Polymorphisms of the σ1 receptor gene in schizophrenia: An association study

American Journal of Medical Genetics - Neuropsychiatric Genetics

Volumn 96, Issue 1, 2000, Pages 118-122

  Ohmori, Osamu ^a   Shinkai, Takahiro ^a   Suzuki, Takashi ^a   Okano, Chie ^a   Kojima, Hideki ^a   Terao, Takeshi ^a   Nakamura, Jun ^a  

^a UNIVERSITY OF OCCUPATIONAL AND ENVIRONMENTAL HEALTH   (Japan)

Author keywords

receptors; 1 receptor; Association study; Polymorphism; Schizophrenia

Indexed keywords

SIGMA OPIATE RECEPTOR;

ADULT; ARTICLE; CONTROLLED STUDY; FEMALE; GENE FREQUENCY; GENE LINKAGE DISEQUILIBRIUM; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; HOMOZYGOSITY; HUMAN; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; SCHIZOPHRENIA; SEQUENCE ANALYSIS; SINGLE STRAND CONFORMATION POLYMORPHISM;

ADULT; AGED; ALLELES; BASE SEQUENCE; DNA PRIMERS; FEMALE; GENE FREQUENCY; GENOTYPE; HUMANS; MALE; MIDDLE AGED; POLYMORPHISM, SINGLE-STRANDED CONFORMATIONAL; RECEPTORS, SIGMA; SCHIZOPHRENIA; SEQUENCE ANALYSIS, DNA;

EID: 0034615092     PISSN: 15524841     EISSN: 1552485X     Source Type: Journal    
DOI: 10.1002/(SICI)1096-8628(20000207)96:1<118::AID-AJMG23>3.0.CO;2-C     Document Type: Article

References (25)

1. Chouinard G, Annable, L. 1984. An early phase II clinical trial of BW234 in the treatment of acute schizophrenia in newly admitted patients. Psychopharmacology 84:282-284.
2. Frieboes R-M, Murck H, Wiedemann K, Holsboer F, Steiger A. 1997. Open clinical trial on the sigma ligand panamesine in patients with schizophrenia. Psychopharmacology 132:82-88.
3. 3H]dopamine from guinea pig striatal slices is modulated by sigmal receptor agonists. Naunyn Schmiedebergs Arch Pharmacol 356:455-461.
4. 4 sites in schizophrenic brains. Eur J Pharmacol 314:R3-R5, 1996.
5. Ishiguro H, Ohtsuka T, Toru M, Itokawa M, Aoki J, Shibuya H, Kurumaji A, Okubo Y, Iwawaki A, Ota K, Shimizu H, Hamaguchi H, Arinami T. 1998. Association between polymorphisms in the type 1 sigma receptor gene and schizophrenia. Neurosci Lett 257:45-48.
6. Keats AS, Telford, J. 1964. Narcotic antagonists as analgesics: clinical aspects. In: Gould RF, editor. Molecular modification in drug design (Advances in chemistry series 45). Washington DC: American Chemical Society. p 170-176.
7. Kitaichi K, Noda Y, Hasegawa T, Furukawa H, Nabeshima T. 1996. In vivo functional interaction between phencyclidine binding sites and σ receptors to produce head-weaving behavior in rats. Eur J Pharmacol 318:205-211.
8. Martin WR, Eades CG, Thompson JA, Huppler RE, Gilbert PE. 1976. The effects of morphine- and nalorphine-like drugs in the nondependent and morphine-dependent chronic spinal dog. J Pharmacol Exp Ther 197:517-532.
9. Mendelsohn LG, Kalra V, Johnson BG, Kerchner GA. 1985. Sigma opioid receptor: characterization and co-identity with the phencyclidine receptor. J Pharmacol Exp Ther 233:597-602.
10. Modell A, Naber D, Holzbach R. 1996. Efficacy and safety of an opiate sigma-receptor antagonist (SL 82.0715) in schizophrenic patients with negative symptoms: an open dose-range study. Pharmacopsychiatry 29:63-66.
11. Moises HW, Yang L, Kristbjarnarson H, Wiese C, Byerley W, Macciardi F, Arolt V, Blackwood D, Liu X, Sjögren B, Aschauer HN, Hwu H-G, et al. 1995. An international two-stage genome search for schizophrenia susceptibility genes. Nat Genet 11:321-324.
12. Nanko S, Kunugi H, Sasaki T, Fukuda R, Kawate T, Kazamatsuri H. 1993. Pericentric region of chromosome 9 is a possible candidate region for linkage study of schizophrenia. Biol Psychiatry 33:655-658.
13. Prasad PD, Li HW, Fei Y-J, Ganapathy ME, Fujita T, Plumley LH, Yang-Feng TL, Leigach FH, Ganapathy V. 1998. Exon-intron structure, analysis of promoter region, and chromosomal localization of the human type 1 σ receptor gene. J Neurochem 70:443-451.
14. Quirion R, Chicheportiche R, Contreras PC, Johnson KM, Lodge D, Tam SW, Woods JH, Zukin SR. 1987. Classification and nomenclature of phencyclidine and sigma receptor sites. Trends Phramacol Sci 10:444-446.
15. Quirion R, Bowen WD, Itzhak Y, Junien JL, Musacchio JM, Rothman RB, Su TP, Tam SW, Taylor DP. 1992. A proposal for the classification of sigma binding sites. Trends Pharmacol Sci 13:85-86.
16. 3H]Ditolylguanidine binding to human brain σ sites is diminished after haloperidol treatment. Eur J Pharmacol 194:235-236.
17. Seth P, Frei YJ, Li HW, Huang W, Leibach FH, Ganapathy V. 1998. Cloning and functional characterization of a σ receptor from rat brain. J Neurochem 70:922-931.
18. Seth P, Leibach FH, Ganapathy V. 1997. Cloning and structural analysis of the cDNA and the gene encoding the murine type 1 sigma receptor. Biochem Biophys Res Commun 241:535-540.
19. Simpson MDC, Slater P, Royston MC, Deakin JFW. 1992. Alternation in phencyclidine and sigma binding sites in schizophrenic brains. Schizophr Res 6:41-42.
20. Tam SW. 1983. Naloxone-inaccessible σ receptor in rat central nervous system. Proc Natl Acad Sci USA 80:6703-6707.
21. 3H]haloperidol binding in guinea pig brain membranes. Proc Natl Acad Sci USA 81:5618-5621.
22. Ujike H, Kanzaki A, Okumura K, Akiyama K, Otsuki S. 1992. Sigma (σ) antagonist BMY 14802 prevents methamphetamine-induced sensitization. Life Sci 50:129-134.
23. 3H] dopamine release from mesolimbic and mesocortical areas of guinea pig brain by sigma receptors. Schizophr Res 21:51-62.
24. Weissman AD, Casanova MF, Kleinman JE, London ED, De Souza EB. 1991. Selective loss of cerebral cortical sigma, but not PCP binding sites in schizophrenia. Biol Psychiatry 29:41-54.
25. Woolf B. 1955. On estimating the relationship between blood group and disease. Ann Hum Genet 19:251-253.