelphia, PA: Lippincott Williams & Wilkins; 2001.
-
(2001)
Fields Virology
, vol.1
-
-
Lindenbach, B.D.1
Rice, C.M.2
-
20
-
-
16044364658
-
Crystal structure of the hepatitis C virus NS3 protease domain complexed with a synthetic NS4A cofactor peptide
-
Kim JL, Morgenstern KA, Lin C, et al. Crystal structure of the hepatitis C virus NS3 protease domain complexed with a synthetic NS4A cofactor peptide. Cell. 1996;87:343-355.
-
(1996)
Cell
, vol.87
, pp. 343-355
-
-
Kim, J.L.1
Morgenstern, K.A.2
Lin, C.3
-
21
-
-
0030592514
-
The crystal structure of hepatitis C virus NS3 proteinase reveals a trypsin-like fold and a structural zinc binding site
-
Love RA, Parge HE, Wickersham JA, et al. The crystal structure of hepatitis C virus NS3 proteinase reveals a trypsin-like fold and a structural zinc binding site. Cell. 1996;87:331-342.
-
(1996)
Cell
, vol.87
, pp. 331-342
-
-
Love, R.A.1
Parge, H.E.2
Wickersham, J.A.3
-
22
-
-
0344201903
-
An NS3 protease inhibitor with antiviral effects in humans infected with hepatitis C virus
-
Lamarre D, Anderson PC, Bailey M, et al. An NS3 protease inhibitor with antiviral effects in humans infected with hepatitis C virus. Nature. 2003;426:186-189.
-
(2003)
Nature
, vol.426
, pp. 186-189
-
-
Lamarre, D.1
Anderson, P.C.2
Bailey, M.3
-
23
-
-
33644639990
-
SCH 503034, a mechanism-based inhibitor of hepatitis C virus NS3 protease, suppresses polyprotein maturation and enhances the antiviral activity of alpha interferon in replicon cells
-
Malcolm BA, Liu R, Lahser F, et al. SCH 503034, a mechanism-based inhibitor of hepatitis C virus NS3 protease, suppresses polyprotein maturation and enhances the antiviral activity of alpha interferon in replicon cells. Antimicrob Agents Chemother. 2006;50:1013-1020.
-
(2006)
Antimicrob Agents Chemother
, vol.50
, pp. 1013-1020
-
-
Malcolm, B.A.1
Liu, R.2
Lahser, F.3
-
24
-
-
84867677963
-
-
Merck, Accessed July 10, May 2011. Available at
-
Merck. Victrelis (boceprevir) prescribing information. May 2011. Available at: http://www.merck.com/product/usa/pi_circulars/v/victrelis/victrelis_pi.pdf. Accessed July 10, 2012.
-
(2012)
Victrelis (boceprevir) prescribing information
-
-
-
25
-
-
84963595028
-
-
Accessed December 14, FDA US Food and Drug Administration, Victrelis (boceprevir). Available at
-
FDA US Food and Drug Administration. Drug approval package. Victrelis (boceprevir). Available at http://www.accessdata.fda.gov/drugsatfda_docs/nda/2011/202258Orig1s000TOC.cfm. Accessed December 14, 2011.
-
(2011)
Drug approval package
-
-
-
26
-
-
79951868202
-
Characterization of human liver enzymes involved in the biotransformation of boceprevir, a hepatitis C virus protease inhibitor
-
Ghosal A, Yuan Y, Tong W, et al. Characterization of human liver enzymes involved in the biotransformation of boceprevir, a hepatitis C virus protease inhibitor. Drug Metab Dispos. 2011;39:510-521.
-
(2011)
Drug Metab Dispos
, vol.39
, pp. 510-521
-
-
Ghosal, A.1
Yuan, Y.2
Tong, W.3
-
27
-
-
0037169960
-
Implications of cytochrome P450 interactions when prescribing medication for hypertension
-
Flockhart DA, Tanus-Santos JE. Implications of cytochrome P450 interactions when prescribing medication for hypertension. Arch Intern Med. 2002;162:405-412.
-
(2002)
Arch Intern Med
, vol.162
, pp. 405-412
-
-
Flockhart, D.A.1
Tanus-Santos, J.E.2
-
28
-
-
84859955001
-
Review and management of drug interactions with boceprevir and telaprevir
-
Kiser JJ, Burton JR, Anderson PL, Everson GT. Review and management of drug interactions with boceprevir and telaprevir. Hepatology. 2012;55:1620-1628.
