메뉴 건너뛰기




Volumn 98, Issue 4, 2012, Pages

Emerging nonanticoagulant role of low molecular weight heparins on extravillous trophoblast functions and on heparin binding-epidermal growth factor and cystein-rich angiogenic inducer 61 expression

Author keywords

AP 1; Cyr61; enoxaparin; Extravillous trophoblast invasiveness; HB EGF; low molecular weight heparins; MMP 2; tinzaparin

Indexed keywords

CYSTEIN RICH ANGIOGENIC INDUCER 61; ENOXAPARIN; GELATINASE A; HEPARIN BINDING EPIDERMAL GROWTH FACTOR; MEMBRANE PROTEIN; TINZAPARIN; TRANSCRIPTION FACTOR AP 1; UNCLASSIFIED DRUG;

EID: 84867023104     PISSN: 00150282     EISSN: 15565653     Source Type: Journal    
DOI: 10.1016/j.fertnstert.2012.06.042     Document Type: Article
Times cited : (24)

References (66)
  • 1
    • 20444369211 scopus 로고    scopus 로고
    • Heparin treatment in pregnancy loss: Potential therapeutic benefits beyond anticoagulation
    • G. Girardi Heparin treatment in pregnancy loss: potential therapeutic benefits beyond anticoagulation J Reprod Immunol 66 2005 45 51
    • (2005) J Reprod Immunol , vol.66 , pp. 45-51
    • Girardi, G.1
  • 2
    • 54449098367 scopus 로고    scopus 로고
    • The potential role of heparin in assisted conception
    • S.M. Nelson, and I.A. Greer The potential role of heparin in assisted conception Hum Reprod Update 14 2008 623 645
    • (2008) Hum Reprod Update , vol.14 , pp. 623-645
    • Nelson, S.M.1    Greer, I.A.2
  • 3
    • 15544381992 scopus 로고    scopus 로고
    • Unfractionated heparin, low molecular weight heparins, and pentasaccharide: Basic mechanism of actions, pharmacology, and clinical use
    • v
    • R.L. Bick, E.P. Frenkel, J. Walenga, J. Fareed, and D.A. Hoppensteadt Unfractionated heparin, low molecular weight heparins, and pentasaccharide: basic mechanism of actions, pharmacology, and clinical use Hematol Oncol Clin North Am 19 2005 1 51 v
    • (2005) Hematol Oncol Clin North Am , vol.19 , pp. 1-51
    • Bick, R.L.1    Frenkel, E.P.2    Walenga, J.3    Fareed, J.4    Hoppensteadt, D.A.5
  • 4
    • 0034100593 scopus 로고    scopus 로고
    • Gestational outcome in thrombophilic women with recurrent pregnancy loss treated by enoxaparin
    • B. Brenner, R. Hoffman, Z. Blumenfeld, Z. Weiner, and J.S. Younis Gestational outcome in thrombophilic women with recurrent pregnancy loss treated by enoxaparin Thromb Haemost 83 2000 693 697
    • (2000) Thromb Haemost , vol.83 , pp. 693-697
    • Brenner, B.1    Hoffman, R.2    Blumenfeld, Z.3    Weiner, Z.4    Younis, J.S.5
  • 5
    • 0141503825 scopus 로고    scopus 로고
    • Thromboprophylaxis improves the live birth rate in women with consecutive recurrent miscarriages and hereditary thrombophilia
    • H. Carp, M. Dolitzky, and A. Inbal Thromboprophylaxis improves the live birth rate in women with consecutive recurrent miscarriages and hereditary thrombophilia J Thromb Haemost 1 2003 433 438
    • (2003) J Thromb Haemost , vol.1 , pp. 433-438
    • Carp, H.1    Dolitzky, M.2    Inbal, A.3
  • 6
    • 79960639216 scopus 로고    scopus 로고
    • Antithrombotic treatment for recurrent pregnancy loss?
