-
1
-
-
34250020201
-
Hepatocellular carcinoma: Epidemiology and molecular carcinogenesis
-
DOI 10.1053/j.gastro.2007.04.061, PII S0016508507007998
-
El-Serag HB, Rudolph KL: Hepatocellular carcinoma: Epidemiology and molecular carcinogenesis. Gastroenterology 2007; 132: 2557-2576 (Pubitemid 46890874)
-
(2007)
Gastroenterology
, vol.132
, Issue.7
, pp. 2557-2576
-
-
El-Serag, H.B.1
Rudolph, K.L.2
-
3
-
-
70649097572
-
Beyond Milan criteria - chances and risks of expanding transplantation criteria for HCC patients with liver cirrhosis
-
Koschny R, Schmidt J, Ganten TM: Beyond Milan criteria - chances and risks of expanding transplantation criteria for HCC patients with liver cirrhosis. Clin Transplant 2009; 23(suppl 21):49-60
-
(2009)
Clin Transplant
, vol.23
, Issue.SUPPL. 21
, pp. 49-60
-
-
Koschny, R.1
Schmidt, J.2
Ganten, T.M.3
-
4
-
-
0141491273
-
Hepatocellular carcinoma
-
DOI 10.1016/S0140-6736(03)14964-1
-
Llovet JM, Burroughs A, Bruix J: Hepatocellular carcinoma. Lancet 2003; 362: 1907- 1917 (Pubitemid 37518510)
-
(2003)
Lancet
, vol.362
, Issue.9399
, pp. 1907-1917
-
-
Llovet, J.M.1
Burroughs, A.2
Bruix, J.3
-
5
-
-
47949116252
-
Sorafenib in advanced hepatocellular carcinoma
-
Llovet JM, Ricci S, Mazzaferro V, Hilgard P, Gane E, Blanc JF, de Oliveira AC, Santoro A, Raoul JL, Forner A, Schwartz M, Porta C, Zeuzem S, Bolondi L, Greten TF, Galle PR, Seitz JF, Borbath I, Haussinger D, Giannaris T, Shan M, Moscovici M, Voliotis D, Bruix J: Sorafenib in advanced hepatocellular carcinoma. N Engl J Med 2008; 359: 378-390
-
(2008)
N Engl J Med
, vol.359
, pp. 378-390
-
-
Llovet, J.M.1
Ricci, S.2
Mazzaferro, V.3
Hilgard, P.4
Gane, E.5
Blanc, J.F.6
De Oliveira, A.C.7
Santoro, A.8
Raoul, J.L.9
Forner, A.10
Schwartz, M.11
Porta, C.12
Zeuzem, S.13
Bolondi, L.14
Greten, T.F.15
Galle, P.R.16
Seitz, J.F.17
Borbath, I.18
Haussinger, D.19
Giannaris, T.20
Shan, M.21
Moscovici, M.22
Voliotis, D.23
Bruix, J.24
more..
-
6
-
-
57749189578
-
Efficacy and safety of sorafenib in patients in the Asia-Pacific region with advanced hepatocellular carcinoma: A phase III randomised, double-blind, placebo-controlled trial
-
Cheng AL, Kang YK, Chen Z, Tsao CJ, Qin S, Kim JS, Luo R, Feng J, Ye S, Yang TS, Xu J, Sun Y, Liang H, Liu J, Wang J, Tak WY, Pan H, Burock K, Zou J, Voliotis D, Guan Z: Efficacy and safety of sorafenib in patients in the Asia-Pacific region with advanced hepatocellular carcinoma: A phase III randomised, double-blind, placebo-controlled trial. Lancet Oncol 2009; 10: 25-34
-
(2009)
Lancet Oncol
, vol.10
, pp. 25-34
-
-
Cheng, A.L.1
Kang, Y.K.2
Chen, Z.3
Tsao, C.J.4
Qin, S.5
Kim, J.S.6
Luo, R.7
Feng, J.8
Ye, S.9
Yang, T.S.10
Xu, J.11
Sun, Y.12
Liang, H.13
Liu, J.14
Wang, J.15
Tak, W.Y.16
Pan, H.17
Burock, K.18
Zou, J.19
Voliotis, D.20
Guan, Z.21
more..