-
(2012)
Hepatology
, vol.55
, pp. 1620-1628
-
-
Kiser, J.J.1
Burton, J.R.2
Anderson, P.L.3
Everson, G.T.4
-
29
-
-
30344485556
-
Antiviral activity of SCH 503034, a HCV protease inhibitor, administered as monotherapy in hepatitis C genotype-1 (HCV-1) patients refractory to pegylated interferon (PEG-IFN-alpha)
-
Zeuzem S, Sarrazin C, Rouzier R, et al. Antiviral activity of SCH 503034, a HCV protease inhibitor, administered as monotherapy in hepatitis C genotype-1 (HCV-1) patients refractory to pegylated interferon (PEG-IFN-alpha). Hepatology. 2005;42 Suppl 1:S233-S234.
-
(2005)
Hepatology
, vol.42
, Issue.SUPPL. 1
-
-
Zeuzem, S.1
Sarrazin, C.2
Rouzier, R.3
-
30
-
-
53149111712
-
Clonal analysis of mutations selected in the HCV NS3 protease domain of genotype 1 non-responders treated with boceprevir (SCH503034)
-
Susser S, Welker MW, Zettler M, et al. Clonal analysis of mutations selected in the HCV NS3 protease domain of genotype 1 non-responders treated with boceprevir (SCH503034). J Hepatol. 2008;48 Suppl 2:S29.
-
(2008)
J Hepatol
, vol.48
, Issue.SUPPL. 2
-
-
Susser, S.1
Welker, M.W.2
Zettler, M.3
-
31
-
-
59749090086
-
Selection and characterization of hepatitis C virus replicons dually resistant to the polymerase and protease inhibitors HCV-796 and boceprevir (SCH 503034)
-
Flint M, Mullen S, Deatly AM, et al. Selection and characterization of hepatitis C virus replicons dually resistant to the polymerase and protease inhibitors HCV-796 and boceprevir (SCH 503034). Antimicrob Agents Chemother. 2009;53:401-411.
-
(2009)
Antimicrob Agents Chemother
, vol.53
, pp. 401-411
-
-
Flint, M.1
Mullen, S.2
Deatly, A.M.3
-
32
-
-
34247545612
-
Treatment of hepatitis C: Don't put all your eggs in one basket!
-
Pawlotsky JM. Treatment of hepatitis C: don't put all your eggs in one basket! Gastroenterology. 2007;132:1611-1615.
-
(2007)
Gastroenterology
, vol.132
, pp. 1611-1615
-
-
Pawlotsky, J.M.1
-
33
-
-
34247205808
-
SCH 503034, a novel hepatitis C virus protease inhibitor, plus pegylated interferon alpha-2b for genotype 1 nonresponders
-
Sarrazin C, Rouzier R, Wagner F, et al. SCH 503034, a novel hepatitis C virus protease inhibitor, plus pegylated interferon alpha-2b for genotype 1 nonresponders. Gastroenterology. 2007;132:1270-1278.
-
(2007)
Gastroenterology
, vol.132
, pp. 1270-1278
-
-
Sarrazin, C.1
Rouzier, R.2
Wagner, F.3
-
34
-
-
77956268467
-
Efficacy of boceprevir, an NS3 protease inhibitor, in combination with peginterferon alfa-2b and ribavirin in treatment-naive patients with genotype 1 hepatitis C infection (SPRINT-1): An open-label, randomised, multicentre phase 2 trial
-
Kwo PY, Lawitz EJ, McCone J, et al. Efficacy of boceprevir, an NS3 protease inhibitor, in combination with peginterferon alfa-2b and ribavirin in treatment-naive patients with genotype 1 hepatitis C infection (SPRINT-1): an open-label, randomised, multicentre phase 2 trial. Lancet. 2010;376:705-716.
-
(2010)
Lancet
, vol.376
, pp. 705-716
-
-
Kwo, P.Y.1
Lawitz, E.J.2
McCone, J.3
-
35
-
-
52649168519
-
Boceprevir (B) combination therapy in null responders (NR): Response dependent on interferon responsiveness
-
Schiff E, Poordad F, Jacobson I, et al. Boceprevir (B) combination therapy in null responders (NR): response dependent on interferon responsiveness. J Hepatol. 2008;48 Suppl 2:S46.
-
(2008)
J Hepatol
, vol.48
, Issue.SUPPL. 2
-
-
Schiff, E.1
Poordad, F.2
Jacobson, I.3
-
36
-
-
79953173221
-
Boceprevir for untreated chronic HCV genotype 1 infection
-
Poordad F, McCone J, Bacon BR, et al. Boceprevir for untreated chronic HCV genotype 1 infection. N Engl J Med. 2011;364:1195-1206.
