메뉴 건너뛰기




Volumn 72, Issue 19, 2012, Pages 4954-4962

Frequent PVT1 rearrangement and novel chimeric genes PVT1-NBEA and PVT1-WWOX occur in multiple myeloma with 8q24 abnormality

Author keywords

[No Author keywords available]

Indexed keywords

MYC PROTEIN;

EID: 84867134177     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-12-0213     Document Type: Article
Times cited : (87)

References (50)
  • 1
    • 74049162897 scopus 로고    scopus 로고
    • International Myeloma Working Group molecular classification of multiple myeloma: Spotlight review
    • International Myeloma Working Group
    • Fonseca R, Bergsagel PL, Drach J, Shaughnessy J, Gutierrez N, Stewart AK, et al. International Myeloma Working Group. International Myeloma Working Group molecular classification of multiple myeloma: spotlight review. Leukemia 2009;23:2210-21.
    • (2009) Leukemia , vol.23 , pp. 2210-2221
    • Fonseca, R.1    Bergsagel, P.L.2    Drach, J.3    Shaughnessy, J.4    Gutierrez, N.5    Stewart, A.K.6
  • 6
    • 0030792866 scopus 로고    scopus 로고
    • The Ig heavy chain gene is frequently involved in chromosomal translocations in multiple myeloma and plasma cell leukemia as detected by in situ hybridization
    • Nishida K, Tamura A, Nakazawa N, Ueda Y, Abe T, Matsuda F, et al. The Ig heavy chain gene is frequently involved in chromosomal translocations in multiple myeloma and plasma cell leukemia as detected by in situ hybridization. Blood 1997;90:526-34. (Pubitemid 27299091)
    • (1997) Blood , vol.90 , Issue.2 , pp. 526-534
    • Nishida, K.1    Tamura, A.2    Nakazawa, N.3    Ueda, Y.4    Abe, T.5    Matsuda, F.6    Kashima, K.7    Taniwaki, M.8
  • 7
    • 0035892119 scopus 로고    scopus 로고
    • Rearrangementsof the c-myc oncogene are present in 15% of primary human multiple myeloma tumors
    • Intergroupe Francophone du Myélome
    • Avet-Loiseau H, Gerson F, Magrangeas F, Minvielle S, Harousseau JL, Bataille R, et al. Intergroupe Francophone du Myélome. Rearrangementsof the c-myc oncogene are present in 15% of primary human multiple myeloma tumors. Blood 2001;98:3082-6.
    • (2001) Blood , vol.98 , pp. 3082-3086
    • Avet-Loiseau, H.1    Gerson, F.2    Magrangeas, F.3    Minvielle, S.4    Harousseau, J.L.5    Bataille, R.6
  • 12
    • 0035253869 scopus 로고    scopus 로고
    • Cytogenetic, interphase, and multicolor fluorescence in situ hybridization analyses in primary plasma cell leukemia: A study of 40 patients at diagnosis, on behalf of the Intergroupe Francophone du Myélome and the Groupe Français de Cytogénétique Hématologique
    • DOI 10.1182/blood.V97.3.822
    • Avet-Loiseau H, Daviet A, Brigaudeau C, Callet-Bauchu E, TerréC, Lafage-Pochitaloff M, et al. Cytogenetic, interphase, and multicolor fluorescence in situ hybridization analyses in primary plasma cell leukemia: a study of 40 patients at diagnosis, on behalf of the Intergroupe Francophone du Myélome and theGroupe Français de Cytogénétique Hématologique. Blood 2001;97:822-5. (Pubitemid 32113422)
    • (2001) Blood , vol.97 , Issue.3 , pp. 822-825
    • Avet-Loiseau, H.1    Daviet, A.2    Brigaudeau, C.3    Callet-Bauchu, E.4    Terre, C.5    Lafage-Pochitaloff, M.6    Desangles, F.7    Ramond, S.8    Talmant, P.9    Bataille, R.10
  • 13
    • 36749014487 scopus 로고    scopus 로고
    • Chromosome aberrations in a series of 120 multiple myeloma cases with abnormal karyotypes
    • DOI 10.1002/ajh.20998
    • Mohamed AN, Bentley G, Bonnett ML, Zonder J, Al-Katib A. Chromosome aberrations in a series of 120 multiple myeloma cases with abnormal karyotypes. Am J Hematol 2007;82:1080-7. (Pubitemid 350209850)
    • (2007) American Journal of Hematology , vol.82 , Issue.12 , pp. 1080-1087
    • Mohamed, A.N.1    Bentley, G.2    Bonnett, M.L.3    Zonder, J.4    Al-Katib, A.5
  • 14
    • 0025272679 scopus 로고
    • Localization of breakpoints by polymerase chain reactions in Burkitt's lymphoma with 8;14 translocations
    • Shiramizu B, Magrath I. Localization of breakpoints by polymerase chain reactions in Burkitt's lymphoma with 8;14 translocations. Blood 1990;75:1848-52. (Pubitemid 20161500)
    • (1990) Blood , vol.75 , Issue.9 , pp. 1848-1852
    • Shiramizu, B.1    Magrath, I.2
  • 15
    • 0025212309 scopus 로고
    • Effects of translocations on transcription from PVT
    • Shtivelman E, Bishop JM. Effects of translocations on transcription from PVT. Mol Cell Biol 1990;10:1835-9.
