SOD mimetic improves the function, growth, and survival of small-size liver grafts after transplantation in rats

Transplantation

Volumn 94, Issue 7, 2012, Pages 687-694

  Cui, Yi Yao ^a,b   Qian, Jian Min ^c   Yao, Ai Hua ^a   Ma, Zhen Yu ^c   Qian, Xiao Feng ^a   Zha, Xiao Min ^a   Zhao, Yi ^a   Ding, Qiang ^a   Zhao, Jia ^a   Wang, Shui ^a   Wu, Jian ^b  

^a NANJING MEDICAL UNIVERSITY   (China)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c FUDAN UNIVERSITY   (China)

Author keywords

Living donor liver transplantation; Oxidant stress; Small for size syndrome; SOD mimetics

Indexed keywords

ALANINE AMINOTRANSFERASE; ANTIOXIDANT; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; MALONALDEHYDE; MANGANESE TETRAKIS(4 BENZOIC ACID)PORPHYRIN CHLORIDE; MICRORNA; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN C JUN; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; CELL COUNT; CONTROLLED STUDY; DRUG MECHANISM; ENZYME ACTIVITY; GENE; GENE OVEREXPRESSION; GRAFT FAILURE; GRAFT SURVIVAL; INTERLEUKIN 1 BETA GENE; LIVER GRAFT; LIVER NECROSIS; MALE; MOLECULAR PATHOLOGY; NONHUMAN; OXIDATIVE STRESS; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN DNA BINDING; PROTEIN FUNCTION; RAT; REPERFUSION INJURY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEQUENCE ANALYSIS; SMALL FOR SIZE SYNDROME; TUMOR NECROSIS FACTOR ALPHA GENE; UPREGULATION; WESTERN BLOTTING;

ALANINE TRANSAMINASE; ANIMALS; ANTIOXIDANTS; APOPTOSIS; BINDING SITES; BIOLOGICAL MARKERS; DNA; GENE EXPRESSION REGULATION; GRAFT SURVIVAL; INTERLEUKIN-1BETA; LIVER; LIVER REGENERATION; LIVER TRANSPLANTATION; MALE; MALONDIALDEHYDE; METALLOPORPHYRINS; MOLECULAR MIMICRY; NECROSIS; NF-KAPPA B; OXIDATIVE STRESS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; POSTOPERATIVE COMPLICATIONS; PROTO-ONCOGENE PROTEINS C-JUN; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; SUPEROXIDE DISMUTASE; TIME FACTORS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84867240168     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/TP.0b013e3182633478     Document Type: Article

References (25)

1. Florman S, Miller CM. Live donor liver transplantation. Liver Transpl 2006; 12: 499.
2. Fondevila C, Hessheimer AJ, Taura P, et al. Portal hyperperfusion: mechanism of injury and stimulus for regeneration in porcine smallfor-size transplantation. Liver Transpl 2010; 16: 364.
3. Malassagne B, Ferret PJ, Hammoud R, et al. The superoxide dismutase mimetic MnTBAP prevents Fas-induced acute liver failure in the mouse. Gastroenterology 2001; 121: 1451.
4. Salvemini D, Wang ZQ, Zweier JL, et al. A nonpeptidyl mimic of superoxide dismutase with therapeutic activity in rats. Science 1999; 286: 304.
5. Qian JM, Zhang H, Wu XF, et al. Improvement of recipient survival after small size graft liver transplantation in rats with preischemic manipulation or administering antisense against nuclear factor-JB. Transplant Int 2007; 20: 784.
6. Chen X, Murad M, Cui YY, et al. miRNA regulation of liver growth after 50% partial hepatectomy and small size grafts in rats. Transplantation 2011; 91: 293.
7. Laurent A, Nicco C, Tran Van Nhieu J, et al. Pivotal role of superoxide anion and beneficial effect of antioxidant molecules in murine steatohepatitis. Hepatology 2004; 39: 1277.
8. Zhang Y, Venugopal SK, He S, et al. Ethanol induces apoptosis in hepatocytes by a pathway involving novel protein kinase C isoforms. Cellular Signal 2007; 19: 2339.
9. Gonzalez HD, Liu ZW, Cashman S, et al. Small for size syndrome following living donor and split liver transplantation. World J Gastrointest Surg 2010; 2: 389.
10. Ikegami T, Shimada M, Imura S, et al. Current concept of small-for-size grafts in living donor liver transplantation. Surg Today 2008; 38: 971.
11. Botha JF, Langnas AN, Campos BD, et al. Left lobe adult-to-adult living donor liver transplantation: small grafts and hemiportocaval shunts in the prevention of small-for-size syndrome. Liver Transpl 2010; 16: 649.
12. Sainz-Barriga M, Scudeller L, Costa MG, et al. Lack of a correlation between portal vein flow and pressure: toward a shared interpretation of hemodynamic stress governing inflow modulation in liver transplantation. Liver Transplant 2011; 17: 836.
13. Park SJ, Oh EJ, Yoo MA, et al. Involvement of DNA-dependent protein kinase in regulation of stress-induced JNK activation. DNA Cell Biol 2001; 20: 637.
14. Win S, Than TA,HanD, et al. c-JunN-terminal kinase (JNK)Ydependent acute liver injury from acetaminophen or tumor necrosis factor (TNF) requires mitochondrial Sab protein expression in mice. J Biol Chem 2011; 286: 35071.
15. He SQ, Zhang YH, Venugopal SK, et al. Delivery of antioxidative enzyme genes protects against ischemia/reperfusion-induced liver injury in mice. Liver Transpl 2006; 12: 1869.
16. Liu PG, He SQ, Zhang YH, et al. Protective effects of apocynin and allopurinol on ischemia/reperfusion-induced liver injury in mice. World J Gastroenterol 2008; 14: 2832.
17. Perez MJ, Cederbaum AI. Antioxidant and pro-oxidant effects of a manganese porphyrin complex against CYP2E1-dependent toxicity. Free Radic Biol Med 2002; 33: 111.
18. Abou-Seif MA, El-Naggar MM, El-Far M, et al. Amelioration of radiation-induced oxidative stress and biochemical alteration by SOD model compounds in pre-treated F-irradiated rats. Clin Chim Acta 2003; 337: 23.
19. Haga J, Shimazu M, Wakabayashi G, et al. Liver regeneration in donors and adult recipients after living donor liver transplantation. Liver Transpl 2008; 14: 1718.
20. Yao A, Li X, Pu L, et al. Impaired hepatic regeneration by ischemic preconditioning in a rat model of small-for-size liver transplantation. Transplant Immunol 2007; 18: 37.
21. Wu J, Liu L, Yen RD, et al. Liposome-mediated extracellular superoxide dismutase gene delivery protects against acute liver injury in mice. Hepatology 2004; 40: 195.
22. Chen X, Lingala S, Khoobyari S, et al. Epithelial mesenchymal transition and hedgehog signaling activation are associated with chemoresistance and invasion of hepatoma subpopulations. J Hepatol 2011; 55: 838.
23. Wege H, Le HT, Chui MS, et al. Telomerase reconstitution immortalizes human fetal hepatocytes without disrupting their differentiation potential. Gastroenterology 2003; 124: 432.
24. Chen R, Qiu W, Liu Z, et al. Identification of JWA as a novel functional gene responsive to environmental oxidative stress induced by benzo[ a]pyrene and hydrogen peroxide. Free Radic Biol Med 2007; 42: 1704.
25. Liu L, Zern MA, Lizarzaburu ME, et al. Poly(cationic lipid)-mediated in vivo gene delivery to mouse liver. Gene Ther 2003; 10: 180.