Mechanistic studies on CymD: A tryptophan reverse N-prenyltransferase

Biochemistry

Volumn 51, Issue 39, 2012, Pages 7733-7739

  Qian, Qi ^a   Schultz, Andrew W ^b   Moore, Bradley S ^b   Tanner, Martin E ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AZA-COPE REARRANGEMENT; CARBOCATIONS; CYCLIC PEPTIDES; DIPHOSPHATES; INDOLE RINGS; ISOTOPE EXCHANGE; MAXIMAL RATES; MECHANISTIC STUDIES; NUCLEOPHILIC ATTACK; POSITIVE CHARGES; PRENYLTRANSFERASE; RATE LIMITING; SOLVENT KINETIC ISOTOPE EFFECTS;

AMINO ACIDS; BIOCHEMISTRY; CATALYSIS; NITROGEN; REACTION KINETICS;

ISOTOPES;

3 (FLUOROMETHYL) 2 BUTEN 1 YL DIPHOSPHATE; 4 FLUOROTRYPTOPHAN; DIMETHYLALLYL DIPHOSPHATE; DIMETHYLALLYLTRANSFERASE; INDOLE; ISOTOPE; N PRENYLTRANSFERASE; NITROGEN; PHOSPHORUS DERIVATIVE; PRENYLTRANSFERASE CYMD; SOLVENT; TRYPTOPHAN; TRYPTOPHAN DERIVATIVE; UNCLASSIFIED DRUG;

ALKYLATION; ANIMAL CELL; ARTICLE; CARBONYLATION; CATALYSIS; CHEMICAL REACTION; CONTROLLED STUDY; COPE REARRANGEMENT; CYCLOADDITION; DEPROTONATION; ENZYME KINETICS; FLOW KINETICS; ION EXCHANGE; IONIZATION; ISOTOPE LABELING; NONHUMAN; NUCLEOPHILICITY; POSITIONAL ISOTOPE EXCHANGE; PRIORITY JOURNAL; PROTEIN PRENYLATION; PROTEIN SYNTHESIS; PROTON TRANSPORT; SUBSTITUTION REACTION;

ACTINOBACTERIA; DIMETHYLALLYLTRANSTRANSFERASE; HALOGENATION; HEMITERPENES; INDOLES; KINETICS; ORGANOPHOSPHORUS COMPOUNDS; PRENYLATION; PROTONS; TRYPTOPHAN;

EID: 84867093437     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi3009054     Document Type: Article

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