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Volumn 9, Issue 4, 2012, Pages 401-408

Effects of lead exposure on DNA damage and apoptosis in reproductive and vital organs in female rabbits

Author keywords

Apoptosis; DNA damage; Lead acetate; Pathological changes; Rabbits

Indexed keywords

ANIMALIA; ORYCTOLAGUS CUNICULUS;

EID: 84867119019     PISSN: 19926197     EISSN: 19998163     Source Type: Journal    
DOI: 10.5829/idosi.gv.2012.9.4.6585     Document Type: Article
Times cited : (22)

References (55)
  • 1
    • 0003815871 scopus 로고
    • Atsdr, Publ no PB93-182475. Agency for toxic substances and disease registry, Atlanta, GA
    • Atsdr, 1993. Toxicological profile for lead. Publ no PB93-182475. Agency for toxic substances and disease registry, Atlanta, GA.
    • (1993) Toxicological Profile for Lead
  • 2
    • 34548455387 scopus 로고    scopus 로고
    • Sources and characteristics of lead pollution in the urban environment of Guangzhou
    • Duzgoren-Aydin, N.S., 2007. Sources and characteristics of lead pollution in the urban environment of Guangzhou. Sci. Total Environ., 385: 182-195.
    • (2007) Sci. Total Environ , vol.385 , pp. 182-195
    • Duzgoren-Aydin, N.S.1
  • 4
    • 0028296692 scopus 로고
    • Lipoperoxidative damage on lead exposure in rat brain and its implications on membrane bound enzymes
    • Sandhir, R., D. Julka and K.D. Gill, 1994. Lipoperoxidative damage on lead exposure in rat brain and its implications on membrane bound enzymes. Pharmacol.Toxicol., 74: 66-71.
    • (1994) Pharmacol.Toxicol , vol.74 , pp. 66-71
    • Sandhir, R.1    Julka, D.2    Gill, K.D.3
  • 5
    • 33745903081 scopus 로고    scopus 로고
    • Lead toxicity part II: The role of free radical damage and the use of antioxidants in the pathology and treatment of lead toxicity
    • Patrick, L., 2006. Lead toxicity part II: the role of free radical damage and the use of antioxidants in the pathology and treatment of lead toxicity. Altern. Med. Rev., 11: 114-127.
    • (2006) Altern. Med. Rev , vol.11 , pp. 114-127
    • Patrick, L.1
  • 6
    • 0141560468 scopus 로고    scopus 로고
    • Brain barrier systems: A new frontier in metal neurotoxicological research
    • Zheng, W., M. Aschner and J.F. Ghersi-Egea, 2003. Brain barrier systems: a new frontier in metal neurotoxicological research. Toxicol. Appl. Pharmacol., 192: 1-11.
    • (2003) Toxicol. Appl. Pharmacol , vol.192 , pp. 1-11
    • Zheng, W.1    Aschner, M.2    Ghersi-Egea, J.F.3
  • 7
    • 84859057417 scopus 로고    scopus 로고
    • Same reproductive and blood parameters of female rabbit given different doses of lead acetate
    • Mohamed, W.S., A.M. Hamam and M.M. El-Tohamy, 1998. Same reproductive and blood parameters of female rabbit given different doses of lead acetate. J. Union Arab Biol (Zoology), 9: 385-397.
    • (1998) J. Union Arab Biol (Zoology) , vol.9 , pp. 385-397
    • Mohamed, W.S.1    Hamam, A.M.2    El-Tohamy, M.M.3
  • 8
    • 0033377553 scopus 로고    scopus 로고
    • Lead acetate genotoxicity in mice
    • Fahmy, M.A., 1999. Lead acetate genotoxicity in mice. Cytologia, 64: 357-365.
