Supportive evidence for the association between the Gln2Pro polymorphism in the SIGMAR1 gene and schizophrenia in the Japanese population: A case-control study and an updated meta-analysis

Schizophrenia Research

Volumn 141, Issue 2-3, 2012, Pages 279-280

  Watanabe, Yuichiro ^a,b   Nunokawa, Ayako ^a,c   Kaneko, Naoshi ^a,d   Shibuya, Masako ^a,e   Egawa, Jun ^a,f   Someya, Toshiyuki ^a  

^a NIIGATA UNIVERSITY GRADUATE SCHOOL OF MEDICAL AND DENTAL SCIENCES   (Japan)

^b NIIGATA UNIVERSITY   (Japan)

^c Niigata Psychiatric Center   (Japan)

^d Oojima Hospital   (Japan)

^e NIIGATA UNIVERSITY   (Japan)

^f National Saigata Medical Center   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

GLUTAMINE; PHOSPHODIESTERASE I; PROLINE; SIGMA NON OPIOID INTRACELLULAR RECEPTOR 1; SIGMA OPIATE RECEPTOR; UNCLASSIFIED DRUG;

ADULT; ALLELE; CASE CONTROL STUDY; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE PREDISPOSITION; FEMALE; GENE; GENE FREQUENCY; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENETIC SUSCEPTIBILITY; GENOTYPE; HUMAN; JAPANESE; LETTER; MAJOR CLINICAL STUDY; MALE; META ANALYSIS; PATHOGENESIS; PRIORITY JOURNAL; SCHIZOPHRENIA; SENSITIVITY ANALYSIS; SIGMAR1 GENE;

ADULT; ASIAN CONTINENTAL ANCESTRY GROUP; CASE-CONTROL STUDIES; FEMALE; GENE FREQUENCY; GENETIC ASSOCIATION STUDIES; GENOTYPE; GLUTAMINE; HUMANS; MALE; MIDDLE AGED; POLYMORPHISM, GENETIC; PROLINE; RECEPTORS, SIGMA; SCHIZOPHRENIA;

EID: 84866899535     PISSN: 09209964     EISSN: 15732509     Source Type: Journal    
DOI: 10.1016/j.schres.2012.06.043     Document Type: Letter

References (9)

1. Hayashi T., Tsai S.Y., Mori T., Fujimoto M., Su T.P. Targeting ligand-operated chaperone sigma-1 receptors in the treatment of neuropsychiatric disorders. Expert Opin. Ther. Targets 2011, 15(5):557-577.
2. Ishiguro H., Ohtsuki T., Toru M., Itokawa M., Aoki J., Shibuya H., Kurumaji A., Okubo Y., Iwawaki A., Ota K., Shimizu H., Hamaguchi H., Arinami T. Association between polymorphisms in the type 1 sigma receptor gene and schizophrenia. Neurosci. Lett. 1998, 257(1):45-48.
3. Ohi K., Hashimoto R., Yasuda Y., Fukumoto M., Yamamori H., Umeda-Yano S., Kamino K., Ikezawa K., Azechi M., Iwase M., Kazui H., Kasai K., Takeda M. The SIGMAR1 gene is associated with a risk of schizophrenia and activation of the prefrontal cortex. Prog. Neuropsychopharmacol. Biol. Psychiatry 2011, 35(5):1309-1315.
4. 1 receptor gene in schizophrenia: an association study. Am. J. Med. Genet. 2000, 96(1):118-122.
5. 1 receptor gene variants and schizophrenia. Psychiatry Clin. Neurosci. 2004, 58(4):359-363.
6. Takizawa R., Hashimoto K., Tochigi M., Kawakubo Y., Marumo K., Sasaki T., Fukuda M., Kasai K. Association between sigma-1 receptor gene polymorphism and prefrontal hemodynamic response induced by cognitive activation in schizophrenia. Prog. Neuropsychopharmacol. Biol. Psychiatry 2009, 33(3):491-498.
7. Uchida N., Ujike H., Nakata K., Takaki M., Nomura A., Katsu T., Tanaka Y., Imamura T., Sakai A., Kuroda S. No association between the sigma receptor type 1 gene and schizophrenia: results of analysis and meta-analysis of case-control studies. BMC Psychiatry 2003, 3:13.
8. Watanabe Y., Muratake T., Kaneko N., Nunokawa A., Someya T. No association between the brain-derived neurotrophic factor gene and schizophrenia in a Japanese population. Schizophr. Res. 2006, 84(1):29-35.
9. Watanabe Y., Nunokawa A., Kaneko N., Someya T. Meta-analysis of case-control association studies between the C270T polymorphism of the brain-derived neurotrophic factor gene and schizophrenia. Schizophr. Res. 2007, 95(1-3):250-252.