The activities of 5α-reductase and 17,20-lyase determine the direction through androgen synthesis pathways in patients with 21-hydroxylase deficiency

Steroids

Volumn 77, Issue 13, 2012, Pages 1391-1397

  Kamrath, Clemens ^a   Hartmann, Michaela F ^a   Remer, Thomas ^b   Wudy, Stefan A ^a  

^a JUSTUS LIEBIG UNIVERSITY   (Germany)

^b UNIVERSITY OF BONN   (Germany)

Author keywords

17 Hydroxyallopregnanolone; 17 Diol 20 one; 17,20 Lyase; 21 Hydroxylase deficiency; 5 Pregnane 3 ; 5 Reductase; Backdoor pathway

Indexed keywords

17ALPHA HYDROXYALLOPREGNANOLONE; ANDROSTERONE; CYTOCHROME P450 17; CYTOCHROME P450 17A1; STEROID 17ALPHA MONOOXYGENASE; STEROID 21 MONOOXYGENASE; STEROID 5ALPHA REDUCTASE; UNCLASSIFIED DRUG;

ADOLESCENT; ADULT; ANDROGEN SYNTHESIS; ARTICLE; CHILD; CONTROLLED STUDY; ENZYME ACTIVITY; FEMALE; GAS CHROMATOGRAPHY; HUMAN; INFANT; MAJOR CLINICAL STUDY; MALE; MASS SPECTROMETRY; NEWBORN; PRESCHOOL CHILD; SCHOOL CHILD; STEROID 21 MONOOXYGENASE DEFICIENCY;

3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE; ADOLESCENT; ADRENAL HYPERPLASIA, CONGENITAL; ANDROGENS; CHILD; CHILD, PRESCHOOL; FEMALE; HUMANS; INFANT; INFANT, NEWBORN; MALE; STEROID 17-ALPHA-HYDROXYLASE; YOUNG ADULT;

PYRONIA TITHONUS;

EID: 84867131494     PISSN: 0039128X     EISSN: 18785867     Source Type: Journal    
DOI: 10.1016/j.steroids.2012.08.001     Document Type: Article

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