CXCL12 improves immune responses to neurotropic virus propagation in the CNS by attracting antibody secreting cells

Veterinary Immunology and Immunopathology

Volumn 150, Issue 1-2, 2012, Pages 19-26

  Lee, Hyunkyoung ^a   Sunden, Yuji ^a   Sakai, Yusuke ^a   Ochiai, Kenji ^a   Umemura, Takashi ^a  

^a HOKKAIDO UNIVERSITY   (Japan)

Author keywords

Antibody secreting cells; Chemokine; CXCL12; Neurotropic virus; Pseudorabies virus; Rabies virus

Indexed keywords

STROMAL CELL DERIVED FACTOR 1;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIBODY SECRETING CELL; ARTICLE; CELL KINETICS; CELL MIGRATION; CENTRAL NERVOUS SYSTEM; CHEMOTAXIS; CONTROLLED STUDY; FEMALE; IMMUNE RESPONSE; IMMUNIZATION; IMMUNOCOMPETENT CELL; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; RABIES VIRUS; SURVIVAL RATE;

ANIMALS; ANTIBODY-PRODUCING CELLS; BLOTTING, WESTERN; BRAIN; CHEMOKINE CXCL12; CHEMOTAXIS; FEMALE; HERPESVIRUS 1, SUID; IMMUNOGLOBULINS; IMMUNOHISTOCHEMISTRY; MICE; MICE, INBRED BALB C; MICE, INBRED ICR; PSEUDORABIES; RABIES; RABIES VIRUS; SPECIFIC PATHOGEN-FREE ORGANISMS; STATISTICS, NONPARAMETRIC;

MUS; RABIES VIRUS; SUID HERPESVIRUS 1;

EID: 84867332175     PISSN: 01652427     EISSN: 18732534     Source Type: Journal    
DOI: 10.1016/j.vetimm.2012.08.003     Document Type: Article

References (43)