    • I.A. Greer Antithrombotic treatment for recurrent pregnancy loss? J Thromb Haemost 9 2011 302 305
    • (2011) J Thromb Haemost , vol.9 , pp. 302-305
    • Greer, I.A.1
  • 7
    • 0022366314 scopus 로고
    • Inhibition of mouse natural killer cytotoxicity by heparin
    • H. Yamamoto, S. Fuyama, S. Arai, and F. Sendo Inhibition of mouse natural killer cytotoxicity by heparin Cell Immunol 96 1985 409 417
    • (1985) Cell Immunol , vol.96 , pp. 409-417
    • Yamamoto, H.1    Fuyama, S.2    Arai, S.3    Sendo, F.4
  • 8
    • 0028885044 scopus 로고
    • Sulfated polysaccharide anticoagulants suppress natural killer cell activity in vitro
    • S. Johann, C. Zoller, S. Haas, G. Blumel, M. Lipp, and R. Foster Sulfated polysaccharide anticoagulants suppress natural killer cell activity in vitro Thromb Haemost 74 1995 998 1002
    • (1995) Thromb Haemost , vol.74 , pp. 998-1002
    • Johann, S.1    Zoller, C.2    Haas, S.3    Blumel, G.4    Lipp, M.5    Foster, R.6
  • 10
    • 0036126383 scopus 로고    scopus 로고
    • A novel attribute of enoxaparin: Inhibition of monocyte adhesion to endothelial cell adhesion molecules
    • I. Manduteanu, M. Voinea, M. Capraru, E. Dragomir, and M. Simionescu A novel attribute of enoxaparin: inhibition of monocyte adhesion to endothelial cell adhesion molecules Pharmacology 65 2002 32 37
    • (2002) Pharmacology , vol.65 , pp. 32-37
    • Manduteanu, I.1    Voinea, M.2    Capraru, M.3    Dragomir, E.4    Simionescu, M.5
  • 11
    • 0036734747 scopus 로고    scopus 로고
    • N-desulfated non-anticoagulant heparin inhibits leukocyte adhesion and transmigration in vitro and attenuates acute peritonitis and ischemia and reperfusion injury in vivo
    • J.G. Wan, J.S. Mu, H.S. Zhu, and J.G. Geng N-desulfated non-anticoagulant heparin inhibits leukocyte adhesion and transmigration in vitro and attenuates acute peritonitis and ischemia and reperfusion injury in vivo Inflamm Res 51 2002 435 443
    • (2002) Inflamm Res , vol.51 , pp. 435-443
    • Wan, J.G.1    Mu, J.S.2    Zhu, H.S.3    Geng, J.G.4
  • 12
    • 0034026312 scopus 로고    scopus 로고
    • The antagonism of interferon-gamma (IFN-gamma) by heparin: Examination of the blockade of class II MHC antigen and heat shock protein-70 expression
    • S.J. Fritchley, J.A. Kirby, and S. Ali The antagonism of interferon-gamma (IFN-gamma) by heparin: examination of the blockade of class II MHC antigen and heat shock protein-70 expression Clin Exp Immunol 120 2000 247 252
    • (2000) Clin Exp Immunol , vol.120 , pp. 247-252
    • Fritchley, S.J.1    Kirby, J.A.2    Ali, S.3
  • 13
    • 9144243607 scopus 로고    scopus 로고
    • Heparin prevents antiphospholipid antibody-induced fetal loss by inhibiting complement activation
    • G. Girardi, P. Redecha, and J.E. Salmon Heparin prevents antiphospholipid antibody-induced fetal loss by inhibiting complement activation Nat Med 10 2004 1222 1226
    • (2004) Nat Med , vol.10 , pp. 1222-1226
    • Girardi, G.1    Redecha, P.2    Salmon, J.E.3
  • 14
    • 0026781082 scopus 로고
    • Control of angiogenesis by heparin and other sulfated polysaccharides
    • J. Folkman, and Y. Shing Control of angiogenesis by heparin and other sulfated polysaccharides Adv Exp Med 313 1992 355 364
    • (1992) Adv Exp Med , vol.313 , pp. 355-364
    • Folkman, J.1    Shing, Y.2
  • 15
    • 0032764724 scopus 로고    scopus 로고
    • Association of heparin with basic fibroblast growth factor, epidermal gorwth factor and constitutive nitric oxyde synthase on healing of gastric ulcer in rats
