Tandem attenuators control expression of the Salmonella mgtCBR virulence operon

Molecular Microbiology

Volumn 86, Issue 1, 2012, Pages 212-224

  Lee, Eun Jin ^a,b   Groisman, Eduardo A ^a  

^a HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^b YALE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; BACTERIAL PROTEIN; MESSENGER RNA; PROLINE; TRANSFER RNA;

AMINO ACID SUBSTITUTION; ARTICLE; BACTERIAL GENE; BACTERIAL VIRULENCE; CODON; CONTROLLED STUDY; GENE EXPRESSION; MGTB GENE; MGTC GENE; MGTP GENE; MGTR GENE; NONHUMAN; OPEN READING FRAME; OPERON; PRIORITY JOURNAL; SALMONELLA; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION;

5' UNTRANSLATED REGIONS; ADENOSINE TRIPHOSPHATASES; ADENOSINE TRIPHOSPHATE; BACTERIAL PROTEINS; CATION TRANSPORT PROTEINS; GENE EXPRESSION REGULATION, BACTERIAL; OPEN READING FRAMES; OPERON; PROTEIN BIOSYNTHESIS; RNA, TRANSFER, PRO; SALMONELLA TYPHIMURIUM; TRANSCRIPTION FACTORS; VIRULENCE; VIRULENCE FACTORS;

SALMONELLA; SALMONELLA ENTERICA SUBSP. ENTERICA SEROVAR TYPHIMURIUM;

EID: 84867076374     PISSN: 0950382X     EISSN: 13652958     Source Type: Journal    
DOI: 10.1111/j.1365-2958.2012.08188.x     Document Type: Article

References (43)