    • (1999) Cytologia , vol.64 , pp. 357-365
    • Fahmy, M.A.1
  • 10
    • 84859049499 scopus 로고    scopus 로고
    • Some studies on the toxic effects of prolonged lead exposure in male rabbits: Chromosomal and testicular alterations
    • Ahmed, Y.F., K. Gh. M. Mahmoud, A.A. Farghaly, M.A. Abo-Zeid and E.M. Ismail, 2012. Some studies on the toxic effects of prolonged lead exposure in male rabbits: Chromosomal and testicular alterations. Global Veterinaria, 8: 360-366.
    • (2012) Global Veterinaria , vol.8 , pp. 360-366
    • Ahmed, Y.F.1    Mahmoud, K.G.M.2    Farghaly, A.A.3    Abo-Zeid, M.A.4    Ismail, E.M.5
  • 11
    • 29144491952 scopus 로고    scopus 로고
    • The evaluation of micronucleus frequency by acridine orange fluorescent staining in peripheral blood of rats treated with lead acetate
    • Celik, A., O. Ogenler and U. Comelekoglu, 2005. The evaluation of micronucleus frequency by acridine orange fluorescent staining in peripheral blood of rats treated with lead acetate. Mutagenesis, 20: 411-415.
    • (2005) Mutagenesis , vol.20 , pp. 411-415
    • Celik, A.1    Ogenler, O.2    Comelekoglu, U.3
  • 12
    • 0023678988 scopus 로고
    • Lead induced changes in the stabilization of the mouse sperm chromatin
    • Johansson, L. and C.E. Pellicciari, 1988. Lead induced changes in the stabilization of the mouse sperm chromatin. Toxicology, 51: 11-24.
    • (1988) Toxicology , vol.51 , pp. 11-24
    • Johansson, L.1    Pellicciari, C.E.2
  • 13
    • 0025230371 scopus 로고
    • Indirect mechanism of lead induced genotoxicity in cultured mammalian cells
    • Hartwig, A., R. Schlepegrell and D. Beyersmann, 1990. Indirect mechanism of lead induced genotoxicity in cultured mammalian cells. Mutat. Res., 241: 75-82.
    • (1990) Mutat. Res , vol.241 , pp. 75-82
    • Hartwig, A.1    Schlepegrell, R.2    Beyersmann, D.3
  • 14
    • 0016254114 scopus 로고
    • Heavy metal toxicities
    • Bremer, I., 1974. Heavy metal toxicities. Rev. Biophys., 7: 75-124.
    • (1974) Rev. Biophys , vol.7 , pp. 75-124
    • Bremer, I.1
  • 15
    • 0021687518 scopus 로고
    • Maturation of resistance to lead encephalopathy; cellular and sub-cellular mechanisms
    • Holtzman, D., C. Devries, H. Nguyen, J. Oslon and K. Bensch, 1984. Maturation of resistance to lead encephalopathy; cellular and sub-cellular mechanisms. Neurotoxicology, 5: 97-124.
    • (1984) Neurotoxicology , vol.5 , pp. 97-124
    • Holtzman, D.1    Devries, C.2    Nguyen, H.3    Oslon, J.4    Bensch, K.5
  • 18
    • 0034646966 scopus 로고    scopus 로고
    • Genotoxic effect of lead nitrate on mice using SCGE (comet assay)
    • Devi, K.D., B.S. Banu, P. Grover and K. Jamil, 2000. Genotoxic effect of lead nitrate on mice using SCGE (comet assay). Toxicology, 145: 195-201.
    • (2000) Toxicology , vol.145 , pp. 195-201
    • Devi, K.D.1    Banu, B.S.2    Grover, P.3    Jamil, K.4
  • 19
    • 0003260364 scopus 로고    scopus 로고
    • Rodentia and Lagomorpha
    • Shore, R.F., Rattner, B.A. (Eds.), Wiley, Chichester. New York, Weinheim, Brisbane, Singapore, Toronto
    • Sheffield, S.R., K. Sawicka-Kapusta, J.B. Cohen and B.A. Rattner, 2001. Rodentia and Lagomorpha. In: Shore, R.F., Rattner, B.A. (Eds.), Ecotoxicology of Wild Mammals. Wiley, Chichester. New York, Weinheim, Brisbane, Singapore, Toronto, pp: 215-314.
