In vivo assessment of retinal neuronal layers in multiple sclerosis with manual and automated optical coherence tomography segmentation techniques

Journal of Neurology

Volumn 259, Issue 10, 2012, Pages 2119-2130

  Seigo, Michaela A ^a   Sotirchos, Elias S ^a   Newsome, Scott ^a   Babiarz, Aleksandra ^a   Eckstein, Christopher ^b   Ford, E'Tona ^a   Oakley, Jonathan D ^c   Syc, Stephanie B ^a   Frohman, Teresa C ^d   Ratchford, John N ^a   Balcer, Laura J ^e   Frohman, Elliot M ^d   Calabresi, Peter A ^a   Saidha, Shiv ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF SOUTH ALABAMA COLLEGE OF MEDICINE   (United States)

^c Voxeleron LLC   (United States)

^d UNIVERSITY OF TEXAS AT DALLAS   (United States)

^e UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Ganglion cell layer; Multiple sclerosis; Optical coherence tomography; Retinal pathology; Retinal segmentation; Visual function

Indexed keywords

ADULT; AGED; ARTICLE; CONTROLLED STUDY; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; MULTIPLE SCLEROSIS; OPTIC NEURITIS; OPTICAL COHERENCE TOMOGRAPHY; PRIORITY JOURNAL; RETINAL LAYER THICKNESS; SENSORY SYSTEM PARAMETERS; VISION; VISUAL ACUITY;

ADULT; AGED; FEMALE; HUMANS; IMAGE INTERPRETATION, COMPUTER-ASSISTED; MALE; MIDDLE AGED; MULTIPLE SCLEROSIS; RETINAL NEURONS; TOMOGRAPHY, OPTICAL COHERENCE; YOUNG ADULT;

EID: 84867336332     PISSN: 03405354     EISSN: 14321459     Source Type: Journal    
DOI: 10.1007/s00415-012-6466-x     Document Type: Article

References (32)

