Successful treatment of liver aspergilloma by caspofungin acetate first-line therapy in a non-immunocompromised patient

International Journal of Molecular Sciences

Volumn 13, Issue 9, 2012, Pages 11063-11070

  Bai, Qing Xian ^a   Huan, Yi ^a   Wang, Jian Hong ^a   Yang, Li Jie ^a   Dong, Hong Juan ^a  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Aspergillosis; Aspergillus fumigatus; Caspofungin acetate; Liver

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; CASPOFUNGIN; IMMUNOGLOBULIN; STANOZOLOL; TUMOR MARKER; ANTIFUNGAL AGENT; ECHINOCANDIN;

ABDOMINAL RADIOGRAPHY; APLASTIC ANEMIA; ARTICLE; ASPERGILLOMA; ASPERGILLUS FUMIGATUS; BLOOD ANALYSIS; BONE MARROW EXAMINATION; CASE REPORT; DISEASE ASSOCIATION; DRUG INTERMITTENT THERAPY; DRUG RESPONSE; ECHOGRAPHY; FEMALE; FOLLOW UP; FUNGUS CULTURE; FUNGUS HYPHAE; FUNGUS ISOLATION; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; LIVER ASPERGILLOMA; MEDICAL HISTORY; MINIMUM INHIBITORY CONCENTRATION; NEEDLE BIOPSY; NUCLEAR MAGNETIC RESONANCE IMAGING; OUTCOME ASSESSMENT; PATIENT ASSESSMENT; PROGNOSIS; SALVAGE THERAPY; TREATMENT PLANNING; ASPERGILLOSIS; COMPLICATION; ISOLATION AND PURIFICATION; LIVER; MICROBIOLOGY; MIDDLE AGED; RADIOGRAPHY;

ASPERGILLUS; ASPERGILLUS FUMIGATUS;

ANEMIA, APLASTIC; ANTIFUNGAL AGENTS; ASPERGILLOSIS; ASPERGILLUS FUMIGATUS; ECHINOCANDINS; FEMALE; HUMANS; LIVER; MIDDLE AGED;

EID: 84866918088     PISSN: 16616596     EISSN: 14220067     Source Type: Journal    
DOI: 10.3390/ijms130911063     Document Type: Article

References (24)