    • (2001) Ecotoxicology of Wild Mammals , pp. 215-314
    • Sheffield, S.R.1    Sawicka-Kapusta, K.2    Cohen, J.B.3    Rattner, B.A.4
  • 20
    • 3142683772 scopus 로고    scopus 로고
    • Histopathological changes in the liver, kidneys and testes of bank voles environmentally exposed to heavy metal emissions from the steelworks and zinc smelter in Poland
    • Damek-Poprawa, M. and K. Sawicka-Kapusta, 2004. Histopathological changes in the liver, kidneys and testes of bank voles environmentally exposed to heavy metal emissions from the steelworks and zinc smelter in Poland. Environ. Res., 96: 72-78.
    • (2004) Environ. Res , vol.96 , pp. 72-78
    • Damek-Poprawa, M.1    Sawicka-Kapusta, K.2
  • 21
    • 0242318892 scopus 로고    scopus 로고
    • Ultrastructural modifications in the mitochondrion of mouse Sertoli cells after inhalation of lead, cadmium or lead-cadmium mixture
    • Bizarro, P., S. Acevedo, G. Nin'o-Cabrera, P. Mussali- Galante, F. Pasos, M.R. Avila-Costa and T.I. Fortoul, 2003. Ultrastructural modifications in the mitochondrion of mouse Sertoli cells after inhalation of lead, cadmium or lead-cadmium mixture. Reprod Toxicol., 17: 561-566.
    • (2003) Reprod Toxicol , vol.17 , pp. 561-566
    • Bizarro, P.1    Acevedo, S.2    Nin'o-Cabrera, G.3    Mussali-Galante, P.4    Pasos, F.5    Avila-Costa, M.R.6    Fortoul, T.I.7
  • 23
    • 42949089904 scopus 로고    scopus 로고
    • Lead hepatotoxicity and potential health effects
    • Mudipalli, A., 2007. Lead hepatotoxicity and potential health effects. Indian J. Med. Res., 126: 518-27.
    • (2007) Indian J. Med. Res , vol.126 , pp. 518-527
    • Mudipalli, A.1
  • 24
    • 0028364510 scopus 로고
    • Comparative investigations of the genotoxic effects of metals in the single cell gel (SCG) assay and the sister chromatid exchange (SCE) test
    • Hartman, A. and G. Speit, 1994. Comparative investigations of the genotoxic effects of metals in the single cell gel (SCG) assay and the sister chromatid exchange (SCE) test. Environ. Mol. Mutagen., 23: 299-305.
    • (1994) Environ. Mol. Mutagen , vol.23 , pp. 299-305
    • Hartman, A.1    Speit, G.2
  • 25
    • 0027142303 scopus 로고
    • The effects of Cu2_ andPb2_ on the solution structure of calf thymus DNA: DNA condensation and denaturation studied by Fourier Transform IR difference spectroscopy
    • Tajmir-Riahi, H.A., M. Naoui and R. Ahmad, 1993. The effects of Cu2_ andPb2_ on the solution structure of calf thymus DNA: DNA condensation and denaturation studied by Fourier Transform IR difference spectroscopy. Biopolymers, 33: 1819-1827.
    • (1993) Biopolymers , vol.33 , pp. 1819-1827
    • Tajmir-Riahi, H.A.1    Naoui, M.2    Ahmad, R.3
  • 28
    • 0028598790 scopus 로고
    • Newcastle disease virus induced apoptosis in chicken peripheral blood lymphocytes
    • Lam, K.M. and A.C. Vasconcelos, 1994. Newcastle disease virus induced apoptosis in chicken peripheral blood lymphocytes. Vet Immunol Immunopathol., 44: 4556.
