Pre-Diabetes Augments Neuropeptide Y1- and α1-Receptor Control of Basal Hindlimb Vascular Tone in Young ZDF Rats

PLoS ONE

Volumn 7, Issue 10, 2012, Pages

  Novielli, Nicole M ^a   Al Khazraji, Baraa K ^a   Medeiros, Philip J ^a   Goldman, Daniel ^a   Jackson, Dwayne N ^a  

^a UNIVERSITY OF WESTERN ONTARIO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

NALPHA (DIPHENYLACETYL) N (4 HYDROXYBENZYL) DEXTRO ARGININAMIDE; NEUROPEPTIDE ALPHA1 RECEPTOR; NEUROPEPTIDE RECEPTOR; NEUROPEPTIDE Y1 RECEPTOR; PRAZOSIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD VESSEL TONE; CONTROLLED STUDY; HINDLIMB; IMPAIRED GLUCOSE TOLERANCE; LEG BLOOD FLOW; MALE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; RAT; SKELETAL MUSCLE; SYMPATHETIC BLOCKING; SYMPATHETIC FUNCTION;

ACETYLCHOLINE; ADRENERGIC ALPHA-1 RECEPTOR AGONISTS; ADRENERGIC ALPHA-1 RECEPTOR ANTAGONISTS; ANIMALS; ARGININE; BLOOD PRESSURE; DRUG SYNERGISM; HEART RATE; HINDLIMB; MALE; MUSCLE, SKELETAL; NEUROPEPTIDE Y; NITRIC OXIDE DONORS; NITROPRUSSIDE; PRAZOSIN; PREDIABETIC STATE; RATS; RECEPTORS, ADRENERGIC, ALPHA-1; RECEPTORS, NEUROPEPTIDE Y; REGIONAL BLOOD FLOW; VASOCONSTRICTION;

RATTUS;

EID: 84867164067     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0046659     Document Type: Article

References (46)

