Reversibility of intrathoracic lipotoxicity in obesity after bariatric surgery: Use of magnetic resonance imaging

Journal of the American College of Cardiology

Volumn 60, Issue 15, 2012, Pages 1390-1392

  De Roos, Albert ^a  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

epicardial fat; magnetic resonance spectroscopy; myocardial fat; myocardial triglyceride content; visceral abdominal fat

Indexed keywords

TRIACYLGLYCEROL;

ARTERIAL STIFFNESS; BARIATRIC SURGERY; BODY FAT; BODY MASS; DIASTOLIC BLOOD PRESSURE; DISEASE ASSOCIATION; GLYCEMIC CONTROL; HEART DILATATION; HEART FUNCTION; HEART LEFT VENTRICLE MASS; HEART OUTPUT; HEART VOLUME; HUMAN; INTRAABDOMINAL FAT; INTRATHORACIC LIPOTOXICITY; LIPOTOXICITY; METABOLIC SYNDROME X; MYOCARDIAL TRIGLYCERIDE CONTENT; NOTE; NUCLEAR MAGNETIC RESONANCE IMAGING; OBESITY; PARAMETERS; PERICARDIAL FAT; PRIORITY JOURNAL; PULSE WAVE; SLEEP DISORDERED BREATHING; SUBCUTANEOUS FAT; WEIGHT REDUCTION;

EID: 84866981865     PISSN: 07351097     EISSN: 15583597     Source Type: Journal    
DOI: 10.1016/j.jacc.2012.07.010     Document Type: Editorial

References (25)

1. P. Iozzo Myocardial, perivascular, and epicardial fat Diabetes Care 34 Suppl 2 2011 S371 S379
2. B. Gaborit, F. Kober, A. Jacquier Epicardial fat volume is associated with coronary microvascular response in healthy subjects: a pilot study Obesity 20 2012 1200 1205
3. M. Snel, J.T. Jonker, J. Schoones Ectopic fat and insulin resistance: pathophysiology and effect of diet and lifestyle interventions Int J Endocrinol 2012 2012 983814
4. D.A. Hickson, J. Liu, A. Bidulescu Pericardial fat is associated with impaired lung function and a restrictive lung pattern in adults The Jackson Heart Study Chest 140 2011 1567 1573
5. R. Stienstra, C.J. Tack, T.D. Kanneganti, L.A. Joosten, M.G. Netea The inflammasome puts obesity in the danger zone Cell Metab 15 2012 10 18
6. A. de Roos Science to practice: why follow the track of macrophages in obesity? Radiology 263 2012 623 625
7. Z.H. Huang, D.J. Espiritu, A. Uy Adipose tissue depot-specific differences in adipocyte apolipoprotein E expression Metabolism Clin Exp 60 2011 1692 1701
8. J.T. Jonker, H.J. Lamb, R.W. van der Meer Pioglitazone compared with metformin increases pericardial fat volume in patients with type 2 diabetes mellitus J Clin Endocrinol Metab 95 2010 456 460
9. G. Iacobellis, A. Bianco Epicardial adipose tissue: emerging physiological, pathophysiological and clinical features Trends Endocrinol Metab 22 2011 450 457
10. A. Chokshi, K. Drosatos, F.H. Cheema Ventricular assist device implantation corrects myocardial lipotoxicity, reverses insulin resistance, and normalizes cardiac metabolism in patients with advanced heart failure Circulation 125 2012 2844 2853
11. S. Hammer, M. Snel, H.J. Lamb Prolonged caloric restriction in obese patients with type 2 diabetes mellitus decreases myocardial triglyceride content and improves myocardial function J Am Coll Cardiol 52 2008 1006 1012
12. J.M. McGavock, R.G. Victor, R.H. Unger, L.S. Szczepaniak Adiposity of the heart, revisited Ann Intern Med 144 2006 517 524
13. L.S. Szczepaniak, R.G. Victor, L. Orci, R.H. Unger Forgotten but not gone: the rediscovery of fatty heart, the most common unrecognized disease in America Circ Res 101 2007 759 767
14. J.A. Den Hollander, W.T. Evanaochko, G.M. Pohost Observation of cardiac lipids in humans by localized 1H magnetic resonance spectroscopic imaging Magn Reson Med 32 1994 175 180
15. L.S. Szczepaniak, R.L. Dobbins, G.J. Metzger Myocardial triglycerides and systolic function in humans: in vivo evaluation by localized proton spectroscopy and cardiac imaging Magn Reson Med 49 2003 417 423
16. I. Zib, A.N. Jacob, I. Lingvay Effect of pioglitazone therapy on myocardial and hepatic steatosis in insulin-treated patients with type 2 diabetes J Invest Med 55 2007 230 236
17. B. Gaborit, A. Jacquier, F. Kober Effects of bariatric surgery on cardiac ectopic fat: lesser decrease in epicardial fat compared to visceral fat loss and no change in myocardial triglyceride content J Am Coll Cardiol 60 2012 1381 1389
18. M. Snel, J.T. Jonker, S. Hammer Long-term beneficial effect of a 16-week very low calorie diet on pericardial fat in obese type 2 diabetes mellitus patients Obesity (Silver Spring) 20 2012 1572 1576
19. R.W. Van der Meer, H.J. Lamb, J.W.A. Smit, A. de Roos MR imaging evaluation of cardiovascular risk in metabolic syndrome Radiology 264 2012 21 37
20. S.G.C. Van Elderen, A. Brandts, J.J.M. Westenberg Aortic stiffness is associated with cardiac function and cerebral small vessel disease in patients with type 1 diabetes mellitus: assessment by MR imaging Eur Radiol 20 2010 1132 1138
21. S.G.C. Van Elderen, J.J.M. Westenberg, A. Brandts Increased aortic stiffness measured by MR imaging in type 1 diabetes mellitus patients and the relationship with renal function Am J Roentgenol 196 2011 697 701
22. S.G.C. Van Elderen, A. Brandts, J. Van der Grond Cerebral perfusion and aortic stiffness are independent predictors of white matter brain atrophy in type 1 diabetes mellitus patients: assessment by MR imaging Diabetes Care 34 2011 459 463
23. S.G.C. Van Elderen, A. de Roos, A.J.M. de Craen Progression of brain atrophy and cognitive decline in diabetes mellitus, a 3 year follow-up Neurology 75 2010 997 1002
24. A.C. Ng, D. Auger, V. Delgado Association between diffuse myocardial fibrosis by cardiac magnetic resonance contrast-enhanced T1 mapping and subclinical myocardial dysfunction in diabetic patients: a pilot study Circ Cardiovasc Imaging 5 2012 51 59
25. J.B. Dixon, C.W. Le Roux, F. Rubino, P. Zimmet Bariatric surgery for type 2 diabetes Lancet 379 2012 2300 2311