Antidiabetic effect of plumbagin isolated from Plumbago zeylanica L. root and its effect on GLUT4 translocation in streptozotocin-induced diabetic rats

Food and Chemical Toxicology

Volumn 50, Issue 12, 2012, Pages 4356-4363

  Sunil, Christudas ^a   Duraipandiyan, Veeramuthu ^a,b   Agastian, Paul ^a   Ignacimuthu, Savarimuthu ^a  

^a LOYOLA COLLEGE   (India)

^b KING SAUD UNIVERSITY   (Saudi Arabia)

Author keywords

Diabetes mellitus; GLUT4; OGTT; Plumbagin; Plumbago zeylanica; Streptozotocin

Indexed keywords

ALANINE AMINOTRANSFERASE; ALKALINE PHOSPHATASE; ASPARTATE AMINOTRANSFERASE; CREATININE; FRUCTOSE BISPHOSPHATASE; GLIBENCLAMIDE; GLUCOSE; GLUCOSE 6 PHOSPHATASE; GLUCOSE TRANSPORTER 4; GLYCOGEN; HEXOKINASE; MESSENGER RNA; PLACEBO; PLASMA PROTEIN; PLUMBAGIN; PLUMBAGO ZEYLANICA EXTRACT; UREA;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ALKALINE PHOSPHATASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIDIABETIC ACTIVITY; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; BODY WEIGHT; CARBOHYDRATE METABOLISM; CONTROLLED STUDY; DRUG EFFECT; ENZYME ACTIVITY; ENZYME INHIBITION; EXPERIMENTAL DIABETES MELLITUS; GENE EXPRESSION; GLUCOSE BLOOD LEVEL; GLYCOGEN LIVER LEVEL; INSULIN BLOOD LEVEL; MALE; NONHUMAN; ORAL GLUCOSE TOLERANCE TEST; PLANT ROOT; PLUMBAGO ZEYLANICA; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RAT; SKELETAL MUSCLE; UREA BLOOD LEVEL;

ANIMALS; BLOOD GLUCOSE; BLOTTING, WESTERN; BODY WEIGHT; CREATININE; DIABETES MELLITUS, EXPERIMENTAL; FRUCTOSE-BISPHOSPHATASE; GENE EXPRESSION REGULATION; GLUCOSE TOLERANCE TEST; GLUCOSE TRANSPORTER TYPE 4; GLUCOSE-6-PHOSPHATASE; HEXOKINASE; HYPOGLYCEMIC AGENTS; INSULIN; LIVER GLYCOGEN; MALE; MUSCLE, SKELETAL; NAPHTHOQUINONES; PLANT EXTRACTS; PLANT ROOTS; PLUMBAGINACEAE; RATS; RATS, WISTAR; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TOXICITY TESTS, ACUTE;

PLUMBAGO ZEYLANICA; RATTUS;

EID: 84867044482     PISSN: 02786915     EISSN: 18736351     Source Type: Journal    
DOI: 10.1016/j.fct.2012.08.046     Document Type: Article

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