A fiber-optic-based imaging system for nondestructive assessment of cell-seeded tissue-engineered scaffolds

Tissue Engineering - Part C: Methods

Volumn 18, Issue 9, 2012, Pages 677-687

  Hofmann, Matthias C ^a   Whited, Bryce M ^b   Criswell, Tracy ^c   Rylander, Marissa Nichole ^a,b   Rylander, Christopher G ^a,b   Soker, Shay ^c   Wang, Ge ^b   Xu, Yong ^a  

^a Virginia Polytechnic Institute and State University   (United States)

^b VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY   (United States)

^c WAKE FOREST SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCONVERSION; BIOREACTORS; CELLS; CONFOCAL MICROSCOPY; CYTOLOGY; FIBER OPTICS; FLUORESCENCE; GRAFTS; IMAGING SYSTEMS; OPTICAL MICROSCOPY; TISSUE;

CONFOCAL LASER SCANNING MICROSCOPY; EXCITATION LIGHT; FIBROUS SCAFFOLDS; FLUORESCENCE MAPPING; FLUORESCENT CELLS; GREEN FLUORESCENT PROTEIN; HUMAN ENDOTHELIAL CELLS; IMAGING METHOD; IMAGING MODALITY; IN-VITRO; LABELED CELLS; LINE-OF-SIGHT ACCESS; NON-DESTRUCTIVE MONITORING; NONDESTRUCTIVE ASSESSMENT; NONDESTRUCTIVE IMAGING; NONDESTRUCTIVE METHODS; OPTICAL MICROSCOPES; OPTICAL SCATTERING; SCAFFOLDING MATERIALS; STANDARD OPTICAL MICROSCOPY; TISSUE CONSTRUCTS; TISSUE SCAFFOLDS; TISSUE-ENGINEERED CONSTRUCTS; TISSUE-ENGINEERED SCAFFOLDS; VASCULAR GRAFTS; WORKING DISTANCES;

SCAFFOLDS (BIOLOGY);

GREEN FLUORESCENT PROTEIN; TISSUE SCAFFOLD;

ARTICLE; BIOREACTOR; CHEMISTRY; CONFOCAL MICROSCOPY; CULTURE TECHNIQUE; EQUIPMENT DESIGN; FIBER OPTICS; FLUORESCENCE MICROSCOPY; HUMAN; LIGHT; METABOLISM; METHODOLOGY; MICROCIRCULATION; OPTICS; STATISTICAL MODEL; TISSUE ENGINEERING;

BIOREACTORS; CELL CULTURE TECHNIQUES; EQUIPMENT DESIGN; FIBER OPTIC TECHNOLOGY; GREEN FLUORESCENT PROTEINS; HUMANS; LIGHT; MICROCIRCULATION; MICROSCOPY, CONFOCAL; MICROSCOPY, FLUORESCENCE; MODELS, STATISTICAL; OPTICS AND PHOTONICS; TISSUE ENGINEERING; TISSUE SCAFFOLDS;

EID: 84866975556     PISSN: 19373384     EISSN: 19373392     Source Type: Journal    
DOI: 10.1089/ten.tec.2011.0490     Document Type: Article

References (34)