-
(2011)
N Engl J Med
, vol.364
, pp. 1195-1206
-
-
Poordad, F.1
McCone, J.2
Bacon, B.R.3
-
37
-
-
79953176289
-
Boceprevir for previously treated chronic HCV genotype 1 infection
-
Bacon BR, Gordon SC, Lawitz E, et al. Boceprevir for previously treated chronic HCV genotype 1 infection. N Engl J Med. 2011;364: 1207-1217.
-
(2011)
N Engl J Med
, vol.364
, pp. 1207-1217
-
-
Bacon, B.R.1
Gordon, S.C.2
Lawitz, E.3
-
38
-
-
81155157226
-
Sustained virologic response and boceprevir resistance-associated variants observed in patients infected with HCV genotype 1a/1b when treated with boceprevir plus peginterferon alfa-2b/ribavirin
-
Brass C, Barnard RJO, Howe JA, et al. Sustained virologic response and boceprevir resistance-associated variants observed in patients infected with HCV genotype 1a/1b when treated with boceprevir plus peginterferon alfa-2b/ribavirin. J Hepatol. 2011;54 Suppl 1:S471-S472.
-
(2011)
J Hepatol
, vol.54
, Issue.SUPPL. 1
-
-
Brass, C.1
Barnard, R.J.O.2
Howe, J.A.3
-
39
-
-
84867554717
-
Sustained virologic response (SVR) in prior peginterferon/ribavirin (PR) treatment failures after retreatment with boceprevir (BOC)-+-PR: The provide study interim results
-
Bronowicki JP, Davis M, Flamm S, et al. Sustained virologic response (SVR) in prior peginterferon/ribavirin (PR) treatment failures after retreatment with boceprevir (BOC)-+-PR: the provide study interim results. J Hepatol. 2012;56 Suppl 2:S6.
-
(2012)
J Hepatol
, vol.56
, Issue.SUPPL. 2
-
-
Bronowicki, J.P.1
Davis, M.2
Flamm, S.3
-
40
-
-
79953764145
-
Long-term outcomes following combination treatment with boceprevir plus peg-intron/ribavirin (P/R) in patients with chronic hepatitis C, genotype 1 (CHC-G1)
-
Vierling JM, Ralston R, Lawitz EJ, et al. Long-term outcomes following combination treatment with boceprevir plus peg-intron/ribavirin (P/R) in patients with chronic hepatitis C, genotype 1 (CHC-G1). J Hepatol. 2010;52 Suppl 1:S470-S471.
-
(2010)
J Hepatol
, vol.52
, Issue.SUPPL. 1
-
-
Vierling, J.M.1
Ralston, R.2
Lawitz, E.J.3
-
42
-
-
33746535101
-
Peginterferon and ribavirin treatment in African American and Caucasian American patients with hepatitis C genotype 1
-
Conjeevaram HS, Fried MW, Jeffers LJ, et al. Peginterferon and ribavirin treatment in African American and Caucasian American patients with hepatitis C genotype 1. Gastroenterology. 2006;131:470-477.
-
(2006)
Gastroenterology
, vol.131
, pp. 470-477
-
-
Conjeevaram, H.S.1
Fried, M.W.2
Jeffers, L.J.3
-
43
-
-
70349292099
-
Genetic variation in IL28B predicts hepatitis C treatment-induced viral clearance
-
Ge D, Fellay J, Thompson AJ, et al. Genetic variation in IL28B predicts hepatitis C treatment-induced viral clearance. Nature. 2009;461: 399-401.
-
(2009)
Nature
, vol.461
, pp. 399-401
-
-
Ge, D.1
Fellay, J.2
Thompson, A.J.3
-
44
-
-
70349966196
-
Genetic variation in IL28B and spontaneous clearance of hepatitis C virus
-
Thomas DL, Thio CL, Martin MP, et al. Genetic variation in IL28B and spontaneous clearance of hepatitis C virus. Nature. 2009;461: 798-801.
-
(2009)
Nature
, vol.461
, pp. 798-801
-
-
Thomas, D.L.1
Thio, C.L.2
Martin, M.P.3
-
45
-
-
77953881002
-
Interleukin-28B polymorphism improves viral kinetics and is the strongest pretreatment predictor of sustained virologic response in genotype 1 hepatitis C virus
-
Thompson AJ, Muir AJ, Sulkowski MS, et al. Interleukin-28B polymorphism improves viral kinetics and is the strongest pretreatment predictor of sustained virologic response in genotype 1 hepatitis C virus. Gastroenterology. 2010;139:120-129.