-
7
-
-
33749017926
-
Phase II study of sorafenib in patients with advanced hepatocellular carcinoma
-
DOI 10.1200/JCO.2005.01.3441
-
Abou-Alfa GK, Schwartz L, Ricci S, Amadori D, Santoro A, Figer A, De Greve J, Douillard JY, Lathia C, Schwartz B, Taylor I, Moscovici M, Saltz LB: Phase II study of sorafenib in patients with advanced hepatocellular carcinoma. J Clin Oncol 2006; 24: 4293-4300 (Pubitemid 46630787)
-
(2006)
Journal of Clinical Oncology
, vol.24
, Issue.26
, pp. 4293-4300
-
-
Abou-Alfa, G.K.1
Schwartz, L.2
Ricci, S.3
Amadori, D.4
Santoro, A.5
Figer, A.6
De Greve, J.7
Douillard, J.-Y.8
Lathia, C.9
Schwartz, B.10
Taylor, I.11
Moscovici, M.12
Saltz, L.B.13
-
8
-
-
67651095716
-
Safety and efficacy of sorafenib in patients with advanced hepatocellular carcinoma in consideration of concomitant stage of liver cirrhosis
-
Worns MA, Weinmann A, Pfingst K, Schulte- Sasse C, Messow CM, Schulze-Bergkamen H, Teufel A, Schuchmann M, Kanzler S, Duber C, Otto G, Galle PR: Safety and efficacy of sorafenib in patients with advanced hepatocellular carcinoma in consideration of concomitant stage of liver cirrhosis. J Clin Gastroenterol 2009; 43: 489-495
-
(2009)
J Clin Gastroenterol
, vol.43
, pp. 489-495
-
-
Worns, M.A.1
Weinmann, A.2
Pfingst, K.3
Schulte- Sasse, C.4
Messow, C.M.5
Schulze-Bergkamen, H.6
Teufel, A.7
Schuchmann, M.8
Kanzler, S.9
Duber, C.10
Otto, G.11
Galle, P.R.12
-
9
-
-
82355192537
-
Global investigation of therapeutic decisions in hepatocellular carcinoma and of its treatment with sorafenib (GIDEON) second interim analysis in more than 1,500 patients: Clinical findings in patients with liver dysfunction
-
Marrero JA, Lencioni R, Kudo M, Ye S, Nakajima K, Cihon F, Venook AP: Global investigation of therapeutic decisions in hepatocellular carcinoma and of its treatment with sorafenib (GIDEON) second interim analysis in more than 1,500 patients: Clinical findings in patients with liver dysfunction. J Clin Oncol 2011; 29
-
(2011)
J Clin Oncol
, pp. 29
-
-
Marrero, J.A.1
Lencioni, R.2
Kudo, M.3
Ye, S.4
Nakajima, K.5
Cihon, F.6
Venook, A.P.7
-
10
-
-
75649116842
-
Early skin toxicity as a predictive factor for tumor control in hepatocellular carcinoma patients treated with sorafenib
-
Vincenzi B, Santini D, Russo A, Addeo R, Giuliani F, Montella L, Rizzo S, Venditti O, Frezza AM, Caraglia M, Colucci G, Del Prete S, Tonini G: Early skin toxicity as a predictive factor for tumor control in hepatocellular carcinoma patients treated with sorafenib. Oncologist 2010; 15: 85-92
-
(2010)
Oncologist
, vol.15
, pp. 85-92
-
-
Vincenzi, B.1
Santini, D.2
Russo, A.3
Addeo, R.4
Giuliani, F.5
Montella, L.6
Rizzo, S.7
Venditti, O.8
Frezza, A.M.9
Caraglia, M.10
Colucci, G.11
Del Prete, S.12
Tonini, G.13
-
11
-
-
28844480321
-
Management of hepatocellular carcinoma
-
DOI 10.1002/hep.20933
-
Bruix J, Sherman M: Management of hepatocellular carcinoma. Hepatology 2005; 42: 1208-1236 (Pubitemid 43112690)
-
(2005)
Hepatology
, vol.42
, Issue.5
, pp. 1208-1236
-
-
Bruix, J.1
Sherman, M.2
-
12
-
-
57349090407
-
Gene expression in fixed tissues and outcome in hepatocellular carcinoma
-
Hoshida Y, Villanueva A, Kobayashi M, Peix J, Chiang DY, Camargo A, Gupta S, Moore J, Wrobel MJ, Lerner J, Reich M, Chan JA, Glickman JN, Ikeda K, Hashimoto M, Watanabe G, Daidone MG, Roayaie S, Schwartz M, Thung S, Salvesen HB, Gabriel S, Mazzaferro V, Bruix J, Friedman SL, Kumada H, Llovet JM, Golub TR: Gene expression in fixed tissues and outcome in hepatocellular carcinoma. N Engl J Med 2008; 359: 1995- 2004
-
(2008)
N Engl J Med
, vol.359
, pp. 1995-2004
-
-
Hoshida, Y.1
Villanueva, A.2
Kobayashi, M.3
Peix, J.4
Chiang, D.Y.5
Camargo, A.6
Gupta, S.7
Moore, J.8
Wrobel, M.J.9
Lerner, J.10
Reich, M.11
Chan, J.A.12
Glickman, J.N.13
Ikeda, K.14
Hashimoto, M.15
Watanabe, G.16
Daidone, M.G.17
Roayaie, S.18
Schwartz, M.19
Thung, S.20
Salvesen, H.B.21
Gabriel, S.22
Mazzaferro, V.23
Bruix, J.24
Friedman, S.L.25
Kumada, H.26
Llovet, J.M.27
Golub, T.R.28
more..
