Modeling the Zn2+ and Cd2+ metalation mechanism in mammalian metallothionein 1a

Biochemical and Biophysical Research Communications

Volumn 426, Issue 4, 2012, Pages 601-607

  Sutherland, Duncan E K ^a   Summers, Kelly L ^a   Stillman, Martin J ^a  

^a UNIVERSITY OF WESTERN ONTARIO   (Canada)

Author keywords

Cadmium and zinc binding; Cooperative metalation; Human metallothionein; Mechanism of metalation; Metal binding domains; Noncooperative metalation

Indexed keywords

CADMIUM; CYSTEINE; METAL ION; METALLOTHIONEIN I; METALLOTHIONEIN IA; UNCLASSIFIED DRUG; ZINC ION;

ARTICLE; BINDING AFFINITY; DETOXIFICATION; ELECTROSPRAY MASS SPECTROMETRY; HOMEOSTASIS; PRIORITY JOURNAL;

AMINO ACID SEQUENCE; CADMIUM; HUMANS; METALLOTHIONEIN; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; RECOMBINANT PROTEINS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; ZINC;

MAMMALIA;

EID: 84867217283     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2012.08.136     Document Type: Article

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