Synthesis of multiply deuterated 3- and 21-monosulfates of allo-tetrahydrocorticosteroids as internal standards for mass spectrometry

Steroids

Volumn 77, Issue 13, 2012, Pages 1423-1437

  Mitamura, Kuniko ^a   Mabuchi, Takayuki ^a   Nagae, Kaori ^a   Nakajima, Masataka ^a   Matsumoto, Rina ^a   Fujioka, Sachi ^a   Sato, Kanta ^a   Satoh, Rika ^b   Iida, Takashi ^b   Ogawa, Shoujiro ^c   Hofmann, Alan F ^d   Ikegawa, Shigeo ^a  

^a KINKI UNIVERSITY   (Japan)

^b NIHON UNIVERSITY   (Japan)

^c TOKYO UNIVERSITY OF SCIENCE   (Japan)

^d UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

Author keywords

Electrospray ionization; Hydrogen deuterium exchange; LC MS; Multiple deuteration; Sodium borodeuteride; Walden inversion

Indexed keywords

17,20 20,21 BISMETHYLENEDIOXY 11BETA TRIMETHYLSILYLOXY 5ALPHA PREGNAN 3BETA OL; 17,20 20,21 BISMETHYLENEDIOXY 11BETA TRIMETHYLSILYLOXYPREGN 5 EN 3BETA OL; 17,20 20,21 BISMETHYLENEDIOXY 2ALPHA,3ALPHA EPOXY 5ALPHA PREGNANE; 17,20 20,21 BISMETHYLENEDIOXY 5ALPHA PREGNAN 3 ONE; 17,20 20,21 BISMETHYLENEDIOXY 5ALPHA PREGNAN 3ALPHA OL; 17,20 20,21 BISMETHYLENEDIOXY 5ALPHA PREGNAN 3ALPHA YL ACETATE; 17,20 20,21 BISMETHYLENEDIOXY 5ALPHA PREGNAN 3BETA OL; 17,20 20,21 BISMETHYLENEDIOXY 5ALPHA PREGNAN 3BETA YL 4 TOLUENESULFONATE; 17,20 20,21 BISMETHYLENEDIOXY 5ALPHA PREGNAN 3BETA,11BETA DIOL; 17,20 20,21 BISMETHYLENEDIOXYPREGN 5 EN 3BETA OL; 21 MONOSULFATE DERIVATIVE; 3 MONOSULFATE DERIVATIVE; 3BETA HYDROXY GROUP; 5ALPHA 11 KETOSTEROID; 5ALPHA 3 KETOSTEROID; ALCOHOL; ALLO TETRAHYDROCORTISONE; ALLOTETRAHYDROC 11 DEOXYCORTISOL; ALLOTETRAHYDROCORTISOL; CARBENE; CARBON; DEUTERIUM; HYDROCORTISONE; HYDROFLUORIC ACID; HYDROXYL GROUP; OXOSTEROID; SULFATE; SULFUR TRIOXIDE TRIMETHYLAMINE; TRIMETHYLAMINE; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ARTICLE; CHEMICAL STRUCTURE; CONTROLLED STUDY; DEUTERIUM HYDROGEN EXCHANGE; EPIMERIZATION; ISOTOPE LABELING; MASS SPECTROMETRY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; REDUCTION; STANDARD; SULFATION; SYNTHESIS;

ADRENAL CORTEX HORMONES; CHEMISTRY TECHNIQUES, SYNTHETIC; MASS SPECTROMETRY; REFERENCE STANDARDS; SULFATES;

EID: 84867114703     PISSN: 0039128X     EISSN: 18785867     Source Type: Journal    
DOI: 10.1016/j.steroids.2012.08.007     Document Type: Article

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