1. Alix, E., and Blanc-Potard, A.B. (2008) Peptide-assisted degradation of the Salmonella MgtC virulence factor. EMBO J 27: 546-557.
2. Bader, M.W., Sanowar, S., Daley, M.E., Schneider, A.R., Cho, U., Xu, W., etal. (2005) Recognition of antimicrobial peptides by a bacterial sensor kinase. Cell 122: 461-472.
3. Barchiesi, J., Castelli, M.E., Soncini, F.C., and Vescovi, E.G. (2008) mgtA Expression is induced by rob overexpression and mediates a Salmonella enterica resistance phenotype. J Bacteriol 190: 4951-4958.
4. Blanc-Potard, A.B., and Groisman, E.A. (1997) The Salmonella selC locus contains a pathogenicity island mediating intramacrophage survival. EMBO J 16: 5376-5385.
5. 2+ transporter in Salmonella enterica serovar Typhimurium. Biochem Biophys Res Commun 417: 318-323.
6. Cromie, M.J., Shi, Y., Latifi, T., and Groisman, E.A. (2006) An RNA sensor for intracellular Mg(2+). Cell 125: 71-84.
7. Csonka, L.N. (1988) Regulation of cytoplasmic proline levels in Salmonella typhimurium: effect of osmotic stress on synthesis, degradation, and cellular retention of proline. J Bacteriol 170: 2374-2378.
8. Csonka, L.N. (1989) Physiological and genetic responses of bacteria to osmotic stress. Microbiol Rev 53: 121-147.
9. Csonka, L.N., and Leisinger, T. (2007) Biosynthesis of proline. In Escherichia Coli and Salmonella: Cellular and Molecular Biology. Cohen, G. (ed.). Washington, DC: ASM, doi: 10.1128/ecosal 3.6.1.4.
10. Dann, C.E., 3rd, Wakeman, C.A., Sieling, C.L., Baker, S.C., Irnov, I., and Winkler, W.C. (2007) Structure and mechanism of a metal-sensing regulatory RNA. Cell 130: 878-892.
11. Datsenko, K.A., and Wanner, B.L. (2000) One-step inactivation of chromosomal genes in Escherichia coli K-12 using PCR products. Proc Natl Acad Sci USA 97: 6640-6645.
12. Davis, R.W., Bolstein, D., and Roth, J.R. (1980) Advanced Bacterial Genetics. Cold Spring Harbor: Cold Spring Harbor Lab.
13. Fields, P.I., Swanson, R.V., Haidaris, C.G., and Heffron, F. (1986) Mutants of Salmonella typhimurium that cannot survive within the macrophage are avirulent. Proc Natl Acad Sci USA 83: 5189-5193.
14. Fields, P.I., Groisman, E.A., and Heffron, F. (1989) A Salmonella locus that controls resistance to microbicidal proteins from phagocytic cells. Science 243: 1059-1062.
15. 2+ as an extracellular signal: environmental regulation of Salmonella virulence. Cell 84: 165-174.
16. Grundy, F.J., and Henkin, T.M. (2006) From ribosome to riboswitch: control of gene expression in bacteria by RNA structural rearrangements. Crit Rev Biochem Mol Biol 41: 329-338.
17. Henkin, T.M., and Yanofsky, C. (2002) Regulation by transcription attenuation in bacteria: how RNA provides instructions for transcription termination/antitermination decisions. Bioessays 24: 700-707.
18. Hollands, K., Proshkin, S., Sklyarova, S., Epshtein, V., Mironov, A., Nudler, E., and Groisman, E.A. (2012) Riboswitch control of Rho-dependent transcription termination. Proc Natl Acad Sci USA 109: 5376-5381.
19. Landick, R., Turnbough, C., and Yanofsky, C. (1996) Transcription attenuation. In Escherichia coli and Salmonella. Cellular and Molecular Biology. Neidhardt, F.C. (Editor in Chief), Curtiss, R., III, Ingraham, J.L., Lin, E.C.C., Low, K.B., Magasanik, B., etal. (eds). Washington, DC: ASM Press, pp. 1263-1286.
20. Lee, E.J., and Groisman, E.A. (2010) An antisense RNA that governs the expression kinetics of a multifunctional virulence gene. Mol Microbiol 76: 1020-1033.
21. Lee, E.J., and Groisman, E.A. (2012) Control of a Salmonella virulence locus by an ATP-sensing leader messenger RNA. Nature 486: 271-275.
22. 2+-responsive PhoP-PhoQ regulon in Salmonella enterica. J Bacteriol 185: 6287-6294.
23. McCaldon, P., and Argos, P. (1988) Oligopeptide biases in protein sequences and their use in predicting protein coding regions in nucleotide sequences. Proteins 4: 99-122.
24. Maguire, M.E. (2006) Magnesium transporters: properties, regulation and structure. Front Biosci 11: 3149-3163.
25. Merino, E., and Yanofsky, C. (2005) Transcription attenuation: a highly conserved regulatory strategy used by bacteria. Trends Genet 21: 260-264.
26. Miller, J.H. (1972) Experiments in Molecular Genetics. Cold Spring Harbor: Cold Spring Harbor Lab.
27. Naville, M., and Gautheret, D. (2009) Transcription attenuation in bacteria: theme and variations. Brief Funct Genomic Proteomic 8: 482-492.
28. Park, S.Y., Cromie, M.J., Lee, E.J., and Groisman, E.A. (2010) A bacterial mRNA leader that employs different mechanisms to sense disparate intracellular signals. Cell 142: 737-748.
29. Peters, J.M., Vangeloff, A.D., and Landick, R. (2011) Bacterial transcription terminators: the RNA 3′-end chronicles. J Mol Biol 412: 793-813.
30. Prost, L.R., Daley, M.E., Sage, V.L., Bader, M.W., Moual, H.L., Klevit, R.E., and Miller, S.I. (2007) Activation of the bacterial sensor kinase PhoQ by acidic pH. Mol Cell 26: 165-174.
31. Regulski, E.E., and Breaker, R.R. (2008) In-line probing analysis of riboswitches. Methods Mol Biol 419: 53-67.
32. Smith, R.L., and Maguire, M.E. (1998) Microbial magnesium transport: unusual transporters searching for identity. Mol Microbiol 28: 217-226.
33. 2+ transport locus of Salmonella typhimurium encodes a P-type ATPase. J Biol Chem 266: 815-823.
34. Soncini, F.C., Vescovi, E.G., and Groisman, E.A. (1995) Transcriptional autoregulation of the Salmonella typhimurium phoPQ operon. J Bacteriol 177: 4364-4371.
35. Soncini, F.C., Garcia Vescovi, E., Solomon, F., and Groisman, E.A. (1996) Molecular basis of the magnesium deprivation response in Salmonella typhimurium: identification of PhoP-regulated genes. J Bacteriol 178: 5092-5099.
36. Spinelli, S.V., Pontel, L.B., Garcia Vescovi, E., and Soncini, F.C. (2008) Regulation of magnesium homeostasis in Salmonella: Mg(2+) targets the mgtA transcript for degradation by RNase E. FEMS Microbiol Lett 280: 226-234.
37. Steitz, J.A. (1969) Polypeptide chain initiation: nucleotide sequences of the three ribosomal binding sites in bacteriophage R17 RNA. Nature 224: 957-964.
38. Sudarsan, N., Hammond, M.C., Block, K.F., Welz, R., Barrick, J.E., Roth, A., and Breaker, R.R. (2006) Tandem riboswitch architectures exhibit complex gene control functions. Science 314: 300-304.
39. Turnbough, C.L., Jr, and Switzer, R.L. (2008) Regulation of pyrimidine biosynthetic gene expression in bacteria: repression without repressors. Microbiol Mol Biol Rev 72: 266-300.
40. Valdivia, R.H., and Falkow, S. (1996) Bacterial genetics by flow cytometry: rapid isolation of Salmonella typhimurium acid-inducible promoters by differential fluorescence induction. Mol Microbiol 22: 367-378.
41. Yanofsky, C. (2004) The different roles of tryptophan transfer RNA in regulating trp operon expression in E. coli versus B. subtilis. Trends Genet 20: 367-374.
42. 2+ facilitates leader peptide translation to induce riboswitch-mediated transcription termination. EMBO J 30: 1485-1496.
43. Zwir, I., Latifi, T., Perez, J.C., Huang, H., and Groisman, E.A. (2012) The promoter architectural landscape of the Salmonella PhoP regulon. Mol Microbiol 84: 463-485.