Urine metabolomics reveals novel physiologic functions of human aldehyde oxidase and provides biomarkers for typing xanthinuria

Metabolomics

Volumn 8, Issue 5, 2012, Pages 951-959

  Peretz, Hava ^a   Watson, David G ^b   Blackburn, Gavin ^b   Zhang, Tong ^b   Lagziel, Ayala ^a   Shtauber Naamati, Meirav ^a   Morad, Tova ^a   Keren Tardai, Elena ^a   Greenshpun, Victoria ^a   Usher, Sali ^a   Shalev, Hanna ^c   Landau, Daniel ^c   Levartovsky, David ^a  

^a TEL AVIV UNIVERSITY   (Israel)

^b UNIVERSITY OF STRATHCLYDE   (United Kingdom)

^c BEN GURION UNIVERSITY OF THE NEGEV   (Israel)

Author keywords

Fourier transform mass spectrometry; Inherited disorders; Molybdo flavo enzymes; Pharmacogenetics; Urine metabolomics

Indexed keywords

(3 ACETAMIDOPROPY)PYRROLIDIN 2 ONE; 1 METHYL 6 OXONICOTINAMIDE; 8 HYDROXYGUANINE; ALDEHYDE DERIVATIVE; ALDEHYDE OXIDASE; AMIDE; BIOLOGICAL MARKER; GENTISALDEHYDE; GENTISIC ACID; GUANINE; HISTIDINE; HYDANTOIN PROPIONIC ACID; HYPOXANTHINE; INOSINE; N1 METHYL 4 PYRIDONE 5 CARBOXAMIDE; PROPIONIC ACID DERIVATIVE; PYRIDOXAL; PYRIDOXIC ACID; PYRROLIDINE DERIVATIVE; SPERMIDINE; UNCLASSIFIED DRUG; URIC ACID; XANTHINE; XANTHINE DEHYDROGENASE; XANTHOSINE;

ADOLESCENT; AGED; AMINO ACID METABOLISM; ARTICLE; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; MALE; MASS SPECTROMETRY; METABOLOMICS; PATHOPHYSIOLOGY; SCHOOL CHILD; URINALYSIS; XANTHINURIA;

EID: 84867205160     PISSN: 15733882     EISSN: 15733890     Source Type: Journal    
DOI: 10.1007/s11306-011-0391-3     Document Type: Article

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