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Volumn 423, Issue 4, 2012, Pages 475-481

AIMP3/p18 controls translational initiation by mediating the delivery of charged initiator tRNA to initiation complex

Author keywords

AIMP3; eukaryotic initiation factor 2 subunit (eIF2 ); initiator tRNA; methionine; translation initiation

Indexed keywords

AMINO ACID TRANSFER RNA LIGASE; AMINOACYL TRNA SYNTHETASE INTERACTING MULTIFUNCTIONAL PROTEIN 3 P18; INITIATION FACTOR 2; MEMBRANE PROTEIN; METHIONINE TRANSFER RNA LIGASE; PROTEIN P18; TRANSFER RNA; UNCLASSIFIED DRUG;

EID: 84867263450     PISSN: 00222836     EISSN: 10898638     Source Type: Journal    
DOI: 10.1016/j.jmb.2012.07.020     Document Type: Article
Times cited : (34)

References (27)
  • 1
    • 25144489447 scopus 로고    scopus 로고
    • Functional expansion of aminoacyl-tRNA synthetases and their interacting factors: New perspectives on housekeepers
    • S.G. Park, K.L. Ewalt, and S. Kim Functional expansion of aminoacyl-tRNA synthetases and their interacting factors: new perspectives on housekeepers Trends Biochem. Sci. 30 2005 569 574
    • (2005) Trends Biochem. Sci. , vol.30 , pp. 569-574
    • Park, S.G.1    Ewalt, K.L.2    Kim, S.3
  • 2
    • 77951139250 scopus 로고    scopus 로고
    • Aminoacyl-tRNA synthetase-interacting multifunctional proteins (AIMPs): A triad for cellular homeostasis
    • S.G. Park, E.C. Choi, and S. Kim Aminoacyl-tRNA synthetase-interacting multifunctional proteins (AIMPs): a triad for cellular homeostasis IUBMB Life 62 2010 296 302
    • (2010) IUBMB Life , vol.62 , pp. 296-302
    • Park, S.G.1    Choi, E.C.2    Kim, S.3
  • 3
    • 33846016966 scopus 로고    scopus 로고
    • Hierarchical network between the components of the multi-tRNA synthetase complex: Implications for complex formation
    • J.M. Han, M.J. Lee, S.G. Park, S.H. Lee, E. Razin, E.C. Choi, and S. Kim Hierarchical network between the components of the multi-tRNA synthetase complex: implications for complex formation J. Biol. Chem. 281 2006 38663 38667
    • (2006) J. Biol. Chem. , vol.281 , pp. 38663-38667
    • Han, J.M.1    Lee, M.J.2    Park, S.G.3    Lee, S.H.4    Razin, E.5    Choi, E.C.6    Kim, S.7
  • 4
    • 0035933792 scopus 로고    scopus 로고
    • A cofactor of tRNA synthetase, p43, is secreted to up-regulate proinflammatory genes
    • Y.G. Ko, H. Park, T. Kim, J.W. Lee, S.G. Park, and W. Seol A cofactor of tRNA synthetase, p43, is secreted to up-regulate proinflammatory genes J. Biol. Chem. 276 2001 23028 23033
    • (2001) J. Biol. Chem. , vol.276 , pp. 23028-23033
    • Ko, Y.G.1    Park, H.2    Kim, T.3    Lee, J.W.4    Park, S.G.5    Seol, W.6
  • 5
    • 0037160096 scopus 로고    scopus 로고
    • Dose-dependent biphasic activity of tRNA synthetase-associating factor, p43, in angiogenesis
    • S.G. Park, Y.S. Kang, Y.H. Ahn, S.H. Lee, K.R. Kim, and K.W. Kim Dose-dependent biphasic activity of tRNA synthetase-associating factor, p43, in angiogenesis J. Biol. Chem. 277 2002 45243 45248
