Blood levels of copeptin on admission predict outcomes in out-of-hospital cardiac arrest survivors treated with therapeutic hypothermia

Critical Care

Volumn 16, Issue 5, 2012, Pages

  Ostadal, Petr ^a   Kruger, Andreas ^a   Zdrahalova, Vladimira ^a   Janotka, Marek ^a   Vondrakova, Dagmar ^a   Neuzil, Petr ^a   Prucha, Miroslav ^a  

^a NA HOMOLCE HOSPITAL   (Czech Republic)

Author keywords

[No Author keywords available]

Indexed keywords

COPEPTIN; BIOLOGICAL MARKER; GLYCOPEPTIDE;

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; FEMALE; HORMONE BLOOD LEVEL; HOSPITAL ADMISSION; HUMAN; IMMUNOASSAY; INDUCED HYPOTHERMIA; MALE; NEUROLOGIC DISEASE; OUT OF HOSPITAL CARDIAC ARREST; PRIORITY JOURNAL; SENSITIVITY AND SPECIFICITY; SURVIVAL PREDICTION; SURVIVOR; BLOOD; MIDDLE AGED; MORTALITY; OUT-OF-HOSPITAL CARDIAC ARREST; PREDICTIVE VALUE; TREATMENT OUTCOME; TRENDS; VERY ELDERLY;

AGED; AGED, 80 AND OVER; BIOLOGICAL MARKERS; FEMALE; GLYCOPEPTIDES; HUMANS; HYPOTHERMIA, INDUCED; MALE; MIDDLE AGED; OUT-OF-HOSPITAL CARDIAC ARREST; PATIENT ADMISSION; PREDICTIVE VALUE OF TESTS; SURVIVORS; TREATMENT OUTCOME;

EID: 84866886518     PISSN: 13648535     EISSN: 1466609X     Source Type: Journal    
DOI: 10.1186/cc11671     Document Type: Article

References (17)