1. Zukowska-Grojec Z, (1995) Neuropeptide Y. A novel sympathetic stress hormone and more. Ann N Y Acad Sci 771: 219-233.
2. Malmstrom RE, (1997) Neuropeptide Y Y1 receptor mechanisms in sympathetic vascular control. Acta Physiol Scand Suppl 636: 1-55.
3. Ekelund U, Erlinge D, (1997) In vivo receptor characterization of neuropeptide Y-induced effects in consecutive vascular sections of cat skeletal muscle. Br J Pharmacol 120: 387-392.
4. Zukowska-Grojec Z, Wahlestedt C (1993) Origin and actions of neuropeptide Y in the cardiovascular system. The Biology of Neuropeptide Y and Related Peptide, ed Colmers WF & Wahlestedt. Totowa: Humana Press. pp.315-388.
5. Jackson DN, Noble EG, Shoemaker JK, (2004) Y1- and alpha1-receptor control of basal hindlimb vascular tone. Am J Physiol Regul Integr Comp Physiol 287: R228-233.
6. Bartfai T, Iverfeldt K, Fisone G, Serfozo P, (1988) Regulation of the release of coexisting neurotransmitters. Annu Rev Pharmacol Toxicol 28: 285-310.
7. De Camilli P, Jahn R, (1990) Pathways to regulated exocytosis in neurons. Annu Rev Physiol 52: 625-645.
8. Lundberg JM, Franco-Cereceda A, Lou YP, Modin A, Pernow J, (1994) Differential release of classical transmitters and peptides. Adv Second Messenger Phosphoprotein Res 29: 223-234.
9. Faeh D, William J, Yerly P, Paccaud F, Bovet P, (2007) Diabetes and pre-diabetes are associated with cardiovascular risk factors and carotid/femoral intima-media thickness independently of markers of insulin resistance and adiposity. Cardiovasc Diabetol 6: 32.
10. Haffner SM, Stern MP, Hazuda HP, Mitchell BD, Patterson JK, (1990) Cardiovascular risk factors in confirmed prediabetic individuals. Does the clock for coronary heart disease start ticking before the onset of clinical diabetes? JAMA 263: 2893-2898.
11. Mancia G, Grassi G, Giannattasio C, Seravalle G, (1999) Sympathetic activation in the pathogenesis of hypertension and progression of organ damage. Hypertension 34: 724-728.
12. Huggett RJ, Hogarth AJ, Mackintosh AF, Mary DA, (2006) Sympathetic nerve hyperactivity in non-diabetic offspring of patients with type 2 diabetes mellitus. Diabetologia 49: 2741-2744.
13. Anderson EA, Balon TW, Hoffman RP, Sinkey CA, Mark AL, (1992) Insulin increases sympathetic activity but not blood pressure in borderline hypertensive humans. Hypertension 19: 621-627.
14. DeFronzo RA, Ferrannini E, (1991) Insulin resistance. A multifaceted syndrome responsible for NIDDM, obesity, hypertension, dyslipidemia, and atherosclerotic cardiovascular disease. Diabetes Care 14: 173-194.
15. Esler M, Rumantir M, Wiesner G, Kaye D, Hastings J, et al. (2001) Sympathetic nervous system and insulin resistance: from obesity to diabetes. Am J Hypertens 14: 304S-309S.
16. Scherrer U, Sartori C, (1997) Insulin as a vascular and sympathoexcitatory hormone: implications for blood pressure regulation, insulin sensitivity, and cardiovascular morbidity. Circulation 96: 4104-4113.
17. Muntzel MS, Anderson EA, Johnson AK, Mark AL, (1995) Mechanisms of insulin action on sympathetic nerve activity. Clin Exp Hypertens 17: 39-50.
18. Epstein M, Sowers JR, (1992) Diabetes mellitus and hypertension. Hypertension 19: 403-418.
19. Okon EB, Szado T, Laher I, McManus B, van Breemen C, (2003) Augmented contractile response of vascular smooth muscle in a diabetic mouse model. J Vasc Res 40: 520-530.
20. Lesniewski LA, Donato AJ, Behnke BJ, Woodman CR, Laughlin MH, et al. (2008) Decreased NO signaling leads to enhanced vasoconstrictor responsiveness in skeletal muscle arterioles of the ZDF rat prior to overt diabetes and hypertension. Am J Physiol Heart Circ Physiol 294: H1840-1850.
21. Leonard BL, Watson RN, Loomes KM, Phillips AR, Cooper GJ, (2005) Insulin resistance in the Zucker diabetic fatty rat: a metabolic characterisation of obese and lean phenotypes. Acta Diabetol 42: 162-170.
22. Kim SH, Reaven GM, (2008) Insulin resistance and hyperinsulinemia: you can't have one without the other. Diabetes Care 31: 1433-1438.
23. Kim SH, Reaven GM, (2008) Isolated impaired fasting glucose and peripheral insulin sensitivity: not a simple relationship. Diabetes Care 31: 347-352.
