Artesunate dosing in severe falciparum malaria

Journal of Infectious Diseases

Volumn 206, Issue 4, 2012, Pages 618-619

  Dondorp, Arjen M ^a,b   Maude, Richard J ^a,b   Hendriksen, Ilse C E ^a   Day, Nicholas P ^a,b   White, Nicholas J ^a,b  

^a MAHIDOL UNIVERSITY   (Thailand)

^b UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ARTEMETHER; ARTESUNATE; DIHYDROARTEMISININ; QUININE; ANTIMALARIAL AGENT; ARTEMISININ DERIVATIVE;

CHILDHOOD MORTALITY; COST BENEFIT ANALYSIS; COST CONTROL; DISEASE SEVERITY; DRUG BLOOD LEVEL; DRUG COST; DRUG DOSE REGIMEN; DRUG EFFICACY; DRUG SAFETY; HUMAN; LETTER; MALARIA FALCIPARUM; NONHUMAN; PARASITE CLEARANCE; PARASITE SURVIVAL; PRACTICE GUIDELINE; PRIORITY JOURNAL; SCHIZONT; TREATMENT RESPONSE; WORLD HEALTH ORGANIZATION; FEMALE; MALE; NOTE; PARASITE LOAD;

ANTIMALARIALS; ARTEMISININS; FEMALE; HUMANS; MALARIA, FALCIPARUM; MALE; PARASITE LOAD;

EID: 84866902435     PISSN: 00221899     EISSN: None     Source Type: Journal    
DOI: 10.1093/infdis/jis389     Document Type: Letter

References (6)

1. Dondorp A, Nosten F, Stepniewska K, Day NWhite NJ. Artesunate versus quinine for treatment of severe falciparum malaria: a randomised trial. Lancet 2005; 366:717-25.
2. Dondorp AM, Fanello CI, Hendriksen IC, et al Artesunate versus quinine in the treatment of severe falciparum malaria in African children (AQUAMAT): an open-label, randomised trial. Lancet 2010; 376:1647-57.
3. Angus BJ, Thaiaporn I, Chanthapadith K, Suputtamongkol Y, White NJ. Oral artesunate dose-response relationship in acute falciparum malaria. Antimicrob Agents Chemother 2002; 46:778-82.
4. Kremsner PG, Taylor T, Issifou S, et al A simplified intravenous artesunate regimen for severe malaria. J Infect Dis 2012; 205:312-9.
5. ter Kuile F, White NJ, Holloway P, Pasvol G, Krishna S. Plasmodium falciparum: in vitro studies of the pharmacodynamic properties of drugs used for the treatment of severe malaria. Exp Parasitol 1993; 76:85-95.
6. Lubell Y, Riewpaiboon A, Dondorp AM, et al Cost-effectiveness of parenteral artesunate for treating children with severe malaria in sub- Saharan Africa. Bull World Health Organ 2011; 89:504-12.