A primer for clinical researchers in the emergency department: Part IV: Multicentre research

EMA - Emergency Medicine Australasia

Volumn 24, Issue 5, 2012, Pages 482-491

  Oakley, Ed ^a,b,c   McdTaylor, David ^d,e   Coats, Tim ^h   Davidson, Andrew ^c,e,f   Fry, Amanda ^a   Babl, Franz E ^c,e,g  

^a MONASH MEDICAL CENTRE   (Australia)

^b MONASH UNIVERSITY   (Australia)

^c MURDOCH CHILDREN'S RESEARCH INSTITUTE   (Australia)

^d AUSTIN HOSPITAL   (Australia)

^e UNIVERSITY OF MELBOURNE   (Australia)

^f ROYAL CHILDREN'S HOSPITAL   (Australia)

^g ROYAL CHILDREN'S HOSPITAL   (Australia)

^h UNIVERSITY OF LEICESTER   (United Kingdom)

Author keywords

Emergency department; Multicentre research; Research; Research network

Indexed keywords

AUSTRALIA; CLINICAL PRACTICE; CLINICAL RESEARCH; EMERGENCY CARE; EMERGENCY MEDICINE; EMERGENCY WARD; GOOD CLINICAL PRACTICE; MULTICENTER STUDY (TOPIC); PRIORITY JOURNAL; RESEARCH ETHICS; REVIEW;

AUSTRALIA; BIOMEDICAL RESEARCH; CLINICAL COMPETENCE; COMMUNICATION; COOPERATIVE BEHAVIOR; EMERGENCY SERVICE, HOSPITAL; EVIDENCE-BASED MEDICINE; HEALTH KNOWLEDGE, ATTITUDES, PRACTICE; HUMANS; MULTICENTER STUDIES AS TOPIC; RESEARCH PERSONNEL;

EID: 84867337767     PISSN: 17426731     EISSN: 17426723     Source Type: Journal    
DOI: 10.1111/j.1742-6723.2012.01599.x     Document Type: Review

References (18)

1. National Health and Medical Research Council. Clinical trials. Available from URL: http://www.nhmrc.gov.au/health-ethics/human-research-ethics/clinical-trials [Accessed 30 December 2011].
2. Davidson A, Babl FE. A primer for clinical researchers in the emergency department: part I: ethical and regulatory background. Emerg. Med. Australas. 2010; 22: 399-406.
3. Babl FE, Davidson A. A primer for clinical researchers in the emergency department: part II: research science and conduct. Emerg. Med. Australas. 2010; 22: 407-417.
4. Cook D, Brower R, Cooper J, Brochard L, Vincent JL. Multicentre clinical research in adult critical care. Crit. Care Med. 2002; 30: 1636-1643.
5. Slora EJ, Harris DL, Bocian AB, Wasserman RC. Pediatric clinical research networks: current status, common challenges, and potential solutions. Pediatrics 2010; 126: 740-745.
6. Goodacre S, Coats T, Clancy M. Good clinical practice in clinical trials: core knowledge for emergency physicians. Emerg. Med. J. 2008; 25: 789. doi: 10.1136/emj.2008.063230.
7. Hagen NA, Stiles CR, Biondo PD etal. Establishing a multicentre clinical research network: lessons learned. Curr. Oncol. 2011; 18: e243-249.
8. Irving SY, Curley MAQ. Challenges to conducting multicenter clinical research ten points to consider. AACN Adv. Crit. Care 2008; 19: 164-169.
9. Sectish TC, Starmer AJ, Landrigan CP, Spector ND. Establishing a multisite education and research project requires leadership, expertise, collaboration, and an important aim. Pediatrics 2010; 126: 619-622.
10. Babl FE, Borland M, Ngo P etal. Paediatric Research in Emergency Departments International Collaborative (PREDICT): first steps towards the development of an Australian and New Zealand research network. Emerg. Med. Australas. 2006; 18: 143-147.
11. CRASH-2 trial collaborators. Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial. Lancet 2010; 376 (9734): 23-32.
12. Gray A, Goodacre S, Newby DE, Masson M, Sampson F, Nicholl J, on behalf of the 3CPO trialists. Non invasive ventilation in acute cardiogenic pulmonary edema. N. Engl. J. Med. 2008; 359: 142-151.
13. Bhandari M, Schemitsch EH. Planning a randomized clinical trial: an overview. Tech. Orthop. 2004; 19: 66-71.
14. Lancaster GA, Dodd S, Williamson PR. Design and analysis of pilot studies: recommendations for good practice. J. Eval. Clin. Pract. 2004; 10: 307-312.
15. Oakley E, Babl FE, Acworth J etal. Protocol for the prospective randomised trial comparing nasogastric with intravenous hydration in children with bronchiolitis The comparative rehydration in bronchiolitis study (CRIB). BMC Pediatr. 2010; 10: 37. doi: 10.1186/1471-2431-10-37.
16. Jelinek GA, Mountain D, O'Brien D etal. Re-engineering an Australian Emergency Department: can we measure success? J. Qual. Clin. Pract. 1999; 19: 133-138.
17. Coats T, Goodacre S. Time for D in R&D? J. R. Soc. Med. 2008; 101: 268-269.
18. Carney PA, Geller BM, Moffett H etal. Current medicolegal and confidentiality issues in large, multicenter research programs. Am. J. Epidemiol. 2000; 152: 371-378.