    • (1990) Mol Cell Biol , vol.10 , pp. 1835-1839
    • Shtivelman, E.1    Bishop, J.M.2
  • 16
    • 84872618214 scopus 로고    scopus 로고
    • Establishment and characterization of a novel human myeloma cell line, AMU-MM1, from a multiple myeloma patient involving central nerve system after treatment with bortezomib
    • abstract [4991]
    • Hanamura I, Goto M, Nagoshi H, Taki T, Imai N, Suganuma K, et al. Establishment and characterization of a novel human myeloma cell line, AMU-MM1, from a multiple myeloma patient involving central nerve system after treatment with bortezomib. Blood 2010;116: (abstract [4991]).
    • (2010) Blood , vol.116
    • Hanamura, I.1    Goto, M.2    Nagoshi, H.3    Taki, T.4    Imai, N.5    Suganuma, K.6
  • 17
    • 0029093754 scopus 로고
    • Translocations and amplification of the BCL2 gene are detected in interphase nuclei of non-Hodgkin's lymphoma by in situ hybridization with yeast artificial chromosome clones
    • Taniwaki M, Sliverman GA, Nishida K, Horiike S, Misawa S, Shimazaki C, et al. Translocations and amplification of the BCL2 gene are detected in interphase nuclei of non-Hodgkin's lymphoma by in situ hybridization with yeast artificial chromosome clones. Blood 1995;86:1481-6.
    • (1995) Blood , vol.86 , pp. 1481-1486
    • Taniwaki, M.1    Sliverman, G.A.2    Nishida, K.3    Horiike, S.4    Misawa, S.5    Shimazaki, C.6
  • 21
    • 41649109612 scopus 로고    scopus 로고
    • Identification of the novel AML1 fusion partner gene, LAF4, a fusion partner of MLL, in childhood T-cell acute lymphoblastic leukemia with t(2;21)(q11;q22) by bubble PCR method for cDNA
    • DOI 10.1038/sj.onc.1210857, PII 1210857
    • Chinen Y, Taki T, Nishida K, Shimizu D, Okuda T, Yoshida N, et al. Identification of the novel AML1 fusion partner gene, LAF4, a fusion partner of MLL, in childhood T-cell acute lymphoblastic leukemia with t (2;21)(q11;q22) by bubble PCR method for cDNA. Oncogene 2008;27: 2249-56. (Pubitemid 351483379)
    • (2008) Oncogene , vol.27 , Issue.15 , pp. 2249-2256
    • Chinen, Y.1    Taki, T.2    Nishida, K.3    Shimizu, D.4    Okuda, T.5    Yoshida, N.6    Kobayashi, C.7    Koike, K.8    Tsuchida, M.9    Hayashi, Y.10    Taniwaki, M.11
  • 22
    • 0024596932 scopus 로고
    • Three breakpoints of variant t(2;8) translocations in Burkitt's lymphoma cells fall within a region 140 kilobases distal from c-myc
    • Henglein B, Synovzik H, Groitl P, Bornkamm GW, Hartl P, Lipp M. Three breakpoints of variant t(2;8) translocations in Burkitt's lymphoma cells fall within a region 140 kilobases distal from c-myc. Mol Cell Biol 1989;9:2105-13. (Pubitemid 19117811)
    • (1989) Molecular and Cellular Biology , vol.9 , Issue.5 , pp. 2105-2113
    • Henglein, B.1    Synovzik, H.2    Groitl, P.3    Bornkamm, G.W.4    Hartl, P.5    Lipp, M.6
  • 23
    • 0031691652 scopus 로고    scopus 로고
    • Simultaneous detection of MYC, BVR1, and PVT1 translocations in lymphoid malignancies by fluorescence in situ hybridization
    • DOI 10.1002/(SICI)1098-2264(199811)23:3<220::AID-GCC3>3.0.CO;2-3
    • Rack KA, Delabesse E, Radford-Weiss I, Bourquelot P, Le Guyader G, Vekemans M, et al. Simultaneous detection of MYC, BVR1, and PVT1 translocations in lymphoid malignancies by fluorescence in situ hybridization. Genes Chromosomes Cancer 1998;23:220-6. (Pubitemid 28465638)
    • (1998) Genes Chromosomes and Cancer , vol.23 , Issue.3 , pp. 220-226
    • Rack, K.A.1    Delabesse, E.2    Radford-Weiss, I.3    Bourquelot, P.4    Le, G.G.5    Vekemans, M.6    Macintyre, E.A.7