1. Oren, I.; Goldstein, N. Invasive pulmonary aspergillosis. Curr. Opin. Pulm. Med. 2002, 8, 195-200.
2. Chen, S.; Pu, J.L.; Yu, J.; Zhang, J.M. Multiple Aspergillus cerebellar abscesses in a middle-aged female: Case report and literature review. Int. J. Med. Sci. 2011, 8, 635-639.
3. Rossouw, I.; Goedhals, D.; van der Merwe, J.; Stallenberg, V.; Govender, N. A rare, fatal case of invasive spinal aspergillosis in an antiretroviral-naive, HIV-infected man with pre-existing lung colonization. J. Med. Microbiol. 2011, 60, 1534-1538.
4. Wightman, S.C.; Kim, A.W.; Proia, L.A.; Faber, L.P.; Gattuso, P.; Warren, W.H.; Liptay, M.J. An unusual case of Aspergillus fibrosing mediastinitis. Ann. Thorac. Surg. 2009, 88, 1352-1354.
5. Huang, C.W.; Lee, M.A.; Lu, R.H.; Peng, H.C.; Chao, H.S. A case of pulmonary aspergilloma and actinomycosis. J. Med. Microbiol. 2011, 60, 543-546.
6. Locasciulli, A.; Oneto, R.; Bacigalupo, A.; Socié, G.; Korthof, E.; Bekassy, A.; Schrezenmeier, H.; Passweg, J.; Führer, M.; Severe Aplastic Anemia Working Party of the European Blood and Marrow Transplant Group. Outcome of patients with acquired aplastic anemia given first line bone marrow transplantation or immunosuppressive treatment in the last decade: A report from the European Group for Blood and Marrow Transplantation (EBMT). Haematologica 2007, 92, 11-18.
7. Girmenia, C.; Pizzarelli, G.; Pozzi, E.; Cimino, G.; Gentile, G.; Martino, P. Improving outcomes of acute invasive Aspergillus rhinosinusitis in patients with hematologic malignancies or aplastic anemia: The role of voriconazole. Haematologica 2008, 93, 159-160.
8. Bond, R.; Walter, A.; Trigg, M.E. Severe aplastic anemia associated with hepatitis and complicated by pulmonary aspergillosis: Response to immune suppression and antifungal therapy. Del. Med. J. 2002, 74, 339-343.
9. Hori, A.; Kami, M.; Kishi, Y.; Machida, U.; Matsumura, T.; Kashima, T. Clinical significance of extra-pulmonary involvement of invasive aspergillosis: A retrospective autopsy-based study of 107 patients. J. Hosp. Infect. 2002, 50, 175-182.
10. Potenza, L.; Barozzi, P.; Rossi, G.; Palazzi, G.; Vallerini, D.; Riva, G.; Cellini, M.; Morselli, M.; Volzone, F.; Venturelli, C.; et al. Assessment of Aspergillus-specific T cells for diagnosis of invasive aspergillosis in a leukemic child with liver lesions mimicking hepatosplenic candidiasis. Clin. Vaccine Immunol. 2008, 15, 1625-1628.
11. Van der Velden, W.J.; Blijlevens, N.M.; Klont, R.R.; Donnelly, J.P.; Verweij, P.E. Primary hepatic invasive aspergillosis with progression after rituximab therapy for a post transplantation lymphoproliferative disorder. Ann. Hematol. 2006, 85, 621-623.
12. Lee, T.Y.; Yang, S.S.; Chen, G.H.; Hwang, W.L.; Lin, Y.H.; Hwang, J.I. Hepatic abscess caused by Aspergillus fumigatus infection following splenectomy and immunosuppressive therapy. J. Formos. Med. Assoc. 2003, 102, 501-505.
13. Lin, S.J.; Schranz, J.; Teutsch, S.M. Aspergillosis case-fatality rate: Systematic review of the literature. Clin. Infect. Dis. 2001, 32, 358-366.
14. Vandecasteele, S.J.; Boelaert, J.R.; Verrelst, P.; Graulus, E.; Gordts, B.Z. Diagnosis and treatment of Aspergillus flavus sternal wound infections after cardiac surgery. Clin. Infect. Dis. 2002, 35, 887-890.
15. Schwartz, S.; Ruhnke, M.; Ribaud, P.; Corey, L.; Driscoll, T.; Cornely, O.A.; Schuler, U.; Lutsar, I.; Troke, P.; Thiel, E. Improved outcome in central nervous system aspergillosis, using voriconazole treat-ment. Blood 2005, 106, 2641-2645.
16. Zmeili, O.S.; Soubani, A.O. Pulmonary aspergillosis: A clinical update. QJM 2007, 100, 317-334.
17. Jain, L.R.; Denning, D.W. The efficacy and tolerability of voriconazole in the treatment of chronic cavitary pulmonary aspergillosis. J. Infect. 2006, 52, e133-e137.
18. Izumikawa, K.; Ohtsu, Y.; Kawabata, M.; Takaya, H.; Miyamoto, A.; Sakamoto, S.; Kishi, K.; Tsuboi, E.; Homma, S.; Yoshimura, K. Clinical efficacy of micafungin for chronic pulmonary aspergillosis. Med. Mycol. 2007, 45, 273-278.
19. Denning, D.W. Echinocandins: A new class of antifungal. J. Antimicrob. Chemother. 2002, 49, 889-891.
20. Kirkpatrick, W.R.; Perea, S.; Coco, B.J.; Patterson, T.F. Efficacy of caspofungin alone and in combination with voriconazole in a Guinea pig model of invasive aspergillosis. Antimicrob. Agents Chemother. 2002, 46, 2564-2568.
21. Steinbach, W.J.; Perfect, J.R.; Schell, W.A.; Walsh, T.J.; Benjamin, D.K., Jr. In vitro analyses, animal models, and 60 clinical cases of invasive Aspergillus terreus infection. Antimicrob. Agents Chemother. 2004, 48, 3217-3225.
22. Steinbach, W.J.; Benjamin, D.K., Jr.; Kontoyiannis, D.P.; Perfect, J.R.; Lutsar, I.; Marr, K.A.; Lionakis, M.S.; Torres, H.A.; Jafri, H.; Walsh, T.J. Infections due to Aspergillus terreus: A multicenter retrospective analysis of 83 cases. Clin. Infect. Dis. 2004, 39, 192-198.
23. Castagnola, E.; Machetti, M.; Cappelli, B.; Molinari, A.C.; Morreale, G.; Dodero, P.; Tomà, P.; Faraci, M. Caspofungin associated with liposomal amphotericin B or voriconazole for treatment of refractory fungal pneumonia in children with acute leukaemia or undergoing allogeneic bone marrow transplant. Clin. Microbiol. Infect. 2004, 10, 255-257.
24. Candoni, A.; Mestroni, R.; Damiani, D.; Tiribelli, M.; Michelutti, A.; Silvestri, F.; Castelli, M.; Viale, P.; Fanin, R. Caspofungin as first line therapy of pulmonary invasive fungal infections in 32 immunocompromised patients with hematologic malignancies. Eur. J. Haematol. 2005, 75, 227-233.