Luminal hypertonicity and acidity modulate colorectal afferents and induce persistent visceral hypersensitivity

American Journal of Physiology - Gastrointestinal and Liver Physiology

Volumn 303, Issue 7, 2012, Pages

  La, Jun Ho ^a   Feng, Bin ^a   Schwartz, Erica S ^a   Brumovsky, Pablo R ^a,b   Gebhart, G F ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b UNIVERSIDAD AUSTRAL   (Argentina)

Author keywords

Carbohydrate malabsorption; Colorectal distension; Intraluminal acidity; Intraluminal hypertonicity

Indexed keywords

HYPERTONIC SOLUTION; MITOGEN ACTIVATED PROTEIN KINASE;

ABDOMINAL PAIN; ACIDITY; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BEHAVIOR; COLON DILATATION; COLORECTAL AFFERENT; CONTROLLED STUDY; HYPERSENSITIVITY; IN VITRO STUDY; MALE; MOUSE; MUSCLE SPINDLE AFFERENT NERVE; MUSCLE STRETCHING; NERVE CELL; NERVE EXCITABILITY; NOCICEPTION; NONHUMAN; OSMOLARITY; PELVIC NERVE; PH; PRIORITY JOURNAL; PROTEIN EXPRESSION; SENSORY NERVE; SENSORY NERVE CONDUCTION; SEROSA;

ADMINISTRATION, RECTAL; ANIMALS; BEHAVIOR, ANIMAL; COLON; DILATATION; HYPERSENSITIVITY; LACTOSE INTOLERANCE; MECHANORECEPTORS; MECHANOTRANSDUCTION, CELLULAR; MICE; MICE, INBRED C57BL; PHYSICAL STIMULATION; RECTUM; SALINE SOLUTION, HYPERTONIC; VISCERAL AFFERENTS;

EID: 84867172254     PISSN: 01931857     EISSN: 15221547     Source Type: Journal    
DOI: 10.1152/ajpgi.00259.2012     Document Type: Article

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