    • Y. Li, H.Y. Wang, and C.H. Cho Association of heparin with basic fibroblast growth factor, epidermal gorwth factor and constitutive nitric oxyde synthase on healing of gastric ulcer in rats J Pharmacol Exp Ther 290 1999 789 796
    • (1999) J Pharmacol Exp Ther , vol.290 , pp. 789-796
    • Li, Y.1    Wang, H.Y.2    Cho, C.H.3
  • 17
    • 84155165096 scopus 로고    scopus 로고
    • Low-molecular-weight heparins induce decidual heparin-binding epidermal growth factor-like growth factor expression and promote survival of decidual cells undergoing apoptosis
    • N. Di Simone, F. Di Nicuolo, R. Castellani, M. Veglia, C. Tersigni, and M. Silano Low-molecular-weight heparins induce decidual heparin-binding epidermal growth factor-like growth factor expression and promote survival of decidual cells undergoing apoptosis Fertil Steril 97 2012 169 177.e1
    • (2012) Fertil Steril , vol.97
    • Di Simone, N.1    Di Nicuolo, F.2    Castellani, R.3    Veglia, M.4    Tersigni, C.5    Silano, M.6
  • 18
    • 77951744440 scopus 로고    scopus 로고
    • Decreased expression of heparin-binding epidermal growth factor-like growth factor as a newly identified pathogenic mechanism of antiphospholipid- mediated defective placentation
    • N. Di Simone, R. Marana, R. Castellani, F. Di Nicuolo, M.C. D'Alessio, and E. Raschi Decreased expression of heparin-binding epidermal growth factor-like growth factor as a newly identified pathogenic mechanism of antiphospholipid-mediated defective placentation Arthritis Rheum 62 2010 1504 1512
    • (2010) Arthritis Rheum , vol.62 , pp. 1504-1512
    • Di Simone, N.1    Marana, R.2    Castellani, R.3    Di Nicuolo, F.4    D'Alessio, M.C.5    Raschi, E.6
  • 19
    • 33947725054 scopus 로고    scopus 로고
    • Low-molecular weight heparin induces in vitro trophoblast invasiveness: Role of matrix metalloproteinases and tissue inhibitors
    • N. Di Simone, F. Di Nicuolo, M. Sanguinetti, S. Ferrazzani, M.C. D'Alessio, and R. Castellani Low-molecular weight heparin induces in vitro trophoblast invasiveness: role of matrix metalloproteinases and tissue inhibitors Placenta 28 2007 298 304
    • (2007) Placenta , vol.28 , pp. 298-304
    • Di Simone, N.1    Di Nicuolo, F.2    Sanguinetti, M.3    Ferrazzani, S.4    D'Alessio, M.C.5    Castellani, R.6
  • 20
    • 84862591271 scopus 로고    scopus 로고
    • Vessel remodelling, pregnancy hormones and extravillous trophoblast function
    • J.Z. Chen, P.M. Sheehan, S.P. Brennecke, and R.J. Keogh Vessel remodelling, pregnancy hormones and extravillous trophoblast function Mol Cell Endocrinol 349 2012 138 144
    • (2012) Mol Cell Endocrinol , vol.349 , pp. 138-144
    • Chen, J.Z.1    Sheehan, P.M.2    Brennecke, S.P.3    Keogh, R.J.4
  • 21
    • 33745195720 scopus 로고    scopus 로고
    • Metalloproteinases and human placental invasiveness
    • M. Cohen, A. Meisser, and P. Bischof Metalloproteinases and human placental invasiveness Placenta 27 2006 783 793
    • (2006) Placenta , vol.27 , pp. 783-793
    • Cohen, M.1    Meisser, A.2    Bischof, P.3
  • 22
    • 33847290472 scopus 로고    scopus 로고
    • Molecular circuits shared by placental and cancer cells, and their implications in the proliferative, invasive and migratory capacities of trophoblasts
    • C. Ferretti, L. Bruni, V. Dangles-Marie, A.P. Pecking, and D. Bellet Molecular circuits shared by placental and cancer cells, and their implications in the proliferative, invasive and migratory capacities of trophoblasts Hum Reprod Update 13 2007 121 141
    • (2007) Hum Reprod Update , vol.13 , pp. 121-141
    • Ferretti, C.1    Bruni, L.2    Dangles-Marie, V.3    Pecking, A.P.4    Bellet, D.5
  • 23
  • 24
    • 0030058026 scopus 로고    scopus 로고