1. Neumar RW, Nolan JP, Adrie C, Aibiki M, Berg RA, Bottiger BW, Callaway C, Clark RS, Geocadin RG, Jauch EC, Kern KB, Laurent I, Longstreth WT, Merchant RM, Morley P, Morrison LJ, Nadkarni V, Peberdy MA, Rivers EP, Rodriguez-Nunez A, Sellke FW, Spaulding C, Sunde K, Vanden Hoek T. Post-cardiac arrest syndrome: epidemiology, pathophysiology, treatment, and prognostication. A consensus statement from the International Liaison Committee on Resuscitation (American Heart Association, Australian and New Zealand Council on Resuscitation, European Resuscitation Council, Heart and Stroke Foundation of Canada, InterAmerican Heart Foundation, Resuscitation Council of Asia, and the Resuscitation Council of Southern Africa); the American Heart Association Emergency Cardiovascular Care Committee; the Council on Cardiovascular Surgery and Anesthesia; the Council on Cardiopulmonary, Perioperative, and Critical Care; the Council on Clinical Cardiology; and the Stroke Council. Circulation 2008, 118:2452-2483. 10.1161/CIRCULATIONAHA.108.190652, 18948368.
2. Nolan JP, Neumar RW, Adrie C, Aibiki M, Berg RA, Bottiger BW, Callaway C, Clark RS, Geocadin RG, Jauch EC, Kern KB, Laurent I, Longstreth WT, Merchant RM, Morley P, Morrison LJ, Nadkarni V, Peberdy MA, Rivers EP, Rodriguez-Nunez A, Sellke FW, Spaulding C, Sunde K, Hoek TV. Post-cardiac arrest syndrome: epidemiology, pathophysiology, treatment, and prognostication. A scientific statement from the International Liaison Committee on Resuscitation; the American Heart Association Emergency Cardiovascular Care Committee; the Council on Cardiovascular Surgery and Anesthesia; the Council on Cardiopulmonary, Perioperative, and Critical Care; the Council on Clinical Cardiology; the Council on Stroke. Resuscitation 2008, 79:350-379. 10.1016/j.resuscitation.2008.09.017, 18963350.
3. Bernard SA, Gray TW, Buist MD, Jones BM, Silvester W, Gutteridge G, Smith K. Treatment of comatose survivors of out-of-hospital cardiac arrest with induced hypothermia. N Engl J Med 2002, 346:557-563. 10.1056/NEJMoa003289, 11856794.
4. HACA Study Group Mild therapeutic hypothermia to improve the neurologic outcome after cardiac arrest. N Engl J Med 2002, 346:549-556. HACA Study Group.
5. Oddo M, Rossetti AO. Predicting neurological outcome after cardiac arrest. Curr Opin Crit Care 2011, 17:254-259. 10.1097/MCC.0b013e328344f2ae, 21346563.
6. Stolz D, Christ-Crain M, Morgenthaler NG, Leuppi J, Miedinger D, Bingisser R, Muller C, Struck J, Muller B, Tamm M. Copeptin, C-reactive protein, and procalcitonin as prognostic biomarkers in acute exacerbation of COPD. Chest 2007, 131:1058-1067. 10.1378/chest.06-2336, 17426210.
7. Katan M, Fluri F, Morgenthaler NG, Schuetz P, Zweifel C, Bingisser R, Muller K, Meckel S, Gass A, Kappos L, Steck AJ, Engelter ST, Muller B, Christ-Crain M. Copeptin: a novel, independent prognostic marker in patients with ischemic stroke. Ann Neurol 2009, 66:799-808.
8. Potocki M, Reichlin T, Thalmann S, Zellweger C, Twerenbold R, Reiter M, Steuer S, Bassetti S, Drexler B, Stelzig C, Freese M, Winkler K, Haaf P, Balmelli C, Hochholzer W, Osswald S, Mueller C. Diagnostic and prognostic impact of copeptin and high-sensitivity cardiac troponin T in patients with pre-existing coronary artery disease and suspected acute myocardial infarction. Heart 2012, 98:558-565. 10.1136/heartjnl-2011-301269, 22337952.
9. Miller WL, Hartman KA, Grill DE, Struck J, Bergmann A, Jaffe AS. Serial measurements of midregion proANP and copeptin in ambulatory patients with heart failure: incremental prognostic value of novel biomarkers in heart failure. Heart 2012, 98:389-394. 10.1136/heartjnl-2011-300823, 3276775, 22194151.
10. Alehagen U, Dahlstrom U, Rehfeld JF, Goetze JP. Association of copeptin and N-terminal proBNP concentrations with risk of cardiovascular death in older patients with symptoms of heart failure. JAMA 2011, 305:2088-2095. 10.1001/jama.2011.666, 21610241.
11. Kruger A, Ostadal P, Vondrakova D, Janotka M, Herget J. Nitrotyrosine and nitrate/nitrite levels in cardiac arrest survivors treated with endovascular hypothermia. Physiol Res 2012, 61:425-430.
12. Jennett B, Bond M. Assessment of outcome after severe brain damage. Lancet 1975, 1:480-484.
13. Katan M, Christ-Crain M. The stress hormone copeptin: a new prognostic biomarker in acute illness. Swiss Med Wkly 2010, 140:w13101.
14. Narayan H, Dhillon OS, Quinn PA, Struck J, Squire IB, Davies JE, Ng LL. C-terminal provasopressin (copeptin) as a prognostic marker after acute non-ST elevation myocardial infarction: Leicester Acute Myocardial Infarction Peptide II (LAMP II) study. Clin Sci (Lond) 2011, 121:79-89.
15. Nickel CH, Ruedinger J, Misch F, Blume K, Maile S, Schulte J, Kohrle J, Hartmann O, Giersdorf S, Bingisser R. Copeptin and peroxiredoxin-4 independently predict mortality in patients with nonspecific complaints presenting to the emergency department. Acad Emerg Med 2011, 18:851-859. 10.1111/j.1553-2712.2011.01126.x, 21843221.
16. Jarai R, Mahla E, Perkmann T, Archan S, Tentzeris I, Huber K, Metzler H. Usefulness of pre-operative copeptin concentrations to predict post-operative outcome after major vascular surgery. Am J Cardiol 2011, 108:1188-1195. 10.1016/j.amjcard.2011.06.024, 21798504.
17. Kim JJ, Hyun SY, Hwang SY, Jung YB, Shin JH, Lim YS, Cho JS, Yang HJ, Lee G. Hormonal responses upon return of spontaneous circulation after cardiac arrest: a retrospective cohort study. Crit Care 2011, 15:R53. 10.1186/cc10019, 3221984, 21299901.