-
(2010)
Gastroenterology
, vol.139
, pp. 120-129
-
-
Thompson, A.J.1
Muir, A.J.2
Sulkowski, M.S.3
-
47
-
-
84855245619
-
Phase III results in genotype 1 naïve patients: Predictors of response with boceprevir and telaprevir combined with pegylated interferon and ribavirin
-
Kwo PY. Phase III results in genotype 1 naïve patients: predictors of response with boceprevir and telaprevir combined with pegylated interferon and ribavirin. Liver Int. 2012;32 Suppl 1:S39-S43.
-
(2012)
Liver Int
, vol.32
, Issue.SUPPL. 1
-
-
Kwo, P.Y.1
-
48
-
-
0037179698
-
Peginterferon alfa-2a plus ribavirin for chronic hepatitis C virus infection
-
Fried MW, Shiffman ML, Reddy KR, et al. Peginterferon alfa-2a plus ribavirin for chronic hepatitis C virus infection. N Engl J Med. 2002;347: 975-982.
-
(2002)
N Engl J Med
, vol.347
, pp. 975-982
-
-
Fried, M.W.1
Shiffman, M.L.2
Reddy, K.R.3
-
49
-
-
77949773445
-
ITPA gene variants protect against anaemia in patients treated for chronic hepatitis C
-
Fellay J, Thompson A, Ge D, et al. ITPA gene variants protect against anaemia in patients treated for chronic hepatitis C. Nature. 2010;464: 405-408.
-
(2010)
Nature
, vol.464
, pp. 405-408
-
-
Fellay, J.1
Thompson, A.2
Ge, D.3
-
50
-
-
77957326039
-
Variants in the ITPA gene protect against ribavirin-induced hemolytic anemia and decrease the need for ribavirin dose reduction
-
Thompson AJ, Fellay J, Patel K, et al. Variants in the ITPA gene protect against ribavirin-induced hemolytic anemia and decrease the need for ribavirin dose reduction. Gastroenterology. 2010;139:1181-1189.
-
(2010)
Gastroenterology
, vol.139
, pp. 1181-1189
-
-
Thompson, A.J.1
Fellay, J.2
Patel, K.3
-
51
-
-
84867096880
-
A randomized trial comparing ribavirin dose reduction versus erythropoietin for anemia management in previously untreated patients with chronic hepatitis C receiving boceprevir plus peginterferon/ribavirin
-
Poordad F, Lawitz EJ, Reddy KR, et al. A randomized trial comparing ribavirin dose reduction versus erythropoietin for anemia management in previously untreated patients with chronic hepatitis C receiving boceprevir plus peginterferon/ribavirin. J Hepatol. 2012;56 Suppl 2:S559.
-
(2012)
J Hepatol
, vol.56
, Issue.SUPPL. 2
-
-
Poordad, F.1
Lawitz, E.J.2
Reddy, K.R.3
-
52
-
-
44849113503
-
Cutting edge: Programmed death-1 expression is increased on immunocytes in chronic hepatitis C virus and predicts failure of response to antiviral therapy: Race-dependent differences
-
Golden-Mason L, Klarquist J, Wahed AS, Rosen HR. Cutting edge: Programmed death-1 expression is increased on immunocytes in chronic hepatitis C virus and predicts failure of response to antiviral therapy: race-dependent differences. J Immunol. 2008;180:3637-3641.
-
(2008)
J Immunol
, vol.180
, pp. 3637-3641
-
-
Golden-Mason, L.1
Klarquist, J.2
Wahed, A.S.3
Rosen, H.R.4
-
53
-
-
33750691709
-
PD-1 expression in acute hepatitis C virus (HCV) infection is associated with HCV-specific CD8 exhaustion
-
Urbani S, Amadei B, Tola D, et al. PD-1 expression in acute hepatitis C virus (HCV) infection is associated with HCV-specific CD8 exhaustion. J Virol. 2006;80:11398-11403.
-
(2006)
J Virol
, vol.80
, pp. 11398-11403
-
-
Urbani, S.1
Amadei, B.2
Tola, D.3
-
54
-
-
84861185607
-
A predictive model of treatment outcome in patients with chronic HCV infection using IL28B and PD-1 genotyping
-
Vidal-Castiñeira JR, López-Vázquez A, Alonso-Arias R, et al. A predictive model of treatment outcome in patients with chronic HCV infection using IL28B and PD-1 genotyping. J Hepatol. 2012;56: 1230-1238.