  • 24
    • 0022590151 scopus 로고
    • Proviral integration site Mis-1 in rat thymomas corresponds to the pvt-1 translocation breakpoint in murine plasmacytomas
    • Villeneuve L, Rassart E, Jolicoeur P, Graham M, Adams JM. Proviral integration site Mis-1 in rat thymomas corresponds to the pvt-1 translocation breakpoint in murine plasmacytomas. Mol Cell Biol 1986;6:1834-7. (Pubitemid 16121276)
    • (1986) Molecular and Cellular Biology , vol.6 , Issue.5 , pp. 1834-1837
    • Villeneuve, L.1    Rassart, E.2    Jolicoeur, P.3
  • 25
    • 0028582155 scopus 로고
    • Chimeric transcripts with an open reading frame are generated as a result of translocation to the Pvt-1 region in mouse B-cell tumors
    • Huppi K, Siwarski D. Chimeric transcripts with an open reading frame are generated as a result of translocation to the Pvt-1 region in mouse B-cell tumors. Int J Cancer 1994;59:848-51.
    • (1994) Int J Cancer , vol.59 , pp. 848-851
    • Huppi, K.1    Siwarski, D.2
  • 26
    • 0023790354 scopus 로고
    • Amplification of c-myc and pvt-1 homologous sequences in acute nonlymphatic leukemia
    • Asker C, Mareni C, Coviello D, Ingvarsson S, Sessarego M, Origone P, et al. Amplification of c-myc and pvt-1 homologous sequences in acute nonlymphatic leukemia. Leuk Res 1988;12:523-7.
    • (1988) Leuk Res , vol.12 , pp. 523-527
    • Asker, C.1    Mareni, C.2    Coviello, D.3    Ingvarsson, S.4    Sessarego, M.5    Origone, P.6
  • 27
    • 0024536201 scopus 로고
    • The PVT gene frequently amplifies with MYC in tumor cells
    • Shtivelman E, Bishop JM. The PVT gene frequently amplifies with MYC in tumor cells. Mol Cell Biol 1989;9:1148-54. (Pubitemid 19071683)
    • (1989) Molecular and Cellular Biology , vol.9 , Issue.3 , pp. 1148-1154
    • Shtivelman, E.1    Bishop, J.M.2
  • 29
    • 33646471662 scopus 로고    scopus 로고
    • Pre-B cell proliferation and lymphoblastic leukemia/high-grade lymphoma in E(mu)-miR155 transgenic mice
    • Costinean S, Zanesi N, Pekarsky Y, Tili E, Volinia S, Heerema N, et al. Pre-B cell proliferation and lymphoblastic leukemia/high-grade lymphoma in E(mu)-miR155 transgenic mice. Proc Natl Acad Sci U S A 2006;103:7024-9.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 7024-7029
    • Costinean, S.1    Zanesi, N.2    Pekarsky, Y.3    Tili, E.4    Volinia, S.5    Heerema, N.6
  • 33
    • 0025195918 scopus 로고
    • Human homologoue of molony leukemia virus integration-4 locus (MLVI-4), located 20 kilobases 3' of the myc gene, is rearranged in multiple myelomas
    • Palumbo AP, Boccadoro M, Battaglio S, Corradini P, Tsichlis PN, Huebner K, et al. Human homologue of Moloney leukemia virus integration-4 locus (MLVI-4), located 20 kilobases 3′ of the myc gene, is rearranged in multiple myelomas. Cancer Res 1990;50:6478-82. (Pubitemid 20348763)
    • (1990) Cancer Research , vol.50 , Issue.20 , pp. 6478-6482
    • Palumbo, A.P.1    Boccadoro, M.2    Battaglio, S.3    Corradini, P.4    Tsichlis, P.N.5    Huebner, K.6    Pileri, A.7    Croce, C.M.8
  • 34
    • 0034548872 scopus 로고    scopus 로고
    • Neurobeachin: A protein kinase A-anchoring, beige/Chediakhigashi protein homolog implicated in neuronal membrane traffic
    • Wang X, Herberg FW, Laue MM, Wullner C, Hu B, Petrasch-Parwez E, et al. Neurobeachin: a protein kinase A-anchoring, beige/Chediakhigashi protein homolog implicated in neuronal membrane traffic. J Neurosci 2000;20:8551-65.
