Regulation of cofilin activity by CaMKII and calcineurin

American Journal of the Medical Sciences

Volumn 344, Issue 6, 2012, Pages 462-472

  Zhao, Jian Wu ^a,b   Gao, Zhong Li ^c   Ji, Qiu Ye ^c   Wang, Hong ^c   Zhang, Han Yang ^c   Yang, Yu Dan ^c   Xing, Feng Juan ^c   Meng, Ling Jie ^c   Wang, Yan ^b  

^a CHINA JAPAN UNION HOSPITAL OF JILIN UNIVERSITY   (China)

^b JILIN UNIVERSITY   (China)

^c NONE

Author keywords

Calcineurin (Cn); Calcium calmodulin dependent protein kinase II (CaMKII); Cofilin activity

Indexed keywords

CALCINEURIN; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE II; CALCIUM ION; COFILIN; LIM KINASE 1; PROTEIN; PROTEIN PHOSPHATASE SLINGSHOT 1L; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; HUMAN; HUMAN CELL; NONHUMAN; PROTEIN DEPHOSPHORYLATION; PROTEIN PHOSPHORYLATION;

EID: 84867150041     PISSN: 00029629     EISSN: 15382990     Source Type: Journal    
DOI: 10.1097/MAJ.0b013e318244745b     Document Type: Article

References (25)

1. Wang Y, Shibasaki F, Mizuno K. Calcium signal-induced cofilin dephosphorylation is mediated by Slingshot via calcineurin. J Biol Chem 2005;280: 12683-9.
2. Nishita M, Wang Y, Tomizawa C, et al. Phosphoinositide 3-kinasemediated activation of cofilin phosphatase Slingshot and its role for insulin-induced membrane protrusion. J Biol Chem 2004;279: 7193-8.
3. Moon A, Drubin DG. The ADF/cofilin proteins: stimulus-responsive modulators of actin dynamics. Mol Biol Cell 1995;6: 1423-31.
4. Gohla A, Birkenfeld J, Bokoch GM. Chronophin, a novel HAD-type serine protein phosphatase, regulates cofilin-dependent actin dynamics. Nat Cell Biol 2005;7: 21-9.
5. Hall A. Rho GTPases and the actin cytoskeleton. Science 1998;279: 509-14.
6. Nagata-Ohashi K, Ohta Y, Goto K, et al. A pathway of neuregulininduced activation of cofilin-phosphatase Slingshot and cofilin in lamellipodia. J Cell Biol 2004;165: 465-71.
7. Wayman GA, Lee YS, Tokumitsu H, et al. Calmodulin-kinases: modulators of neuronal development and plasticity. Neuron 2008;59: 914-31.
8. Takemura M, Mishima T, Wang Y, et al. Ca2+/calmodulin-dependent protein kinase IV-mediated LIM kinase activation is critical for calcium signal-induced neurite outgrowth. J Biol Chem 2009;284: 28554-62.
9. Okano I, Hiraoka J, Otera H, et al. Identification and characterization of a novel family of serine/threonine kinases containing two N-terminal LIM motifs. J Biol Chem 1995;270: 31321-30.
10. Kaji N, Ohashi K, Shuin M, et al. Cell cycle-associated changes in Slingshot phosphatase activity and roles in cytokinesis in animal cells. J Biol Chem 2003;278: 33450-5.
11. Klee CB, Ren H, Wang X. Regulation of the calmodulin-stimulated protein phosphatase, calcineurin. J Biol Chem 1998;273: 13367-70.
12. Shibasaki F, Price ER, Milan D, et al. Role of kinases and the phosphatase calcineurin in the nuclear shuttling of transcription factor NF-AT4. Nature 1996;382: 370-3.
13. Soosairajah J, Maiti S, O'Neil Wiggan P, et al. Interplay between components of a novel LIM kinase-slingshot phosphatase complex regulates cofilin. EMBO J 2005;24: 473-86.
14. Niwa R, Nagata-Ohashi K, Takeichi M, et al. Control of actin reorganization by Slingshot, a family of phosphatases that dephosphorylate ADF/cofilin. Cell 2002;108: 233-46.
15. Yamamoto M, Nagata-Ohashi K, Ohta Y, et al. Identification of multiple actin-binding sites in cofilin-phosphatase Slingshot-1L. FEBS Lett 2006;580: 1789-94.
16. Brummelkamp TR, Bernards R, Agami R. A system for stable expression of short interfering RNAs in mammalian cells. Science 2002;296: 550-3.
17. Rochlitz H, Voigt A, Lankat-Buttgereit B, et al. Cloning and quantitative determination of the human Ca2+/calmodulin-dependent protein kinase II (CaMK II) isoforms in human beta cells. Diabetologia 2000; 43: 465-73.
18. Ohashi K, Nagata K, Maekawa M, et al. Rho-associated kinase ROCK activates LIM-kinase 1 by phosphorylation at threonine 508 within the activation loop. J Biol Chem 2000;275: 3577-82.
19. Molkentin JD, Lu JR, Antos CL, et al. A calcineurin-dependent transcriptional pathway for cardiac hypertrophy. Cell 1998;93: 215-28.
20. Molkentin JD. Calcineurin and beyond: cardiac hypertrophic signaling. Circ Res 2000;87: 731-8.
21. Wilkins BJ, Molkentin JD. Calcium-calcineurin signaling in the regulation of cardiac hypertrophy. Biochem Biophys Res Commun 2004; 322: 1178-91.
22. Aifantis I, Gounari F, Scorrano L, et al. Constitutive pre-TCR signaling promotes differentiation through Ca2+ mobilization and activation of NF-kB and NFAT. Nature Immunol 2001;2: 403-9.
23. Zhang XW, Kong WJ. Effects of A23187 on intracellular free Ca2+ concentration and apoptosis on human squamous cell carcinoma of larynx. Lin Chuang Er Bi Yan Hou Ke Za Zhi 2005;11: 507-9.
24. Csaba M, Janos F, Zsolt S, et al. Cytosolic free Ca2+ concentration exhibits a characteristic temporal pattern during in vitro cartilage differentiation: a possible regulatory role of calcineurin in Ca-signalling of chondrogenic cells. Cell Calcium 2008;44: 310-23.
25. Cheeti S, Lee CH. The involvement of intracellular calcium in the MCT-mediated uptake of lactic acid by HeLa cells. Mol Pharm 2010; 7: 169-76.