Fractional excretion of urea to differentiate transient from persistent acute kidney injury: Should we still trust old tools in the biomarker era?

Journal of Critical Care

Volumn 27, Issue 5, 2012, Pages 514-515

  Honoré, Patrick M ^a   Jacobs, Rita ^a   Joannes Boyau, Olivier ^b   Boer, Willem ^c   De Waele, Elisabeth ^a   Van Gorp, Viola ^a   Spapen, Herbert D ^a  

^a UNIVERSITY HOSPITAL BRUSSELS   (Belgium)

^b HAUT LÉVÊQUE HOSPITAL   (France)

^c DEPARTMENT OF CARDIOLOGY   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

CREATININE; DIURETIC AGENT; NEUTROPHIL GELATINASE ASSOCIATED LIPOCALIN; UREA; VASOACTIVE AGENT;

ACUTE KIDNEY FAILURE; ACUTE KIDNEY TUBULE NECROSIS; CONTINUOUS RENAL REPLACEMENT THERAPY; CREATININE BLOOD LEVEL; CRITICALLY ILL PATIENT; EDITORIAL; FRACTIONAL EXCRETION OF UREA; GLOMERULUS FILTRATION RATE; INTENSIVE CARE; PERSISTENT ACUTE KIDNEY FAILURE; PROGNOSIS; RENAL SYSTEM PARAMETERS; SENSITIVITY AND SPECIFICITY; SEPSIS; TRANSIENT ACUTE KIDNEY FAILURE; UREMIA; URINALYSIS;

ACUTE KIDNEY INJURY; FEMALE; HUMANS; INTENSIVE CARE UNITS; MALE; UREA;

EID: 84867289683     PISSN: 08839441     EISSN: 15578615     Source Type: Journal    
DOI: 10.1016/j.jcrc.2012.07.017     Document Type: Editorial

References (25)

1. Wan L., Bagshaw S.M., Langenberg C., et al. Pathophysiology of septic acute kidney injury: what do we really know?. Crit Care Med 2008, 36:S198-S203.
2. Langenberg C., Wan L., Egi M., et al. Renal blood flow and function during recovery from experimental septic acute kidney injury. Intensive Care Med 2007, 33:1614-1618.
3. Legrand M., Mik E.G., Balestra G.M., et al. Fluid resuscitation does not improve renal oxygenation during hemorrhagic shock in rats. Anesthesiology 2010, 112:119-127.
4. Lerolle N., Nochy D., Guerot E., et al. Histopathology of septic shock induced acute kidney injury: apoptosis and leukocytic infiltration. Intensive Care Med 2010, 36:471-478.
5. Jacobs R., Honore P.M., Joannes-Boyau O., et al. Septic acute kidney injury: the culprit is inflammatory apoptosis rather than ischemic necrosis. Blood Purif 2011, 29:262-265.
6. Payen D., Legrand M. Can we identify pre-renal physiology and does it matter?. Contrib Nephrol 2011, 174:22-32.
7. Bellomo R., Bagshaw S., Langenberg C., Ronco C. Pre-renal azotemia: a flawed paradigm in critically ill septic patients?. Contrib Nephrol 2007, 156:1-9.
8. Carvounis C.P., Nisar S., Guro-Razuman S. Significance of the fractional excretion of urea in the differential diagnosis of acute renal failure. Kidney Int 2002, 62:2223-2229.
9. Bagshaw S.M., Langenberg C., Bellomo R. Urinary biochemistry and microscopy in septic acute renal failure: a systematic review. Am J Kidney Dis 2006, 48:695-705.
10. Darmon M., Vincent F., Dellamonica J., et al. Diagnostic performance of fractional excretion of urea in the evaluation of critically ill patients with acute kidney injury: a multicenter cohort study. Crit Care 2011, 15:R178.
11. Pepin M.N., Bouchard J., Legault L., et al. Diagnostic performance of fractional excretion of urea and fractional excretion of sodium in the evaluations of patients with acute kidney injury with or without diuretic treatment. Am J Kidney Dis 2007, 50:566-573.
12. Honore P.M., Joannes-Boyau O., Boer W., Rose T. Real time non-invasive follow-up of acid-base correction by the kidney : a step closer. Minerva Anestesiol 2010, 76:307-309.
13. Dewitte A., Biais M., Petit L., et al. Fractional excretion of urea as a diagnostic index in acute kidney injury in intensive care patients. J Crit Care 2012, 27:505-510.
14. Bagshaw S.M. Subclinical acute kidney injury: a novel biomarker-defined syndrome. Crit Care Resusc 2011, 13:201-203.
15. Haase M., Devarajan P., Haase-Fielitz A., et al. The outcome of neutrophil gelatinase-associated lipocalin-positive subclinical acute kidney injury: a multicenter pooled analysis of prospective studies. J Am Coll Cardiol 2011, 57:1752-1761.
16. Himmelfarb J., Joannidis M., Molitoris B., et al. Evaluation and initial management of acute kidney injury. Clin J Am Soc Nephrol 2008, 3:962-967.
17. Schiffl H., Lang S.M. Update on biomarkers of acute kidney injury: moving closer to clinical impact?. Mol Diagn Ther 2012, Epub ahead of print.
18. Honore P.M., Jacobs R., Joannes-Boyau O., et al. New developments in the detection of early acute kidney injury. Ann Intensive Care 2011, 2:24.
19. Parikh C.R., Coca S.G., Thiessen-Philbrook H., et al. Postoperative biomarkers predict acute kidney injury and poor outcomes after adult cardiac surgery. J Am Soc Nephrol 2011, 22:1748-1757.
20. Ronco C., Kellum J.A., Haase M. Subclinical AKI is still AKI. Crit Care 2012, 16:313.
21. Haase-Fielitz A., Bellomo R., Devarajan P., et al. Novel and conventional serum biomarkers predicting acute kidney injury in adult cardiac surgery-a prospective cohort study. Crit Care Med 2009, 37:553-560.
22. Bennett M., Dent C.L., Ma Q., et al. Urine NGAL predicts severity of acute kidney injury after cardiac surgery : a prospective study. Clin J Am Soc Nephrol 2008, 3:665-673.
23. Shapiro N.I., Trzeciak S., Hollander J.E., et al. The diagnostic accuracy of plasma neutrophil gelatinase-associated lipocalin in the prediction of acute kidney injury in emergency department patients with suspected sepsis. Ann Emerg Med 2010, 56:52-59.
24. Glassford N.J., Bellomo R. Acute kidney injury: how can we facilitate recovery?. Curr Opin Crit Care 2011, 17:562-568.
25. Devarajan P. Review: neutrophil gelatinase-associated lipocalin: a troponin-like biomarker for human acute kidney injury. Nephrology 2010, 15:419-428.