    • (2000) J Neurosci , vol.20 , pp. 8551-8565
    • Wang, X.1    Herberg, F.W.2    Laue, M.M.3    Wullner, C.4    Hu, B.5    Petrasch-Parwez, E.6
  • 36
    • 58149195202 scopus 로고    scopus 로고
    • Neurobeachin (NBEA) is a target of recurrent interstitial deletions at 13q13 in patients with MGUS and multiple myeloma
    • O'Neal J, Gao F, Hassan A, Monahan R, Barrios S, Kilimann MW, et al. Neurobeachin (NBEA) is a target of recurrent interstitial deletions at 13q13 in patients with MGUS and multiple myeloma. Exp Hematol 2009;37:234-44.
    • (2009) Exp Hematol , vol.37 , pp. 234-244
    • O'Neal, J.1    Gao, F.2    Hassan, A.3    Monahan, R.4    Barrios, S.5    Kilimann, M.W.6
  • 37
    • 33748638843 scopus 로고    scopus 로고
    • Identification of recurrent chromosomal breakpoints in multiple myeloma with complex karyotypes by combined G-banding, spectral karyotyping, and fluorescence in situ hybridization analyses
    • DOI 10.1016/j.cancergencyto.2006.04.008, PII S0165460806002585
    • Sáez B, Martín-Subero JI, Largo C, Martín MC, Odero MD, Prosper F,et al. Identification of recurrent chromosomal breakpoints in multiple myeloma with complex karyotypes by combined G-banding, spectral karyotyping, and fluorescence in situ hybridization analyses. Cancer Genet Cytogenet 2006;169:143-9. (Pubitemid 44382606)
    • (2006) Cancer Genetics and Cytogenetics , vol.169 , Issue.2 , pp. 143-149
    • Saez, B.1    Martin-Subero, J.I.2    Largo, C.3    Martin, M.C.4    Odero, M.D.5    Prosper, F.6    Siebert, R.7    Calasanz, M.J.8    Cigudosa, J.C.9
  • 38
    • 67650745974 scopus 로고    scopus 로고
    • UK Myeloma Forum. Loss of 1p and rearrangement of MYC are associated with progression of smouldering myeloma to myeloma: Sequential analysis of a single case
    • Chiecchio L, Dagrada GP, Protheroe RK, Stockley DM, Smith AG, Orchard KH, et al. UK Myeloma Forum. Loss of 1p and rearrangement of MYC are associated with progression of smouldering myeloma to myeloma: sequential analysis of a single case. Haematologica 2009;94:1024-8.