    • (2002) J. Biol. Chem. , vol.277 , pp. 45243-45248
    • Park, S.G.1    Kang, Y.S.2    Ahn, Y.H.3    Lee, S.H.4    Kim, K.R.5    Kim, K.W.6
  • 6
    • 13244272361 scopus 로고    scopus 로고
    • The novel cytokine p43 stimulates dermal fibroblast proliferation and wound repair
    • S.G. Park, H. Shin, Y.K. Shin, Y. Lee, E.C. Choi, B.J. Park, and S. Kim The novel cytokine p43 stimulates dermal fibroblast proliferation and wound repair Am. J. Pathol. 166 2005 387 398
    • (2005) Am. J. Pathol. , vol.166 , pp. 387-398
    • Park, S.G.1    Shin, H.2    Shin, Y.K.3    Lee, Y.4    Choi, E.C.5    Park, B.J.6    Kim, S.7
  • 8
    • 0037743658 scopus 로고    scopus 로고
    • Downregulation of FUSE-binding protein and c-myc by tRNA synthetase cofactor p38 is required for lung cell differentiation
    • M.J. Kim, B.J. Park, Y.S. Kang, H.J. Kim, J.H. Park, and J.W. Kang Downregulation of FUSE-binding protein and c-myc by tRNA synthetase cofactor p38 is required for lung cell differentiation Nat. Genet. 34 2003 330 336
    • (2003) Nat. Genet. , vol.34 , pp. 330-336
    • Kim, M.J.1    Park, B.J.2    Kang, Y.S.3    Kim, H.J.4    Park, J.H.5    Kang, J.W.6
  • 9
    • 49649116700 scopus 로고    scopus 로고
    • AIMP2/p38, the scaffold for the multi-tRNA synthetase complex, responds to genotoxic stresses via p53
    • J.M. Han, B.J. Park, S.G. Park, Y.S. Oh, S.J. Choi, and S.W. Lee AIMP2/p38, the scaffold for the multi-tRNA synthetase complex, responds to genotoxic stresses via p53 Proc. Natl Acad. Sci. USA 105 2008 11206 11211
    • (2008) Proc. Natl Acad. Sci. USA , vol.105 , pp. 11206-11211
    • Han, J.M.1    Park, B.J.2    Park, S.G.3    Oh, Y.S.4    Choi, S.J.5    Lee, S.W.6
  • 10
    • 69549096270 scopus 로고    scopus 로고
    • AIMP2 promotes TNFα-dependent apoptosis via ubiquitin-mediated degradation of TRAF2
    • J.W. Choi, D.G. Kim, M.C. Park, J.Y. Um, J.M. Han, and S.G. Park AIMP2 promotes TNFα-dependent apoptosis via ubiquitin-mediated degradation of TRAF2 J. Cell Sci. 122 2009 2710 2715
    • (2009) J. Cell Sci. , vol.122 , pp. 2710-2715
    • Choi, J.W.1    Kim, D.G.2    Park, M.C.3    Um, J.Y.4    Han, J.M.5    Park, S.G.6
  • 11
    • 79953766254 scopus 로고    scopus 로고
    • Cancer-associated splicing variant of tumor suppressor AIMP2/p38: Pathological implication in tumorigenesis
    • J.W. Choi, D.G. Kim, A.E. Lee, H.R. Kim, J.Y. Lee, and N.H. Kwon Cancer-associated splicing variant of tumor suppressor AIMP2/p38: pathological implication in tumorigenesis PLoS Genet. 7 2011 e1001351
    • (2011) PLoS Genet. , vol.7 , pp. 1001351
    • Choi, J.W.1    Kim, D.G.2    Lee, A.E.3    Kim, H.R.4    Lee, J.Y.5    Kwon, N.H.6
  • 12
    • 19944431746 scopus 로고    scopus 로고
    • The haploinsufficient tumor suppressor p18 upregulates p53 via interactions with ATM/ATR
    • B.J. Park, J.W. Kang, S.W. Lee, S.J. Choi, Y.K. Shin, and Y.H. Ahn The haploinsufficient tumor suppressor p18 upregulates p53 via interactions with ATM/ATR Cell 120 2005 209 221
    • (2005) Cell , vol.120 , pp. 209-221
