Poly-l-lysine-coated magnetic nanoparticles as intracellular actuators for neural guidance

International Journal of Nanomedicine

Volumn 7, Issue , 2012, Pages 3155-3166

  Riggio, Cristina ^a   Calatayud, Maria Pilar ^b   Hoskins, Clare ^c   Pinkernelle, Josephine ^d   Sanz, Beatriz ^b   Torres, Teobaldo Enrique ^b   Ibarra, Manuel Ricardo ^b   Wang, Lijun ^c   Keilhoff, Gerburg ^d   Goya, Gerardo Fabian ^b   Raffa, Vittoria ^a,e   Cuschieri, Alfred ^a,c  

^a SCUOLA SUPERIORE SANT ANNA   (Italy)

^b UNIVERSITY OF ZARAGOZA   (Spain)

^c UNIVERSITY OF DUNDEE   (United Kingdom)

^d OTTO VON GUERICKE UNIVERSITY   (Germany)

^e UNIVERSITY OF PISA   (Italy)

Author keywords

Actuator; Magnetic nanoparticle; Migration; Neural regeneration

Indexed keywords

IRON OXIDE; MAGNETIC NANOPARTICLE; POLYLYSINE; REACTIVE OXYGEN METABOLITE;

ARTICLE; CANCER CELL CULTURE; CELL LABELING; CELL MEDIATED CYTOTOXICITY; CELL MIGRATION; CELL PROLIFERATION; CELL VIABILITY; CELLULAR DISTRIBUTION; HUMAN; HUMAN CELL; HYDROLYSIS; MAGNETIC FIELD; MATERIAL COATING; NEUROBLASTOMA CELL; PERIPHERAL NERVOUS SYSTEM; SCANNING ELECTRON MICROSCOPY; SCHWANN CELL; TRANSMISSION ELECTRON MICROSCOPY;

ANALYSIS OF VARIANCE; ANIMALS; CELL LINE, TUMOR; CELL MEMBRANE; CELL MOVEMENT; CELL SURVIVAL; CELLS, CULTURED; HUMANS; IRON; MAGNETITE NANOPARTICLES; NEUROBLASTOMA; NEURONS; PARTICLE SIZE; POLYLYSINE; RATS; SCHWANN CELLS; STATIC ELECTRICITY;

MAMMALIA;

EID: 84867083141     PISSN: 11769114     EISSN: 11782013     Source Type: Journal    
DOI: 10.2147/ijn.s28460     Document Type: Article

References (29)