1. Nerem, R.M., and Sambanis A. Tissue engineering: from biology to biological substitutes. Tissue Eng 1, 3, 1995.
2. Atala, A., Bauer, S.B., Soker, S., Yoo, J.J., and Retik, A.B. Tissue-engineered autologous bladders for patients needing cystoplasty. Lancet 367, 1241, 2006.
3. Laurencin, C.T., and Freeman, J.W. Ligament tissue engineering: an evolutionary materials science approach. Biomaterials 26, 7530, 2005.
4. Raya-Rivera, A., Esquiliano, D.R., Yoo, J.J., Lopez-Bayghen, E., Soker, S., and Atala, A. Tissue-engineered autologous urethras for patients who need reconstruction: an observational study. Lancet 377, 1175, 2011.
5. Elbert, D.L. Bottom-up tissue engineering. Curr Opin Biotechnol 22, 674, 2011.
6. Yang, S., Leong, K.F., Du, Z., and Chua, C.K. The design of scaffolds for use in tissue engineering. Part II. Rapid prototyping techniques. Tissue Eng 8, 1, 2002.
7. Martin, I., Wendt, D., and Heberer, M. The role of bioreactors in tissue engineering. Trends Biotechnol 22, 80, 2004.
8. Sodian, R., Lemke, T., Fritsche, C., Hoerstrup, S.P., Fu, P., Potapov, E.V., Hausmann, H., and Hetzer, R. Tissueengineering bioreactors: a new combined cell-seeding and perfusion system for vascular tissue engineering. Tissue Eng 8, 863, 2002.
9. Goldstein, A.S., and Christ, G. Functional tissue engineering requires bioreactor strategies. Tissue Eng Part A 15, 739, 2009.
10. Angela, H. and Huang, L.E.N. Engineering biological-based vascular grafts using a pulsatile bioreactor. J Vis Exp 52, pii 2646, 2011.
11. Thevenot, P.,Nair, A.,Dey, J., Yang, J., and Tang, L. Method to analyze three-dimensional cell distribution and infiltration in degradable scaffolds. Tissue Eng Part CMethods 14, 319, 2008.
12. Keyes, J.T., Haskett, D.G., Utzinger, U., Azhar, M., and Geest, J.P.V. Adaptation of a planar microbiaxial optomechanical device for the tubular biaxial microstructural and macroscopic characterization of small vascular tissues. J Biomech Eng 133, 075001, 2011.
13. Georgakoudi, I., Rice,W.L., Hronik-Tupaj,M., and Kaplan, D.L. Optical spectroscopy and imaging for the noninvasive evaluation of engineered tissues. Tissue Eng Part B Reviews 14, 321, 2008.
14. Ntziachristos, V. Fluorescence molecular imaging. Annu Rev Biomed Eng 8, 1, 2006.
15. Ntziachristos, V. Going deeper than microscopy: the optical imaging frontier in biology. Nat Methods 7, 603, 2010.
16. König, K., Schenke-Layland, K., Riemann, I., and Stock, U.A. Multiphoton autofluorescence imaging of intratissue elastic fibers. Biomaterials 26, 495, 2005.
17. Schenke-Layland, K., Riemann, I., Stock, U.A., and Kö nig, K. Imaging of cardiovascular structures using near-infrared femtosecond multiphoton laser scanning microscopy. J Biomed Opt 10, 024017, 2005.
18. Kluge, J.A., Leisk, G.G., Cardwell, R.D., Fernandes, A.P., House, M., Ward, A., Dorfmann, A.L., and Kaplan, D.L. Bioreactor system using noninvasive imaging and mechanical stretch for biomaterial screening. Ann Biomed Eng 39, 1390, 2011.
19. Niklason, L.E., Yeh, A.T., Calle, E.A., Bai, Y., Valentin A., and Humphrey, J.D. Enabling tools for engineering collagenous tissues integrating bioreactors, intravital imaging, and biomechanical modeling. Proc Natl Acad Sci USA 107, 3335, 2010.
20. Yazdani, S.K., Tillman, B.W., Berry, J.L., Soker, S., and Geary, R.L. The fate of an endothelium layer after preconditioning. J Vasc Surg 51, 174, 2010.
21. Pham, Q.P., Sharma, U., and Mikos, A.G. Electrospinning of polymeric nanofibers for tissue engineering applications: a review. Tissue Eng 12, 1197, 2006.
22. Wright, L., Young, R., Andric, T., and Freeman, J. Fabrication and mechanical characterization of 3D electrospun scaffolds for tissue engineering. Biomed Mater 5, 055006, 2010.
23. Ji, L., and Gallo, K. An agreement coefficient for image comparison. Photogramm Eng Remote Sensing 72, 823, 2006.
24. MathWorks. Image Registration. Image Processing Toolbox, MATLAB R2011a Documentation: Natick, MA: The Math-Works, Inc., 2011.
25. Kreke, M.R., and Goldstein, A.S. Hydrodynamic shear stimulates osteocalcin expression but not proliferation of bone marrow stromal cells. Tissue Eng 10, 780, 2004.
26. Solomon, C., and Breckon, T. Fundamentals of Digital Image Processing: A Practical Approach with Examples in Matlab. New York: Wiley, 2011, pp. 28-31.
27. Lutolf, M., and Hubbell, J. Synthetic biomaterials as instructive extracellular microenvironments for morphogenesis in tissue engineering. Nat Biotechnol 23, 47, 2005.
28. Griffith, L.G. Emerging design principles in biomaterials and scaffolds for tissue engineering. Ann N Y Acad Sci 961, 83, 2002.
29. Hubbell, J.A. Biomaterials in tissue engineering. Nat Biotechnol 13, 565, 1995.
30. Li, W.J., Laurencin, C.T., Caterson, E.J., Tuan, R.S., and Ko, F.K. Electrospun nanofibrous structure: a novel scaffold for tissue engineering. J Biomed Mater Res 60, 613, 2002.
31. Ma, Z., Kotaki, M., Inai, R., and Ramakrishna, S. Potential of nanofiber matrix as tissue-engineering scaffolds. Tissue Eng 11, 101, 2005.
32. Whited, B.M., Whitney, J.R., Hofmann, M.C., Xu, Y., and Rylander, M.N. Pre-osteoblast infiltration and differentiation in highly porous apatite-coated PLLA electrospun scaffolds. Biomaterials 32, 2294, 2011.
33. Cong, A.X., Hofmann, M.C., Cong, W., Xu, Y., and Wang, G. Monte Carlo fluorescence microtomography. J Biomed Opt 16, 070501, 2011.
34. Cong, A., and Wang, G. A finite-element-based reconstruction method for 3D fluorescence tomography. Opt Expr 13, 9847, 2005.