-
13
-
-
79955401037
-
Combining clinical, pathology, and gene expression data to predict recurrence of hepatocellular carcinoma
-
Villanueva A, Hoshida Y, Battiston C, Tovar V, Sia D, Alsinet C, Cornella H, Liberzon A, Kobayashi M, Kumada H, Thung SN, Bruix J, Newell P, April C, Fan JB, Roayaie S, Mazzaferro V, Schwartz ME, Llovet JM: Combining clinical, pathology, and gene expression data to predict recurrence of hepatocellular carcinoma. Gastroenterology 2011; 140: 1501-1512.e2
-
(2011)
Gastroenterology
, vol.140
-
-
Villanueva, A.1
Hoshida, Y.2
Battiston, C.3
Tovar, V.4
Sia, D.5
Alsinet, C.6
Cornella, H.7
Liberzon, A.8
Kobayashi, M.9
Kumada, H.10
Thung, S.N.11
Bruix, J.12
Newell, P.13
April, C.14
Fan, J.B.15
Roayaie, S.16
Mazzaferro, V.17
Schwartz, M.E.18
Llovet, J.M.19
-
14
-
-
80455158366
-
Gene expression- based chemical genomics identifies potential therapeutic drugs in hepatocellular carcinoma
-
Chen MH, Yang WL, Lin KT, Liu CH, Liu YW, Huang KW, Chang PM, Lai JM, Hsu CN, Chao KM, Kao CY, Huang CY: Gene expression- based chemical genomics identifies potential therapeutic drugs in hepatocellular carcinoma. PLoS One 2011; 6:e27186
-
(2011)
PLoS One
, vol.6
-
-
Chen, M.H.1
Yang, W.L.2
Lin, K.T.3
Liu, C.H.4
Liu, Y.W.5
Huang, K.W.6
Chang, P.M.7
Lai, J.M.8
Hsu, C.N.9
Chao, K.M.10
Kao, C.Y.11
Huang, C.Y.12
-
15
-
-
80054954581
-
Predicting the treatment effect of sorafenib using serum angiogenesis markers in patients with hepatocellular carcinoma
-
Miyahara K, Nouso K, Tomoda T, Kobayashi S, Hagihara H, Kuwaki K, Toshimori J, Onishi H, Ikeda F, Miyake Y, Nakamura S, Shiraha H, Takaki A, Yamamoto K: Predicting the treatment effect of sorafenib using serum angiogenesis markers in patients with hepatocellular carcinoma. J Gastroenterol Hepatol 2011; 26: 1604-1611
-
(2011)
J Gastroenterol Hepatol
, vol.26
, pp. 1604-1611
-
-
Miyahara, K.1
Nouso, K.2
Tomoda, T.3
Kobayashi, S.4
Hagihara, H.5
Kuwaki, K.6
Toshimori, J.7
Onishi, H.8
Ikeda, F.9
Miyake, Y.10
Nakamura, S.11
Shiraha, H.12
Takaki, A.13
Yamamoto, K.14
-
16
-
-
68449100731
-
Serum alpha-fetoprotein response as a surrogate for clinical outcome in patients receiving systemic therapy for advanced hepatocellular carcinoma
-
Vora SR, Zheng H, Stadler ZK, Fuchs CS, Zhu AX: Serum alpha-fetoprotein response as a surrogate for clinical outcome in patients receiving systemic therapy for advanced hepatocellular carcinoma. Oncologist 2009; 14: 717-725
-
(2009)
Oncologist
, vol.14
, pp. 717-725
-
-
Vora, S.R.1
Zheng, H.2
Stadler, Z.K.3
Fuchs, C.S.4
Zhu, A.X.5
-
17
-
-
77957559384
-
Early alpha-fetoprotein response predicts treatment efficacy of antiangiogenic systemic therapy in patients with advanced hepatocellular carcinoma
-
Shao YY, Lin ZZ, Hsu C, Shen YC, Hsu CH, Cheng AL: Early alpha-fetoprotein response predicts treatment efficacy of antiangiogenic systemic therapy in patients with advanced hepatocellular carcinoma. Cancer 2010; 116: 4590-4596
-
(2010)
Cancer
, vol.116
, pp. 4590-4596
-
-
Shao, Y.Y.1