    • Park, B.J.1    Kang, J.W.2    Lee, S.W.3    Choi, S.J.4    Shin, Y.K.5    Ahn, Y.H.6
  • 13
    • 33746872495 scopus 로고    scopus 로고
    • AIMP3 haploinsufficiency disrupts oncogene-induced p53 activation and genomic stability
    • B.J. Park, Y.S. Oh, S.Y. Park, S.J. Choi, C. Rudolph, B. Schlegelberger, and S. Kim AIMP3 haploinsufficiency disrupts oncogene-induced p53 activation and genomic stability Cancer Res. 66 2006 6913 6918
    • (2006) Cancer Res. , vol.66 , pp. 6913-6918
    • Park, B.J.1    Oh, Y.S.2    Park, S.Y.3    Choi, S.J.4    Rudolph, C.5    Schlegelberger, B.6    Kim, S.7
  • 14
    • 78349290448 scopus 로고    scopus 로고
    • Downregulation of lamin A by tumor suppressor AIMP3/p18 leads to a progeroid phenotype in mice
    • Y.S. Oh, D.G. Kim, G. Kim, E.C. Choi, B.K. Kennedy, and Y. Suh Downregulation of lamin A by tumor suppressor AIMP3/p18 leads to a progeroid phenotype in mice Aging Cell 9 2010 810 822
    • (2010) Aging Cell , vol.9 , pp. 810-822
    • Oh, Y.S.1    Kim, D.G.2    Kim, G.3    Choi, E.C.4    Kennedy, B.K.5    Suh, Y.6
  • 15
    • 0029790980 scopus 로고    scopus 로고
    • The yeast protein Arc1p binds to tRNA and functions as a cofactor for the methionyl- and glutamyl-tRNA synthetases
    • G. Simos, A. Seqref, F. Fasiolo, K. Hellmuth, A. Shevchenko, M. Mann, and E.C. Hurt The yeast protein Arc1p binds to tRNA and functions as a cofactor for the methionyl- and glutamyl-tRNA synthetases EMBO J. 15 1996 5437 5448
    • (1996) EMBO J. , vol.15 , pp. 5437-5448
    • Simos, G.1    Seqref, A.2    Fasiolo, F.3    Hellmuth, K.4    Shevchenko, A.5    Mann, M.6    Hurt, E.C.7
  • 17
    • 0000666250 scopus 로고    scopus 로고
    • Precursor of pro-apoptotic cytokine modulates aminoacylation activity of tRNA synthetase
    • S.G. Park, K.H. Jung, J.S. Lee, Y.J. Jo, H. Motegi, S. Kim, and K. Shiba Precursor of pro-apoptotic cytokine modulates aminoacylation activity of tRNA synthetase J. Biol. Chem. 274 1999 16673 16676
    • (1999) J. Biol. Chem. , vol.274 , pp. 16673-16676
    • Park, S.G.1    Jung, K.H.2    Lee, J.S.3    Jo, Y.J.4    Motegi, H.5    Kim, S.6    Shiba, K.7
  • 18
    • 0030583549 scopus 로고    scopus 로고
    • The p18 component of the multisynthetase complex shares a protein motif with the β and γ subunits of eukaryotic elongation factor 1
    • S. Quevillon, and M. Mirande The p18 component of the multisynthetase complex shares a protein motif with the β and γ subunits of eukaryotic elongation factor 1 FEBS Lett. 395 1996 63 67
    • (1996) FEBS Lett. , vol.395 , pp. 63-67
    • Quevillon, S.1    Mirande, M.2
  • 19
    • 83755207354 scopus 로고    scopus 로고
    • Dual role of methionyl-tRNA synthetase in the regulation of translation and tumor suppressor activity of aminoacyl-tRNA synthetase-interacting multifunctional protein-3
    • N.H. Kwon, T. Kang, J.Y. Lee, H.H. Kim, H.R. Kim, and J. Hong Dual role of methionyl-tRNA synthetase in the regulation of translation and tumor suppressor activity of aminoacyl-tRNA synthetase-interacting multifunctional protein-3 Proc. Natl Acad. Sci. USA 108 2011 19635 19640