24. Soma LR, (1983) Anesthetic and analgesic considerations in the experimental animal. Ann N Y Acad Sci 406: 32-47.
25. Jackson DN, Milne KJ, Noble EG, Shoemaker JK, (2005) Neuropeptide Y bioavailability is suppressed in the hindlimb of female Sprague-Dawley rats. J Physiol 568: 573-581.
26. Jackson DN, Ellis CG, Shoemaker JK, (2010) Estrogen modulates the contribution of neuropeptide Y to baseline hindlimb blood flow control in female Sprague Dawley rats. Am J Physiol Regul Integr Comp Physiol.
27. Jackson DN, Milne KJ, Noble EG, Shoemaker JK, (2005) Gender-modulated endogenous baseline neuropeptide Y Y1-receptor activation in the hindlimb of Sprague-Dawley rats. J Physiol 562: 285-294.
28. Terjung RL, Engbretson BM, (1988) Blood flow to different rat skeletal muscle fiber type sections during isometric contractions in situ. Med Sci Sports Exerc 20: S124-130.
29. Armstrong RB, Laughlin MH, (1984) Exercise blood flow patterns within and among rat muscles after training. Am J Physiol 246: H59-68.
30. Laughlin MH, Armstrong RB, (1983) Rat muscle blood flows as a function of time during prolonged slow treadmill exercise. Am J Physiol 244: H814-824.
31. Armstrong RB, Phelps RO, (1984) Muscle fiber type composition of the rat hindlimb. Am J Anat 171: 259-272.
32. Bradford MM, (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72: 248-254.
33. Ellis CG, Goldman D, Hanson M, Stephenson AH, Milkovich S, et al. (2010) Defects in oxygen supply to skeletal muscle of prediabetic ZDF rats. Am J Physiol Heart Circ Physiol 298: H1661-1670.
34. Frisbee JC, (2004) Enhanced arteriolar alpha-adrenergic constriction impairs dilator responses and skeletal muscle perfusion in obese Zucker rats. J Appl Physiol 97: 764-772.
35. Chen YL, Wolin MS, Messina EJ, (1996) Evidence for cGMP mediation of skeletal muscle arteriolar dilation to lactate. J Appl Physiol 81: 349-354.
36. Lovejoy J, Newby FD, Gebhart SS, DiGirolamo M, (1992) Insulin resistance in obesity is associated with elevated basal lactate levels and diminished lactate appearance following intravenous glucose and insulin. Metabolism 41: 22-27.
37. Crawford SO, Hoogeveen RC, Brancati FL, Astor BC, Ballantyne CM, et al. (2010) Association of blood lactate with type 2 diabetes: the Atherosclerosis Risk in Communities Carotid MRI Study. Int J Epidemiol.
38. Lundberg JM, (1996) Pharmacology of cotransmission in the autonomic nervous system: integrative aspects on amines, neuropeptides, adenosine triphosphate, amino acids and nitric oxide. Pharmacol Rev 48: 113-178.
39. Eisenhofer G, Goldstein DS, Kopin IJ, (1989) Plasma dihydroxyphenylglycol for estimation of noradrenaline neuronal re-uptake in the sympathetic nervous system in vivo. Clin Sci (Lond) 76: 171-182.
40. Huggett RJ, Scott EM, Gilbey SG, Stoker JB, Mackintosh AF, et al. (2003) Impact of type 2 diabetes mellitus on sympathetic neural mechanisms in hypertension. Circulation 108: 3097-3101.
41. Matyal R, Mahmood F, Robich M, Glazer H, Khabbaz K, et al. (2011) Chronic type II diabetes mellitus leads to changes in neuropeptide Y receptor expression and distribution in human myocardial tissue. Eur J Pharmacol 665: 19-28.
42. Chottova Dvorakova M, Wiegand S, Pesta M, Slavikova J, Grau V, et al. (2008) Expression of neuropeptide Y and its receptors Y1 and Y2 in the rat heart and its supplying autonomic and spinal sensory ganglia in experimentally induced diabetes. Neuroscience 151: 1016-1028.
43. Hu ZW, Shi XY, Hoffman BB, (1996) Insulin and insulin-like growth factor I differentially induce alpha1-adrenergic receptor subtype expression in rat vascular smooth muscle cells. J Clin Invest 98: 1826-1834.
44. Franco-Cereceda A, Liska J, (1998) Neuropeptide Y Y1 receptors in vascular pharmacology. Eur J Pharmacol 349: 1-14.
45. Martin WH 3rd, Tolley TK, Saffitz JE, (1990) Autoradiographic delineation of skeletal muscle alpha 1-adrenergic receptor distribution. Am J Physiol 259: H1402-1408.
46. Zukowska-Grojec Z, Konarska M, McCarty R, (1988) Differential plasma catecholamine and neuropeptide Y responses to acute stress in rats. Life Sci 42: 1615-1624.