Antioxidant peptides from protein hydrolysate of microalgae navicula incerta and their protective effects in Hepg2/CYP2E1 cells induced by ethanol

Phytotherapy Research

Volumn 26, Issue 10, 2012, Pages 1555-1563

  Kang, Kyong Hwa ^a   Qian, Zhong Ji ^b   Ryu, Bomi ^a   Karadeniz, Fatih ^a   Kim, Daekyung ^c   Kim, Se Kwon ^a  

^a Pukyong National University   (South Korea)

^b Chosun University   (South Korea)

^c Korea Basic Science Institute (KBSI)   (South Korea)

Author keywords

bioactive peptides; HepG2 CYP2E1; liver injury; microalgae; Navicula incerta

Indexed keywords

ALCOHOL; ANTIOXIDANT; CHYMOTRYPSIN A; ENZYME; GAMMA GLUTAMYLTRANSFERASE; GLUTATHIONE; LIVER PROTECTIVE AGENT; NEUTRASE; PAPAIN; PEPSIN A; PEPTIDE NIPP 1; PEPTIDE NIPP 2; PRONASE E; PROTEIN HYDROLYSATE; SUBTILISIN; TRYPSIN; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ANTIOXIDANT ACTIVITY; ARTICLE; CELL CULTURE; CELL VIABILITY; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CYTOTOXICITY; DRUG MECHANISM; ENZYME ACTIVITY; ENZYME PURIFICATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; ION EXCHANGE CHROMATOGRAPHY; LIVER PROTECTION; MICROALGA; MOLECULAR WEIGHT; NAVICULA INCERTA; NONHUMAN; PROTEIN ANALYSIS; PROTEIN DEPLETION; PROTEIN HYDROLYSIS; WESTERN BLOTTING;

ANTIOXIDANTS; CELL SURVIVAL; DIATOMS; ETHANOL; HEP G2 CELLS; HUMANS; MICROALGAE; PEPTIDES; PROTECTIVE AGENTS; PROTEIN HYDROLYSATES;

NAVICULA INCERTA;

EID: 84867329112     PISSN: 0951418X     EISSN: 10991573     Source Type: Journal    
DOI: 10.1002/ptr.4603     Document Type: Article

References (31)