    • (2011) Proc. Natl Acad. Sci. USA , vol.108 , pp. 19635-19640
    • Kwon, N.H.1    Kang, T.2    Lee, J.Y.3    Kim, H.H.4    Kim, H.R.5    Hong, J.6
  • 20
    • 60149091189 scopus 로고    scopus 로고
    • Regulation of translation initiation in eukaryotes: Mechanisms and biological targets
    • N. Sonnenberg, and A.G. Hinnebusch Regulation of translation initiation in eukaryotes: mechanisms and biological targets Cell 136 2009 731 745
    • (2009) Cell , vol.136 , pp. 731-745
    • Sonnenberg, N.1    Hinnebusch, A.G.2
  • 21
    • 56049116948 scopus 로고    scopus 로고
    • Expression of histone H3 tails with combinatorial lysine modifications under the reprogrammed genetic code for the investigation on epigenetic markers
    • T.J. Kang, S. Yuzawa, and H. Suga Expression of histone H3 tails with combinatorial lysine modifications under the reprogrammed genetic code for the investigation on epigenetic markers Chem. Biol. 15 2008 1166 1174
    • (2008) Chem. Biol. , vol.15 , pp. 1166-1174
    • Kang, T.J.1    Yuzawa, S.2    Suga, H.3
  • 22
    • 0029666095 scopus 로고    scopus 로고
    • The A1-U72 base pair conserved in eukaryotic initiator tRNAs is important specifically for binding to the eukaryotic translation initiation factor eIF2
    • D. Farruggio, J. Chaudhuri, U. Maitra, and U.L. RajBhandary The A1-U72 base pair conserved in eukaryotic initiator tRNAs is important specifically for binding to the eukaryotic translation initiation factor eIF2 Mol. Cell. Biol. 16 1996 4248 4256
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 4248-4256
    • Farruggio, D.1    Chaudhuri, J.2    Maitra, U.3    Rajbhandary, U.L.4
  • 23
    • 0347123543 scopus 로고    scopus 로고
    • GTP-dependent recognition of the methionine moiety on initiator tRNA by translation factor eIF2
    • L.D. Kapp, and J.R. Lorsch GTP-dependent recognition of the methionine moiety on initiator tRNA by translation factor eIF2 J. Mol. Biol. 335 2004 923 936
    • (2004) J. Mol. Biol. , vol.335 , pp. 923-936
    • Kapp, L.D.1    Lorsch, J.R.2
  • 24
    • 0029096171 scopus 로고
    • Mutation in the NKXD consensus element indicate that GTP binds to the γ-subunit of translation initiation factor eIF2
    • T. Naranda, I. Sirangelo, B.J. Fabbri, and J.W. Hershey Mutation in the NKXD consensus element indicate that GTP binds to the γ-subunit of translation initiation factor eIF2 FEBS Lett. 372 1995 249 252
    • (1995) FEBS Lett. , vol.372 , pp. 249-252
    • Naranda, T.1    Sirangelo, I.2    Fabbri, B.J.3    Hershey, J.W.4
  • 27
    • 71549155597 scopus 로고    scopus 로고
    • Eukaryotic initiator tRNA: Finely tuned and ready for action
    • S.E. Kolitz, and J.R. Lorsch Eukaryotic initiator tRNA: finely tuned and ready for action FEBS Lett. 584 2010 396 404
    • (2010) FEBS Lett. , vol.584 , pp. 396-404
    • Kolitz, S.E.1    Lorsch, J.R.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.