Decreased serum Fetuin-A levels are associated with coronary artery diseases

Internal Medicine

Volumn 49, Issue 13, 2010, Pages 1281-1285

  Bilgir, Oktay ^a   Kebapcilar, Levent ^a   Bilgir, Ferda ^a   Bozkaya, Giray ^a   Yildiz, Yasar ^a   Pinar, Pelin ^a   Tastan, Ahmet ^b  

^a UNIVERSITY OF HEALTH SCIENCES   (Turkey)

^b Izmir Sifa Hastanesi   (Turkey)

Author keywords

Acute coronary syndrome; Cellular adhesion molecules; Fetuin A; hs CRP

Indexed keywords

C REACTIVE PROTEIN; CELL ADHESION MOLECULE; FETUIN A; INTERCELLULAR ADHESION MOLECULE 1; VASCULAR CELL ADHESION MOLECULE 1; AHSG PROTEIN, HUMAN; BIOLOGICAL MARKER; PLASMA PROTEIN;

ACUTE CORONARY SYNDROME; ADULT; ANGIOCARDIOGRAPHY; ARTICLE; CONTROLLED STUDY; CORONARY ARTERY ATHEROSCLEROSIS; CORONARY ARTERY DISEASE; DISEASE ASSOCIATION; FEMALE; HEART INFARCTION; HUMAN; MAJOR CLINICAL STUDY; MALE; PATHOPHYSIOLOGY; PATIENT CODING; PROTEIN ANALYSIS; PROTEIN BLOOD LEVEL; PROTEIN FUNCTION; STABLE ANGINA PECTORIS; THORAX PAIN; AGED; ANGINA PECTORIS; BLOOD; CASE CONTROL STUDY; METABOLISM; MIDDLE AGED; RETROSPECTIVE STUDY; VERY ELDERLY;

ADULT; AGED; AGED, 80 AND OVER; ANGINA PECTORIS; BIOLOGICAL MARKERS; BLOOD PROTEINS; C-REACTIVE PROTEIN; CASE-CONTROL STUDIES; CORONARY ARTERY DISEASE; FEMALE; HUMANS; INTERCELLULAR ADHESION MOLECULE-1; MALE; MIDDLE AGED; MYOCARDIAL INFARCTION; RETROSPECTIVE STUDIES; VASCULAR CELL ADHESION MOLECULE-1; ALPHA-2-HS-GLYCOPROTEIN;

EID: 77954462641     PISSN: 09182918     EISSN: 13497235     Source Type: Journal    
DOI: 10.2169/internalmedicine.49.3223     Document Type: Article

References (23)