1. Albano E, Tomasi A, Persson JO, et al,. 1991. Role of ethanol-inducible cytochrome P450 (P450IIE1) in catalysing the free radical activation of aliphatic alcohols. Biochem Pharmacol 41: 1895-1902.
2. Anderson ME,. 1985. Determination of glutathione and glutathione disulfide in biological samples. Meth Enzymol 113: 548-555.
3. Borowitzka MA,. 1995. Microalgae as sources of pharmaceuticals and other biologically active compounds. J Appl Phycol 7: 3-15.
4. Burton SG, Cowan DA, Woodley JM,. 2002. The search for the ideal biocatalyst. Nature Biotech 20: 37-45.
5. Chen J, Suetsuna K, Yamauchi F,. 1995. Isolation and characterization of immunostimulativepeptides from soybean. J Nutr Biochem 6: 310-313.
6. Denizot F, Lang R,. 1986. Rapid colorimetric assay for cell growth and survival: Modifications to the tetrazolium dye procedure giving improved sensitivity and reliability. J Immunol Meth 89: 271-277.
7. Felver ME, Mezey E, McGire M, Nathan C,. 1990. Plasma tumor necrosis factor alpha predicts long-term survival in severe alcoholic hepatitis. Alcohol Clin Exp Res 114: 255-259.
8. Friedman SL,. 1993. The cellular basis of hepatic fibrosis-Mechanisms and treatment strategies. N Engl J Med 328: 1828-1835.
9. Han Y, Meng T, Murray NR, Fields AP, Brasier AR,. 1999. Interleukin 1 induced nuclear factor-kappaB-Ikappa-Balpha autoregulatory feedback loop in hepatocytes. A role for protein kinase calpha in post-transcriptional regulatory of ikappabalpha resynthesis. J Biol Chem 274: 939-947.
10. Jung WK, Rajapakse N, Kim SK,. 2005. Antioxidative activity of low molecular peptide derived from the sauce of fermented blue mussel, Mytilus edulis. Eur Food Res Technol 220: 535-539.
11. Kang KH, Qian ZJ, Ryu BM, Kim SK,. 2011. Characterization of growth and protein contents from microalgae Navicula incerta with the investigation of antioxidant activity of enzymatic hydrolysates. Food Sci Biotechnol 20: 183-191.
12. Kim SK, Kim YT, Byun TG, Park PJ, Ito H,. 2001. Purification and characterization of antioxidative peptides from bovine skin. J Biochem Mol Biol 34: 214-219.
13. Kok PJ, Seidel B, Holtkamp KC, Huisman J,. 1978. A new procedure for the visualization of multiple forms of gamma-glutamyl transferase (GGT). Results in normals, patients receiving enzyme-inducing drugs and patients having liver parenchymal lesions. Clin Chim Acta 90: 209-216.
14. Kono H, Arteel GE, Rusyn I, Sies H, Thurman RG,. 2001. Ebselen prevents early alcohol- induced liver injury in rats. Free Radic Biol Med 30: 403-411.
15. Lands WEM,. 1995. Cellular signals in alcohol induced liver injury, a review. Alcohol Clin Exp Res 19: 928-938.
16. Lieber CS,. 1994. Susceptibility to alcohol-related liver injury. Alcohol Alcohol Suppl 2: 315-326.
17. Lupo MP,. 2001. Antioxidants and vitamins in cosmetics. Clin Dermatol 19: 467-473.
18. McClain CJ, Hill DB, Song Z, et al,. 2002. S-Adenosylmethionine, cytokines, and alcoholic liver disease. Alcohol 27: 185-92.
19. Neuman MG, Koren G, Tiribelli C,. 1993. In vitro assessment of the ethanol-induced hepatotoxicity on HepG2 cell line. Biochem Biophys Res Commun 197: 932-41.
20. Neuman MG, Shear NH, Bellentani S, Tiribelli C,. 1998. Role of cytokines in ethanol-induced cytotoxicity in vitro in HepG2 cells. Gastroenterology 115: 157-166.
21. Neuman MG, Cameron RG, Haber JA, Katz GG, Malkiewicz I, Shear NH,. 1999. Inducers of cytochrome P450 2E1 enhance methotrexate-induced hepatotoxicity. Clin Biochem 32: 519-36.
22. Oliveira MAS, Monteiro MP, Robbs PG, Leite SG,. 1999. Growth and chemical composition of Spirulena maxima and Spirulena platensis biomass at different temperatures. Aquacult Int 7: 261-275.
23. Pihlanto LA,. 2001. Bioactive peptides derived from bovine whey proteins: opioid and ACE-inhibitory peptides. Trends Food Sci Technol 11: 347-356.
24. Rashba-Step J, Cederbaum AI,. 1994. Generation of reactive oxygen intermediates by human liver microsomes in the presence of NADPH or NADH. Mol Pharmacol 45: 150-157.
25. Renaud SM, Zhou HC, Parry DL, Loung-Van T, Woo KC,. 1995. Effect of temperature on the growth, total lipid content and fatty acid composition of recently isolated tropical microalgae Isochrysis sp., Nitzschia closterium, Nitzschia paleacea, and commercial species Isochrysis sp., (clone T.ISO). J Appl Phycol 7: 595-602.
26. Sakata K,. 2006. Antioxidants from marine organisms. In Food and Free Radicals, Hiramatsu M, Yoshikawa T, Inoue M, (eds). Springer Publishing: Tokyo; 85-100.
27. Sen CK, Packer L,. 1996. Antioxidant and redox regulation of gene transcription. FASEB J 10: 709-720.
28. Silber PM, Gandolfi AJ, Brendel K,. 1986. Adaptation of a [gamma]-glutamyl transpeptidase assay to microtiter plates. Anal Biochem 158: 68-71.
29. Spolaore P, Joannis-Cassan C, Duran E, Isambert A,. 2006. Commercial applications of microalgae. J Biosci Bioeng 101: 87-96.
30. Suetsuna K, Maekawa K, Chen J,. 2004. Antihypertensive effects of Undaria pinnatifida (wakame) peptide on blood pressure in spontaneously hypertensive rats. J Nutr Biochem 15: 267-272.
31. Tsuruki T, Kishi K, Takahashi M, Tanaka M, Matsukawa T, Yoshikawa M,. 2003. Soymetide, an immunostimulating peptide derived from soybean b-conglycinin, is an Fmlp agonist. FEBS Lett 540: 206-210.