    • Mouse preimplantation blastocysts adhere to cells expressing the transmembrane form of heparin-binding EGF-like growth factor
    • G. Raab, K. Kover, B.C. Paria, S.K. Dey, R.M. Ezzell, and M. Klagsbrun Mouse preimplantation blastocysts adhere to cells expressing the transmembrane form of heparin-binding EGF-like growth factor Development 122 1996 637 645
    • (1996) Development , vol.122 , pp. 637-645
    • Raab, G.1    Kover, K.2    Paria, B.C.3    Dey, S.K.4    Ezzell, R.M.5    Klagsbrun, M.6
  • 25
    • 0028324021 scopus 로고
    • T lymphocytes synthesize and export heparin-binding epidermal growth factor-like growth factor and basic fibroblast growth factor, mitogens for vascular cells and fibroblasts: Differential production and release by CD4- and CD8- T cells
    • S. Blotnick, G.E. Peoples, M.R. Freeman, T.J. Eberlein, and M. Klagsbrun T lymphocytes synthesize and export heparin-binding epidermal growth factor-like growth factor and basic fibroblast growth factor, mitogens for vascular cells and fibroblasts: differential production and release by CD4- and CD8- T cells Proc Natl Acad Sci U S A 91 1994 2890 2894
    • (1994) Proc Natl Acad Sci U S A , vol.91 , pp. 2890-2894
    • Blotnick, S.1    Peoples, G.E.2    Freeman, M.R.3    Eberlein, T.J.4    Klagsbrun, M.5
  • 26
    • 0029965446 scopus 로고    scopus 로고
    • Cyr61, a product of a growth inducible immediate early gene, promotes cell proliferation, migration and adhesion
    • M.L. Kireeva, F.E. Mo, G.P. Yang, and L.F. Lau Cyr61, a product of a growth inducible immediate early gene, promotes cell proliferation, migration and adhesion Mol Cell 16 1996 1326 1334
    • (1996) Mol Cell , vol.16 , pp. 1326-1334
    • Kireeva, M.L.1    Mo, F.E.2    Yang, G.P.3    Lau, L.F.4
  • 27
    • 0032568608 scopus 로고    scopus 로고
    • CYR61, a product of a growth factor-inducible immediate early gene, promotes angiogenesis and tumor growth
    • A.M. Babic, M.L. Kireeva, T.V. Kolesnikova, and L.F. Lau CYR61, a product of a growth factor-inducible immediate early gene, promotes angiogenesis and tumor growth Proc Natl Acad Sci 95 1998 6355 6360
    • (1998) Proc Natl Acad Sci , vol.95 , pp. 6355-6360
    • Babic, A.M.1    Kireeva, M.L.2    Kolesnikova, T.V.3    Lau, L.F.4
  • 29
    • 84857785456 scopus 로고    scopus 로고
    • Effect of low molecular weight heparin and heparin-binding epidermal growth factor on human trophoblast in first trimester
    • Y. Chen, W. Xiao-Xia, J. Tan, M. Liu, Y. Liu, and J. Zhang Effect of low molecular weight heparin and heparin-binding epidermal growth factor on human trophoblast in first trimester Fertil Steril 97 2012 764 770
    • (2012) Fertil Steril , vol.97 , pp. 764-770
    • Chen, Y.1    Xiao-Xia, W.2    Tan, J.3    Liu, M.4    Liu, Y.5    Zhang, J.6
  • 30
    • 77954516498 scopus 로고    scopus 로고
    • Regulation of the matricellular proteins CYR61 (CCN1) and NOV (CCN3) by hypoxia-inducible factor-1α and transforming-growth factor-β3 in the human trophoblast
    • N. Wolf, W. Yang, C.E. Dunk, I. Gashaw, S.J. Lye, and T. Ring Regulation of the matricellular proteins CYR61 (CCN1) and NOV (CCN3) by hypoxia-inducible factor-1α and transforming-growth factor-β3 in the human trophoblast Endocrinology 151 2010 2835 2845
    • (2010) Endocrinology , vol.151 , pp. 2835-2845
    • Wolf, N.1    Yang, W.2    Dunk, C.E.3    Gashaw, I.4    Lye, S.J.5    Ring, T.6
  • 31
    • 0032829051 scopus 로고    scopus 로고
    • AP-1 mediates stretch-induced expression of HB-EGF in bladder smooth muscle cells