1. Benner R., Hijmans W., Haaijman J.J. The bone marrow: the major source of serum immunoglobulins, but still a neglected site of antibody formation. Clin. Exp. Immunol. 1981, 46:1-8.
2. Blades M.C., Manzo A., Ingegnoli F., Taylor P.R., Panayi G.S., Irjala H., Jalkanen S., Haskard D.O., Perretti M., Pitzalis C. Stromal cell-derived factor 1 (CXCL12) induces human cell migration into human lymph nodes transplanted into SCID mice. J. Immunol. 2002, 168:4308-4317.
3. Bleul C.C., Schultze J.L., Springer T.A. B lymphocyte chemotaxis regulated in association with microanatomic localization, differentiation state, and B cell receptor engagement. J. Exp. Med. 1998, 187:753-762.
4. Cekinovic D., Golemac M., Pugel E.P., Tomac J., Cicin-Sain L., Slavuljica I., Bradford R., Misch S., Winkler T.H., Mach M., Britt W.J., Jonjic S. Passive immunization reduces murine cytomegalovirus-induced brain pathology in newborn mice. J. Virol. 2008, 82:12172-12180.
5. Diamond M.S., Shrestha B., Marri A., Mahan D., Engle M. B cells and antibody play critical roles in the immediate defense of disseminated infection by West Nile encephalitis virus. J. Virol. 2003, 77:2578-2586.
6. Engelhardt B. Molecular mechanisms involved in T cell migration across the blood-brain barrier. J. Neural Transm. 2006, 113:477-485.
7. Engelhardt B., Ransohoff R.M. The ins and outs of T-lymphocyte trafficking to the CNS: anatomical sites and molecular mechanisms. Trends Immunol. 2005, 26:485-495.
8. Faber M., Li J., Kean R.B., Hooper D.C., Alugupalli K.R., Dietzschold B. Effective preexposure and postexposure prophylaxis of rabies with a highly attenuated recombinant rabies virus. Proc. Natl. Acad. Sci. U.S.A. 2009, 106:11300-11305.
9. Galea I., Bechmann I., Perry V.H. What is immune privilege (not)?. Trends Immunol. 2007, 28:12-18.
10. Han Y.W., Aleyas A.G., George J.A., Kim S.J., Kim H.K., Yoo D.J., Kang S.H., Eo S.K. Genetic co-transfer of CCR7 ligands enhances immunity and prolongs survival against virulent challenge of pseudorabies virus. Immunol. Cell Biol. 2009, 87:91-99.
11. Hara Y., Hasebe R., Sunden Y., Ochiai K., Honda E., Sakoda Y., Umemura T. Propagation of swine hemagglutinating encephalomyelitis virus and pseudorabies virus in dorsal root ganglia cells. J. Vet. Med. Sci. 2009, 71:595-601.
12. Hara Y., Sunden Y., Ochiai K., Umemura T. In vitro propagation of rabies virus in mouse dorsal root ganglia cells. Jpn. J. Vet. Res. 2009, 56:181-188.
13. Hargreaves D.C., Hyman P.L., Lu T.T., Ngo V.N., Bidgol A., Suzuki G., Zou Y.R., Littman D.R., Cyster J.G. A coordinated change in chemokine responsiveness guides plasma cell movements. J. Exp. Med. 2001, 194:45-56.
14. Hauser A.E., Debes G.F., Arce S., Cassese G., Hamann A., Radbruch A., Manz R.A. Chemotactic responsiveness toward ligands for CXCR3 and CXCR4 is regulated on plasma blasts during the time course of a memory immune response. J. Immunol. 2002, 169:1277-1282.
15. Hooper D.C., Phares T.W., Fabis M.J., Roy A. The production of antibody by invading B cells is required for the clearance of rabies virus from the central nervous system. PLoS Negl. Trop. Dis. 2009, 3:e535.
16. Johnson N., Cunningham A.F., Fooks A.R. The immune response to rabies virus infection and vaccination. Vaccine 2010, 28:3896-3901.
17. Koenen R.R., von Hundelshausen P., Nesmelova I.V., Zernecke A., Liehn E.A., Sarabi A., Kramp B.K., Piccinini A.M., Paludan S.R., Kowalska M.A., Kungl A.J., Hackeng T.M., Mayo K.H., Weber C. Disrupting functional interactions between platelet chemokines inhibits atherosclerosis in hyperlipidemic mice. Nat. Med. 2009, 15:97-103.
18. Kohler R.E., Comerford I., Townley S., Haylock-Jacobs S., Clark-Lewis I., McColl S.R. Antagonism of the chemokine receptors CXCR3 and CXCR4 reduces the pathology of experimental autoimmune encephalomyelitis. Brain Pathol. 2008, 18:504-516.
19. Kunkel E.J., Butcher E.C. Plasma-cell homing. Nat. Rev. Immunol. 2003, 3:822-829.
20. Kurtz C.I., Sun X.M., Fujinami R.S. B-lymphocyte requirement for vaccine-mediated protection from Theiler's murine encephalomyelitis virus-induced central nervous system disease. J. Virol. 1995, 69:5152-5155.
21. Lapidot T., Dar A., Kollet O. How do stem cells find their way home?. Blood 2005, 106:1901-1910.
22. Lee H., Sunden Y., Ochiai K., Umemura T. Experimental intracerebral vaccination protects mouse from a neurotropic virus by attracting antibody secreting cells to the CNS. Immunol. Lett. 2011, 139:102-109.