Lin, Z.Z.2
Hsu, C.3
Shen, Y.C.4
Hsu, C.H.5
Cheng, A.L.6
-
18
-
-
45749152254
-
Erlotinib-induced skin rash. Pathogenesis, clinical significance and management in pancreatic cancer patients
-
Saif MW, Merikas I, Tsimboukis S, Syrigos K: Erlotinib-induced skin rash. Pathogenesis, clinical significance and management in pancreatic cancer patients. JOP 2008; 9: 267- 274 (Pubitemid 351864886)
-
(2008)
Journal of the Pancreas
, vol.9
, Issue.3
, pp. 267-274
-
-
Saif, M.W.1
Merikas, I.2
Tsimboukis, S.3
Syrigos, K.4
-
19
-
-
80955142670
-
A single center experience of sorafenib in advanced hepatocellular carcinoma patients: Evaluation of prognostic factors
-
Song T, Zhang W, Wu Q, Kong D, Ma W: A single center experience of sorafenib in advanced hepatocellular carcinoma patients: Evaluation of prognostic factors. Eur J Gastroenterol Hepatol 2011; 23: 1233-1238
-
(2011)
Eur J Gastroenterol Hepatol
, vol.23
, pp. 1233-1238
-
-
Song, T.1
Zhang, W.2
Wu, Q.3
Kong, D.4
Ma, W.5
-
20
-
-
84864360500
-
Diarrhea predicts a positive response to sorafenib in patients with advanced hepatocellular carcinoma
-
Bettinger D, Schultheiss M, Knuppel E, Thimme R, Blum HE, Spangenberg HC: Diarrhea predicts a positive response to sorafenib in patients with advanced hepatocellular carcinoma. Hepatology 2012; 56: 789-790
-
(2012)
Hepatology
, vol.56
, pp. 789-790
-
-
Bettinger, D.1
Schultheiss, M.2
Knuppel, E.3
Thimme, R.4
Blum, H.E.5
Spangenberg, H.C.6
-
21
-
-
84855177596
-
Sorafenib-induced diarrhea and hypophosphatemia: Mechanisms and therapeutic implications
-
Mir O, Coriat R, Boudou-Rouquette P, Durand JP, Goldwasser F: Sorafenib-induced diarrhea and hypophosphatemia: Mechanisms and therapeutic implications. Ann Oncol 2012; 23: 280-281
-
(2012)
Ann Oncol
, vol.23
, pp. 280-281
-
-
Mir, O.1
Coriat, R.2
Boudou-Rouquette, P.3
Durand, J.P.4
Goldwasser, F.5
-
22
-
-
84867854458
-
Sorafenib exposure decreases over time in patients with hepatocellular carcinoma
-
Epub ahead of print
-
Arrondeau J, Mir O, Boudou-Rouquette P, Coriat R, Ropert S, Dumas G, Rodrigues MJ, Rousseau B, Blanchet B, Goldwasser F: Sorafenib exposure decreases over time in patients with hepatocellular carcinoma. Invest New Drugs 2011, Epub ahead of print
-
(2011)
Invest New Drugs
-
-
Arrondeau, J.1
Mir, O.2
Boudou-Rouquette, P.3
Coriat, R.4
Ropert, S.5
Dumas, G.6
Rodrigues, M.J.7
Rousseau, B.8
Blanchet, B.9
Goldwasser, F.10
-
23
-
-
79952828428
-
Enhancing the clinical activity of sorafenib through dose escalation: Rationale and current experience
-
Semrad TJ, Gandara DR, Lara PN Jr: Enhancing the clinical activity of sorafenib through dose escalation: Rationale and current experience. Ther Adv Med Oncol 2011; 3: 95-100
-
(2011)
Ther Adv Med Oncol
, vol.3
, pp. 95-100
-
-
Semrad, T.J.1
Gandara, D.R.2
Lara Jr., P.N.3
-
24
-
-
80055017402
-
Safety and efficacy of sorafenib in hepatocellular carcinoma: The impact of the Child-Pugh score
-