    • J.M. Park, R.M. Adam, C.A. Peters, P.D. Guthrie, Z. Sun, and M. Klagsbrun AP-1 mediates stretch-induced expression of HB-EGF in bladder smooth muscle cells Am J Physiol 277 1999 294 301
    • (1999) Am J Physiol , vol.277 , pp. 294-301
    • Park, J.M.1    Adam, R.M.2    Peters, C.A.3    Guthrie, P.D.4    Sun, Z.5    Klagsbrun, M.6
  • 32
    • 0035229188 scopus 로고    scopus 로고
    • Oxidant stress activated AP-1 and heparin-binding epidermal growth factor-like growth factor transcription in renal epithelial cells
    • M. Sakai, T. Tsukada, and R.C. Harris Oxidant stress activated AP-1 and heparin-binding epidermal growth factor-like growth factor transcription in renal epithelial cells Exp Nephrol 9 2001 28 39
    • (2001) Exp Nephrol , vol.9 , pp. 28-39
    • Sakai, M.1    Tsukada, T.2    Harris, R.C.3
  • 33
    • 78649484217 scopus 로고    scopus 로고
    • Regulation of Cyr61/CCN1 expression by hypoxia through cooperation of c-Jun/AP-1 and HIF-1α in retinal vascular endothelial cells
    • J.J. You, C.M. Yang, M.S. Chen, and C.H. Yang Regulation of Cyr61/CCN1 expression by hypoxia through cooperation of c-Jun/AP-1 and HIF-1α in retinal vascular endothelial cells Exp Eye Res 91 2010 825 836
    • (2010) Exp Eye Res , vol.91 , pp. 825-836
    • You, J.J.1    Yang, C.M.2    Chen, M.S.3    Yang, C.H.4
  • 34
    • 60149091505 scopus 로고    scopus 로고
    • Cyr61 increases migration and MMP-13 expression via αvβ3 integrin, FAK, ERK and AP-1 dependent pathway in human chondrosarcoma cells
    • T.W. Tan, W.H. Yang, Y.T. Lin, S.F. Hsu, T.M. Li, and S.T. Kao Cyr61 increases migration and MMP-13 expression via αvβ3 integrin, FAK, ERK and AP-1 dependent pathway in human chondrosarcoma cells Carcinogenesis 30 2009 258 268
    • (2009) Carcinogenesis , vol.30 , pp. 258-268
    • Tan, T.W.1    Yang, W.H.2    Lin, Y.T.3    Hsu, S.F.4    Li, T.M.5    Kao, S.T.6
  • 36
    • 0029955027 scopus 로고    scopus 로고
    • Trophoblast migration during human placental implantation
    • T.D. Burrows, A. King, and Y.W. Lokr Trophoblast migration during human placental implantation Hum Reprod Update 2 1996 307 321
    • (1996) Hum Reprod Update , vol.2 , pp. 307-321
    • Burrows, T.D.1    King, A.2    Lokr, Y.W.3
  • 37
    • 71649090820 scopus 로고    scopus 로고
    • Ets-2 and p53 mediate cAMP-induced MMP-2 expression, activity and trophoblast invasion
    • E. Staun-Ram, S. Goldman, and E. Shalev Ets-2 and p53 mediate cAMP-induced MMP-2 expression, activity and trophoblast invasion Reprod Biol Endocrinol 7 2009 135
    • (2009) Reprod Biol Endocrinol , vol.7 , pp. 135
    • Staun-Ram, E.1    Goldman, S.2    Shalev, E.3
  • 38
    • 0042416783 scopus 로고    scopus 로고
    • Expression and activity of matrix metalloproteinase 2 and 9 in human trophoblasts
    • K. Isaka, S. Usuda, H. Ito, Y. Sagawa, H. Nakamura, and H. Nishi Expression and activity of matrix metalloproteinase 2 and 9 in human trophoblasts Placenta 24 2003 53 64
    • (2003) Placenta , vol.24 , pp. 53-64
    • Isaka, K.1    Usuda, S.2    Ito, H.3    Sagawa, Y.4    Nakamura, H.5    Nishi, H.6
  • 39
    • 0033830725 scopus 로고    scopus 로고
    • Heparin-binding EGF-like growth factor: A juxtacrine growth factor
    • R. Iwamoto, and E. Mekada Heparin-binding EGF-like growth factor: a juxtacrine growth factor Cytokine Growth Factor Rev 11 2000 335 344
    • (2000) Cytokine Growth Factor Rev , vol.11 , pp. 335-344
    • Iwamoto, R.1    Mekada, E.2
  • 40
    • 14044270220 scopus 로고    scopus 로고
    • Heparin-binding epidermal growth factor and its receptors mediate decidualization and potentiate survival of human endometrial stromal cells
