Magnetic resonance imaging and volumetric analysis: Novel tools to study the effects of thyroid hormone disruption on white matter development

NeuroToxicology

Volumn 33, Issue 5, 2012, Pages 1322-1329

  Powell, Michael H ^a   Nguyen, Hao Van ^a   Gilbert, Mary ^b   Parekh, Mansi ^c   Colon Perez, Luis M ^d   Mareci, Thomas H ^e   Montie, Eric ^a  

^a UNIVERSITY OF SOUTH CAROLINA BEAUFORT   (United States)

^b U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

^c UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

^d University of Florida   (United States)

^e UNIVERSITY OF FLORIDA   (United States)

Author keywords

Brain; Magnetic resonance imaging; Myelination; Thyroid hormone; White matter

Indexed keywords

LIOTHYRONINE; PROPYLTHIOURACIL; THYROXINE;

ADULT ANIMAL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; BRAIN DEVELOPMENT; BRAIN MALFORMATION; BRAIN SIZE; CONTROLLED STUDY; CORPUS CALLOSUM; EX VIVO STUDY; FEMALE; GRAY MATTER; HIPPOCAMPUS; HYPOTHYROIDISM; IN VIVO STUDY; LIOTHYRONINE BLOOD LEVEL; MALE; NEUROIMAGING; NEUROTOXICITY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PRENATAL DRUG EXPOSURE; PRIORITY JOURNAL; RAT; THYROXINE BLOOD LEVEL; WHITE MATTER;

AGE FACTORS; ANALYSIS OF VARIANCE; ANIMALS; ANIMALS, NEWBORN; ANTITHYROID AGENTS; BODY WEIGHT; BRAIN; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; IMAGING, THREE-DIMENSIONAL; MAGNETIC RESONANCE IMAGING; MALE; NERVE FIBERS, MYELINATED; ORGAN SIZE; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS; PROPYLTHIOURACIL; RATS; RATS, SPRAGUE-DAWLEY; THYROID DISEASES; THYROID HORMONES; TYROSINE 3-MONOOXYGENASE;

ANIMALIA; RATTUS;

EID: 84867233837     PISSN: 0161813X     EISSN: 18729711     Source Type: Journal    
DOI: 10.1016/j.neuro.2012.08.008     Document Type: Article

References (20)

1. Auso E., Lavado-Autric R., Cuevas E., Escobar del Rey F., Morreale de Escobar G., Berbel P. A moderate and transient deficiency of maternal thyroid function at the beginning of fetal neocorticogenesis alters neuronal migration. Endocrinology 2004, 145:4037-4047.
2. Berbel P., Guadano-Ferraz A., Angulo A., Ramon Cerezo J. Role of thyroid hormones in the maturation of interhemispheric connections in rats. Behav Brain Res 1994, 64:9-14.
3. Costa L.G., Giordano G. Developmental neurotoxicity of polybrominated diphenyl ether (PBDE) flame retardants. Neurotoxicology 2007, 28:1047-1067.
4. Gilbert M.E., Sui L. Dose-dependent reductions in spatial learning and synaptic function in the dentate gyrus of adult rats following developmental thyroid hormone insufficiency. Brain Res 2006, 1069:10-22.
5. Gilbert M.E., Zoeller R.T. Thyroid hormones - impact on the developing brain: possible mechanisms of neurotoxicity. Neurotoxicology 2010, Informa Healthcare USA, New York, NY, p. 81-111. 3rd ed.
6. Goodman J.H., Gilbert M.E. Modest thyroid hormone insufficiency during development induces a cellular malformation in the corpus callosum: a model of cortical dysplasia. Endocrinology 2007, 148:2593-2597.
7. Guadano-Ferraz A., Escobar del Rey F., Morreale de Escobar G., Innocenti G., Berbel P. The development of the anterior commissure in normal and hypothyroid rats. Brain Res Dev Brain Res 1994, 81:293-308.
8. Hasegawa M., Kida I., Wada H. A volumetric analysis of the brain and hippocampus of rats rendered perinatal hypothyroid. Neurosci Lett 2010, 479:240-244.
9. Howdeshell K.L. A model of the development of the brain as a construct of the thyroid system. Environ Health Perspect 2002, 110:337-348.
10. Kuriyama S.N., Wanner A., Fidalgo-Neto A.A., Talsness C.E., Koerner W., Chahoud I. Developmental exposure to low-dose PBDE-99: tissue distribution and thyroid hormone levels. Toxicology 2007, 242:80-90.
11. Montie E.W., Pussini N., Schneider G.E., Battey T.W.K., Dennison S., Barakos J., et al. Neuroanatomy and volumes of brain structures of a live California sea lion (Zalophus californianus) from magnetic resonance images. Anat Rec 2009, 292:1523-1547.
12. Montie E.W., Schneider G., Ketten D.R., Marino L., Touhey K.E., Hahn M.E. Volumetric neuroimaging of the Atlantic white-sided dolphin (Lagenorhynchus acutus) brain from in situ magnetic resonance images. Anat Rec 2008, 291:263-282.
13. Morreale de Escobar G., Obregon M.J., Escobar del Rey F. Role of thyroid hormone during early brain development. Eur J Endocrinol 2004, 151:U25-U37.
14. Paul K.B., Hedge J.M., DeVito M.J., Crofton K.M. Developmental triclosan exposure decreases maternal and neonatal thyroxine in rats. Environ Toxicol Chem 2010, 29:2840-2844.
15. Sharlin D.S., Bansal R., Zoeller R.T. Polychlorinated biphenyls exert selective effects on cellular composition of white matter in a manner inconsistent with thyroid hormone insufficiency. Endocrinology 2006, 147:846-858.
16. Sharlin D.S., Tighe D., Gilbert M.E., Zoeller R.T. The balance between oligodendrocyte and astrocyte production in major white matter tracts is linearly related to serum total thyroxine. Endocrinology 2008, 149:2527-2536.
17. Shibutani M., Woo G.-H., Fujimoto H., Saegusa Y., Takahashi M., Inoue K., et al. Assessment of developmental effects of hypothyroidism in rats from in utero and lactation exposure to anti-thyroid agents. Reprod Toxicol 2009, 28:297-307.
18. Wheeler S.M., Willoughby K.A., McAndrews M.P., Rovet J.F. Hippocampal size and memory functioning in children and adolescents with congenital hypothyroidism. J Clin Endocrinol Metab 2011, 9:E1427-E1434.
19. Zoeller R.T., Dowling A.L.S., Herzig C.T.A., Iannacone E.A., Gauger K.J., Bansal R. Thyroid hormone, brain development, and the environment. Environ Health Perspect 2002, 110:355-361.
20. Zoeller R.T., Rovet J. Timing of thyroid hormone action in the developing brain: clinical observations and experimental findings. J Neuroendocrinol 2004, 16:809-818.