    • (2009) Haematologica , vol.94 , pp. 1024-1028
    • Chiecchio, L.1    Dagrada, G.P.2    Protheroe, R.K.3    Stockley, D.M.4    Smith, A.G.5    Orchard, K.H.6
  • 41
    • 29244489245 scopus 로고    scopus 로고
    • The neurobeachin gene spans the common fragile site FRA13A
    • DOI 10.1007/s00439-005-0083-z
    • Savelyeva L, Sagulenko E, Schmitt JG, Schwab M. The neurobeachin gene spans the common fragile site FRA13A. Hum Genet 2006;118:551-8. (Pubitemid 41825127)
    • (2006) Human Genetics , vol.118 , Issue.5 , pp. 551-558
    • Savelyeva, L.1    Sagulenko, E.2    Schmitt, J.G.3    Schwab, M.4
  • 42
    • 0034655131 scopus 로고    scopus 로고
    • WWOX, a novel WW domain-containing protein mapping to human chromosome 16q23.3-24.1, a region frequently affected in breast cancer
    • Bednarek AK, Laflin KJ, Daniel RL, Liao Q, Hawkins KA, Aldaz CM. WWOX, a novel WW domain-containing protein mapping to human chromosome 16q23.3-24.1, a region frequently affected in breast cancer. Cancer Res 2000;60:2140-5. (Pubitemid 30225175)
    • (2000) Cancer Research , vol.60 , Issue.8 , pp. 2140-2145
    • Bednarek, A.K.1    Laflin, K.J.2    Daniel, R.L.3    Liao, Q.4    Hawkins, K.A.5    Aldaz, C.M.6
  • 43
    • 71249098177 scopus 로고    scopus 로고
    • Frequent epigenetic inactivation of the receptor tyrosine kinase EphA5 by promoter methylation in human breast cancer
    • Fu DY, Wang ZM, Wang BL, Chen L, Yang WT, Shen ZZ, et al. Frequent epigenetic inactivation of the receptor tyrosine kinase EphA5 by promoter methylation in human breast cancer. Hum Pathol 2010;41:48-58.
    • (2010) Hum Pathol , vol.41 , pp. 48-58
    • Fu, D.Y.1    Wang, Z.M.2    Wang, B.L.3    Chen, L.4    Yang, W.T.5    Shen, Z.Z.6
  • 46
    • 65949104846 scopus 로고    scopus 로고
    • Identification of copy number abnormalities and inactivating mutations in two negative regulators of nuclear factorkappaB signaling pathways in Waldenstroms macroglobulinemia
    • Braggio E, Keats JJ, Leleu X, Van Wier S, Jimenez-Zepeda VH, Valdez R, et al. Identification of copy number abnormalities and inactivating mutations in two negative regulators of nuclear factorkappaB signaling pathways in Waldenstroms macroglobulinemia. Cancer Res 2009;69:3579-88.
    • (2009) Cancer Res , vol.69 , pp. 3579-3588
    • Braggio, E.1    Keats, J.J.2    Leleu, X.3    Van Wier, S.4    Jimenez-Zepeda, V.H.5    Valdez, R.6
  • 47
    • 50049117225 scopus 로고    scopus 로고
    • Identification of candidate tumour suppressor gene loci for Hodgkin and Reed-Sternberg cells by characterisation of homozygous deletions in classical Hodgkin lymphoma cell lines
    • Giefing M, Arnemann J, Martin-Subero JI, Nieländer I, Bug S, Hartmann S, et al. Identification of candidate tumour suppressor gene loci for Hodgkin and Reed-Sternberg cells by characterisation of homozygous deletions in classical Hodgkin lymphoma cell lines. Br J Haematol 2008;142:916-24.
    • (2008) Br J Haematol , vol.142 , pp. 916-924
    • Giefing, M.1    Arnemann, J.2    Martin-Subero, J.I.3    Nieländer, I.4    Bug, S.5    Hartmann, S.6
  • 50
    • 79960631098 scopus 로고    scopus 로고
    • Bcl-2 is a better therapeutic target than c-Myc, but attacking both could be a more effective treatment strategy for B-cell lymphoma with concurrent Bcl-2 and c-Myc overexpression
    • Sasaki N, Kuroda J, Nagoshi H, Yamamoto M, Kobayashi S, Tsutsumi Y, et al. Bcl-2 is a better therapeutic target than c-Myc, but attacking both could be a more effective treatment strategy for B-cell lymphoma with concurrent Bcl-2 and c-Myc overexpression. Exp Hematol 2011;39:817-28.
    • (2011) Exp Hematol , vol.39 , pp. 817-828
    • Sasaki, N.1    Kuroda, J.2    Nagoshi, H.3    Yamamoto, M.4    Kobayashi, S.5    Tsutsumi, Y.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.