Fast association and slow transitions in the interaction between two intrinsically disordered protein domains

Journal of Biological Chemistry

Volumn 287, Issue 41, 2012, Pages 34316-34324

  Dogan, Jakob ^a   Schmidt, Tanja ^a   Mu, Xin ^a   Engström, Åke ^a   Jemth, Per ^a  

^a UPPSALA UNIVERSITY   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATION DOMAIN; ASSOCIATION RATE CONSTANTS; BINDING DOMAIN; BINDING REACTIONS; CONFORMATIONAL TRANSITIONS; CREB BINDING PROTEINS; DISORDERED PROTEINS; DISORDERED REGIONS; EXPERIMENTAL INVESTIGATIONS; FREE STATE; HIGH SALT CONCENTRATION; INDUCED-FIT MECHANISM; INTERACTION KINETICS; INTERMEDIATE STATE; KINETIC PHASE; PROTEIN DOMAINS; SALT BRIDGES; STOPPED-FLOW TECHNIQUES; THYROID HORMONES; TRANSCRIPTIONAL CO-ACTIVATORS;

CHEMICAL ACTIVATION; KINETICS; PROTEINS; RATE CONSTANTS;

ASSOCIATION REACTIONS;

CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN BINDING PROTEIN; MUTANT PROTEIN; SODIUM CHLORIDE; STEROID RECEPTOR COACTIVATOR 3;

ARTICLE; CHEMICAL REACTION KINETICS; COMPLEX FORMATION; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; INTRINSICALLY DISORDERED PROTEIN DOMAIN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN FOLDING; PROTEIN MODIFICATION; PROTEIN PROTEIN INTERACTION; REACTION TIME; SPECTROMETRY; STATIC ELECTRICITY; STOPPED FLOW SPECTROMETRY;

CREB-BINDING PROTEIN; KINETICS; MODELS, CHEMICAL; MUTATION, MISSENSE; NUCLEAR RECEPTOR COACTIVATOR 3; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY;

EID: 84867280715     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.399436     Document Type: Article

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