Hollebecque A, Cattan S, Romano O, Sergent G, Mourad A, Louvet A, Dharancy S, Boleslawski E, Truant S, Pruvot FR, Hebbar M, Ernst O, Mathurin P: Safety and efficacy of sorafenib in hepatocellular carcinoma: The impact of the Child-Pugh score. Aliment Pharmacol Ther 2011; 34: 1193-1201
-
(2011)
Aliment Pharmacol Ther
, vol.34
, pp. 1193-1201
-
-
Hollebecque, A.1
Cattan, S.2
Romano, O.3
Sergent, G.4
Mourad, A.5
Louvet, A.6
Dharancy, S.7
Boleslawski, E.8
Truant, S.9
Pruvot, F.R.10
Hebbar, M.11
Ernst, O.12
Mathurin, P.13
-
25
-
-
80053041858
-
Safety and efficacy of sorafenib in patients with hepatocellular carcinoma (HCC) and Child-Pugh A versus B cirrhosis
-
Abou-Alfa GK, Amadori D, Santoro A, Figer A, De Greve J, Lathia C, Voliotis D, Anderson S, Moscovici M, Ricci S: Safety and efficacy of sorafenib in patients with hepatocellular carcinoma (HCC) and Child-Pugh A versus B cirrhosis. Gastrointest Cancer Res 2011; 4: 40-44
-
(2011)
Gastrointest Cancer Res
, vol.4
, pp. 40-44
-
-
Abou-Alfa, G.K.1
Amadori, D.2
Santoro, A.3
Figer, A.4
De Greve, J.5
Lathia, C.6
Voliotis, D.7
Anderson, S.8
Moscovici, M.9
Ricci, S.10
-
26
-
-
0032898237
-
Natural history of untreated nonsurgical hepatocellular carcinoma: Rationale for the design and evaluation of therapeutic trials
-
DOI 10.1002/hep.510290145
-
Llovet JM, Bustamante J, Castells A, Vilana R, Ayuso Mdel C, Sala M, Bru C, Rodes J, Bruix J: Natural history of untreated nonsurgical hepatocellular carcinoma: Rationale for the design and evaluation of therapeutic trials. Hepatology 1999; 29: 62-67 (Pubitemid 29023987)
-
(1999)
Hepatology
, vol.29
, Issue.1
, pp. 62-67
-
-
Llovet, J.M.1
Bustamante, J.2
Castells, A.3
Vilana, R.4
Del Carmen Avuso, M.5
Sala, M.6
Bru, C.7
Rodes, J.8
Bruix, J.9
-
27
-
-
0031845886
-
Natural history of untreated primary hepatocellular carcinoma: A retrospective study of 157 patients
-
DOI 10.1097/00000421-199808000-00014
-
Pawarode A, Voravud N, Sriuranpong V, Kullavanijaya P, Patt YZ: Natural history of untreated primary hepatocellular carcinoma: A retrospective study of 157 patients. Am J Clin Oncol 1998; 21: 386-391 (Pubitemid 28366909)
-
(1998)
American Journal of Clinical Oncology: Cancer Clinical Trials
, vol.21
, Issue.4
, pp. 386-391
-
-
Pawarode, A.1
Voravud, N.2
Sriuranpong, V.3
Kullavanijaya, P.4
Patt, Y.Z.5
-
28
-
-
33846148701
-
Sorafenib in advanced clear-cell renal-cell carcinoma
-
DOI 10.1056/NEJMoa060655
-
Escudier B, Eisen T, Stadler WM, Szczylik C, Oudard S, Siebels M, Negrier S, Chevreau C, Solska E, Desai AA, Rolland F, Demkow T, Hutson TE, Gore M, Freeman S, Schwartz B, Shan M, Simantov R, Bukowski RM: Sorafenib in advanced clear-cell renal-cell carcinoma. N Engl J Med 2007; 356: 125-134 (Pubitemid 46089673)
-
(2007)
New England Journal of Medicine
, vol.356
, Issue.2
, pp. 125-134
-
-
Escudier, B.1
Eisen, T.2
Stadler, W.M.3
Szczylik, C.4
Oudard, S.5
Siebels, M.6
Negrier, S.7
Chevreau, C.8
Solska, E.9
Desai, A.A.10
Rolland, F.11
Demkow, T.12
Hutson, T.E.13
Gore, M.14
Freeman, S.15
Schwartz, B.16
Shan, M.17
Simantov, R.18
Bukowski, R.M.19
|