Direct fabrication as a patient-targeted therapeutic in a clinical environment

Methods in Molecular Biology

Volumn 868, Issue , 2012, Pages 327-340

  Hutmacher, Dietmar W ^a   Woodruff, Maria Ann ^a   Shakesheff, Kevin ^b   Guldberg, Robert E ^c  

^a QUEENSLAND UNIVERSITY OF TECHNOLOGY   (Australia)

^b UNIVERSITY OF NOTTINGHAM   (United Kingdom)

^c GEORGIA INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

Composites; Growth factors; Mesenchymal stem cells; Rapid prototyping; Scaffolds; Tissue engineering

Indexed keywords

CYTOKINE; GROWTH FACTOR; TISSUE SCAFFOLD; SIGNAL PEPTIDE;

ARTICLE; BONE; BONE REGENERATION; CELL ADHESION; CELL SURVIVAL; HUMAN; MESENCHYMAL STEM CELL; NANOFABRICATION; NONHUMAN; OSSIFICATION; POROSITY; PRIORITY JOURNAL; REPRODUCIBILITY; TISSUE ENGINEERING; WOUND HEALING; ANIMAL; BONE DEVELOPMENT; BONE PROSTHESIS; CHEMISTRY; CYTOLOGY; METABOLISM; METHODOLOGY; SWINE; ULTRASTRUCTURE;

ANIMALS; BONE AND BONES; BONE SUBSTITUTES; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MESENCHYMAL STEM CELLS; OSTEOGENESIS; SWINE; TISSUE ENGINEERING; TISSUE SCAFFOLDS;

EID: 84867292197     PISSN: 10643745     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-61779-764-4_20     Document Type: Article

References (37)