    • (1994) Vet Immunol Immunopathol , vol.44 , pp. 4556
    • Lam, K.M.1    Vasconcelos, A.C.2
  • 30
    • 78049455935 scopus 로고    scopus 로고
    • Protective role of flaxseed oil against lead acetate induced oxidative stress in testes of adult rats
    • Abdel Moniem, A.E., M.A. Dkhil and S. Al-Quraishy, 2010. Protective role of flaxseed oil against lead acetate induced oxidative stress in testes of adult rats. African Journal of Biotechnology, 9: 7216-7223.
    • (2010) African Journal of Biotechnology , vol.9 , pp. 7216-7223
    • Abdel, M.A.E.1    Dkhil, M.A.2    Al-Quraishy, S.3
  • 33
    • 0028798434 scopus 로고
    • Oxidative mechanisms in the toxicity of metal ions
    • Stohs, S.J. and D. Bagchi, 1995. Oxidative mechanisms in the toxicity of metal ions. Free Radic. Biol. Med., 18: 321-336.
    • (1995) Free Radic. Biol. Med , vol.18 , pp. 321-336
    • Stohs, S.J.1    Bagchi, D.2
  • 34
    • 0026457867 scopus 로고
    • Mutagenesis and comutagenesis by lead compounds
    • Roy, N.K. and T.G. Rossman, 1992. Mutagenesis and comutagenesis by lead compounds. Mutat. Res., 298: 97-103.
    • (1992) Mutat. Res , vol.298 , pp. 97-103
    • Roy, N.K.1    Rossman, T.G.2
  • 35
    • 0042170224 scopus 로고    scopus 로고
    • Lead acetate induced cytotoxicity in male germinal cells of Swiss mice
    • Acharya, U.R., S. Acharya and M. Mishra, 2003. Lead acetate induced cytotoxicity in male germinal cells of Swiss mice. Ind. Health, 41: 291-294.
    • (2003) Ind. Health , vol.41 , pp. 291-294
    • Acharya, U.R.1    Acharya, S.2    Mishra, M.3
  • 36
    • 0026684913 scopus 로고
    • Metal carcinogenesis: Mechanistic implications
    • Snow, E.T., 1992. Metal carcinogenesis: mechanistic implications. Pharmacol. Ther., 53: 31-65.
    • (1992) Pharmacol. Ther , vol.53 , pp. 31-65
    • Snow, E.T.1
  • 37
    • 77956793774 scopus 로고    scopus 로고
    • Toxicological approach in chronic exposure to lead on reproductive functions in female rats (Rattus Norvegicus)
    • Dhir, V. and P. Dhand, 2010. Toxicological approach in chronic exposure to lead on reproductive functions in female rats (Rattus Norvegicus) Toxicol Int., 17: 1-7.
    • (2010) Toxicol Int , vol.17 , pp. 1-7
    • Dhir, V.1    Dhand, P.2
  • 38
    • 18744409350 scopus 로고    scopus 로고
    • Cytotoxic effects of lead on the endocrine and exocrine sexual function of pubescent male and female rats. Demonstration of apoptotic activity
    • Gorbel, F., M. Boujelbene, F. Makni-Ayadi, F. Guermazi, F. Croute, J.P. Soleilhavoup and A. el Feki, 2002. Cytotoxic effects of lead on the endocrine and exocrine sexual function of pubescent male and female rats. Demonstration of apoptotic activity. C R Biol., 325: 927-940.
    • (2002) C R Biol , vol.325 , pp. 927-940
    • Gorbel, F.1    Boujelbene, M.2    Makni-Ayadi, F.3    Guermazi, F.4    Croute, F.5    Soleilhavoup, J.P.6    el Feki, A.7
  • 39
    • 77956801270 scopus 로고
    • Anatomical methods in cell death
    • Schwartz LM, Osborne BA, editors. London: Academic Press
    • Kerr, J.F.R., G.G. Gobé, C.M. Winterford and V. Harmon, 1995. Anatomical methods in cell death. In: Schwartz LM, Osborne BA, editors. Cell death. London: Academic Press, pp: 1-26.