1. Huang D, Swanson EA, Lin CP, Schuman JS, Stinson WG, Chang W, Hee MR, Flotte T, Gregory K, Puliafito CA et al (1991) Optical coherence tomography. Science 254(5035):1178-1181
2. Frohman EM, Fujimoto JG, Frohman TC, Calabresi PA, Cutter G, Balcer LJ (2008) Optical coherence tomography: a window into the mechanisms of multiple sclerosis. Nat Clin Pract Neurol 4(12):664-675
3. Cettomai D, Pulicken M, Gordon-Lipkin E, Salter A, Frohman TC, Conger A, Zhang X, Cutter G, Balcer LJ, Frohman EM, Calabresi PA (2008) Reproducibility of optical coherence tomography in multiple sclerosis. Arch Neurol 65(9):1218-1222
4. Syc SB, Warner CV, Hiremath GS, Farrell SK, Ratchford JN, Conger A, Frohman T, Cutter G, Balcer LJ, Frohman EM, Calabresi PA (2010) Reproducibility of high-resolution optical coherence tomography in multiple sclerosis. Mult Scler 16(7):829-839
5. Chen TC, Cense B, Pierce MC, Nassif N, Park BH, Yun SH, White BR, Bouma BE, Tearney GJ, de Boer JF (2005) Spectral domain optical coherence tomography: ultra-high speed, ultrahigh resolution ophthalmic imaging. Arch Ophthalmol 123(12): 1715-1720
6. Wolf-Schnurrbusch UE, Ceklic L, Brinkmann CK, Iliev ME, Frey M, Rothenbuehler SP, Enzmann V, Wolf S (2009) Macular thickness measurements in healthy eyes using six different optical coherence tomography instruments. Invest Ophthalmol Vis Sci 50(7):3432-3437
7. Balcer LJ (2006) Clinical practice. Optic neuritis. N Engl J Med 354(12):1273-1280
8. Sisto D, Trojano M, Vetrugno M, Trabucco T, Iliceto G, Sborgia C (2005) Subclinical visual involvement in multiple sclerosis: a study by MRI, VEPs, frequency-doubling perimetry, standard perimetry, and contrast sensitivity. Invest Ophthalmol Vis Sci 46(4):1264-1268
9. Toussaint D, Perier O, Verstappen A, Bervoets S (1983) Clinicopathological study of the visual pathways, eyes, and cerebral hemispheres in 32 cases of disseminated sclerosis. J Clin Neuroophthalmol 3(3):211-220
10. Ikuta F, Zimmerman HM (1976) Distribution of plaques in seventy autopsy cases of multiple sclerosis in the United States. Neurology 26(6 PT 2):26-28
11. Shindler KS, Ventura E, Dutt M, Rostami A (2008) Inflammatory demyelination induces axonal injury and retinal ganglion cell apoptosis in experimental optic neuritis. Exp Eye Res 87(3): 208-213
12. Saidha S, Eckstein C, Ratchford JN (2010) Optical coherence tomography as a marker of axonal damage in multiple sclerosis. CML Mult Scler 2(2):33-43
13. Saidha S, Syc SB, Ibrahim MA, Eckstein C, Warner CV, Farrell SK, Oakley JD, Durbin MK, Meyer SA, Balcer LJ, Frohman EM, Rosenzweig JM, Newsome SD, Ratchford JN, Nguyen QD, Calabresi PA (2011) Primary retinal pathology in multiple sclerosis as detected by optical coherence tomography. Brain 134(Pt 2): 518-533
14. Saidha S, Syc SB, Durbin MK, Eckstein C, Oakley JD, Meyer SA, Conger A, Frohman TC, Newsome S, Ratchford JN, Frohman EM, Calabresi PA (2011) Visual dysfunction in multiple sclerosis correlates better with optical coherence tomography derived estimates of macular ganglion cell layer thickness than peripapillary retinal nerve fiber layer thickness. Mult Scler J 17(12):1449-1463
15. Davies EC, Galetta KM, Sackel DJ, Talman LS, Frohman EM, Calabresi PA, Galetta SL, Balcer LJ (2011) Retinal ganglion cell layer volumetric assessment by spectral-domain optical coherence tomography in multiple sclerosis: application of a high-recision manual estimation technique. J Neuroophthalmol 31:260-264
16. Green AJ, McQuaid S, Hauser SL, Allen IV, Lyness R (2010) Ocular pathology in multiple sclerosis: retinal atrophy and inflammation irrespective of disease duration. Brain 133(Pt 6):1591-1601
17. Papakostopoulos D, Fotiou F, Hart JC, Banerji NK (1989) The electroretinogram in multiple sclerosis and demyelinating optic neuritis. Electroencephalogr Clin Neurophysiol 74(1):1-10
18. Forooghian F, Sproule M, Westall C, Gordon L, Jirawuthiworavong G, Shimazaki K, O'Connor P (2006) Electroretinographic abnormalities in multiple sclerosis: possible role for retinal autoantibodies. Doc Ophthalmol 113(2):123-132
19. Polman CH, Reingold SC, Edan G, Filippi M, Hartung HP, Kappos L, Lublin FD, Metz LM, McFarland HF, O'Connor PW, Sandberg-Wollheim M, Thompson AJ, Weinshenker BG, Wolinsky JS (2005) Diagnostic criteria for multiple sclerosis: 2005 revisions to the ''McDonald Criteriá'. Ann Neurol 58(6):840-846
20. Warner CV, Syc SB, Stankiewicz AM, Hiremath G, Farrell SK, Crainiceanu CM, Conger A, Frohman TC, Bisker ER, Balcer LJ, Frohman EM, Calabresi PA, Saidha S (2011) The impact of utilizing different optical coherence tomography devices for clinical purposes and in multiple sclerosis trials. PLoS One 6(8): e22947
21. Hood DC, Lin CE, Lazow MA, Locke KG, Zhang X, Birch DG (2009) Thickness of receptor and post-receptor retinal layers in patients with retinitis pigmentosa measured with frequencydomain optical coherence tomography. Invest Ophthalmol Vis Sci 50(5):2328-2336
22. Hood DC, Cho J, Raza AS, Dale EA, Wang M (2011) Reliability of a computer-aided manual procedure for segmenting optical coherence tomography scans. Optom Vis Sci 88(1):113-123
23. Bland JM, Altman DG (1986) Statistical methods for assessing agreement between two methods of clinical measurement. Lancet 1(8476):307-310
24. Filippi M, van Waesberghe JH, Horsfield MA, Bressi S, Gasperini C, Yousry TA, Gawne-Cain ML, Morrissey SP, Rocca MA, Barkhof F, Lycklama a Nijeholt GJ, Bastianello S, Miller DH (1997) Interscanner variation in brain MRI lesion load measurements in MS: implications for clinical trials. Neurology 49(2):371-377
25. Filippi M, Rocca MA, Gasperini C, Sormani MP, Bastianello S, Horsfield MA, Pozzilli C, Comi G (1999) Interscanner variation in brain MR lesion load measurements in multiple sclerosis using conventional spin-echo, rapid relaxation-enhanced, and fast-FLAIR sequences. Am J Neuroradiol 20(1):133-137
26. Lee J, Koh D, Ong CN (1989) Statistical evaluation of agreement between two methods for measuring a quantitative variable. Comput Biol Med 19(1):61-70
27. Kerrison JB, Flynn T, Green WR (1994) Retinal pathologic changes in multiple sclerosis. Retina 14(5):445-451
28. Balcer LJ, Galetta SL, Calabresi PA, Confavreux C, Giovannoni G, Havrdova E, Hutchinson M, Kappos L, Lublin FD, Miller DH, O'Connor PW, Phillips JT, Polman CH, Radue EW, Rudick RA, Stuart WH, Wajgt A, Weinstock-Guttman B, Wynn DR, Lynn F, Panzara MA (2007) Natalizumab reduces visual loss in patients with relapsing multiple sclerosis. Neurology 68(16):1299-1304
29. Balcer LJ, Frohman EM (2010) Evaluating loss of visual function in multiple sclerosis as measured by low-contrast letter acuity. Neurology 74(Suppl 3):S16-S23
30. Hogan MJ, Alvarado JA, Weddell JE (1971) Histology of the human eye. W. B. Saunders, Philadelphia
31. Talman LS, Bisker ER, Sackel DJ, Long DA Jr, Galetta KM, Ratchford JN, Lile DJ, Farrell SK, Loguidice MJ, Remington G, Conger A, Frohman TC, Jacobs DA, Markowitz CE, Cutter GR, Ying GS, Dai Y, Maguire MG, Galetta SL, Frohman EM, Calabresi PA, Balcer LJ (2010) Longitudinal study of vision and retinal nerve fiber layer thickness in multiple sclerosis. Ann Neurol 67(6):749-760
32. Gordon-Lipkin E, Chodkowski B, Reich DS, Smith SA, Pulicken M, Balcer LJ, Frohman EM, Cutter G, Calabresi PA (2007) Retinal nerve fiber layer is associated with brain atrophy in multiple sclerosis. Neurology 69(16):1603-1609