1. Hutmacher DW, Cool S (2007) Concepts of scaffold-based tissue engineering-The rationale to use solid free-form fabrication techniques. J Cell Mol Med 11(4):654-669
2. Lam CXF, Teoh SH, Hutmacher DW (2007) Comparison of degradation of PCL and PCLTCP scaffolds in alkaline medium. Polym Int 6:718-728
3. Vacanti CA (2006) The history of tissue engineering. J Cell Mol Med 10:569-576
4. Hutmacher DW, Sittinger M, Risbud MV (2004) Scaffold-based tissue engineering: rationale for computer-aided design and solid free-form fabrication systems. Trends Biotechnol 22:354-362
5. Bach AD, Arkudas A, Tjiawi J, Polykandriotis E, Kneser U, Horch RE, Beier JP (2006) A new approach to tissue engineering of vascularized skeletal muscle. J Cell MolMed 10:716-726
6. Kneser U, Stangenberg L, Ohnolz J, Buettner O, Stern-Straeter J,MobestD,Horch RE, Stark GB, SchaeferDJ (2006) Evaluation of processed bovine cancellous bone matrix seeded with syngenic osteoblasts in a critical size calvarial defect rat model. J Cell Mol Med 10:695-670
7. Zhou Y, Chen F, Ho ST, Woodruff MA, Lim TM, Hutmacher DW (2007) Combined marrow stromal cell-sheet techniques and highstrength biodegradable composite scaffolds for engineered functional bone grafts. Biomaterials 28:814-824
8. Hollister SJ (2005) Porous scaffold design for tissue engineering. Nat Mater 4:518-524
9. Oest ME, Dupont KM, Kong H-J, Mooney DJ, Guldberg RE (2005) Quantitative assessment of scaffold and growth factor-mediated repair of critically sized bone defects. J Orthop Res 17415756 (P,S,E,B,D)
10. Rai B, Teoh SH, Hutmacher DW, Cao T, Ho KH (2005) Novel PCL-based honeycomb scaffolds as drug delivery systems for rhBMP-2. Biomaterials 26:3739-3748
11. Suciati T, Howard D, Barry J et al (2006) Zonal release of proteins within tissue engineering scaffolds J Mater Sci Mater Med 17 (11):1049-1056
12. Kanczler JM, Barry J, Ginty P et al (2007) Supercritical carbon dioxide generated vascular endothelial growth factor encapsulated poly (DL-lactic acid) scaffolds induce angiogenesis in vitro. Biochem Biophys Res Commun 352:135-141
13. Kain MS, Einhorn TA (2005) Recombinant human bone morphogenetic proteins in the treatment of fractures. Foot Ankle Clin 10:639-650, viii
14. Govender S, Csimma C, Genant HK, Valentin-Opran A, Amit Y, Arbel R, Aro H, Atar D, Bishay M, Borner MG, Chiron P, Choong P, Cinats J, Courtenay B, Feibel R, Geulette B, Gravel C, Haas N, Raschke M, Hammacher E, van der Velde D, Hardy P, Holt M, Josten C, Ketterl RL, Lindeque B, Lob G, Mathevon H, McCoy G, Marsh D, Miller R, Munting E, Oevre S, Nordsletten L, Patel A, Pohl A, Rennie W, Reynders P, Rommens PM, Rondia J, Rossouw WC, Daneel PJ, Ruff S, Ruter A, Santavirta S, Schildhauer TA, Gekle C, Schnettler R, Segal D, Seiler H, Snowdowne RB, Stapert J, Taglang G, Verdonk R, Vogels L, Weckbach A, Wentzensen A,Wisniewski T (2002) Recombinant human bone morphogenetic protein-2 for treatment of open tibial fractures: a prospective, controlled, randomized study of four hundred and fifty patients. J Bone Joint Surg Am 84-A:2123-2134
15. De Long WG, Jr., Einhorn TA, Koval K, McKee M, Smith W, Sanders R, Watson T (2007) Bone grafts and bone graft substitutes in orthopaedic trauma surgery. A critical analysis. J Bone Joint Surg Am 89:649-658
16. Hutmacher DW, Woodruff MA (2008) Design, fabrication and characterisation of scaffolds via solid free form fabrication techniques. In: Chu PK, Liu X (eds) Handbook of fabrication and processing of biomaterials. CRC Press/Taylor and Francis Group, pp 45-68
17. Hutmacher, Dietmar W, Woodruff, Maria A (2007) Composite scaffolds for bone engineering. In: Fakirov S, Bhattacharyya D (eds) Handbook of engineering biopolymers: homopolymers, blends and composites. Hanser Gardner, Germany,Munich, pp 773-798
18. Schantz JT, Lim TC, Ning C, Teoh SH, Tan KC, Wang SC, Hutmacher DW (2006) Cranioplasty after trephination using a novel biodegradable burr hole cover: technical case report. Neurosurgery 58:ONS-E176; discussion ONS-E176
19. Zhou YF, Sae-Lim V, Chou AM, Hutmacher DW, Lim TM (2006) Does seeding density affect in vitro mineral nodules formation in novel composite scaffolds? J Biomed Mater Res A 78:183-193
20. Mohan S, Baylink DJ (1991) Bone growth factors. Clin Orthop Relat Res 263:30-48
21. Hutmacher DW, Garcia AJ (2005) Scaffoldbased bone engineering but using genetically modified cells. Gene 347:1-10
22. Cuevas P, de Paz V, Cuevas B, Marin-Martinez J, Picon-Molina M, Fernandez-Pereira A, Gimenez-Gallego G (1997) Osteopromotion for cranioplasty: an experimental study in rats using acidic fibroblast growth factor. Surg Neurol 47:242-246
23. Tabata Y (2008) Current status of regenerative medical therapy based on drug delivery technology. Reprod Biomed Online 16(1):70-80
24. Gruber R, Koch H, Doll BA, Tegtmeier F, Einhorn TA, Hollinger JO (2006) Fracture healing in the elderly patient. Exp Gerontol 41(11):1080-1093
25. SSIB, AREJ (2004) Bone defect repair in rat tibia by TGF-beta1 and IGF-1 released from hydrogel scaffold. Cell Tissue Bank 5:223-230.136
26. Giannoudis PV, Einhorn TA, Marsh D (2007) Fracture healing: the diamond concept. Injury 38(Suppl 4):S3-S6
27. S, Ryder J, Shemilt I, Mugford M, Harvey I, Song F (2007) Clinical effectiveness and costeffectiveness of bone morphogenetic proteins in the non-healing of fractures and spinal fusion: a systematic review. Health Technol Assess 11(30):1-150, iii-iv
28. Robinson Y, Heyde CE, Tschoke SK, Mont MA, Seyler TM, Ulrich SD (2008) Evidence supporting the use of bone morphogenetic proteins for spinal fusion surgery. Expert Rev Med Devices 5(1):75-84
29. Shakesheff KM, France RM, Quirk RA Porous matrix, inventors. International Patent WO200 4084968-A1, GB2415142-A, EP1605984-A1, Regentec LTD
30. Pratoomsoot C et al (2008) A thermoreversible hydrogel as a biosynthetic bandage for corneal wound repair. Biomaterials 29(3): 272-281
31. Howdle SM, Watson MS, Whitaker MJ, Popov VK, Davies MC, Mandel FS, Don WJ, Shakesheff KM et al (2001) Supercritical fluid mixing: preparation of thermally sensitive polymer composites containing bioactive materials. Chem Commun 1:109-110
32. Whitaker MJ et al (2005) The production of protein-loaded microparticles by supercritical fluid enhanced mixing and spraying. J Control Release 101(1-3):85-92
33. Suciati T, Daniel H, Barry J, Everitt N, Shakesheff K, Rose F (2006) Zonal release of proteins within tissue engineering scaffolds. J Mater Sci Mater Med 17:1049
34. Kanczler JM et al (2007) Supercritical carbon dioxide generated vascular endothelial growth factor encapsulated poly(DL-lactic acid) scaffolds induce angiogenesis in vitro. Biochem Biophys Res Commun 352(1):135-141
35. Oest ME, Dupont KM, Kong HJ, Mooney DJ, Guldberg RE (2007) Quantitative assessment of scaffold and growth factor mediated repair of critically-sized bone defects. J Orthop Res 25(7):941-950
36. Rai B, Oest ME, Dupont KM, Ho KH, Teoh SH, Guldberg RE (2007) Combination of platelet rich plasma with polycaprolactone-tricalcium phosphate scaffolds for segmental bone defect repair. J Biomed Mater Res 81 (4):888-899
37. Peng H et al (2005) Synergistic enhancement of bone formation and healing by stem cellexpressed VEGF and bone morphogenetic protein-J Bone Miner Res 20:2017