    • K. Chobotova, N. Karpovich, J. Carver, S. Manek, W.J. Gullick, and D.H. Barlow Heparin-binding epidermal growth factor and its receptors mediate decidualization and potentiate survival of human endometrial stromal cells J Clin Endocrinol Metab 90 2005 913 919
    • (2005) J Clin Endocrinol Metab , vol.90 , pp. 913-919
    • Chobotova, K.1    Karpovich, N.2    Carver, J.3    Manek, S.4    Gullick, W.J.5    Barlow, D.H.6
  • 41
    • 0345869896 scopus 로고    scopus 로고
    • Heparin-binding EGF-like growth factor regulates human extravillous cytotrophoblast development during conversion to the invasive phenotype
    • R.E. Leach, B. Kilburn, J. Wang, Z. Liu, R. Romero, and D.R. Armant Heparin-binding EGF-like growth factor regulates human extravillous cytotrophoblast development during conversion to the invasive phenotype Dev Biol 266 2004 223 237
    • (2004) Dev Biol , vol.266 , pp. 223-237
    • Leach, R.E.1    Kilburn, B.2    Wang, J.3    Liu, Z.4    Romero, R.5    Armant, D.R.6
  • 42
    • 0035970052 scopus 로고    scopus 로고
    • Cellular and molecular responses of the uterus to embryo implantation can be elicited by locally applied growth factors
    • B.C. Paria, W. Ma, J. Tan, S. Raja, S.K. Das, and S.K. Dey Cellular and molecular responses of the uterus to embryo implantation can be elicited by locally applied growth factors Proc Natl Acad Sci U S A 98 2001 1047 1052
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 1047-1052
    • Paria, B.C.1    Ma, W.2    Tan, J.3    Raja, S.4    Das, S.K.5    Dey, S.K.6
  • 43
  • 44
    • 79952310759 scopus 로고    scopus 로고
    • The "great obstetrical syndromes" are associated with disorders of deep placentation
    • I. Brosens, R. Pijnenborg, L. Vercruysse, and R. Romero The "great obstetrical syndromes" are associated with disorders of deep placentation Am J Obstet Gynecol 204 2011 193 201
    • (2011) Am J Obstet Gynecol , vol.204 , pp. 193-201
    • Brosens, I.1    Pijnenborg, R.2    Vercruysse, L.3    Romero, R.4
  • 45
    • 0032983892 scopus 로고    scopus 로고
    • Preeclampsia is associated with widespread apoptosis of placental cytotrophoblasts within the uterine wall
    • E. Di Federico, O. Genbacev, and S.J. Fisher Preeclampsia is associated with widespread apoptosis of placental cytotrophoblasts within the uterine wall Am J Pathol 155 1999 293 301
    • (1999) Am J Pathol , vol.155 , pp. 293-301
    • Di Federico, E.1    Genbacev, O.2    Fisher, S.J.3
  • 47
    • 80052925829 scopus 로고    scopus 로고
    • CCN/Cyr61: The very model of a modern matricellular protein
    • L.F. Lau CCN/Cyr61: the very model of a modern matricellular protein Cell Mol Life Sci 68 2011 3149 3163
    • (2011) Cell Mol Life Sci , vol.68 , pp. 3149-3163
    • Lau, L.F.1
  • 48
    • 84872427635 scopus 로고    scopus 로고
    • Adhesion of human umbilical vein endothelial cells to the immediate-early gene product Cyr61 is mediated through integrin αvβ2
    • M.L. Kireeva, S.C.T. Lam, and L.F. Lau Adhesion of human umbilical vein endothelial cells to the immediate-early gene product Cyr61 is mediated through integrin αvβ2 J Biol Chem 276 1998 351 357
    • (1998) J Biol Chem , vol.276 , pp. 351-357
    • Kireeva, M.L.1    Lam, S.C.T.2    Lau, L.F.3
  • 49
    • 0026182979 scopus 로고
    • Cyr61, product of a growth factor-inducible immediate early gene, is associated with the extracellular matrix and the cell surface
    • G.P. Yang, and L.F. Lau Cyr61, product of a growth factor-inducible immediate early gene, is associated with the extracellular matrix and the cell surface Cell Growth Differ 2 1991 351 357
    • (1991) Cell Growth Differ , vol.2 , pp. 351-357
    • Yang, G.P.1    Lau, L.F.2
  • 51