    • (1995) Cell death , pp. 1-26
    • Kerr, J.F.R.1    Gobé, G.G.2    Winterford, C.M.3    Harmon, V.4
  • 40
    • 0034953632 scopus 로고    scopus 로고
    • Apoptosis-regulating proteins as targets for drug discovery
    • Reed, J.C., 2001. Apoptosis-regulating proteins as targets for drug discovery. Trends in Molecular Medicine, 7: 314-319.
    • (2001) Trends in Molecular Medicine , vol.7 , pp. 314-319
    • Reed, J.C.1
  • 41
    • 1442349834 scopus 로고    scopus 로고
    • Comparative measurement of spontaneous apoptosis in pediatric acute leukemia by different techniques
    • Savitskiy, V.P., T. Shman and M.P. Potapnev, 2003. Comparative measurement of spontaneous apoptosis in pediatric acute leukemia by different techniques. Cytometry, 56: 16-22.
    • (2003) Cytometry , vol.56 , pp. 16-22
    • Savitskiy, V.P.1    Shman, T.2    Potapnev, M.P.3
  • 42
    • 0026741036 scopus 로고
    • Histopathological and cytochemical changes induced in the liver of golden fish Carassius carassius var. auratusby short-term exposure to lead
    • Bolognani, Fantin, A.M., A. Franchini, P. Trevisan and A. Pederzoli, 1992. Histopathological and cytochemical changes induced in the liver of golden fish Carassius carassius var. auratusby short-term exposure to lead. Acta Histochem., 92: 228-235.
    • (1992) Acta Histochem , vol.92 , pp. 228-235
    • Bolognani, F.A.M.1    Franchini, A.2    Trevisan, P.3    Pederzoli, A.4
  • 43
    • 85173816409 scopus 로고    scopus 로고
    • Metals and biological membranes
    • Chang,L. (Ed.), CRC Press Inc., Boca Raton, FL
    • Foulkes, E.C., 1996. Metals and biological membranes. In: Chang,L. (Ed.), Toxicology of Metals. CRC Press Inc., Boca Raton, FL, pp: 133-143.
    • (1996) Toxicology of Metals , pp. 133-143
    • Foulkes, E.C.1
  • 44
    • 0013404659 scopus 로고    scopus 로고
    • Wildlife animals as sentinels to human health due to environmental exposure to heavy metals
    • Proceedings of the 11th Annual meeting, SETAC Europe, 6-10 May, Soc. Environ.Toxicol. Chem., Madrid
    • Pereira, R., M.L. Pereira, R. Ribeiro and F. Goncalves, 2001. Wildlife animals as sentinels to human health due to environmental exposure to heavy metals. In: Abstract Book. In: Proceedings of the 11th Annual meeting, SETAC Europe, 6-10 May, Soc. Environ.Toxicol. Chem., Madrid, pp: 108.
    • (2001) Abstract Book , pp. 108
    • Pereira, R.1    Pereira, M.L.2    Ribeiro, R.3    Goncalves, F.4
  • 47
    • 0020597978 scopus 로고
    • Acid fast inclusions in osteoclasts of a lead poisoned dog
    • Hamir, A.N., N.D. Sullivan and P.D. Handson, 1983. Acid fast inclusions in osteoclasts of a lead poisoned dog. Vet. Record., 112: 505.
    • (1983) Vet. Record , vol.112 , pp. 505
    • Hamir, A.N.1    Sullivan, N.D.2    Handson, P.D.3
  • 48
    • 0033831298 scopus 로고    scopus 로고
    • Lead as a carcinogen: Experimental evidence and mechanisms of action
    • Silbergeld, E.K., M. Waalkes and J.M. Rice, 2000. Lead as a carcinogen: experimental evidence and mechanisms of action. Am. J. Ind. Med., 38: 316-23.