-
(2012)
J Hepatol
, vol.56
, pp. 1230-1238
-
-
Vidal-Castiñeira, J.R.1
López-Vázquez, A.2
Alonso-Arias, R.3
-
55
-
-
84867497865
-
-
Abstract 47 presented at the 19th Conference on Retroviruses and Opportunistic Infections, Seattle, WA; March 5-8
-
Sulkowski M, Pol S, Cooper C, et al. Boceprevir+ pegylated interferon + ribavirin for the treatment of HCV/HIV-coinfected patients: end of treatment (week 48) interim results. Abstract 47 presented at the 19th Conference on Retroviruses and Opportunistic Infections, Seattle, WA; March 5-8, 2012.
-
(2012)
Boceprevir+ pegylated interferon + ribavirin for the treatment of HCV/HIV-coinfected patients: End of treatment (week 48) interim results
-
-
Sulkowski, M.1
Pol, S.2
Cooper, C.3
-
56
-
-
84857368831
-
UK consensus guidelines for the use of the protease inhibitors boceprevir and telaprevir in genotype 1 chronic hepatitis C infected patients
-
Ramachandran P, Fraser A, Agarwal K, et al. UK consensus guidelines for the use of the protease inhibitors boceprevir and telaprevir in genotype 1 chronic hepatitis C infected patients. Aliment Pharmacol Ther. 2012;35:647-662.
-
(2012)
Aliment Pharmacol Ther
, vol.35
, pp. 647-662
-
-
Ramachandran, P.1
Fraser, A.2
Agarwal, K.3
-
57
-
-
33644804915
-
Limitation of combination therapy of interferon and ribavirin for older patients with chronic hepatitis C
-
Iwasaki Y, Ikeda H, Araki Y, et al. Limitation of combination therapy of interferon and ribavirin for older patients with chronic hepatitis C. Hepatology. 2006;43:54-63.
-
(2006)
Hepatology
, vol.43
, pp. 54-63
-
-
Iwasaki, Y.1
Ikeda, H.2
Araki, Y.3
-
58
-
-
84867566926
-
A 12-week interferon-free regimen of ABT-450/R, ABT-072, and ribavirin was well tolerated and achieved sustained virologic response in 91% of treatment-naive HCV IL28B-CC genotype-1-infected subjects
-
Lawitz E, Poordad F, Kowdley KV, et al. A 12-week interferon-free regimen of ABT-450/R, ABT-072, and ribavirin was well tolerated and achieved sustained virologic response in 91% of treatment-naive HCV IL28B-CC genotype-1-infected subjects. J Hepatol. 2012;56 Suppl 2:S7.
-
(2012)
J Hepatol
, vol.56
, Issue.SUPPL. 2
-
-
Lawitz, E.1
Poordad, F.2
Kowdley, K.V.3
-
59
-
-
84863678711
-
High SVR rate in treatment-naïve HCV genotype 1a and 1b patients treated for 12 weeks with an interferon-free all-oral quad regimen: Interim results
-
Sulkowski M, Rodriguez-Torres M, Lawitz E, et al. High SVR rate in treatment-naïve HCV genotype 1a and 1b patients treated for 12 weeks with an interferon-free all-oral quad regimen: interim results. J Hepatol. 2012;56 Suppl 2:S559.
-
(2012)
J Hepatol
, vol.56
, Issue.SUPPL. 2
-
-
Sulkowski, M.1
Rodriguez-Torres, M.2
Lawitz, E.3
-
61
-
-
84860315408
-
Maximizing opportunities and avoiding mistakes in triple therapy for hepatitis C virus
-
Barritt AS, Fried MW. Maximizing opportunities and avoiding mistakes in triple therapy for hepatitis C virus. Gastroenterology. 2012;14: 1314-1323.
-
(2012)
Gastroenterology
, vol.14
, pp. 1314-1323
-
-
Barritt, A.S.1
Fried, M.W.2
-
62
-
-
84864592321
-
Boceprevir: A novel NS3/4 protease inhibitor for the treatment of hepatitis C
-
Klibanov OM, Vickery SB, Olin JL, et al. Boceprevir: a novel NS3/4 protease inhibitor for the treatment of hepatitis C. Pharmacotherapy. 2012;32:173-190.
-
(2012)
Pharmacotherapy
, vol.32
, pp. 173-190
-
-
Klibanov, O.M.1
Vickery, S.B.2
Olin, J.L.3
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