    • 77951959540 scopus 로고    scopus 로고
    • MicroRNA-155 contributes to preeclampsia by down-regulating CYR61
    • Y. Zhang, Z. Diao, L. Su, H. Sun, R. Li, and H. Cui MicroRNA-155 contributes to preeclampsia by down-regulating CYR61 Am J Obstet Gynecol 202 2010 466 467
    • (2010) Am J Obstet Gynecol , vol.202 , pp. 466-467
    • Zhang, Y.1    Diao, Z.2    Su, L.3    Sun, H.4    Li, R.5    Cui, H.6
  • 52
    • 33745589760 scopus 로고    scopus 로고
    • Decreased expression of the angiogenic regulators CYR61 (CCN1) and NOV (CCN3) in human placenta is associated with pre-eclampsia
    • A. Gellhaus, M. Schmidt, C. Dunk, S.J. Lye, R. Kimmig, and E. Winterhager Decreased expression of the angiogenic regulators CYR61 (CCN1) and NOV (CCN3) in human placenta is associated with pre-eclampsia Mol Hum Reprod 12 2006 389 399
    • (2006) Mol Hum Reprod , vol.12 , pp. 389-399
    • Gellhaus, A.1    Schmidt, M.2    Dunk, C.3    Lye, S.J.4    Kimmig, R.5    Winterhager, E.6
  • 53
    • 38749086173 scopus 로고    scopus 로고
    • The circulating proangiogenic factos CYR61 (CCN1) and NOV (CCN3) are significantly decreased in placentae and sera of preeclamptic patients
    • A. Gellhaus, M. Schmidt, C. Dunk, S.J. Lye, and E. Winterhager The circulating proangiogenic factos CYR61 (CCN1) and NOV (CCN3) are significantly decreased in placentae and sera of preeclamptic patients Reprod Sci 14 2007 46 52
    • (2007) Reprod Sci , vol.14 , pp. 46-52
    • Gellhaus, A.1    Schmidt, M.2    Dunk, C.3    Lye, S.J.4    Winterhager, E.5
  • 54
    • 77952421301 scopus 로고    scopus 로고
    • Ultraviolet irradiation induces CYR61/CCN1, a mediator of collagen homeostasis, through activation of transcription factor AP-1 in human skin fibroblasts
    • T. Quan, Z. Qin, Y. Xu, T. He, S. Kang, and J.J. Voorhees Ultraviolet irradiation induces CYR61/CCN1, a mediator of collagen homeostasis, through activation of transcription factor AP-1 in human skin fibroblasts J Invest Dermatol 130 2010 1690 1706
    • (2010) J Invest Dermatol , vol.130 , pp. 1690-1706
    • Quan, T.1    Qin, Z.2    Xu, Y.3    He, T.4    Kang, S.5    Voorhees, J.J.6
  • 55
    • 12844250084 scopus 로고    scopus 로고
    • Heparin and aspirin attenuate placental apoptosis in vitro: Implications for early pregnancy failure
    • P. Bose, S. Black, M. Kadyrov, U. Weissenborn, J. Neulen, and L. Regan Heparin and aspirin attenuate placental apoptosis in vitro: implications for early pregnancy failure Am J Obstet Gynecol 192 2005 23 30
    • (2005) Am J Obstet Gynecol , vol.192 , pp. 23-30
    • Bose, P.1    Black, S.2    Kadyrov, M.3    Weissenborn, U.4    Neulen, J.5    Regan, L.6
  • 56
    • 34250879580 scopus 로고    scopus 로고
    • Epidermal growth factor-like growth factors prevent apoptosis of alcohol-exposed human placental cytotrophoblast cells
    • G.S. Wolff, P.J. Chiang, S.M. Smith, R. Romero, and D.R. Armant Epidermal growth factor-like growth factors prevent apoptosis of alcohol-exposed human placental cytotrophoblast cells Biol Reprod 77 2007 53 60
    • (2007) Biol Reprod , vol.77 , pp. 53-60
    • Wolff, G.S.1    Chiang, P.J.2    Smith, S.M.3    Romero, R.4    Armant, D.R.5
  • 58
    • 0035380706 scopus 로고    scopus 로고
    • Differentiation of the low molecular weight heparins
    • E. Recine Differentiation of the low molecular weight heparins Pharmacotherapy 21 2001 71S 72S
    • (2001) Pharmacotherapy , vol.21
    • Recine, E.1
  • 59
    • 27144534062 scopus 로고    scopus 로고
    • A comparison of the effects of unfractionated heparin, dalteparin and dapanaroid on vascular endothelial growth factor-induced tumour angiogenesis and heparanase activity
