Creatine kinase overexpression improves ATP kinetics and contractile function in postischemic myocardium

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 303, Issue 7, 2012, Pages

  Akki, Ashwin ^a   Su, Jason ^a   Yano, Toshiyuki ^a   Gupta, Ashish ^a   Wang, Yibin ^b   Leppo, Michelle K ^a   Chacko, Vadappuram P ^a   Steenbergen, Charles ^a   Weiss, Robert G ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

ATP; Creatine kinase; Ischemia reperfusion; Metabolism

Indexed keywords

ADENOSINE TRIPHOSPHATE; CONTRACTILE PROTEIN; CREATINE KINASE; CREATINE PHOSPHATE; LACTATE DEHYDROGENASE; MUSCLE PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL PH; CONTROLLED STUDY; ENZYME KINETICS; HEART FUNCTION; HEART MUSCLE ISCHEMIA; HEART MUSCLE REPERFUSION; HYPOTHESIS; MALE; MOUSE; NONHUMAN; PHOSPHORUS NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; STATISTICAL SIGNIFICANCE;

ACIDOSIS; ADENOSINE TRIPHOSPHATE; ANIMALS; CREATINE KINASE, MM FORM; DISEASE MODELS, ANIMAL; ENERGY METABOLISM; HYDROGEN-ION CONCENTRATION; KINETICS; L-LACTATE DEHYDROGENASE; MAGNETIC RESONANCE SPECTROSCOPY; MALE; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MYOCARDIAL CONTRACTION; MYOCARDIAL ISCHEMIA; MYOCARDIAL REPERFUSION INJURY; MYOCARDIUM; PHOSPHOCREATINE; UP-REGULATION;

EID: 84867226682     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00268.2012     Document Type: Article

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