1. Gao JH, Gu HW, Xu B. Multifunctional magnetic nanoparticles: design, synthesis, and biomedical applications. Accounts Chem Res. 2009;42:1097-1107.
2. Sun C, Lee JSH, Zhang MQ. Magnetic nanoparticles in MR imaging and drug delivery. Adv Drug Deliv Rev. 2008;60:1252-1265.
3. Veiseh O, Gunn JW, Zhang MQ. Design and fabrication of magnetic nanoparticles for targeted drug delivery and imaging. Adv Drug Deliv Rev. 2010;62:284-304.
4. Goya GF, Grazu V, Ibarra MR. Magnetic nanoparticles for cancer therapy. Curr Nanosci. 2008;4:1-16
5. Gupta AK, Naregalkar RR, Vaidya VD, Gupta M. Recent advances on surface engineering of magnetic iron oxide nanoparticles and their biomedical applications. Nanomedicine (Lond). 2007;2:23-39.
6. Gupta AK, Gupta M. Synthesis and surface engineering of iron oxide nanoparticles for biomedical applications. Biomaterials. 2005;26:3995-4021.
7. Laurent S, Forge D, Port M, et al. Magnetic iron oxide nanoparticles: Synthesis, stabilization, vectorization, physicochemical characterizations, and biological applications. Chem Rev. 2008;108:2064-2110.
8. Misra RDK. Magnetic nanoparticle carrier for targeted drug delivery: perspective, outlook and design. Mater Sci Tech. 2008;24:1011-1019.
9. McCarthy JR, Kelly KA, Sun EY, Weissleder R. Targeted delivery of multifunctional magnetic nanoparticles. Nanomedicine (Lond). 2007;2:153-167.
10. McCarthy JR, Weissleder R. Multifunctional magnetic nanoparticles for targeted imaging and therapy. Adv Drug Deliv Rev. 2008;60:1241-1251.
11. Wilhelm C, Gazeau F. Universal cell labelling with anionic magnetic nanoparticles. Biomaterials. 2008;29:3161-3174.
12. Wilson MW, Kerlan RK Jr, Fidelman NA, et al. Hepatocellular carcinoma: Regional therapy with a magnetic targeted carrier bound to doxorubicin in a dual MR imaging/conventional angiography suite - initial experience with four patients. Radiology. 2004;230:287-293.
13. Pankhurst QA, Connolly J, Jones SK, Dobson J. Applications of magnetic nanoparticles in biomedicine. J Phys D Appl Phys. 2003;36:R167-R181.
14. Vittorio O, Quaranta P, Raffa V. Magnetic carbon nanotubes: a new tool for shepherding mesenchymal stem cells by magnetic fields. Nanomedicine (Lond). 2011;6:43-54.
15. Wilhelm C, Bal L, Smirnov P, et al. Magnetic control of vascular network formation with magnetically labeled endothelial progenitor cells. Biomaterials. 2007;28:3797-3806.
16. De Silva MN, Almeida MV, Goldberg JL. Developing super-paramagnetic nanoparticles for central nervous system axon regeneration. In: Technical Proceedings of the 2007 NSTI Nanotechnology Conference and Trade Show,Volume 2. 2007 May 20-24; Santa Clara, CA.
17. Vergés MA, Costo R, Roca AG, et al. Uniform and water stable magnetite nanoparticles with diameters around the monodomain-multidomain limit. J Phys D Appl Phys. 2008;41:10.
18. Diaz G, Liu SS, Isola R, Diana A, Falchi AM. Mitochondrial localization of reactive oxygen species by dihydrofluorescein probes. Histochem Cell Biol. 2003;120:319-325.
19. Riemer J, Hoepken HH, Czerwinska H, Robinson SR, Dringen R. Colorimetric ferrozine-based assay for the quantitation of iron in cultured cells. Anal Biochem. 2004;331:370-375.
20. Kettering M, Winter J, Zeisberger M, et al. Magnetic nanoparticles as bimodal tools in magnetically induced labelling and magnetic heating of tumour cells: an in vitro study. Nanotechnology. 2007;18:175-101.
21. Raffa V, Vittorio O, Ciofani G, Pensabene V, Cuschieri A. Cell creeping and controlled migration by magnetic carbon nanotubes. Nanoscale Res Lett. 2009;5:257-262.
22. Emerit J, Beaumont C, Trivin F. Iron metabolism, free radicals, and oxidative injury. Biomed Pharmacother. 2001;55:333-339.
23. Babic M, Horák D, Trchová M, et al. Poly(L-lysine)-modified iron oxide nanoparticles for stem cell labeling. Bioconjug Chem. 2008;19:740-750.
24. Park EJ, Kim H, Kim Y, Yi J, Choi K, Park K. Inflammatory responses may be induced by a single intratracheal instillation of iron nanoparticles in mice. Toxicology. 2010;275(1-3):65-71.
25. Feng JH, Liu HL, Zhang LM, Bhakoo K, Lu LH. An insight into the metabolic responses of ultra-small superparamagnetic particles of iron oxide using metabonomic analysis of biofluids. Nanotechnology. 2010;21:395101.
26. Soenen SJ, Brisson AR, De Cuyper M. Addressing the problem of cationic lipid-mediated toxicity: The magnetoliposome model. Biomaterials. 2009;30:3691-3701.
27. Bergamini CM, Gambetti S, Dondi A, Cervellati C. Oxygen, reactive oxygen species and tissue damage. Curr Pharm Des. 2004;10:1611-1626.
28. Schwalbe M, Jorke C, Buske N, Hoffken K, Pachmann K, Clement JH. Selective reduction of the interaction of magnetic nanoparticles with leukocytes and tumor cells by human plasma. J Magn Magn Mater. 2005;293:433-437.
29. Soenen SJ, Nuytten N, De Meyer SF, De Smedt SC, De Cuyper M. High intracellular iron oxide nanoparticle concentrations affect cellular cytoskeleton and focal adhesion kinase-mediated signaling. Small. 2010;6:832-842.