    • H. Takahashi, S. Ebihara, T. Okazaki, M. Asada, H. Sasaki, and M. Yamaya A comparison of the effects of unfractionated heparin, dalteparin and dapanaroid on vascular endothelial growth factor-induced tumour angiogenesis and heparanase activity Br J Pharmacol 146 2005 333 343
    • (2005) Br J Pharmacol , vol.146 , pp. 333-343
    • Takahashi, H.1    Ebihara, S.2    Okazaki, T.3    Asada, M.4    Sasaki, H.5    Yamaya, M.6
  • 60
    • 0029934389 scopus 로고    scopus 로고
    • Antiphospholipid antibody-associated recurrent pregnancy loss: Treatment with heparin and low-dose aspirin is superior to low-dose aspirin alone
    • W.H. Kutteh Antiphospholipid antibody-associated recurrent pregnancy loss: treatment with heparin and low-dose aspirin is superior to low-dose aspirin alone Am J Obstet Gynecol 174 1996 1584 1589
    • (1996) Am J Obstet Gynecol , vol.174 , pp. 1584-1589
    • Kutteh, W.H.1
  • 61
    • 0031022366 scopus 로고    scopus 로고
    • Randomised controlled trial of aspirin and aspirin plus heparin in pregnant women with recurrent miscarriage associated with phospholipid antibodies (or antiphospholipid antibodies)
    • R. Rai, H. Cohen, M. Dave, and L. Regan Randomised controlled trial of aspirin and aspirin plus heparin in pregnant women with recurrent miscarriage associated with phospholipid antibodies (or antiphospholipid antibodies) Br Med J 314 1997 253 257
    • (1997) Br Med J , vol.314 , pp. 253-257
    • Rai, R.1    Cohen, H.2    Dave, M.3    Regan, L.4
  • 62
    • 45749103279 scopus 로고    scopus 로고
    • Low-molecular weight heparin in patients with recurrent early miscarriages of unknown aetiology
    • A.M. Badawy, M. Khiary, L.S. Sherif, M. Hassan, A. Ragab, and I. Abdelall Low-molecular weight heparin in patients with recurrent early miscarriages of unknown aetiology J Obstet Gynaecol 28 2008 280 284
    • (2008) J Obstet Gynaecol , vol.28 , pp. 280-284
    • Badawy, A.M.1    Khiary, M.2    Sherif, L.S.3    Hassan, M.4    Ragab, A.5    Abdelall, I.6
  • 63
    • 69149098103 scopus 로고    scopus 로고
    • Luteal phase empirical low molecular weight heparin administration in patients with failed ICSI embryo transfer cycles: A randomized open-labeled pilot trial
    • B. Urman, B. Ata, K. Yakin, C. Alatas, S. Aksoy, and R. Mercan Luteal phase empirical low molecular weight heparin administration in patients with failed ICSI embryo transfer cycles: a randomized open-labeled pilot trial Hum Reprod 24 2009 1640 1647
    • (2009) Hum Reprod , vol.24 , pp. 1640-1647
    • Urman, B.1    Ata, B.2    Yakin, K.3    Alatas, C.4    Aksoy, S.5    Mercan, R.6
  • 64
    • 77951714717 scopus 로고    scopus 로고
    • SPIN (Scottish Pregnancy Intervention) study: A multicenter, randomized controlled trial of low-molecular-weight heparin and low-dose aspirin in women with recurrent miscarriage
    • P. Clark, I.D. Walker, P. Langhorne, L. Crichton, A. Thomson, and M. Greaves SPIN (Scottish Pregnancy Intervention) study: a multicenter, randomized controlled trial of low-molecular-weight heparin and low-dose aspirin in women with recurrent miscarriage Blood 115 2010 4162 4167
    • (2010) Blood , vol.115 , pp. 4162-4167
    • Clark, P.1    Walker, I.D.2    Langhorne, P.3    Crichton, L.4    Thomson, A.5    Greaves, M.6
  • 66
    • 77951708308 scopus 로고    scopus 로고
    • Antithrombotic therapy for recurrent miscarriage?
    • I.A. Greer Antithrombotic therapy for recurrent miscarriage? N Engl J Med 362 2010 1630 1631
    • (2010) N Engl J Med , vol.362 , pp. 1630-1631
    • Greer, I.A.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.