Arsenic transfer between metallothionein proteins at physiological pH

Biochemical and Biophysical Research Communications

Volumn 401, Issue 1, 2010, Pages 69-74

  Ngu, Thanh T ^a   Dryden, Michael D M ^a   Stillman, Martin J ^a  

^a UNIVERSITY OF WESTERN ONTARIO   (Canada)

Author keywords

Arsenic binding protein; Cysteine; Electrospray ionization mass spectrometry; Metal transfer; Metallothionein; Protein protein interaction

Indexed keywords

APO ALPHA METALLOTHIONEIN; APO BETA METALLOTHIONEIN; ARSENIC; BETA ALPHA METALLOTHIONEIN; CADMIUM; METALLOTHIONEIN; RECOMBINANT METALLOTHIONEIN IA; RECOMBINANT PROTEIN; UNCLASSIFIED DRUG; ZINC;

ARTICLE; BINDING SITE; HUMAN; METALLATION; PH; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN ISOLATION; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; PROTEIN TRANSPORT;

ARSENIC; CADMIUM; ENZYME STABILITY; HUMANS; HYDROGEN-ION CONCENTRATION; ION TRANSPORT; METALLOTHIONEIN; RECOMBINANT PROTEINS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; ZINC;

EID: 77957683417     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2010.09.010     Document Type: Article

References (28)

1. Kagi J.H.R., Nordberg M. Metallothionein 1978, Birkhauser, Boston. First ed.
2. Kagi J.H.R., Kojima Y. Metallothionein II 1985, Birkhauser, Boston. First ed.
3. Stillman M.J., Shaw C.F., Suzuki K.T. Metallothioneins 1992, VCH Publishers, New York. First ed.
4. Suzuki K.T., Imura N., Kimura M. Metallothionein III 1993, Birkhauser, Boston. First ed.
5. Shaw C.F., He L., Munoz A., Savas M.M., Chi S., Fink C.L., Gan T., Petering D.H. Kinetics of reversible N-ethylmaleimide alkylation of metallothionein and the subsequent metal release. J. Biol. Inorg. Chem. 1997, 2:65-73.
6. Pattanaik A., Bachowski G., Laib J., Lemkuil D., Shaw C.F., Petering D.H., Hitchcock A., Saryan L. Properties of the reaction of cis-dichlorodiammineplatinum (II) with metallothionein. J. Biol. Chem. 1992, 267:16121-16128.
7. Krezoski S.K., Villalobos J., Shaw C.F.I., Petering D.H. Kinetic lability of zinc bound to metallothionein in Ehrlich cells. Biochem. J. 1998, 255:483-491.
8. 7-Metallothionein with EDTA. J. Biol. Chem. 1995, 270:5339-5345.
9. Jiang L.-J., Vasak M., Vallee B.L., Maret W. Zinc transfer potential of the α- and β-clusters of metallothionein are affected by domain interactions in the whole molecule. Proc. Natl. Acad. Sci. U.S.A. 2000, 97:2503-2508.
10. Sutherland D.E.K., Willans M.J., Stillman M.J. Supermetalation of the β Domain of Human Metallothionein 1a. Biochemistry 2010, 49:3593-3601.
11. 5 species in the alpha domain of human metallothionein 1a. FEBS J. 2008, 275:2227-2239.
12. 7Metallothionein-3: evidence for an additional zinc binding site. Biochemistry 2009, 48:5700-5707.
13. Ngu T.T., Stillman M.J. Arsenic binding to human metallothionein. J. Am. Chem. Soc. 2006, 128:12473-12483.
14. Ngu T.T., Lee J.A., Rushton M.K., Stillman M.J. Arsenic Metalation of Seaweed Fucus Vesiculosus metallothionein: the importance of the interdomain linker in metallothionein. Biochemistry 2009, 48:8806-8816.
15. Ngu T.T., Lee J.A., Pinter T.B.J., Stillman M.J. Arsenic-metalation of triple-domain human metallothioneins: support for the evolutionary advantage and interdomain metalation of multiple-metal-binding domains. J. Inorg. Biochem. 2010, 104:232-244.
16. Ngu T.T., Easton A., Stillman M.J. Kinetic analysis of Arsenic-Metalation of Human metallothionein: significance of the two-domain structure. J. Am. Chem. Soc. 2008, 130:17016-17028.
17. Ngu T.T., Stillman M.J. Arsenic binding to human metallothionein. J. Am. Chem. Soc. 2006, 128:12473-12483.
18. Merrifield M.E., Huang Z., Kille P., Stillman M.J. Copper speciation in the α and β domains of recombinant human metallothionein by electrospray ionization mass spectrometry. J. Inorg. Biochem. 2002, 88:153-172.
19. Chan J., Huang Z., Merrifield M.E., Salgado M.T., Stillman M.J. Studies of metal binding reactions in metallothionein by spectroscopic, molecular biology, and molecular modeling techniques. Coord. Chem. Rev. 2002, 233-234:319-339.
20. Ngu T.T. M.J. Stillman 2009, Metalation of Metallothionein, IUBMB Life.
21. Ngu T.T., Stillman M.J. Metal-binding mechanism in metallothioneins. Dalton Trans. 2009, 28:5425-5433.
22. Ngu T., Easton A., Stillman M.J. Kinetic analysis of arsenic-metalation of human metallothionein: significance of the two-domain structure. J. Am. Chem. Soc. 2008, 130:17016-17028.
23. Rigby Duncan K.E., Stillman M.J. Metal-dependent protein folding: metallation of metallothionein. J. Inorg. Biochem. 2006, 100:2101-2107.
24. Merrifield M.E., Ngu T., Stillman M.J. Arsenic binding to Fucus vesiculosus metallothionein. Biochem. Biophys. Res. Commun. 2004, 324:127-132.
25. Ngu T.T., Lee J.A., Rushton M.K., Stillman M.J. Arsenic-metalation of seaweed Fucus vesiculosus metallothionein: the importance of the interdomain linker in metallothionein. Biochemistry 2009, 48:8806-8816.
26. Krezel A., Maret W. Thionein/metallothionein control Zn(II) availability and the activity of enzymes. J. Biol. Inorg. Chem. 2008, 13:401-409.
27. Krezel A., Maret W. Dual nanomolar and picomolar zn(ii) binding properties of metallothionein. J. Am. Chem. Soc. 2007, 192:10911-10921.
28. Hase H., Maret W. A differential assay for the reduced and oxidized states of metallothionein and thionein. Anal. Biochem. 2004, 333:19-26.