1. Ross R. Atherosclerosis-an inflammatory disease. N Engl J Med 340: 115-126, 1999.
2. Nakai K, Itoh C, Kawazoe K, et al. Concentration of soluble vascular cell adhesion molecule-1 (VCAM-1) correlated with expression of VCAM-1 mRNA in the human atherosclerotic aorta. Coron Artery Dis 6: 497-502, 1995.
3. Blann AD, McCollum CN. Circulating endothelial cell/leukocyte adhesion molecules in atherosclerosis. Thromb Haemost 72: 151-154, 1994.
4. Saku K, Zhang B, Ohta T, Shirai K, Tsuchiya Y, Arakawa K. Levels of soluble cell adhesion molecules in patients with angiographically defined coronary atherosclerosis. Jpn Circ J 63: 19-24, 1999.
5. Wang H, Zhang M, Bianchi M, Sherry B, Sama A, Tracey KJ. Fetuin (alpha2-HS-glycoprotein) opsonizes cationic macrophage deactivating molecules. Proc Natl Acad Sci USA 95: 14429-14434, 1998.
6. Demetriou M, Binkert C, Sukhu B, Tenenbaum HC, Dennis JW. Fetuin/alpha2-HS glycoprotein is a transforming growth factor-beta type II receptor mimic and cytokine antagonist. J Biol Chem 271: 12755-12761, 1996.
7. Reynolds JL, Skepper JN, McNair R, et al. Multifunctional roles for serum protein fetuin-A in inhibition of human vascular smooth muscle cell calcification. J Am Soc Nephrol 16: 2920-2930, 2005.
8. Lim P, Collet JP, Moutereau S, et al. Fetuin-A is an independent predictor of death after ST-elevation myocardial infarction. Clin Chem 53: 1835-1840, 2007.
9. Weikert C, Stefan N, Schulze MB, et al. Plasma fetuin-a levels and the risk of myocardial infarction and ischemic stroke. Circulation 118: 2555-2562, 2008.
10. Alpert JS, Thygesen K, Antman E, Bassand JP. Myocardial infarction redefined -a consensus document of the Joint European Society of Cardiology/American College of Cardiology Committee for the Redefinition of Myocardial Infarction. J Am Coll Cardiol 36: 959-969, 2000.
11. Kishore BK, Gejyo F, Arakawa M. Alpha 2HS-glycoprotein in the serum and urine of patients with renal diseases. Postgrad Med J 59: 304-307, 1983.
12. Rittig K, Thamer C, Haupt A, et al. High plasma fetuin-A is associated with increased carotid intima-media thickness in a middle-aged population. Atherosclerosis 207: 341-342, 2009.
13. Ketteler M, Bongartz P, Westenfeld R, et al. Association of low fetuin-A (AHSG) concentrations in serum with cardiovascular mortality in patients on dialysis: a cross-sectional study. Lancet 361: 827-833, 2003.
14. Merx MW, Schafer C, Westenfeld R, et al. Myocardial stiffness, cardiac remodeling, and diastolic dysfunction in calcification-prone fetuin-A-deficient mice. J Am Soc Nephrol 16: 3357-3364, 2005.
15. Ombrellino M, Wang H, Yang H, et al. Fetuin, a negative acute phase protein, attenuates TNF synthesis and the innate inflammatory response to carrageenan. Shock 15: 181-185, 2001.
16. Kelly RA, Smith TW. Cytokines and cardiac contractile function. Circulation 95: 778-781, 1997.
17. Ix JH, Chertow GM, Shlipak MG, Brandenburg VM, Ketteler M, Whooley MA. Association of fetuin-A with mitral annular calcification and aortic stenosis among persons with coronary heart disease: data from the Heart and Soul Study. Circulation 115: 2533-2539, 2007.
18. Blake GJ, Ridker PM. C-reactive protein and other inflammatory risk markers in acute coronary syndromes. J Am Coll Cardiol 41: 37S-42S, 2003.
19. Liuzzo G, Biasucci LM, Gallimore JR, et al. The prognostic value of C-reactive protein and serum amyloid a protein in severe unstable angina. N Engl J Med 331: 417-424, 1994.
20. Lebreton JP, Joisel F, Raoult JP, Lannuzel B, Rogez JP, Humbert G. Serum concentration of human alpha 2 HS glycoprotein during the inflammatory process: evidence that alpha 2 HS glycoprotein is a negative acute-phase reactant. J Clin Invest 64: 1118-1129, 1979.
21. Morisaki N, Saito I, Tamura K, et al. New indices of ischemic heart disease and aging: studies on the serum levels of soluble intercellular adhesion molecule-1 (ICAM-1) and soluble vascular cell adhesion molecule-1 (VCAM-1) in patients with hypercholesterolemia and ischemic heart disease. Atherosclerosis 131: 43-48, 1997.
22. Peter K, Nawroth P, Conradt C, et al. Circulating vascular cell adhesion molecule-1 correlates with the extent of human atherosclerosis in contrast to circulating intercellular adhesion molecule-1, E-selectin, P-selectin, and thrombomodulin. Arterioscler Thromb Vasc Biol 17: 505-512, 1997.
23. Frijns CJ, Kappelle LJ, van Gijn J, Nieuwenhuis HK, Sixma JJ, Fijnheer R. Soluble adhesion molecules reflect endothelial cell activation in ischemic stroke and in carotid atherosclerosis. Stroke 28: 2214-2218, 1997.