23. Liu K.K., Dorovini-Zis K. Regulation of CXCL12 and CXCR4 expression by human brain endothelial cells and their role in CD4+ and CD8+ T cell adhesion and transendothelial migration. J. Neuroimmunol. 2009, 215:49-64.
24. Manz R.A., Lohning M., Cassese G., Thiel A., Radbruch A. Survival of long-lived plasma cells is independent of antigen. Int. Immunol. 1998, 10:1703-1711.
25. McCandless E.E., Wang Q., Woerner B.M., Harper J.M., Klein R.S. CXCL12 limits inflammation by localizing mononuclear infiltrates to the perivascular space during experimental autoimmune encephalomyelitis. J. Immunol. 2006, 177:8053-8064.
26. Moser K., Muehlinghaus G., Manz R., Mei H., Voigt C., Yoshida T., Dorner T., Hiepe F., Radbruch A. Long-lived plasma cells in immunity and immunopathology. Immunol. Lett. 2006, 103:83-85.
27. Odendahl M., Mei H., Hoyer B.F., Jacobi A.M., Hansen A., Muehlinghaus G., Berek C., Hiepe F., Manz R., Radbruch A., Dorner T. Generation of migratory antigen-specific plasma blasts and mobilization of resident plasma cells in a secondary immune response. Blood 2005, 105:1614-1621.
28. Ostrowski M.A., Justement S.J., Catanzaro A., Hallahan C.A., Ehler L.A., Mizell S.B., Kumar P.N., Mican J.A., Chun T.W., Fauci A.S. Expression of chemokine receptors CXCR4 and CCR5 in HIV-1-infected and uninfected individuals. J. Immunol. 1998, 161:3195-3201.
29. Park M.K., Amichay D., Love P., Wick E., Liao F., Grinberg A., Rabin R.L., Zhang H.H., Gebeyehu S., Wright T.M., Iwasaki A., Weng Y., DeMartino J.A., Elkins K.L., Farber J.M. The CXC chemokine murine monokine induced by IFN-gamma (CXC chemokine ligand 9) is made by APCs, targets lymphocytes including activated B cells, and supports antibody responses to a bacterial pathogen in vivo. J. Immunol. 2002, 169:1433-1443.
30. Phares T.W., Kean R.B., Mikheeva T., Hooper D.C. Regional differences in blood-brain barrier permeability changes and inflammation in the apathogenic clearance of virus from the central nervous system. J. Immunol. 2006, 176:7666-7675.
31. Ransohoff R.M., Kivisakk P., Kidd G. Three or more routes for leukocyte migration into the central nervous system. Nat. Rev. Immunol. 2003, 3:569-581.
32. Roy A., Hooper D.C. Lethal silver-haired bat rabies virus infection can be prevented by opening the blood-brain barrier. J. Virol. 2007, 81:7993-7998.
33. Sellebjerg F., Sorensen T.L. Chemokines and matrix metalloproteinase-9 in leukocyte recruitment to the central nervous system. Brain Res. Bull. 2003, 61:347-355.
34. Slifka M.K., Matloubian M., Ahmed R. Bone marrow is a major site of long-term antibody production after acute viral infection. J. Virol. 1995, 69:1895-1902.
35. Smith K.G., Hewitson T.D., Nossal G.J., Tarlinton D.M. The phenotype and fate of the antibody-forming cells of the splenic foci. Eur. J. Immunol. 1996, 26:444-448.
36. Sze D.M., Toellner K.M., Garcia de Vinuesa C., Taylor D.R., MacLennan I.C. Intrinsic constraint on plasmablast growth and extrinsic limits of plasma cell survival. J. Exp. Med. 2000, 192:813-821.
37. Takahashi H., Yoshikawa Y., Kai C., Yamanouchi K. Mechanism of pruritus and peracute death in mice induced by pseudorabies virus (PRV) infection. J. Vet. Med. Sci. 1993, 55:913-920.
38. Tschen S.I., Stohlman S.A., Ramakrishna C., Hinton D.R., Atkinson R.D., Bergmann C.C. CNS viral infection diverts homing of antibody-secreting cells from lymphoid organs to the CNS. Eur. J. Immunol. 2006, 36:603-612.
39. Ubogu E.E., Cossoy M.B., Ransohoff R.M. The expression and function of chemokines involved in CNS inflammation. Trends Pharmacol. Sci. 2006, 27:48-55.
40. Venetz D., Ponzoni M., Schiraldi M., Ferreri A.J., Bertoni F., Doglioni C., Uguccioni M. Perivascular expression of CXCL9 and CXCL12 in primary central nervous system lymphoma: T-cell infiltration and positioning of malignant B cells. Int. J. Cancer 2010, 127:2300-2312.
41. Wehrli N., Legler D.F., Finke D., Toellner K.M., Loetscher P., Baggiolini M., MacLennan I.C., Acha-Orbea H. Changing responsiveness to chemokines allows medullary plasmablasts to leave lymph nodes. Eur. J. Immunol. 2001, 31:609-616.
42. Willoughby R.E., Tieves K.S., Hoffman G.M., Ghanayem N.S., Amlie-Lefond C.M., Schwabe M.J., Chusid M.J., Rupprecht C.E. Survival after treatment of rabies with induction of coma. N. Engl. J. Med. 2005, 352:2508-2514.
43. Wilson E.H., Weninger W., Hunter C.A. Trafficking of immune cells in the central nervous system. J. Clin. Invest. 2010, 120:1368-1379.