    • (2000) Am. J. Ind. Med , vol.38 , pp. 316-323
    • Silbergeld, E.K.1    Waalkes, M.2    Rice, J.M.3
  • 49
    • 0029917115 scopus 로고    scopus 로고
    • A longitudinal study of low-level lead exposure and impairment of renal function
    • Kim, R., A. Rotnitzky, D. Sparrow, S.T. Weiss, C. Wager and H. Hu, 1996. A longitudinal study of low-level lead exposure and impairment of renal function. JAMA, 275: 1177-1181.
    • (1996) JAMA , vol.275 , pp. 1177-1181
    • Kim, R.1    Rotnitzky, A.2    Sparrow, D.3    Weiss, S.T.4    Wager, C.5    Hu, H.6
  • 50
    • 0030815815 scopus 로고    scopus 로고
    • Renal effects of environmental and occupational lead exposure
    • Loghman-Adham, M., 1997. Renal effects of environmental and occupational lead exposure. Environ. Health Perspect., 105: 928-938.
    • (1997) Environ. Health Perspect , vol.105 , pp. 928-938
    • Loghman-Adham, M.1
  • 51
    • 64849100573 scopus 로고    scopus 로고
    • Effects of lead on hepatic antioxidant status and transcription of superoxide dismutase gene in pigs
    • Yu, D.Y., W.F. Li, B. Deng and X.F. Mao, 2008. Effects of lead on hepatic antioxidant status and transcription of superoxide dismutase gene in pigs. Biol Trace Elem Res., 126(1-3): 121-128.
    • (2008) Biol Trace Elem Res , vol.126 , Issue.1-3 , pp. 121-128
    • Yu, D.Y.1    Li, W.F.2    Deng, B.3    Mao, X.F.4
  • 52
    • 67651174721 scopus 로고    scopus 로고
    • A comparison of the effect of lead nitrate on rat liver chromatin, DNA and histone proteins in solution
    • Rabbani-Chadegani, A., S. Abdosamadi, N. Fani and S. Mohammadian, 2009. A comparison of the effect of lead nitrate on rat liver chromatin, DNA and histone proteins in solution. Arch Toxicol., 83: 565-70.
    • (2009) Arch Toxicol , vol.83 , pp. 565-570
    • Rabbani-Chadegani, A.1    Abdosamadi, S.2    Fani, N.3    Mohammadian, S.4
  • 53
    • 0038799736 scopus 로고    scopus 로고
    • Oxidative DNA damage: Mechanisms, mutation and disease
    • Cooke, M.S., M.D. Evans, M. Dizdaroglu and J. Lunec, 2003. Oxidative DNA damage: mechanisms, mutation and disease. Faseb J., 17: 1195-214.
    • (2003) Faseb J , vol.17 , pp. 1195-1214
    • Cooke, M.S.1    Evans, M.D.2    Dizdaroglu, M.3    Lunec, J.4
  • 54
    • 0033214057 scopus 로고    scopus 로고
    • Superoxide dismutase in normal cycling human ovaries: Immunohistochemical localization and characterization
    • Suzuki, T., N. Sugino, T. Fukaya, S. Sugiyama, T. Uda, R. Takaya, A. Yajima and H. Sasano, 1999. Superoxide dismutase in normal cycling human ovaries: immunohistochemical localization and characterization. Fertil Steril., 72: 720-726.
    • (1999) Fertil Steril , vol.72 , pp. 720-726
    • Suzuki, T.1    Sugino, N.2    Fukaya, T.3    Sugiyama, S.4    Uda, T.5    Takaya, R.6    Yajima, A.7    Sasano, H.8
  • 55
    • 0027214352 scopus 로고
    • Oxygen radicals-superoxide dismutase system and reproduction medicine
    • Ishikawa, M., 1993. Oxygen radicals-superoxide dismutase system and reproduction medicine. Nippon Sanka Fujinka Gakkai Zasshi., 45: 842-848.
    • (1993) Nippon Sanka Fujinka Gakkai Zasshi , vol.45 , pp. 842-848
    • Ishikawa, M.1


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