Mannich- and Lederer-Manasse-based analogues of the natural product S-(+)-curcuphenol as cancer proliferation and migration inhibitors

MedChemComm

Volumn 3, Issue 10, 2012, Pages 1309-1315

  Behery, Fathy A ^a   Sallam, Asmaa A ^a   El Sayed, Khalid A ^a  

^a UNIVERSITY OF LOUISIANA AT MONROE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 (HYDROXYMETHYL) 3 METHYL 6 (6 METHYLHEPT 5 EN 2 YL)PHENOL; 2 [(2 HYDROXYETHYLAMINO)METHYL] 3 METHYL 6 (6 METHYLHEPT 5 EN 2 YL)PHENOL; 2 [(3,3 DIETHOXYPROPYLAMINO)METHYL] 3 METHYL 6 (6 METHYLHEPT 5 EN 2 YL)PHENOL; 2 [(3,4 DIMETHOXYPHENETHYLAMINO)METHYL] 3 METHYL 6 (6 METHYLHEPT 5 EN 2 YL)PHENOL; 2 [(5 HYDROXYPENTYLAMINO)METHYL] 3 METHYL 6 (6 METHYLHEPT 5 EN 2 YL)PHENOL; 2 [5 METHYL 8 (6 METHYLHEPT 5 EN 2 YL) 2H BENZO[E][1,3]OXAZIN 3(4H) YL]ETHANOL; 3 (3,3 DIETHOXYPROPYL) 5 METHYL 8 (6 METHYLHEPT 5 EN 2 YL) 3,4 DIHYDRO 2H BENZO[E][1,3]OXAZINE; 3 (3,4 DIMETHOXYPHENETHYL) 5 METHYL 8 (6 METHYLHEPT 5 EN 2 YL) 3,4 DIHYDRO 2H BENZO[E][1,3]OXAZINE; 3 METHYL 6 (6 METHYLHEPT 5 EN 2 YL) 2 [(PIPERIDIN 4 YLMETHYLAMINO)METHYL]PHENOL; 3,4 DIHYDRO 2H 1,3 OXAZINE DERIVATIVE; 5 METHYL 8 (6 METHYLHEPT 5 EN 2 YL) 3 (PIPERIDIN 4 YLMETHYL) 3,4 DIHYDRO 2H BENZO[2][1,2]OXAZINE; 5 [2 HYDROXY 6 METHYL 3 (6 METHYLHEPT 5 EN 2 YL)BENZYLAMINO]PENTANOIC ACID; 5 [5 METHYL 8 (6 METHYLHEPT 5 EN 2 YL) 2H BENZO[E][1,3]OXAZIN 3(4H) YL]PENTANOIC ACID; 5 [5 METHYL 8 (6 METHYLHEPT 5 EN 2 YL) 2H BENZO[E][1,3]OXAZIN 3(H) YL]PENTAN 1 OL; ANTINEOPLASTIC AGENT; CURCUPHENOL DERIVATIVE; HYDROXYMETHYL DERIVATIVE; NATURAL PRODUCT; UNCLASSIFIED DRUG;

ANTIPROLIFERATIVE ACTIVITY; ARTICLE; BREAST CANCER; CANCER CELL; CANCER INHIBITION; CELL MIGRATION; CHEMICAL REACTION; CONTROLLED STUDY; DRUG POTENCY; FEMALE; HUMAN; HUMAN CELL; IC 50; LEDERER MANASSE REACTION; MALE; MANNICH REACTION; PRIORITY JOURNAL;

EID: 84867030989     PISSN: 20402503     EISSN: 20402511     Source Type: Journal    
DOI: 10.1039/c2md20185b     Document Type: Article

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